RU2004137816A - Композиции и способы покрытия медицинских имплантатов - Google Patents
Композиции и способы покрытия медицинских имплантатов Download PDFInfo
- Publication number
- RU2004137816A RU2004137816A RU2004137816/15A RU2004137816A RU2004137816A RU 2004137816 A RU2004137816 A RU 2004137816A RU 2004137816/15 A RU2004137816/15 A RU 2004137816/15A RU 2004137816 A RU2004137816 A RU 2004137816A RU 2004137816 A RU2004137816 A RU 2004137816A
- Authority
- RU
- Russia
- Prior art keywords
- medical implant
- fluoropyrimidine
- polymer
- implant according
- anthracycline
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Paints Or Removers (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
- Electrotherapy Devices (AREA)
Claims (31)
1. Медицинский имплантат, который высвобождает антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевину или комплекс платины.
2. Медицинский имплантат по п.1, где указанный имплантат обернут или покрыт целиком или частично композиций, содержащей антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевину или комплекс платины.
3. Медицинский имплантат по п.1 или 2, где указанный антрациклин представляет собой доксорубицин или митоксантрон.
4. Медицинский имплантат по п. 1 или 2, где указанный фторпиримидин представляет собой 5-фторурацил.
5. Медицинский имплантат по п. 1 или 2, где указанный антагонист фолиевой кислоты представляет собой метотрексат.
6. Медицинский имплантат по п. 1 или 2, где указанный подофилотоксин представляет собой этопозид.
7. Медицинский имплантат по п. 2, где указанная композиция дополнительно содержит полимер.
8. Медицинский имплантат по п.7, где указанный полимер представляет собой биоразлагаемый или бионеразлагаемый полимер.
9. Медицинский имплантат по п. 7, где указанный полимер является полиуретаном.
10. Медицинский имплантат по п.7, где указанный полимер является поли(лактид-со-гликолидом).
11. Медицинский имплантат по любому из пп. 7-10, где указанный фторпиримидин представляет собой 5-фторурацил.
12. Медицинский имплантат по п.1 или 2, где указанный медицинский имплантат представляет собой сосудистый катетер, искусственный сердечный клапан, кардиостимулятор, имплантируемый дефибриллятор сердца, сосудистый имплантат, ушной, носовой или горловой имплантат, урологический имплантат, эндотрахеальную или трахеостомическую трубку, катетер для диализа, шунт для ЦНС, ортопедический имплантат или глазной имплантат.
13. Композиция, содержащая полимер и антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевину или комплекс платины, где указанные антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевина или комплекс платины находятся в указанной композиции в концентрации менее чем 10-4 М.
14. Композиция по п.13, где указанные антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевину или комплекс платины, где указанные антрациклин, фторпиримидин, антагонист фолиевой кислоты, подофилотоксин, камптотецин, гидроксимочевина или комплекс платины находятся в концентрации менее чем 10-5 М, 10-6 М или 10-7 М.
15. Композиция по п. 13 или 14, где указанный фторпиримидин представляет собой 5-фторурацил.
16. Способ снижения или подавления инфекции, связанной с медицинским имплантатом, включающий стадию введения пациенту медицинского имплантата, который обернут или покрыт антрациклином, фторпиримидином, антагонистом фолиевой кислоты, подофилотоксином, камптотецином, гидроксимочевиной или комплексом платины.
17. Способ по п. 16, где указанный фторпиримидин представляет собой 5-фторурацил.
18. Медицинский имплантат по п. 1 для применения в способе снижения или подавления инфекции, связанной с медицинским имплантатом.
19. Медицинский имплантат по п. 18, где указанная композиция дополнительно включает полимер.
20. Медицинский имплантат по п.19, где указанный полимер представляет собой биоразлагаемый или бионеразлагаемый полимер.
21. Медицинский имплантат по п. 19, где указанный полимер является полиуретаном.
22. Медицинский имплантат по п.19, где указанный полимер является поли(лактид-со-гликолидом).
23. Медицинский имплантат по одному из пп. 19-22, где указанный фторпиримидин представляет собой 5-фторурацил.
24. Применение композиции по п.13 для получения медицинского имплантата для снижения или подавления инфекции, связанной с медицинским имплантатом.
25. Применение по п. 24, где указанный полимер представляет собой биоразлагаемый или бионеразлагаемый полимер.
26. Применение по п. 24, где указанный полимер является полиуретаном.
27. Применение по п. 24, где указанный полимер является поли(лактид-со-гликолидом).
28. Применение по одному из пп. 24-27, где указанный фторпиримидин представляет собой 5-фторурацил.
29. Способ изготовления медицинских имплантатов, включающий обертывание или покрытие медицинского имплантата антрациклином, фторпиримидином, антагонистом фолиевой кислоты, подофилотоксином, камптотецином, гидроксимочевиной или комплексом платины.
30. Способ по п. 29, где указанный фторпиримидин представляет собой 5-фторурацил.
31. Способ по п. 29, где указанный медицинский имплантат обертывают или покрывают погружением или пропитыванием.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38341902P | 2002-05-24 | 2002-05-24 | |
US60/383,419 | 2002-05-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2004137816A true RU2004137816A (ru) | 2005-06-27 |
RU2341296C2 RU2341296C2 (ru) | 2008-12-20 |
Family
ID=29584566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2004137816/15A RU2341296C2 (ru) | 2002-05-24 | 2003-05-27 | Композиции и способы покрытия медицинских имплантатов |
Country Status (20)
Country | Link |
---|---|
US (10) | US20040043052A1 (ru) |
EP (2) | EP2075014B9 (ru) |
JP (2) | JP2005527302A (ru) |
KR (1) | KR20100110378A (ru) |
CN (2) | CN100341589C (ru) |
AT (1) | ATE515277T1 (ru) |
AU (2) | AU2003234670B2 (ru) |
BR (1) | BR0311285A (ru) |
CA (1) | CA2484761C (ru) |
DE (1) | DE60328486D1 (ru) |
DK (1) | DK1509256T3 (ru) |
ES (2) | ES2330326T3 (ru) |
HK (1) | HK1082435A1 (ru) |
IL (1) | IL165120A (ru) |
MX (1) | MXPA04011651A (ru) |
NZ (2) | NZ536308A (ru) |
PT (1) | PT1509256E (ru) |
RU (1) | RU2341296C2 (ru) |
WO (1) | WO2003099346A2 (ru) |
ZA (1) | ZA200409291B (ru) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2478385C2 (ru) * | 2007-05-22 | 2013-04-10 | Новартис Аг | Соединения триазола для лечения образования биопленок |
RU2551938C1 (ru) * | 2014-07-14 | 2015-06-10 | Общество с ограниченной ответственностью "Инновационная компания "Современные технологии" | Многоцелевой сосудистый имплант |
Families Citing this family (229)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10105592A1 (de) | 2001-02-06 | 2002-08-08 | Achim Goepferich | Platzhalter zur Arzneistofffreigabe in der Stirnhöhle |
DE60207893T2 (de) | 2002-03-14 | 2006-08-17 | Yeung, Teresa T., San Jose | Nahtanker und adaptationsvorrichtung |
US8313760B2 (en) * | 2002-05-24 | 2012-11-20 | Angiotech International Ag | Compositions and methods for coating medical implants |
RU2341296C2 (ru) * | 2002-05-24 | 2008-12-20 | Энджиотек Интернэшнл Аг | Композиции и способы покрытия медицинских имплантатов |
JP2006515186A (ja) * | 2002-09-26 | 2006-05-25 | アンジオテック インターナショナル アクツィエン ゲゼルシャフト | 血管周囲ラップ |
US8317816B2 (en) * | 2002-09-30 | 2012-11-27 | Acclarent, Inc. | Balloon catheters and methods for treating paranasal sinuses |
US6992127B2 (en) * | 2002-11-25 | 2006-01-31 | Ast Products, Inc. | Polymeric coatings containing a pH buffer agent |
EP1578850B1 (en) * | 2002-12-20 | 2017-02-22 | Coloplast A/S | A hydrophilic coating and a method for the preparation thereof |
JP2007525429A (ja) * | 2003-03-11 | 2007-09-06 | キューエルティー ユーエスエー,インコーポレイテッド. | 細胞スケジュール依存性抗癌剤のための処方 |
EP3103422A1 (en) | 2003-03-14 | 2016-12-14 | Intersect ENT, Inc. | Sinus delivery of sustained release therapeutics |
US20040180131A1 (en) * | 2003-03-14 | 2004-09-16 | Medtronic Ave. | Stent coating method |
US8518097B2 (en) | 2003-04-25 | 2013-08-27 | Medtronic Vascular, Inc. | Plasticized stent coatings |
US20050181977A1 (en) * | 2003-11-10 | 2005-08-18 | Angiotech International Ag | Medical implants and anti-scarring agents |
WO2005046746A2 (en) * | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
US20050209664A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Electrical devices and anti-scarring agents |
US20070026043A1 (en) * | 2003-11-20 | 2007-02-01 | Angiotech International Ag | Medical devices combined with diblock copolymer compositions |
US20050158356A1 (en) * | 2003-11-20 | 2005-07-21 | Angiotech International Ag | Implantable sensors and implantable pumps and anti-scarring agents |
US7215655B2 (en) * | 2004-01-09 | 2007-05-08 | Interdigital Technology Corporation | Transport format combination selection in a wireless transmit/receive unit |
AU2005210668A1 (en) * | 2004-01-30 | 2005-08-18 | Angiotech International Ag | Compositions and methods for treating contracture |
US9101384B2 (en) | 2004-04-21 | 2015-08-11 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat |
US8747389B2 (en) | 2004-04-21 | 2014-06-10 | Acclarent, Inc. | Systems for treating disorders of the ear, nose and throat |
US8146400B2 (en) | 2004-04-21 | 2012-04-03 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US9351750B2 (en) | 2004-04-21 | 2016-05-31 | Acclarent, Inc. | Devices and methods for treating maxillary sinus disease |
US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
US20060004323A1 (en) | 2004-04-21 | 2006-01-05 | Exploramed Nc1, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US8764729B2 (en) | 2004-04-21 | 2014-07-01 | Acclarent, Inc. | Frontal sinus spacer |
US9089258B2 (en) | 2004-04-21 | 2015-07-28 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US20070208252A1 (en) | 2004-04-21 | 2007-09-06 | Acclarent, Inc. | Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses |
US7559925B2 (en) | 2006-09-15 | 2009-07-14 | Acclarent Inc. | Methods and devices for facilitating visualization in a surgical environment |
US20060063973A1 (en) | 2004-04-21 | 2006-03-23 | Acclarent, Inc. | Methods and apparatus for treating disorders of the ear, nose and throat |
US8864787B2 (en) | 2004-04-21 | 2014-10-21 | Acclarent, Inc. | Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis |
US9554691B2 (en) | 2004-04-21 | 2017-01-31 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US9399121B2 (en) | 2004-04-21 | 2016-07-26 | Acclarent, Inc. | Systems and methods for transnasal dilation of passageways in the ear, nose or throat |
US20190314620A1 (en) | 2004-04-21 | 2019-10-17 | Acclarent, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US10188413B1 (en) | 2004-04-21 | 2019-01-29 | Acclarent, Inc. | Deflectable guide catheters and related methods |
US8702626B1 (en) | 2004-04-21 | 2014-04-22 | Acclarent, Inc. | Guidewires for performing image guided procedures |
US7419497B2 (en) | 2004-04-21 | 2008-09-02 | Acclarent, Inc. | Methods for treating ethmoid disease |
US7462175B2 (en) | 2004-04-21 | 2008-12-09 | Acclarent, Inc. | Devices, systems and methods for treating disorders of the ear, nose and throat |
US7361168B2 (en) | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
US8894614B2 (en) | 2004-04-21 | 2014-11-25 | Acclarent, Inc. | Devices, systems and methods useable for treating frontal sinusitis |
US7410480B2 (en) * | 2004-04-21 | 2008-08-12 | Acclarent, Inc. | Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders |
US7803150B2 (en) | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
US20070167682A1 (en) | 2004-04-21 | 2007-07-19 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US8932276B1 (en) | 2004-04-21 | 2015-01-13 | Acclarent, Inc. | Shapeable guide catheters and related methods |
US20060020328A1 (en) * | 2004-07-23 | 2006-01-26 | Tan Sharon M L | Composite vascular graft having bioactive agent |
WO2006018026A1 (en) * | 2004-08-19 | 2006-02-23 | Coloplast A/S | Absorbent fiber material and use thereof in wound dressings |
WO2006024489A2 (en) * | 2004-08-30 | 2006-03-09 | Interstitial Therapeutics | Methods and compositions for the treatment of cell proliferation |
US20060051392A1 (en) * | 2004-09-03 | 2006-03-09 | Medtronic, Inc. | Porous coatings for drug release from medical devices |
JP4539974B2 (ja) | 2004-10-05 | 2010-09-08 | 日本シャーウッド株式会社 | 気管切開チューブ |
US20070299409A1 (en) * | 2004-11-09 | 2007-12-27 | Angiotech Biocoatings Corp. | Antimicrobial Needle Coating For Extended Infusion |
WO2006074177A2 (en) * | 2005-01-06 | 2006-07-13 | Mary Kay Inc. | Alcohol-free microemulsion composition |
CN101141934B (zh) * | 2005-01-14 | 2010-11-24 | 骨骼技术股份有限公司 | 可膨胀的骨植入物 |
KR100675379B1 (ko) * | 2005-01-25 | 2007-01-29 | 삼성전자주식회사 | 프린팅 시스템 및 프린팅 방법 |
EP3345632A1 (en) * | 2005-02-18 | 2018-07-11 | Abraxis BioScience, LLC | Drugs with improved hydrophobicity for incorporation in medical devices |
WO2006096518A2 (en) * | 2005-03-04 | 2006-09-14 | Neurosystec Corporation | Improved gacyclidine formulations |
US20110077579A1 (en) * | 2005-03-24 | 2011-03-31 | Harrison William V | Cochlear implant with localized fluid transport |
US8025635B2 (en) * | 2005-04-04 | 2011-09-27 | Intersect Ent, Inc. | Device and methods for treating paranasal sinus conditions |
US20060241000A1 (en) * | 2005-04-22 | 2006-10-26 | Cardiac Pacemakers, Inc. | Lubricious compound and medical device made of the same |
US20060240060A1 (en) * | 2005-04-22 | 2006-10-26 | Cardiac Pacemakers, Inc. | Lubricious compound and medical device made of the same |
US20060240059A1 (en) * | 2005-04-22 | 2006-10-26 | Cardiac Pacemakers, Inc. | Lubricious eluting polymer blend and coating made from the same |
US20060240253A1 (en) * | 2005-04-22 | 2006-10-26 | Cardiac Pacemakers, Inc. | Guidewire and tube with lubricious coating |
US8414907B2 (en) * | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
US9119901B2 (en) * | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
US9149266B2 (en) * | 2005-05-20 | 2015-10-06 | Neotract, Inc. | Deforming anchor device |
US8333776B2 (en) | 2005-05-20 | 2012-12-18 | Neotract, Inc. | Anchor delivery system |
US10925587B2 (en) | 2005-05-20 | 2021-02-23 | Neotract, Inc. | Anchor delivery system |
US7758594B2 (en) * | 2005-05-20 | 2010-07-20 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US7645286B2 (en) | 2005-05-20 | 2010-01-12 | Neotract, Inc. | Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures |
US9034001B2 (en) | 2005-05-20 | 2015-05-19 | Neotract, Inc. | Slotted anchor device |
US8668705B2 (en) | 2005-05-20 | 2014-03-11 | Neotract, Inc. | Latching anchor device |
US7909836B2 (en) | 2005-05-20 | 2011-03-22 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8394113B2 (en) | 2005-05-20 | 2013-03-12 | Neotract, Inc. | Coiled anchor device |
US8628542B2 (en) | 2005-05-20 | 2014-01-14 | Neotract, Inc. | Median lobe destruction apparatus and method |
US10195014B2 (en) | 2005-05-20 | 2019-02-05 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US8603106B2 (en) | 2005-05-20 | 2013-12-10 | Neotract, Inc. | Integrated handle assembly for anchor delivery system |
US8529584B2 (en) | 2005-05-20 | 2013-09-10 | Neotract, Inc. | Median lobe band implant apparatus and method |
US9549739B2 (en) | 2005-05-20 | 2017-01-24 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US9504461B2 (en) | 2005-05-20 | 2016-11-29 | Neotract, Inc. | Anchor delivery system |
US9364212B2 (en) | 2005-05-20 | 2016-06-14 | Neotract, Inc. | Suture anchoring devices and methods for use |
US7896891B2 (en) | 2005-05-20 | 2011-03-01 | Neotract, Inc. | Apparatus and method for manipulating or retracting tissue and anatomical structure |
US8491606B2 (en) | 2005-05-20 | 2013-07-23 | Neotract, Inc. | Median lobe retraction apparatus and method |
US8945152B2 (en) | 2005-05-20 | 2015-02-03 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8425535B2 (en) | 2005-05-20 | 2013-04-23 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8157815B2 (en) | 2005-05-20 | 2012-04-17 | Neotract, Inc. | Integrated handle assembly for anchor delivery system |
US8834492B2 (en) | 2005-05-20 | 2014-09-16 | Neotract, Inc. | Continuous indentation lateral lobe apparatus and method |
US8951225B2 (en) | 2005-06-10 | 2015-02-10 | Acclarent, Inc. | Catheters with non-removable guide members useable for treatment of sinusitis |
US8114113B2 (en) | 2005-09-23 | 2012-02-14 | Acclarent, Inc. | Multi-conduit balloon catheter |
US20070134287A1 (en) * | 2005-12-09 | 2007-06-14 | Biomet Manufacturing Corp | Method for coating biocompatible substrates with antibiotics |
US8700178B2 (en) * | 2005-12-27 | 2014-04-15 | Boston Scientific Neuromodulation Corporation | Stimulator leads and methods for lead fabrication |
US7672734B2 (en) * | 2005-12-27 | 2010-03-02 | Boston Scientific Neuromodulation Corporation | Non-linear electrode array |
FR2896165B1 (fr) * | 2006-01-13 | 2012-08-03 | Centre Nat Rech Scient | Preparation d'un substrat inorganique presentant des proprietes anti-microbiennes |
MX2008010126A (es) | 2006-02-08 | 2010-02-22 | Tyrx Pharma Inc | Protesis de malla temporalmente rigidizadas. |
US8591531B2 (en) * | 2006-02-08 | 2013-11-26 | Tyrx, Inc. | Mesh pouches for implantable medical devices |
US20070212393A1 (en) * | 2006-03-08 | 2007-09-13 | Sahajanand Medical Technologies Pvt. Ltd. | Compositions and coatings for implantable medical devices |
US8267905B2 (en) | 2006-05-01 | 2012-09-18 | Neurosystec Corporation | Apparatus and method for delivery of therapeutic and other types of agents |
US8190389B2 (en) | 2006-05-17 | 2012-05-29 | Acclarent, Inc. | Adapter for attaching electromagnetic image guidance components to a medical device |
US7803148B2 (en) | 2006-06-09 | 2010-09-28 | Neurosystec Corporation | Flow-induced delivery from a drug mass |
US20070292468A1 (en) * | 2006-06-14 | 2007-12-20 | Joel Studin | Coated jewelry articles to reduce skin irritation |
CN102258811B (zh) * | 2006-07-03 | 2015-03-11 | 汉莫堤克股份有限公司 | 持久使血管开的活性物释放医药产品的制造、方法和使用 |
US8535707B2 (en) * | 2006-07-10 | 2013-09-17 | Intersect Ent, Inc. | Devices and methods for delivering active agents to the osteomeatal complex |
US20080152694A1 (en) * | 2006-07-20 | 2008-06-26 | Neurosystec Corporation | Devices, Systems and Methods for Ophthalmic Drug Delivery |
JP2010511595A (ja) * | 2006-07-31 | 2010-04-15 | ニューロシステック コーポレイション | 遊離塩基ガシクリジンナノ粒子 |
US9820688B2 (en) | 2006-09-15 | 2017-11-21 | Acclarent, Inc. | Sinus illumination lightwire device |
US8298564B2 (en) * | 2006-09-27 | 2012-10-30 | Medtronic, Inc. | Two part antimicrobial boot |
US20080075628A1 (en) * | 2006-09-27 | 2008-03-27 | Medtronic, Inc. | Sterilized minocycline and rifampin-containing medical device |
US20080102122A1 (en) * | 2006-10-31 | 2008-05-01 | Shivkumar Mahadevan | Antimicrobial polymeric articles, processes to prepare them and methods of their use |
US9023114B2 (en) | 2006-11-06 | 2015-05-05 | Tyrx, Inc. | Resorbable pouches for implantable medical devices |
JP2010511427A (ja) * | 2006-12-01 | 2010-04-15 | ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ | コラーゲン阻害剤を含む医療デバイス |
US8439687B1 (en) | 2006-12-29 | 2013-05-14 | Acclarent, Inc. | Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices |
US20080221533A1 (en) * | 2007-03-09 | 2008-09-11 | Anthem Orthopaedics Llc | Implantable device with bioabsorbable layer, kit and method for use therewith, and apparatus for preparing same |
JP5400029B2 (ja) * | 2007-03-29 | 2014-01-29 | タイレックス・インコーポレイテッド | 乳房インプラント用生体分解性ポリマーカバー材 |
EP3766493B1 (en) | 2007-04-27 | 2023-08-23 | CyDex Pharmaceuticals, Inc. | Method for improving the stability of clopidogrel using sulfoalkyl ether cyclodextrin |
US8118757B2 (en) | 2007-04-30 | 2012-02-21 | Acclarent, Inc. | Methods and devices for ostium measurement |
US8485199B2 (en) | 2007-05-08 | 2013-07-16 | Acclarent, Inc. | Methods and devices for protecting nasal turbinate during surgery |
US8758366B2 (en) | 2007-07-09 | 2014-06-24 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
DE102007036685A1 (de) | 2007-08-03 | 2009-02-05 | Innora Gmbh | Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung |
CA2719033C (en) * | 2007-12-07 | 2014-07-08 | Zimmer Orthopaedic Surgical Products, Inc. | Spacer mold and methods therefor |
CN103961193A (zh) | 2007-12-18 | 2014-08-06 | 因特尔赛克特耳鼻喉公司 | 自扩展装置及用于其的方法 |
US10206821B2 (en) | 2007-12-20 | 2019-02-19 | Acclarent, Inc. | Eustachian tube dilation balloon with ventilation path |
US8784356B2 (en) * | 2007-12-21 | 2014-07-22 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ultrasonic endovascular clearing device |
US8444579B2 (en) * | 2007-12-21 | 2013-05-21 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System for delivering acoustic energy in connection with therapeutic ultrasound systems and catheters |
US11179298B2 (en) | 2008-01-09 | 2021-11-23 | Innovative Health Technologies, Llc | Implant pellets and methods for performing bone augmentation and preservation |
CA2715269C (en) * | 2008-02-22 | 2016-09-13 | Angiotech International Ag | Anti-infective catheters |
US8182432B2 (en) | 2008-03-10 | 2012-05-22 | Acclarent, Inc. | Corewire design and construction for medical devices |
AU2009276553B2 (en) | 2008-07-30 | 2015-02-05 | Acclarent, Inc. | Paranasal ostium finder devices and methods |
EP2345373B1 (en) | 2008-07-30 | 2020-04-29 | Neotract, Inc. | Anchor delivery system with replaceable cartridge |
US20100030052A1 (en) * | 2008-07-31 | 2010-02-04 | Bommakanti Balasubrahmanya S | Analyte sensors comprising plasticizers |
EP2320832A4 (en) | 2008-08-01 | 2015-07-29 | Intersect Ent Inc | METHODS AND DEVICES FOR CRIMPING SELF-DILATABLE DEVICES |
BRPI0919195A2 (pt) | 2008-09-18 | 2019-09-24 | Acclarent Inc | metodos e aparelhos para o tratamento de transtornos do ouvido, nariz e garganta |
AU2008363584B2 (en) * | 2008-10-29 | 2013-07-04 | Scott M. Sporer | Spacer molds with releasable securement |
BRPI0805495A2 (pt) * | 2008-12-19 | 2010-09-08 | Miranda Jose Maria De | implante de silicone com compartimentos expansìveis e/ou interativos, revestido ou não de espuma de poliuretano de ricinus communis e/ou hidroxiapatita, com abas ou cordões de fixação |
JP2010187910A (ja) * | 2009-02-18 | 2010-09-02 | Nippon Sherwood Medical Industries Ltd | 抗菌性医療用具およびその製造方法 |
US20100241155A1 (en) | 2009-03-20 | 2010-09-23 | Acclarent, Inc. | Guide system with suction |
US20100249783A1 (en) * | 2009-03-24 | 2010-09-30 | Warsaw Orthopedic, Inc. | Drug-eluting implant cover |
CN102487604A (zh) * | 2009-03-30 | 2012-06-06 | 卓银泰克医疗有限公司 | 滑液分流器 |
US8435290B2 (en) | 2009-03-31 | 2013-05-07 | Acclarent, Inc. | System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx |
US7978742B1 (en) | 2010-03-24 | 2011-07-12 | Corning Incorporated | Methods for operating diode lasers |
US9078712B2 (en) * | 2009-04-15 | 2015-07-14 | Warsaw Orthopedic, Inc. | Preformed drug-eluting device to be affixed to an anterior spinal plate |
US9414864B2 (en) | 2009-04-15 | 2016-08-16 | Warsaw Orthopedic, Inc. | Anterior spinal plate with preformed drug-eluting device affixed thereto |
WO2010129795A1 (en) * | 2009-05-08 | 2010-11-11 | 3M Innovative Properties Company | Oral care method and kit |
JP5808739B2 (ja) | 2009-05-13 | 2015-11-10 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | プラスグレル及びシクロデキストリン誘導体を含む医薬組成物並びにその製造方法及び使用方法 |
CN102573981B (zh) | 2009-05-15 | 2016-06-22 | 因特尔赛克特耳鼻喉公司 | 可展开装置及其使用方法 |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
US10045937B2 (en) * | 2009-06-03 | 2018-08-14 | Case Western Reserve University | Therapeutic agent delivery system and method |
AU2010256450B2 (en) * | 2009-06-05 | 2014-09-18 | Arthrocare Corporation | Systems and devices for providing therapy of an anatomical structure |
US8927004B1 (en) | 2014-06-11 | 2015-01-06 | Silver Bullet Therapeutics, Inc. | Bioabsorbable substrates and systems that controllably release antimicrobial metal ions |
US9114197B1 (en) | 2014-06-11 | 2015-08-25 | Silver Bullett Therapeutics, Inc. | Coatings for the controllable release of antimicrobial metal ions |
US10265435B2 (en) | 2009-08-27 | 2019-04-23 | Silver Bullet Therapeutics, Inc. | Bone implant and systems and coatings for the controllable release of antimicrobial metal ions |
EP2470257B1 (en) | 2009-08-27 | 2015-03-04 | Silver Bullet Therapeutics Inc. | Bone implants for the treatment of infection |
US9821094B2 (en) | 2014-06-11 | 2017-11-21 | Silver Bullet Therapeutics, Inc. | Coatings for the controllable release of antimicrobial metal ions |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
US8951577B2 (en) | 2010-08-03 | 2015-02-10 | Teleflex Medical Incorporated | Antimicrobial hydrochloric acid catheter lock solution and method of use |
US9155492B2 (en) | 2010-09-24 | 2015-10-13 | Acclarent, Inc. | Sinus illumination lightwire device |
EP3037066B1 (en) | 2010-11-12 | 2017-08-16 | Silver Bullet Therapeutics Inc. | Bone implant that controllably releases silver |
US8894613B2 (en) | 2011-01-22 | 2014-11-25 | Hideo Koike | Catheter attachment and method |
US9161749B2 (en) | 2011-04-14 | 2015-10-20 | Neotract, Inc. | Method and apparatus for treating sexual dysfunction |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9120040B2 (en) * | 2011-05-26 | 2015-09-01 | The University Of Akron | Anti-fouling materials based on poly(β-peptoid)s |
EP4083074A1 (en) | 2011-06-02 | 2022-11-02 | Massachusetts Institute Of Technology | Modified alginates for cell encapsulation and cell therapy |
GB2494905B (en) * | 2011-09-23 | 2013-08-14 | Cook Medical Technologies Llc | Introducer placement system |
US20130085451A1 (en) * | 2011-09-29 | 2013-04-04 | Tyco Healthcare Group Lp | Plasma-treated dialysis catheter cuff |
EP2802622A4 (en) * | 2012-01-13 | 2015-08-26 | Univ Missouri | LOW TEMPERATURE PLASMA COATING FOR ANTIBIOFILM FORMATION |
US10292801B2 (en) | 2012-03-29 | 2019-05-21 | Neotract, Inc. | System for delivering anchors for treating incontinence |
US20150072922A1 (en) * | 2012-04-17 | 2015-03-12 | The Research Institute At Nationwide Children's Hospital | Rnase 7 antimicrobial peptides |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10130353B2 (en) | 2012-06-29 | 2018-11-20 | Neotract, Inc. | Flexible system for delivering an anchor |
TWI513485B (zh) * | 2012-08-15 | 2015-12-21 | Nat Univ Tsing Hua | 微型植入裝置 |
NL2010040C2 (en) * | 2012-12-21 | 2014-06-24 | Internat Inst For Diagnostic And Analitical Affairs B V | Cleavable coating material having microbial functionality. |
US9445884B2 (en) * | 2013-01-30 | 2016-09-20 | Boston Scientific Scimed, Inc. | Ureteral stent with drug-releasing structure |
SG11201507476TA (en) | 2013-03-14 | 2015-10-29 | Intersect Ent Inc | Systems, devices, and method for treating a sinus condition |
US9433437B2 (en) | 2013-03-15 | 2016-09-06 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
WO2014144107A1 (en) | 2013-03-15 | 2014-09-18 | Hunter William L | Devices, systems and methods for monitoring hip replacements |
US9629684B2 (en) | 2013-03-15 | 2017-04-25 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
US9308137B2 (en) | 2013-03-28 | 2016-04-12 | Kimberly-Clark Worldwide, Inc. | Transitional absorbent pad and pantiliner |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
RU2530568C1 (ru) * | 2013-04-24 | 2014-10-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) | Способ изготовления внутрикостного имплантата с ионно-лучевой модификацией |
CN103301513B (zh) * | 2013-06-09 | 2015-02-04 | 诸辉 | 具有医药级酶涂层的血管支架的制备方法 |
CN105451690A (zh) | 2013-06-23 | 2016-03-30 | 威廉·L·亨特 | 用于监测膝部置换物的装置、系统及方法 |
US9579205B2 (en) | 2013-09-12 | 2017-02-28 | Ronen Shavit | Liners for medical joint implants with improved wear-resistance |
US20170176475A1 (en) * | 2014-04-11 | 2017-06-22 | Drexel University | Novel methods and kits for detecting a rifamycin, or derivative or analogue thereof |
RU2568917C1 (ru) * | 2014-04-17 | 2015-11-20 | Государственное автономное учреждение здравоохранения "Республиканская клиническая больница Министерства здравоохранения Республики Татарстан" | Способ изготовления спейсера из костного цемента |
US9452242B2 (en) | 2014-06-11 | 2016-09-27 | Silver Bullet Therapeutics, Inc. | Enhancement of antimicrobial silver, silver coatings, or silver platings |
EP3160369A4 (en) | 2014-06-25 | 2018-04-18 | Canary Medical Inc. | Devices, systems and methods for using and monitoring spinal implants |
EP3160331A4 (en) | 2014-06-25 | 2018-09-12 | Canary Medical Inc. | Devices, systems and methods for using and monitoring orthopedic hardware |
RU2558089C1 (ru) * | 2014-06-27 | 2015-07-27 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ КПССЗ" СО РАМН) | Способ предимплантационной обработки биологических протезов для сердечно-сосудистой хирургии |
CA2958820A1 (en) * | 2014-09-10 | 2016-03-17 | Double Bond Pharmaceuticals Ab | Targeted delivery of hydrophilic drugs |
SG10201902350XA (en) | 2014-09-17 | 2019-04-29 | Canary Medical Inc | Devices, systems and methods for using and monitoring medical devices |
RU2581824C1 (ru) * | 2014-11-12 | 2016-04-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) | Способ нанесения биокерамического покрытия на имплантаты |
NL2013786B1 (en) * | 2014-11-13 | 2016-10-07 | Original G B V | Quenched coating. |
CA2974376A1 (en) | 2015-01-22 | 2016-07-28 | Intersect Ent, Inc. | Drug-coated balloon |
US10471183B2 (en) | 2015-12-22 | 2019-11-12 | Access Vascular, Inc. | High strength biomedical materials |
US10433952B2 (en) | 2016-01-29 | 2019-10-08 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
EP3419682B1 (en) * | 2016-02-24 | 2024-04-03 | Innovative Surface Technologies, Inc. | Crystallization inhibitor compositions for implantable urological devices |
WO2017153052A1 (en) * | 2016-03-07 | 2017-09-14 | Double Bond Pharmaceuticals Ab | Targeted delivery of hydrophilic drugs to lung |
IL304468B1 (en) | 2016-03-23 | 2024-08-01 | Canary Medical Inc | An implantable report processor for an alert implant |
CA3027856A1 (en) | 2016-06-13 | 2017-12-21 | Massachusetts Institute Of Technology | Surface-coated continuous glucose monitors |
RU2630464C1 (ru) * | 2016-07-29 | 2017-09-08 | Федеральное государственное бюджетное научное учреждение Всероссийский научно-исследовательский институт лекарственных и ароматических растений (ФГБНУ ВИЛАР) | Комбинированный способ стерилизации костных имплантатов |
RU2626896C1 (ru) * | 2016-11-11 | 2017-08-02 | Общество с ограниченной ответственностью "ЭЛЕСТИМ-КАРДИО" | Эндокардиальная электродная система для стимуляции левых отделов сердца |
EP3541462A4 (en) | 2016-11-21 | 2020-06-17 | Neovasc Tiara Inc. | METHODS AND SYSTEMS FOR RAPID RETRACTION OF A TRANSCATHETER HEART VALVE DELIVERY SYSTEM |
KR102607919B1 (ko) * | 2017-02-09 | 2023-11-30 | 이솜 오퍼레이션스 피티와이 리미티드 | 고분자 비드 및 이의 적용 |
US11577008B2 (en) | 2017-06-21 | 2023-02-14 | Access Vascular, Inc. | High strength porous materials incorporating water soluble polymers |
US10856984B2 (en) | 2017-08-25 | 2020-12-08 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US11318231B2 (en) | 2017-11-06 | 2022-05-03 | Massachusetts Institute Of Technology | Anti-inflammatory coatings to improve biocompatibility of neurological implants |
EP4218632A1 (en) | 2017-12-23 | 2023-08-02 | Teleflex Life Sciences Limited | Expandable tissue engagement apparatus |
WO2019138412A1 (en) * | 2018-01-15 | 2019-07-18 | Technion Research & Development Foundation Limited | Electrospun-coated medical devices |
WO2019147188A1 (en) * | 2018-01-26 | 2019-08-01 | Huang ying ying | Method of selectively modifying the abluminal surface and coating the luminal surface of polymeric stent grafts |
CN108310460B (zh) * | 2018-02-02 | 2021-08-03 | 武汉大学 | 可注射高强度温敏性改性甲壳素基水凝胶及其制备方法和应用 |
CN108451553A (zh) * | 2018-03-21 | 2018-08-28 | 成都康拓邦科技有限公司 | 脑卒中手术装置及系统 |
CN108742950A (zh) * | 2018-05-11 | 2018-11-06 | 上海长海医院 | 基于健侧乳腺mri影像数据的个体化乳腺假体的制作方法 |
CN109223253A (zh) * | 2018-08-16 | 2019-01-18 | 河南科技大学第附属医院 | 一种乳房假体 |
CN113038976A (zh) * | 2018-09-06 | 2021-06-25 | 比奥莫迪克斯有限公司 | 医疗管状装置 |
AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
KR102219852B1 (ko) * | 2018-12-07 | 2021-02-25 | 주식회사 메디팹 | 중공형 케이지(hollow cage)를 포함하는 생체적합 구조체 및 이의 제조방법 |
WO2020123503A1 (en) * | 2018-12-10 | 2020-06-18 | Giridhar Thiagarajan | Antimicrobial implantable medical devices |
EP3934591A4 (en) | 2019-03-08 | 2022-11-23 | Neovasc Tiara Inc. | RETRIEVABLE PROSTHETIC RELEASE SYSTEM |
JP7438236B2 (ja) | 2019-04-01 | 2024-02-26 | ニオバスク ティアラ インコーポレイテッド | 制御可能に展開可能な補綴弁 |
CA3136334A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
CN110038159A (zh) * | 2019-04-22 | 2019-07-23 | 哈尔滨工业大学 | 柔性植入复合材料的制备方法 |
CN114025813B (zh) | 2019-05-20 | 2024-05-14 | 内奥瓦斯克迪亚拉公司 | 具有止血机构的引入器 |
CN114144144A (zh) | 2019-06-20 | 2022-03-04 | 内奥瓦斯克迪亚拉公司 | 低轮廓假体二尖瓣 |
CA3183979A1 (en) | 2020-06-30 | 2022-01-06 | Michael Bassett | Articles comprising markings and related methods |
CN117838222A (zh) | 2020-08-03 | 2024-04-09 | 泰利福生命科学有限公司 | 用于医疗干预的手柄和匣盒系统 |
WO2022067232A1 (en) * | 2020-09-28 | 2022-03-31 | Commercial Automation, Llc | Food product storage and vending kiosk |
EP4221645A1 (en) * | 2020-10-01 | 2023-08-09 | Lyra Therapeutics, Inc. | Osmotic drug delivery implants |
CN114425101B (zh) * | 2022-01-21 | 2022-07-22 | 北京大学口腔医学院 | 一种微纳米双层结构抗菌支架及其制备方法和应用 |
CN114533955B (zh) * | 2022-02-16 | 2023-07-28 | 苏州英诺科医疗科技有限公司 | 结合力强的医用镁合金表面涂层及其制备方法 |
US20230321326A1 (en) * | 2022-04-11 | 2023-10-12 | Becton, Dickinson And Company | Catheter with inherent antimicrobial properties |
PL446099A1 (pl) * | 2023-09-14 | 2024-02-12 | Politechnika Warszawska | Sposób wytwarzania bioaktywnej powłoki z kwasu foliowego na powierzchni porowatych implantów, bioaktywna powłoka wytworzona tym sposobem oraz implant z bioaktywną powłoką |
Family Cites Families (396)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US89539A (en) * | 1869-04-27 | Improvement in lighting railway-cars | ||
US259013A (en) * | 1882-06-06 | Vania | ||
US281857A (en) * | 1883-07-24 | Snap for harness | ||
US259913A (en) * | 1882-06-20 | Fourth to henry reinheimer | ||
US175323A (en) * | 1876-03-28 | Improvement in circular sawing machines | ||
US271000A (en) * | 1883-01-23 | Combination-tool for housekeepers | ||
US271024A (en) * | 1883-01-23 | Poison for squirrels | ||
US256502A (en) * | 1882-04-18 | William w | ||
US244453A (en) * | 1881-07-19 | hammeestein | ||
US45894A (en) * | 1865-01-10 | Improvement in calipers | ||
US165342A (en) * | 1875-07-06 | Improvement in potato-diggers | ||
US147491A (en) * | 1874-02-17 | Improvement in crutches | ||
US55666A (en) * | 1866-06-19 | Edwaed b | ||
US24372A (en) * | 1859-06-14 | Improvement in self-priming gun-locks | ||
US52452A (en) * | 1866-02-06 | Improvement in steam gage-cocks | ||
US216324A (en) * | 1879-06-10 | Improvement in steam-radiators | ||
US73207A (en) * | 1868-01-07 | stbele | ||
US80008A (en) * | 1868-07-14 | Isbandf | ||
US198868A (en) * | 1878-01-01 | Improvement in methods of attaching sweat-leathers to hat-bodies | ||
US1629A (en) * | 1840-06-10 | Horse-power eor driving machinery | ||
US167531A (en) * | 1875-09-07 | Improvement in dumping-wagons | ||
US255142A (en) * | 1882-03-21 | Jambs oastell | ||
US106261A (en) * | 1870-08-09 | Improvement in lubricators | ||
US244459A (en) * | 1881-07-19 | Permutation-lock | ||
US65481A (en) * | 1867-06-04 | Hen by c | ||
US65482A (en) * | 1867-06-04 | Hugh m | ||
US55053A (en) * | 1866-05-29 | Improved apparatus for lowering shipsj boats | ||
US147690A (en) * | 1874-02-17 | Improvement in belt-fastenings | ||
US42240A (en) * | 1864-04-05 | Improvement in heat-governors for stoves | ||
US63627A (en) * | 1867-04-09 | Obadiah v | ||
US195156A (en) * | 1877-09-11 | Improvement in harvester-elevators | ||
US65546A (en) * | 1867-06-11 | Improved machine foe draining sugar | ||
US216758A (en) * | 1879-06-24 | Improvement in friction-clutches | ||
US65483A (en) * | 1867-06-04 | Improvement in rotary steam engines | ||
US43052A (en) * | 1864-06-07 | photo-lithographer | ||
US276894A (en) * | 1883-05-01 | Berge | ||
DE267495C (de) | 1913-09-07 | 1913-11-20 | Max Schreiber | Sicherheitsschloss für schmucksachen |
US2819718A (en) | 1953-07-16 | 1958-01-14 | Isidore H Goldman | Drainage tube |
US3096560A (en) | 1958-11-21 | 1963-07-09 | William J Liebig | Process for synthetic vascular implants |
NL143127B (nl) | 1969-02-04 | 1974-09-16 | Rhone Poulenc Sa | Versterkingsorgaan voor een defecte hartklep. |
US3614955A (en) | 1970-02-09 | 1971-10-26 | Medtronic Inc | Standby defibrillator and method of operation |
US3614954A (en) | 1970-02-09 | 1971-10-26 | Medtronic Inc | Electronic standby defibrillator |
BE793253A (fr) | 1971-12-23 | 1973-04-16 | Lepetit Spa | Nouvelles compositions bactericides et leur utilisation |
US3945052A (en) | 1972-05-01 | 1976-03-23 | Meadox Medicals, Inc. | Synthetic vascular graft and method for manufacturing the same |
US3980650A (en) * | 1972-05-05 | 1976-09-14 | N.V. Koninklijke Pharmaceutische Fabrieken V/H Brocades-Stheeman En Pharmacia | 4-Amino-pyrimidine derivatives |
US3805301A (en) | 1972-07-28 | 1974-04-23 | Meadox Medicals Inc | Tubular grafts having indicia thereon |
DE2401619C2 (de) * | 1974-01-14 | 1986-04-03 | Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri | Fungistatisch wirksame Uracilderivate und Verfahren zu ihrer Herstellung |
GB1527592A (en) | 1974-08-05 | 1978-10-04 | Ici Ltd | Wound dressing |
US3995623A (en) | 1974-12-23 | 1976-12-07 | American Hospital Supply Corporation | Multipurpose flow-directed catheter |
US4281669A (en) | 1975-05-09 | 1981-08-04 | Macgregor David C | Pacemaker electrode with porous system |
US4033962A (en) * | 1975-06-26 | 1977-07-05 | Hoffman-La Roche Inc. | 2,4-Diamino-pyrimidine derivatives and processes |
US4096860A (en) | 1975-10-08 | 1978-06-27 | Mclaughlin William F | Dual flow encatheter |
JPS5289680A (en) | 1976-01-22 | 1977-07-27 | Mitsui Toatsu Chem Inc | Preparation of 1-(2-tetrahydrofuryl)-5-flurouracil |
CA1069652A (en) | 1976-01-09 | 1980-01-15 | Alain F. Carpentier | Supported bioprosthetic heart valve with compliant orifice ring |
US4134402A (en) | 1976-02-11 | 1979-01-16 | Mahurkar Sakharam D | Double lumen hemodialysis catheter |
GB1546937A (en) | 1976-07-29 | 1979-05-31 | Beecham Group Ltd | 2,4-diaminopyrimidine derivatives |
US4072146A (en) | 1976-09-08 | 1978-02-07 | Howes Randolph M | Venous catheter device |
US4335723A (en) | 1976-11-26 | 1982-06-22 | The Kendall Company | Catheter having inflatable retention means |
US4099528A (en) | 1977-02-17 | 1978-07-11 | Sorenson Research Co., Inc. | Double lumen cannula |
US4140126A (en) | 1977-02-18 | 1979-02-20 | Choudhury M Hasan | Method for performing aneurysm repair |
JPS53149985A (en) | 1977-05-31 | 1978-12-27 | Asahi Chem Ind Co Ltd | Preparation of 5-fluorouracil derivatives |
US4180068A (en) | 1978-04-13 | 1979-12-25 | Motion Control, Incorporated | Bi-directional flow catheter with retractable trocar/valve structure |
EP0005035B1 (en) | 1978-04-19 | 1981-09-23 | Imperial Chemical Industries Plc | A method of preparing a tubular product by electrostatic spinning |
SE7903361L (sv) | 1978-04-20 | 1979-10-21 | Johnson Matthey Co Ltd | Kompositioner innehallande platina |
US4215062A (en) * | 1978-05-22 | 1980-07-29 | University Of Kansas Endowment Association | Anthracycline synthesis |
US4284459A (en) | 1978-07-03 | 1981-08-18 | The Kendall Company | Method for making a molded catheter |
US4296105A (en) | 1978-08-03 | 1981-10-20 | Institut International De Pathologie Cellulaire Et Moleculaire | Derivatives of doxorubicine, their preparation and use |
JPS5559173A (en) | 1978-10-27 | 1980-05-02 | Kaken Pharmaceut Co Ltd | Novel fluorouracil derivative |
US4227533A (en) | 1978-11-03 | 1980-10-14 | Bristol-Myers Company | Flushable urinary catheter |
US4375817A (en) | 1979-07-19 | 1983-03-08 | Medtronic, Inc. | Implantable cardioverter |
DE3010841A1 (de) | 1980-03-21 | 1981-10-08 | Ulrich Dr.med. 6936 Haag Uthmann | Katheder |
US4299778A (en) | 1980-07-21 | 1981-11-10 | Shell Oil Company | N'Cyclopropyl-N-(fluorophenyl)-N-hydroxyureas |
US4301277A (en) | 1980-10-20 | 1981-11-17 | Sri International | 3-Deamino-3-(4-morpholinyl) derivatives of daunorubicin and doxorubicin |
US4314054A (en) | 1981-03-23 | 1982-02-02 | Sri International | 3'-Deamino-3'-(4-methoxy-1-piperidinyl) derivatives of daunorubicin and doxorubicin |
US4406656A (en) | 1981-06-01 | 1983-09-27 | Brack Gillium Hattler | Venous catheter having collapsible multi-lumens |
US4534899A (en) | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
US4475972A (en) | 1981-10-01 | 1984-10-09 | Ontario Research Foundation | Implantable material |
US4568329A (en) | 1982-03-08 | 1986-02-04 | Mahurkar Sakharam D | Double lumen catheter |
US4546499A (en) | 1982-12-13 | 1985-10-15 | Possis Medical, Inc. | Method of supplying blood to blood receiving vessels |
EP0117485A3 (de) | 1983-02-28 | 1985-01-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyridin-, Pyrazin- und Pyrimidinderivate und deren Verwendung als fungizide Wirkstoffe |
US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
CA1244028A (en) * | 1983-04-14 | 1988-11-01 | Hans Maag | Pyrimidine derivatives |
US4530113A (en) | 1983-05-20 | 1985-07-23 | Intervascular, Inc. | Vascular grafts with cross-weave patterns |
US4585859A (en) | 1983-05-24 | 1986-04-29 | Sri International | Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin |
DE3323025A1 (de) * | 1983-06-25 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
JPS6019789A (ja) * | 1983-07-12 | 1985-01-31 | Kyorin Pharmaceut Co Ltd | イミダゾ〔1,5−a〕ピリミジン誘導体 |
GB8319766D0 (en) * | 1983-07-22 | 1983-08-24 | Graham N B | Controlled release device |
US4550447A (en) | 1983-08-03 | 1985-11-05 | Shiley Incorporated | Vascular graft prosthesis |
US4647416A (en) | 1983-08-03 | 1987-03-03 | Shiley Incorporated | Method of preparing a vascular graft prosthesis |
US4490529A (en) | 1983-09-06 | 1984-12-25 | Dana-Farber Cancer Institute, Inc. | Cysteic acid and homocysteic acid analogues of methotrexate and aminopterin |
US5104399A (en) | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
US4500676A (en) * | 1983-12-15 | 1985-02-19 | Biomatrix, Inc. | Hyaluronate modified polymeric articles |
US4571241A (en) | 1983-12-16 | 1986-02-18 | Christopher T Graham | Urinary catheter with collapsible urethral tube |
US4710169A (en) | 1983-12-16 | 1987-12-01 | Christopher T Graham | Urinary catheter with collapsible urethral tube |
US5197977A (en) | 1984-01-30 | 1993-03-30 | Meadox Medicals, Inc. | Drug delivery collagen-impregnated synthetic vascular graft |
US4562596A (en) | 1984-04-25 | 1986-01-07 | Elliot Kornberg | Aortic graft, device and method for performing an intraluminal abdominal aortic aneurysm repair |
US4891225A (en) * | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
US4782836A (en) | 1984-05-24 | 1988-11-08 | Intermedics, Inc. | Rate adaptive cardiac pacemaker responsive to patient activity and temperature |
US5266563A (en) | 1984-06-11 | 1993-11-30 | Biomatrix, Inc. | Hyakyribate-poly (ethylene oxide) mixtures |
US4629623A (en) | 1984-06-11 | 1986-12-16 | Biomatrix, Inc. | Hyaluronate-poly (ethylene oxide) compositions and cosmetic formulations thereof |
JPS6143191A (ja) | 1984-08-07 | 1986-03-01 | Kyorin Pharmaceut Co Ltd | イミダゾ〔1,5−a〕ピリミジン誘導体 |
US4588831A (en) | 1984-11-09 | 1986-05-13 | Natec | Platinum complex compounds of substituted 5,8-dihydroxyl-1,4-naphthoquinone, and process for their production and use |
US4582865A (en) | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
US4636524A (en) | 1984-12-06 | 1987-01-13 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
US5128326A (en) | 1984-12-06 | 1992-07-07 | Biomatrix, Inc. | Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same |
US4662382A (en) | 1985-01-16 | 1987-05-05 | Intermedics, Inc. | Pacemaker lead with enhanced sensitivity |
US4860751A (en) | 1985-02-04 | 1989-08-29 | Cordis Corporation | Activity sensor for pacemaker control |
US4713448A (en) | 1985-03-12 | 1987-12-15 | Biomatrix, Inc. | Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues |
US5099013A (en) | 1985-03-12 | 1992-03-24 | Biomatrix, Inc, | Hylan preparation and method of recovery thereof from animal tissues |
US4714703A (en) * | 1985-09-11 | 1987-12-22 | Burckhalter Joseph H | Method of inhibiting herpetic lesions |
US4701162A (en) | 1985-09-24 | 1987-10-20 | The Kendall Company | Foley catheter assembly |
DE3780374D1 (de) | 1986-07-31 | 1992-08-20 | Irnich Werner | Frequenzadaptierender herzschrittmacher. |
US4882168A (en) | 1986-09-05 | 1989-11-21 | American Cyanamid Company | Polyesters containing alkylene oxide blocks as drug delivery systems |
US4960409A (en) | 1986-09-11 | 1990-10-02 | Catalano Marc L | Method of using bilumen peripheral venous catheter with adapter |
US5004606A (en) | 1986-09-24 | 1991-04-02 | Hybritech Incorporated | Non-covalent antibody-anthracycline immunocomplexes |
JPS63112530A (ja) * | 1986-10-29 | 1988-05-17 | Kyushu Kogyo Univ | 1,4,5,8−テトラメトキシナフタレンの製造法 |
GB8701381D0 (en) | 1987-01-22 | 1987-02-25 | Erba Farmitalia | Antitumor agent |
FR2611203B1 (fr) | 1987-02-20 | 1989-06-09 | Sturtz Georges | Analogues gem-diphosphoniques d'amethopterine (methotrexate) et de derives deaza-n-10 amethopterine. leur preparation et les compositions pharmaceutiques qui les contiennent |
US4913743A (en) | 1987-04-15 | 1990-04-03 | Biomatrix, Inc. | Processes for managing keratinous material using glycosaminoglycan and cationic polymer combinations |
US4795741A (en) | 1987-05-06 | 1989-01-03 | Biomatrix, Inc. | Compositions for therapeutic percutaneous embolization and the use thereof |
CA1330285C (en) | 1987-12-22 | 1994-06-21 | Geoffrey S. Martin | Triple lumen catheter |
US5019096A (en) * | 1988-02-11 | 1991-05-28 | Trustees Of Columbia University In The City Of New York | Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same |
US5059186A (en) | 1988-03-07 | 1991-10-22 | Vitaphore Corporation | Percutaneous access device |
US4892540A (en) | 1988-04-21 | 1990-01-09 | Sorin Biomedica S.P.A. | Two-leaflet prosthetic heart valve |
GB8820945D0 (en) * | 1988-09-07 | 1988-10-05 | Smith & Nephew | Medical articles |
US5176661A (en) | 1988-09-06 | 1993-01-05 | Advanced Cardiovascular Systems, Inc. | Composite vascular catheter |
US5024671A (en) | 1988-09-19 | 1991-06-18 | Baxter International Inc. | Microporous vascular graft |
US5066658A (en) | 1988-11-10 | 1991-11-19 | Ortho Pharmaceutical Corporation | Substituted hydroxyureas |
US5165952A (en) * | 1989-01-18 | 1992-11-24 | Becton, Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
US4999210A (en) * | 1989-01-18 | 1991-03-12 | Becton, Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
IE64997B1 (en) * | 1989-01-18 | 1995-10-04 | Becton Dickinson Co | Anti-infection and antithrombogenic medical articles and method for their preparation |
US6261271B1 (en) | 1989-01-18 | 2001-07-17 | Becton Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
US5013306A (en) * | 1989-01-18 | 1991-05-07 | Becton, Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
US4925668A (en) * | 1989-01-18 | 1990-05-15 | Becton, Dickinson And Company | Anti-infective and lubricious medical articles and method for their preparation |
US5041100A (en) * | 1989-04-28 | 1991-08-20 | Cordis Corporation | Catheter and hydrophilic, friction-reducing coating thereon |
US5015238A (en) * | 1989-06-21 | 1991-05-14 | Becton, Dickinson And Company | Expandable obturator and catheter assembly including same |
US5242073A (en) | 1989-08-23 | 1993-09-07 | Aluminum Company Of America | Resealable container closure |
US5166149A (en) | 1989-09-08 | 1992-11-24 | Chemex Pharmaceuticals, Inc. | Methotrexate compositions and methods of treatment using same |
DE69029735T2 (de) | 1989-09-15 | 1997-07-31 | Chiron Vision Corp., Irvine, Calif. | Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse |
US5064415A (en) | 1989-10-26 | 1991-11-12 | Becton, Dickinson And Company | Catheter obturator with automatic feed and control |
US4976697A (en) | 1989-10-26 | 1990-12-11 | Becton, Dickinson And Company | Catheter obturator with automatic feed and control |
US5153174A (en) | 1989-10-30 | 1992-10-06 | Union Carbide Chemicals & Plastics Inc. | Polymer mixtures useful in skin care |
US5525348A (en) * | 1989-11-02 | 1996-06-11 | Sts Biopolymers, Inc. | Coating compositions comprising pharmaceutical agents |
US5069899A (en) | 1989-11-02 | 1991-12-03 | Sterilization Technical Services, Inc. | Anti-thrombogenic, anti-microbial compositions containing heparin |
DK0434960T3 (da) | 1989-12-19 | 1996-10-14 | Pharmacia Spa | Chirale 1,5-diiod-2-methoxy- eller benzyloxymellemprodukter |
US5101824A (en) | 1990-04-16 | 1992-04-07 | Siemens-Pacesetter, Inc. | Rate-responsive pacemaker with circuitry for processing multiple sensor inputs |
GB2243838A (en) * | 1990-05-09 | 1991-11-13 | Learonal | Process for metallising a through-hole printed circuit board by electroplating |
US5407683A (en) | 1990-06-01 | 1995-04-18 | Research Corporation Technologies, Inc. | Pharmaceutical solutions and emulsions containing taxol |
US5833665A (en) * | 1990-06-14 | 1998-11-10 | Integra Lifesciences I, Ltd. | Polyurethane-biopolymer composite |
US5594158A (en) | 1990-06-22 | 1997-01-14 | The Board Of Regents Of The University Of Nebraska | Processes for producing doxorubicin, daunomycinone, and derivatives of doxorubicin |
US5246698A (en) | 1990-07-09 | 1993-09-21 | Biomatrix, Inc. | Biocompatible viscoelastic gel slurries, their preparation and use |
US5130126A (en) * | 1990-07-09 | 1992-07-14 | Nippon Oil & Fats Co., Ltd. | Polymer-drug conjugate and a method of producing it |
US5143724A (en) | 1990-07-09 | 1992-09-01 | Biomatrix, Inc. | Biocompatible viscoelastic gel slurries, their preparation and use |
US5405379A (en) | 1990-07-26 | 1995-04-11 | Lane; Rodney J. | Self expanding vascular endoprosthesis for aneurysms |
KR100234870B1 (ko) | 1990-08-23 | 1999-12-15 | 로버트 피. 블랙번 | 제조합 콜로니 자극인자-1을 함유하는 약제학적 조성물 |
PH31064A (en) * | 1990-09-07 | 1998-02-05 | Nycomed As Of Nycoveten | Polymers containing diester units. |
CA2052981C (en) | 1990-10-09 | 1995-08-01 | Cesare Gianturco | Percutaneous stent assembly |
WO1992006701A1 (en) * | 1990-10-18 | 1992-04-30 | Huffstutler, M., Conrad, Jr. | Preparation of concentrated fluid symphytum extracts, therapeutic forms and methods of use |
US5207648A (en) * | 1990-12-14 | 1993-05-04 | The Kendall Company | Multilumen catheter |
DE59008908D1 (de) | 1990-12-19 | 1995-05-18 | Osypka Peter | Herzschrittmacherleitung mit einem inneren Kanal und mit einem Elektrodenkopf. |
US5116360A (en) | 1990-12-27 | 1992-05-26 | Corvita Corporation | Mesh composite graft |
US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US6387052B1 (en) | 1991-01-29 | 2002-05-14 | Edwards Lifesciences Corporation | Thermodilution catheter having a safe, flexible heating element |
US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
AU1579092A (en) * | 1991-02-27 | 1992-10-06 | Nova Pharmaceutical Corporation | Anti-infective and anti-inflammatory releasing systems for medical devices |
US5520664A (en) * | 1991-03-01 | 1996-05-28 | Spire Corporation | Catheter having a long-lasting antimicrobial surface treatment |
US5405363A (en) | 1991-03-15 | 1995-04-11 | Angelon Corporation | Implantable cardioverter defibrillator having a smaller displacement volume |
US5939420A (en) * | 1991-04-08 | 1999-08-17 | Duquesne University Of The Holy Ghost | Pyrrolo 2,3d!derivatives |
FR2678833B1 (fr) | 1991-07-08 | 1995-04-07 | Rhone Poulenc Rorer Sa | Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes. |
US5238926A (en) * | 1991-08-20 | 1993-08-24 | Schering Corporation | Anti-fungal agents |
US5346898A (en) * | 1992-06-18 | 1994-09-13 | Schering Corporation | Anti-fungal uracil compounds |
US5151105A (en) | 1991-10-07 | 1992-09-29 | Kwan Gett Clifford | Collapsible vessel sleeve implant |
AU675211B2 (en) | 1991-10-16 | 1997-01-30 | Richardson-Vicks Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
FR2683529B1 (fr) | 1991-11-12 | 1994-02-04 | Bretagne Occidentale Universite | Composes pharmaceutiques gem-diphosphonates analogues du cis-platine. |
WO1993010847A1 (en) | 1991-12-06 | 1993-06-10 | North Shore University Hospital Research Corporation | Method of reducing medical device related infections |
US5221256A (en) * | 1992-02-10 | 1993-06-22 | Mahurkar Sakharam D | Multiple-lumen catheter |
US5284491A (en) | 1992-02-27 | 1994-02-08 | Medtronic, Inc. | Cardiac pacemaker with hysteresis behavior |
US5301664A (en) | 1992-03-06 | 1994-04-12 | Sievers Robert E | Methods and apparatus for drug delivery using supercritical solutions |
GB9204918D0 (en) | 1992-03-06 | 1992-04-22 | Nycomed As | Chemical compounds |
EP0706373B1 (en) | 1992-03-23 | 2000-07-19 | Georgetown University | Liposome encapsulated taxol and a method of using the same |
US5461223A (en) | 1992-10-09 | 1995-10-24 | Eastman Kodak Company | Bar code detecting circuitry |
US5552156A (en) | 1992-10-23 | 1996-09-03 | Ohio State University | Liposomal and micellular stabilization of camptothecin drugs |
US5322520A (en) * | 1992-11-12 | 1994-06-21 | Implemed, Inc. | Iontophoretic structure for medical devices |
US6287484B1 (en) | 1992-11-12 | 2001-09-11 | Robert Hausslein | Iontophoretic material |
US5300022A (en) | 1992-11-12 | 1994-04-05 | Martin Klapper | Urinary catheter and bladder irrigation system |
US6060000A (en) * | 1992-11-12 | 2000-05-09 | Implemed, Inc. | Iontophoretic material containing carbon and metal granules |
US5496362A (en) | 1992-11-24 | 1996-03-05 | Cardiac Pacemakers, Inc. | Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation |
FR2698543B1 (fr) | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
US5716395A (en) | 1992-12-11 | 1998-02-10 | W.L. Gore & Associates, Inc. | Prosthetic vascular graft |
US5439686A (en) | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
US5697953A (en) | 1993-03-13 | 1997-12-16 | Angeion Corporation | Implantable cardioverter defibrillator having a smaller displacement volume |
US5382582A (en) | 1993-03-26 | 1995-01-17 | Chan; Carcy L. | Methotrexate analogs and methods of using same |
AU6833994A (en) | 1993-05-17 | 1994-12-12 | Liposome Company, Inc., The | Incorporation of taxol into liposomes and gels |
US5380897A (en) | 1993-05-25 | 1995-01-10 | Hoeschele; James D. | Tri(platinum) complexes |
US5314430A (en) | 1993-06-24 | 1994-05-24 | Medtronic, Inc. | Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use |
JPH0767895A (ja) | 1993-06-25 | 1995-03-14 | Sumitomo Electric Ind Ltd | 抗菌性人工血管及び抗菌性手術用縫合糸 |
US5886026A (en) * | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
KR101222904B1 (ko) * | 1993-07-19 | 2013-01-17 | 안지오테크 파마슈티칼즈, 인코포레이티드 | 항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법 |
US20030203976A1 (en) * | 1993-07-19 | 2003-10-30 | William L. Hunter | Anti-angiogenic compositions and methods of use |
ES2139746T3 (es) | 1993-07-20 | 2000-02-16 | Pfizer | Heteroaril cicloalquenil hidroxiureas. |
JPH0763933A (ja) * | 1993-08-25 | 1995-03-10 | Ricoh Co Ltd | 光集積回路 |
US5409915A (en) | 1993-09-14 | 1995-04-25 | The University Of Vermont And State Agricultural College | Bis-platinum (IV) complexes as chemotherapeutic agents |
US5609624A (en) | 1993-10-08 | 1997-03-11 | Impra, Inc. | Reinforced vascular graft and method of making same |
US6361526B1 (en) * | 1993-11-01 | 2002-03-26 | Medtronic Xomed, Inc. | Antimicrobial tympanostomy tube |
WO1995013033A1 (en) | 1993-11-08 | 1995-05-18 | Lazarus Harrison M | Intraluminal vascular graft and method |
JPH09507214A (ja) | 1993-12-08 | 1997-07-22 | ビタフォア コーポレイション | マイクロスフェアー ドラッグ デリバリー システム |
US5752941A (en) * | 1994-02-15 | 1998-05-19 | Gruppo Lepetit S.P.A. | Central venous catheters loaded with antibiotics of the ramoplanin group preventing development of catheter related infections |
US5534499A (en) | 1994-05-19 | 1996-07-09 | The University Of British Columbia | Lipophilic drug derivatives for use in liposomes |
US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5562652A (en) * | 1994-10-07 | 1996-10-08 | Davis; William M. | Antiseptic medical apparatus |
US5554106A (en) * | 1994-10-13 | 1996-09-10 | Quinton Instrument Company | Hydrocolloid exit site dressing |
US5569207A (en) | 1994-10-13 | 1996-10-29 | Quinton Instrument Company | Hydrocolloid dressing |
US5620419A (en) * | 1994-10-14 | 1997-04-15 | Cook Pacemaker Corporation | Port stabilizer ring |
US6063396A (en) * | 1994-10-26 | 2000-05-16 | Houston Biotechnology Incorporated | Methods and compositions for the modulation of cell proliferation and wound healing |
US5869127A (en) | 1995-02-22 | 1999-02-09 | Boston Scientific Corporation | Method of providing a substrate with a bio-active/biocompatible coating |
US6179817B1 (en) * | 1995-02-22 | 2001-01-30 | Boston Scientific Corporation | Hybrid coating for medical devices |
US6468649B1 (en) | 1995-02-22 | 2002-10-22 | Scimed Life Systems, Inc. | Antimicrobial adhesion surface |
GB9506769D0 (en) * | 1995-03-28 | 1995-05-24 | Aortech Europ Ltd | Device |
US5627187A (en) * | 1995-04-12 | 1997-05-06 | Katz; Bruce E. | 5-FU for treating actinic kerotoses |
US5624704A (en) | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
US5772694A (en) | 1995-05-16 | 1998-06-30 | Medical Carbon Research Institute L.L.C. | Prosthetic heart valve with improved blood flow |
US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
US5609629A (en) | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
AU716005B2 (en) * | 1995-06-07 | 2000-02-17 | Cook Medical Technologies Llc | Implantable medical device |
EP0753523A1 (en) | 1995-07-10 | 1997-01-15 | Gador S.A. | Amino-substituted bisphosphonic acids |
US5607385A (en) | 1995-08-17 | 1997-03-04 | Medtronic, Inc. | Device and algorithm for a combined cardiomyostimulator and a cardiac pacer-carioverter-defibrillator |
FR2740978B1 (fr) | 1995-11-10 | 1998-01-02 | Ela Medical Sa | Dispositif medical actif du type defibrillateur/cardioverteur implantable |
US5709672A (en) * | 1995-11-01 | 1998-01-20 | Texas Tech University Health Sciences Center | Silastic and polymer-based catheters with improved antimicrobial/antifungal properties |
CA2189097A1 (en) * | 1995-11-15 | 1997-05-16 | Pin-Fang Lin | Composition and method of treating retroviral infection |
US5843903A (en) | 1995-11-27 | 1998-12-01 | The Administrators Of The Tulane Educational Fund | Targeted cytotoxic anthracycline analogs |
CA2171073A1 (en) | 1995-12-04 | 1997-06-05 | Philip C. Lang | Process for the preparation of ethyl-n-(2,3 dichloro-6- nitrobenzyl) glycine |
JPH09319097A (ja) * | 1996-01-16 | 1997-12-12 | Sumitomo Chem Co Ltd | レジストパターンの形成方法 |
JP4341986B2 (ja) * | 1996-02-15 | 2009-10-14 | インターフェイス バイオロジックス インコーポレイテッド | 生体応答性、薬理学的活性重合体及びこれから製造された物品 |
US5861191A (en) * | 1996-02-26 | 1999-01-19 | Technology Licensing Company | Bacteriostatic coating of polymeric conduit |
US5951588A (en) * | 1996-02-29 | 1999-09-14 | Moenning; Stephen P. | Apparatus and method for protecting a port site opening in the wall of a body cavity |
US5766220A (en) * | 1996-02-29 | 1998-06-16 | Moenning; Stephen P. | Apparatus and method for protecting a port site opening in the wall of a body cavity |
US5942555A (en) | 1996-03-21 | 1999-08-24 | Surmodics, Inc. | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom |
US6132765A (en) * | 1996-04-12 | 2000-10-17 | Uroteq Inc. | Drug delivery via therapeutic hydrogels |
US5759564A (en) * | 1996-04-16 | 1998-06-02 | Implemed, Inc. | Iontophoretic material |
US5741224A (en) * | 1996-04-16 | 1998-04-21 | Implemed, Inc. | Iontophoretic material |
US6117125A (en) * | 1996-05-02 | 2000-09-12 | Cook Incorporated | Method for predetermining uniform flow rate of a fluid from a tubular body and device therefrom |
US6419673B1 (en) * | 1996-05-06 | 2002-07-16 | Stuart Edwards | Ablation of rectal and other internal body structures |
US5921954A (en) * | 1996-07-10 | 1999-07-13 | Mohr, Jr.; Lawrence G. | Treating aneurysms by applying hardening/softening agents to hardenable/softenable substances |
US5741779A (en) | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
AU716764B2 (en) * | 1996-06-04 | 2000-03-09 | Cook Incorporated | Implantable medical device |
US5913848A (en) | 1996-06-06 | 1999-06-22 | Luther Medical Products, Inc. | Hard tip over-the-needle catheter and method of manufacturing the same |
US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
CA2266478C (en) | 1996-09-23 | 2002-11-12 | Focal, Inc. | Polymerizable biodegradable polymers including carbonate or dioxanone linkages |
US5895419A (en) * | 1996-09-30 | 1999-04-20 | St. Jude Medical, Inc. | Coated prosthetic cardiac device |
US5800412A (en) | 1996-10-10 | 1998-09-01 | Sts Biopolymers, Inc. | Hydrophilic coatings with hydrating agents |
US6530951B1 (en) * | 1996-10-24 | 2003-03-11 | Cook Incorporated | Silver implantable medical device |
ATE279213T1 (de) | 1996-11-06 | 2004-10-15 | Sts Biopolymers Inc | Beschichtung mit gasenthaltenden hohlräumen zur verstärkung von ultraschall-echos |
US7229413B2 (en) | 1996-11-06 | 2007-06-12 | Angiotech Biocoatings Corp. | Echogenic coatings with overcoat |
US6106473A (en) | 1996-11-06 | 2000-08-22 | Sts Biopolymers, Inc. | Echogenic coatings |
US5783689A (en) * | 1996-11-12 | 1998-07-21 | University Of Notre Dame | Antibacterial and antifungal nucleosides |
US5877263A (en) * | 1996-11-25 | 1999-03-02 | Meadox Medicals, Inc. | Process for preparing polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents |
EP1018982B1 (en) * | 1996-12-03 | 2005-03-09 | Osteobiologics, Inc. | Biodegradable polymeric film |
US6458373B1 (en) | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
US5997517A (en) | 1997-01-27 | 1999-12-07 | Sts Biopolymers, Inc. | Bonding layers for medical device surface coatings |
US5827533A (en) | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
DE69832288T2 (de) | 1997-03-20 | 2006-07-13 | Genzyme Corp., Cambridge | Biologisch abbaubarer gewebespreizer |
US6065645A (en) | 1997-04-01 | 2000-05-23 | Discus Dental Impressions, Inc. | Double-barreled syringe with detachable locking mixing tip |
ATE279461T1 (de) | 1997-04-03 | 2004-10-15 | Guilford Pharm Inc | Bioabbaubare terephthalat polyester-polyphosphat polymere, zusammensetzungen, gegenstände und verfahren für ihre herstellung und verwendung |
UA54505C2 (ru) | 1997-04-03 | 2003-03-17 | Гілфорд Фармасьютікалз Інк. | Биологически разлагаемые полимеры, сшитые фосфатами, составы, изделия и способы для их изготовления и использования |
US5912225A (en) * | 1997-04-14 | 1999-06-15 | Johns Hopkins Univ. School Of Medicine | Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same |
KR20010020432A (ko) * | 1997-04-30 | 2001-03-15 | 토마스 씨. 서 | 폴리(고리지방족 포스포에스테르) 화합물로 이루어진 생분해성 조성물, 약품 및 그의 이용방법 |
US5879697A (en) * | 1997-04-30 | 1999-03-09 | Schneider Usa Inc | Drug-releasing coatings for medical devices |
DE19718430A1 (de) * | 1997-04-30 | 1999-01-14 | Stemberger Axel Dr | Behandlung von Biomaterial |
JPH10328293A (ja) * | 1997-06-04 | 1998-12-15 | Unitika Ltd | 医療用具及びその製造方法 |
AU7972498A (en) | 1997-06-18 | 1999-01-04 | Boston Scientific Corporation | Polycarbonate-polyurethane dispersions for thrombo-resistant coatings |
US6110483A (en) | 1997-06-23 | 2000-08-29 | Sts Biopolymers, Inc. | Adherent, flexible hydrogel and medicated coatings |
US5921965A (en) * | 1997-07-07 | 1999-07-13 | New York University | Tubing device for antibiotic administration through central venous catheters |
ZA987019B (en) | 1997-08-06 | 1999-06-04 | Focal Inc | Hemostatic tissue sealants |
US6067471A (en) | 1998-08-07 | 2000-05-23 | Cardiac Pacemakers, Inc. | Atrial and ventricular implantable cardioverter-defibrillator and lead system |
US6306166B1 (en) * | 1997-08-13 | 2001-10-23 | Scimed Life Systems, Inc. | Loading and release of water-insoluble drugs |
US6121027A (en) | 1997-08-15 | 2000-09-19 | Surmodics, Inc. | Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups |
US5854382A (en) * | 1997-08-18 | 1998-12-29 | Meadox Medicals, Inc. | Bioresorbable compositions for implantable prostheses |
US6316522B1 (en) * | 1997-08-18 | 2001-11-13 | Scimed Life Systems, Inc. | Bioresorbable hydrogel compositions for implantable prostheses |
US6197785B1 (en) * | 1997-09-03 | 2001-03-06 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
US6080874A (en) | 1997-09-25 | 2000-06-27 | Abbott Laboratories | Synthesis and isolation of N-(aryl or heteroaryl)-alkyl-N-hydroxyurea |
US6149574A (en) | 1997-12-19 | 2000-11-21 | Radiance Medical Systems, Inc. | Dual catheter radiation delivery system |
WO1999035162A1 (en) | 1998-01-07 | 1999-07-15 | Jenner Biotherapies, Inc. | Therapeutic liposome-encapsulated immunomodulators |
US6096075A (en) | 1998-01-22 | 2000-08-01 | Medical Carbon Research Institute, Llc | Prosthetic heart valve |
US6340757B1 (en) | 1998-03-06 | 2002-01-22 | Ube Industries, Ltd. | 6-(1-fluoroalkyl)-4-pyrimidones and processes for producing the same |
US6007833A (en) | 1998-03-19 | 1999-12-28 | Surmodics, Inc. | Crosslinkable macromers bearing initiator groups |
US6176877B1 (en) | 1998-04-20 | 2001-01-23 | St. Jude Medical, Inc. | Two piece prosthetic heart valve |
AU760408B2 (en) * | 1998-04-27 | 2003-05-15 | Surmodics, Inc. | Bioactive agent release coating |
US6200598B1 (en) | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
US6146659A (en) | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
US6055454A (en) | 1998-07-27 | 2000-04-25 | Cardiac Pacemakers, Inc. | Cardiac pacemaker with automatic response optimization of a physiologic sensor based on a second sensor |
US6152943A (en) | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
US6514534B1 (en) | 1998-08-14 | 2003-02-04 | Incept Llc | Methods for forming regional tissue adherent barriers and drug delivery systems |
US6273875B1 (en) * | 1998-08-17 | 2001-08-14 | Edwards Lifesciences Corporation | Medical devices having improved antimicrobial/antithrombogenic properties |
CA2340652C (en) | 1998-08-20 | 2013-09-24 | Cook Incorporated | Coated implantable medical device comprising paclitaxel |
US6335029B1 (en) * | 1998-08-28 | 2002-01-01 | Scimed Life Systems, Inc. | Polymeric coatings for controlled delivery of active agents |
US20050147690A1 (en) | 1998-09-25 | 2005-07-07 | Masters David B. | Biocompatible protein particles, particle devices and methods thereof |
US6153212A (en) | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
WO2000030698A1 (en) | 1998-11-20 | 2000-06-02 | University Of Connecticut | Apparatus and method for control of tissue/implant interactions |
US6409764B1 (en) * | 1998-12-03 | 2002-06-25 | Charles F. White | Methods and articles for regenerating bone or peridontal tissue |
JP2002531217A (ja) | 1998-12-04 | 2002-09-24 | チャンドラシェカー ピー. パサック, | 生体適合性架橋ポリマー |
AU2042200A (en) | 1998-12-07 | 2000-06-26 | Baylor College Of Medicine | Preventing and removing biofilm from the surface of medical devices |
EP1188750B1 (de) * | 1998-12-21 | 2003-10-15 | Lonza AG | Verfahren zur Herstellung von 2,5-Diamino-4,6-dihalogenpyrimidinen |
US20020065546A1 (en) * | 1998-12-31 | 2002-05-30 | Machan Lindsay S. | Stent grafts with bioactive coatings |
UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
US6566419B2 (en) * | 1999-02-25 | 2003-05-20 | Seefar Technologies, Inc. | Degradable plastics possessing a microbe-inhibiting quality |
WO2000053231A2 (en) | 1999-03-09 | 2000-09-14 | Protarga, Inc. | Fatty acid-anticancer conjugates and uses thereof |
US6409723B1 (en) * | 1999-04-02 | 2002-06-25 | Stuart D. Edwards | Treating body tissue by applying energy and substances |
US6340465B1 (en) * | 1999-04-12 | 2002-01-22 | Edwards Lifesciences Corp. | Lubricious coatings for medical devices |
US6169923B1 (en) | 1999-04-23 | 2001-01-02 | Pacesetter, Inc. | Implantable cardioverter-defibrillator with automatic arrhythmia detection criteria adjustment |
BR0010794A (pt) | 1999-05-24 | 2002-06-04 | Sonus Pharma Inc | Emulsão-veìculo para drogas com fraca solubilidade |
US6425853B1 (en) * | 1999-06-23 | 2002-07-30 | Stuart D. Edwards | Treating body tissue by applying energy and substances with a retractable catheter and contained cooling element |
US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
US6309660B1 (en) | 1999-07-28 | 2001-10-30 | Edwards Lifesciences Corp. | Universal biocompatible coating platform for medical devices |
US6368611B1 (en) | 1999-08-31 | 2002-04-09 | Sts Biopolymers, Inc. | Anti-infective covering for percutaneous and vascular access device and coating method |
ES2258471T3 (es) | 1999-09-09 | 2006-09-01 | The Regents Of The University Of California | Suministro de liposomas cationicos de taxanos a vasos sanguineos angiogenicos. |
US6358557B1 (en) | 1999-09-10 | 2002-03-19 | Sts Biopolymers, Inc. | Graft polymerization of substrate surfaces |
US6358278B1 (en) | 1999-09-24 | 2002-03-19 | St. Jude Medical, Inc. | Heart valve prosthesis with rotatable cuff |
US6371983B1 (en) | 1999-10-04 | 2002-04-16 | Ernest Lane | Bioprosthetic heart valve |
WO2001025223A1 (en) | 1999-10-06 | 2001-04-12 | The Research Foundation Of State University Of New York | Stabilization of taxane-containing dispersed systems |
JP2003513756A (ja) * | 1999-11-12 | 2003-04-15 | アンジオテック ファーマシューティカルズ,インコーポレイテッド | 放射性治療と細胞周期インヒビターとの組合せの組成物 |
US20030144570A1 (en) * | 1999-11-12 | 2003-07-31 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors |
EP1113008A1 (en) * | 1999-12-29 | 2001-07-04 | Pfizer Products Inc. | 4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives useful as antibacterial and antiprotozoal agents |
CA2395132A1 (en) | 2000-01-05 | 2001-07-12 | Imarx Therapeutics, Inc. | Pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
US6383144B1 (en) * | 2000-01-18 | 2002-05-07 | Edwards Lifesciences Corporation | Devices and methods for measuring temperature of a patient |
EP1250166B1 (en) * | 2000-01-25 | 2010-03-17 | Edwards Lifesciences Corporation | Delivery systems for treatment of restenosis and anastomotic intimal hyperplasia |
US7011682B2 (en) * | 2000-01-31 | 2006-03-14 | Edwards Lifesciences Ag | Methods and apparatus for remodeling an extravascular tissue structure |
AU2869901A (en) | 2000-02-04 | 2001-08-14 | Lipoxen Technologies Limited | Liposomes |
GB0003201D0 (en) | 2000-02-11 | 2000-04-05 | Pharmacia & Upjohn Spa | Method to potentiate the therapeutic efficacy of taxane and derivatives thereof |
US6403618B1 (en) * | 2000-02-15 | 2002-06-11 | Novactyl, Inc. | Agent and method for controlling angiogenesis |
US6206749B1 (en) * | 2000-02-24 | 2001-03-27 | Dale L. Bell | Yo-yo |
US6370434B1 (en) | 2000-02-28 | 2002-04-09 | Cardiac Pacemakers, Inc. | Cardiac lead and method for lead implantation |
US7405080B2 (en) * | 2000-03-23 | 2008-07-29 | Voellmy Richard W | Compositions and methods relating to prevention of chemotherapy-induced alopecia |
AU2001253479A1 (en) * | 2000-04-13 | 2001-10-30 | Sts Biopolymers, Inc. | Targeted therapeutic agent release devices and methods of making and using the same |
US20010049422A1 (en) | 2000-04-14 | 2001-12-06 | Phaneuf Matthew D. | Methods of applying antibiotic compounds to polyurethane biomaterials using textile dyeing technology |
US6423050B1 (en) * | 2000-06-16 | 2002-07-23 | Zbylut J. Twardowski | Method and apparatus for locking of central-vein catheters |
US20040047910A1 (en) * | 2000-07-07 | 2004-03-11 | Christian Beckett | Suppository and composition comprising at least one polyethylene glycol |
US6685672B1 (en) * | 2000-07-13 | 2004-02-03 | Edwards Lifesciences Corporation | Multi-balloon drug delivery catheter for angiogenesis |
EP1309354A2 (en) | 2000-07-27 | 2003-05-14 | Rutgers, The State University | Therapeutic polyesters and polyamides |
DE10038617A1 (de) * | 2000-08-08 | 2002-02-21 | Degussa | Momomerarme 1 : 1 Monoaddukte aus Hydroxy(meth)-acrylaten und Diisocyanaten und Verfahren zu ihrer Herstellung |
US7304122B2 (en) * | 2001-08-30 | 2007-12-04 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
US6476636B1 (en) * | 2000-09-02 | 2002-11-05 | Actel Corporation | Tileable field-programmable gate array architecture |
WO2003026718A1 (en) * | 2000-10-31 | 2003-04-03 | Cook Incorporated | Coated implantable medical device |
US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
WO2002069949A2 (en) | 2001-03-06 | 2002-09-12 | Prendergast Patrick T | Combination therapy for reduction of toxycity of chemotherapeutic agents |
US7771468B2 (en) * | 2001-03-16 | 2010-08-10 | Angiotech Biocoatings Corp. | Medicated stent having multi-layer polymer coating |
KR20040005936A (ko) | 2001-04-26 | 2004-01-16 | 컨트롤 딜리버리 시스템즈 인코포레이티드 | 공동약물을 함유하는 서방 약물 전달 시스템 |
US7175873B1 (en) * | 2001-06-27 | 2007-02-13 | Advanced Cardiovascular Systems, Inc. | Rate limiting barriers for implantable devices and methods for fabrication thereof |
WO2003002165A1 (en) * | 2001-06-28 | 2003-01-09 | Cook Biotech Incorporated | Graft prosthesis devices containing renal capsule collagen |
US6559881B1 (en) * | 2001-07-17 | 2003-05-06 | Nokia Corporation | Video telecommunications device, and camera for same |
IN2014DN10834A (ru) * | 2001-09-17 | 2015-09-04 | Psivida Inc | |
US20030229390A1 (en) | 2001-09-17 | 2003-12-11 | Control Delivery Systems, Inc. | On-stent delivery of pyrimidines and purine analogs |
US6753071B1 (en) * | 2001-09-27 | 2004-06-22 | Advanced Cardiovascular Systems, Inc. | Rate-reducing membrane for release of an agent |
US20030134810A1 (en) * | 2001-10-09 | 2003-07-17 | Chris Springate | Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents |
US20030216758A1 (en) * | 2001-12-28 | 2003-11-20 | Angiotech Pharmaceuticals, Inc. | Coated surgical patches |
US20030144362A1 (en) | 2002-01-28 | 2003-07-31 | Utterberg David S. | High viscosity antibacterials for cannulae |
US20050042240A1 (en) * | 2002-01-28 | 2005-02-24 | Utterberg David S. | High viscosity antibacterials |
US6942633B2 (en) | 2002-03-22 | 2005-09-13 | Twin Star Medical, Inc. | System for treating tissue swelling |
RU2341296C2 (ru) * | 2002-05-24 | 2008-12-20 | Энджиотек Интернэшнл Аг | Композиции и способы покрытия медицинских имплантатов |
US6997894B2 (en) * | 2002-07-02 | 2006-02-14 | Caresio Joseph F | Vascular access catheter having a curved tip and method |
US7622146B2 (en) * | 2002-07-18 | 2009-11-24 | Advanced Cardiovascular Systems, Inc. | Rate limiting barriers for implantable devices and methods for fabrication thereof |
US6971813B2 (en) | 2002-09-27 | 2005-12-06 | Labcoat, Ltd. | Contact coating of prostheses |
US6786922B2 (en) | 2002-10-08 | 2004-09-07 | Cook Incorporated | Stent with ring architecture and axially displaced connector segments |
US6926919B1 (en) * | 2003-02-26 | 2005-08-09 | Advanced Cardiovascular Systems, Inc. | Method for fabricating a coating for a medical device |
US7255891B1 (en) * | 2003-02-26 | 2007-08-14 | Advanced Cardiovascular Systems, Inc. | Method for coating implantable medical devices |
US7306580B2 (en) | 2003-04-16 | 2007-12-11 | Cook Incorporated | Medical device with therapeutic agents |
US7201745B2 (en) * | 2003-05-13 | 2007-04-10 | Boston Scientific Scimed, Inc. | Anti-infective central venous catheter with diffusion barrier layer |
WO2005004966A1 (en) | 2003-07-02 | 2005-01-20 | Cook Critical Care Incorporated | Central venous catheter |
EP1660013A4 (en) | 2003-08-26 | 2011-07-20 | Gel Del Technologies Inc | BIOMATERIAL AND PROTEIN BIOCOACERVATES, METHODS OF MAKING AND USING THEM |
US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
US7004176B2 (en) * | 2003-10-17 | 2006-02-28 | Edwards Lifesciences Ag | Heart valve leaflet locator |
US20070249986A1 (en) | 2004-03-15 | 2007-10-25 | Smego Douglas R | Arteriovenous access for hemodialysis employing a vascular balloon catheter and an improved hybrid endovascular technique |
US7550444B2 (en) | 2004-03-26 | 2009-06-23 | Surmodics, Inc. | Composition and method for preparing biocompatible surfaces |
WO2005097222A1 (en) | 2004-03-26 | 2005-10-20 | Surmodics, Inc. | Process and systems for biocompatible surfaces |
US7238363B2 (en) | 2004-04-02 | 2007-07-03 | Baylor College Of Medicine | Modification of medical prostheses |
CA2563069A1 (en) | 2004-04-06 | 2005-10-27 | Surmodics, Inc. | Coating compositions for bioactive agents |
US20060083772A1 (en) | 2004-04-06 | 2006-04-20 | Dewitt David M | Coating compositions for bioactive agents |
US8241655B2 (en) | 2004-05-12 | 2012-08-14 | Surmodics, Inc. | Coatings for medical articles including natural biodegradable polysaccharides |
US20050281857A1 (en) | 2004-05-25 | 2005-12-22 | Heyer Toni M | Methods and reagents for preparing biomolecule-containing coatings |
US20060024372A1 (en) | 2004-07-29 | 2006-02-02 | Utterberg David S | High viscosity antibacterials |
US7807750B2 (en) | 2004-08-06 | 2010-10-05 | Surmodics, Inc. | Thermally-reactive polymers |
US8198326B2 (en) | 2004-09-07 | 2012-06-12 | 3M Innovative Properties Company | Phenolic antiseptic compositions and methods of use |
US20060051384A1 (en) | 2004-09-07 | 2006-03-09 | 3M Innovative Properties Company | Antiseptic compositions and methods of use |
US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
US20060147491A1 (en) | 2005-01-05 | 2006-07-06 | Dewitt David M | Biodegradable coating compositions including multiple layers |
US20060198868A1 (en) | 2005-01-05 | 2006-09-07 | Dewitt David M | Biodegradable coating compositions comprising blends |
US8109981B2 (en) | 2005-01-25 | 2012-02-07 | Valam Corporation | Optical therapies and devices |
EP1858438B1 (en) | 2005-03-15 | 2019-03-06 | SurModics, Inc. | Compliant polymeric coatings for insertable medical articles |
US7611505B2 (en) | 2005-05-10 | 2009-11-03 | Baxa Corporation | Sterile docking apparatus and method |
EP1893703B1 (en) | 2005-06-02 | 2009-12-30 | SurModics, Inc. | Hydrophilic polymeric coatings for medical articles |
CN101309709A (zh) | 2005-09-21 | 2008-11-19 | 苏尔莫迪克斯公司 | 包含天然生物可降解的多糖的涂层和物品 |
US20070259913A1 (en) | 2006-05-04 | 2007-11-08 | David Deitchman | Prophylaxis of thromboembolic events in cancer patients |
US7947019B2 (en) | 2006-08-18 | 2011-05-24 | Angio Dynamics, Inc | Catheter retention assembly and method of use |
US20080063627A1 (en) | 2006-09-12 | 2008-03-13 | Surmodics, Inc. | Tissue graft materials containing biocompatible agent and methods of making and using same |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2478385C2 (ru) * | 2007-05-22 | 2013-04-10 | Новартис Аг | Соединения триазола для лечения образования биопленок |
RU2551938C1 (ru) * | 2014-07-14 | 2015-06-10 | Общество с ограниченной ответственностью "Инновационная компания "Современные технологии" | Многоцелевой сосудистый имплант |
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