EP0828718A1
(en)
|
1995-06-02 |
1998-03-18 |
G.D. SEARLE & CO. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5908858A
(en)
*
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
TR199802049T2
(xx)
*
|
1996-04-12 |
1999-01-18 |
G.D.Searle & Co. |
COX-2 Inhibit�rlerinin �nilac� olarak s�bstit�e edilmi� benzens�lfonamid t�revleri.
|
US6586458B1
(en)
|
1996-08-16 |
2003-07-01 |
Pozen Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US8022095B2
(en)
|
1996-08-16 |
2011-09-20 |
Pozen, Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
DK0971714T3
(da)
*
|
1997-04-03 |
2002-11-04 |
Searle & Co |
Metode til anvendelse af cyklooxygenase-2-inhibitorer til behandling og forebyggelse af demens
|
US20040072889A1
(en)
*
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
RS49982B
(sr)
|
1997-09-17 |
2008-09-29 |
Euro-Celtique S.A., |
Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
|
NZ333399A
(en)
*
|
1997-12-24 |
2000-05-26 |
Sankyo Co |
Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis
|
US6136804A
(en)
*
|
1998-03-13 |
2000-10-24 |
Merck & Co., Inc. |
Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
|
JP2002506024A
(ja)
*
|
1998-03-13 |
2002-02-26 |
メルク エンド カムパニー インコーポレーテッド |
急性冠動脈虚血症候群および関連状態に対する併用療法および組成物
|
AU4428899A
(en)
|
1998-06-08 |
1999-12-30 |
Advanced Medicine, Inc. |
Multibinding inhibitors of cyclooxygenase-2
|
AR024222A1
(es)
*
|
1998-10-16 |
2002-09-25 |
Palau Pharma Sa |
Imidazoles con actividad antiinflamatoria un procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
|
WO2000025779A1
(en)
*
|
1998-11-02 |
2000-05-11 |
Merck & Co., Inc. |
Method of treating migraines and pharmaceutical compositions
|
AU1398899A
(en)
*
|
1998-11-12 |
2000-06-05 |
Algos Pharmaceutical Corporation |
Cox-2 inhibitors in combination with centrally acting analgesics
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
US20030119895A1
(en)
*
|
1998-12-23 |
2003-06-26 |
Pharmacia Corporation |
Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US6649645B1
(en)
|
1998-12-23 |
2003-11-18 |
Pharmacia Corporation |
Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
|
WO2000048583A2
(en)
*
|
1999-02-19 |
2000-08-24 |
Pozen Inc. |
Formulation of 5-ht agonists with nsaids, especially cox-2 inhibitors, for treating migraine
|
US20010024664A1
(en)
*
|
1999-03-19 |
2001-09-27 |
Obukowicz Mark G. |
Selective COX-2 inhibition from edible plant extracts
|
AU8026200A
(en)
|
1999-10-19 |
2001-04-30 |
Board Of Regents, The University Of Texas System |
Treatment of heart disease with cox-2 inhibitors
|
JP2003523954A
(ja)
*
|
1999-12-08 |
2003-08-12 |
ファルマシア コーポレイション |
治療効果が迅速に開始されるシクロオキシゲナーゼ−2阻害剤組成物
|
PT1239857E
(pt)
*
|
1999-12-22 |
2006-07-31 |
Pharmacia Corp |
Composicoes de libertacao dupla de um inibidor de ciclo-oxigenase-2
|
EP1246621A4
(en)
|
1999-12-23 |
2004-11-24 |
Nitromed Inc |
NITROSED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS FOR THEIR USE
|
AU3846801A
(en)
|
2000-02-16 |
2001-08-27 |
Brigham & Womens Hospital |
Aspirin-triggered lipid mediators
|
WO2001064669A1
(en)
|
2000-03-03 |
2001-09-07 |
Pfizer Products Inc. |
Pyrazole ether derivatives as anti-inflammatory/analgesic agents
|
US20070072861A1
(en)
*
|
2000-03-27 |
2007-03-29 |
Barbara Roniker |
Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders
|
WO2001081333A2
(en)
*
|
2000-04-25 |
2001-11-01 |
Pharmacia Corporation |
Regioselective synthesis of 3,4-di(carbocyclyl or heterocyclyl)thiophenes
|
ES2166710B1
(es)
*
|
2000-04-25 |
2004-10-16 |
J. URIACH & CIA, S.A. |
Nuevos compuestos heterociclicos con actividad antiinflamatoria.
|
CA2414674A1
(en)
*
|
2000-07-13 |
2002-01-24 |
Pharmacia Corporation |
Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
|
PT1303265E
(pt)
|
2000-07-20 |
2007-10-09 |
Lauras As |
''utilização de inibidores da cox-2 como imuno-estimulantes, no tratamento do vih ou da sida''
|
US20030219461A1
(en)
*
|
2000-09-12 |
2003-11-27 |
Britten Nancy J. |
Parenteral combination therapy for infective conditions
|
AU2001295038A1
(en)
*
|
2000-09-18 |
2002-03-26 |
Merck & Co., Inc. |
Treatment of inflammation with a combination of a cyclooxygenase-2 inhibitor and an integrin alpha-V antagonist
|
EP1578341A4
(en)
*
|
2000-10-11 |
2005-09-28 |
Tularik Inc |
MODULATION OF THE CCR4 FUNCTION
|
US20020122836A1
(en)
*
|
2000-12-15 |
2002-09-05 |
Pharmacia Corporation |
Selective COX-2 inhibition from non-edible plant extracts
|
AU2002229074A1
(en)
*
|
2000-12-15 |
2002-06-24 |
Pharmacia Corporation |
Selective cox-2 inhibition from plant extracts
|
CA2432642A1
(en)
|
2000-12-21 |
2002-08-08 |
Subhash P. Khanapure |
Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
US7115565B2
(en)
*
|
2001-01-18 |
2006-10-03 |
Pharmacia & Upjohn Company |
Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
|
US20050143360A1
(en)
*
|
2001-02-02 |
2005-06-30 |
Joel Krasnow |
Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
|
AU2002306868A1
(en)
*
|
2001-03-28 |
2002-10-15 |
Pharmacia Corporation |
Therapeutic combinations for cardiovascular and inflammatory indications
|
US7695736B2
(en)
*
|
2001-04-03 |
2010-04-13 |
Pfizer Inc. |
Reconstitutable parenteral composition
|
ITMI20010733A1
(it)
|
2001-04-05 |
2002-10-05 |
Recordati Chem Pharm |
Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria
|
US20030105144A1
(en)
*
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
WO2002094264A1
(en)
*
|
2001-05-23 |
2002-11-28 |
Tularik Inc. |
Ccr4 antagonists
|
US20030153801A1
(en)
*
|
2001-05-29 |
2003-08-14 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and radiation for inhibition or prevention of cardiovascular disease
|
HUP0600294A2
(en)
*
|
2001-05-31 |
2007-02-28 |
Pharmacia Corp |
Skin-permeable selective cyclooxygenase-2 inhibitor composition
|
US20060167074A1
(en)
*
|
2001-06-19 |
2006-07-27 |
Norbert Muller |
Methods and compositions for the treatment of psychiatric disorders
|
DE10129320A1
(de)
*
|
2001-06-19 |
2003-04-10 |
Norbert Mueller |
Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
|
UA80682C2
(en)
*
|
2001-08-06 |
2007-10-25 |
Pharmacia Corp |
Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
|
US20040067992A1
(en)
*
|
2001-08-10 |
2004-04-08 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia
|
CA2456939A1
(en)
*
|
2001-08-10 |
2003-02-20 |
Pharmacia Corporation |
Carbonic anhydrase inhibitors
|
US20030114416A1
(en)
*
|
2001-08-14 |
2003-06-19 |
Pharmacia Corporation |
Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
|
US20050101563A1
(en)
*
|
2001-08-14 |
2005-05-12 |
Pharmacia Corporation |
Method and compositions for the treatment and prevention of pain and inflammation
|
AR038957A1
(es)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
WO2003022815A1
(en)
*
|
2001-09-10 |
2003-03-20 |
Sugen, Inc. |
3-(4,5,6,7-tetrahydroindol-2-ylmethylidiene)-2-indolinone derivatives as kinase inhibitors
|
US20030236308A1
(en)
*
|
2001-09-18 |
2003-12-25 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
US6906196B2
(en)
*
|
2001-09-18 |
2005-06-14 |
Onconova Therapeutics, Inc. |
Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles
|
WO2003024400A2
(en)
|
2001-09-18 |
2003-03-27 |
Onconova Therapeutics, Inc. |
Process for the preparation of 1,5-diarylpyrazoles
|
US20030114483A1
(en)
*
|
2001-09-18 |
2003-06-19 |
Pharmacia Corporation |
Compositions of chromene cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
WO2003024936A1
(en)
*
|
2001-09-19 |
2003-03-27 |
Pharmacia Corporation |
Substituted pyrazolo compounds for the treatment of inflammation
|
AU2002337804B2
(en)
*
|
2001-10-02 |
2008-06-26 |
Pharmacia Corporation |
Method for preparing benzenesulfonyl compounds
|
AR037097A1
(es)
|
2001-10-05 |
2004-10-20 |
Novartis Ag |
Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
|
AU2002337843A1
(en)
*
|
2001-10-12 |
2003-04-22 |
Onconova Therapeutics, Inc. |
Processes for the preparation of substituted isoxazoles and 2-isoxazolines
|
US20030162824A1
(en)
*
|
2001-11-12 |
2003-08-28 |
Krul Elaine S. |
Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor
|
CN1615135A
(zh)
*
|
2001-11-13 |
2005-05-11 |
法马西亚公司 |
磺酰胺前药如帕瑞考昔的口服剂型
|
ATE424388T1
(de)
|
2001-12-06 |
2009-03-15 |
Merck & Co Inc |
Mitotische kinesinhemmer
|
EP1463505A2
(en)
*
|
2001-12-13 |
2004-10-06 |
Abbott Laboratories |
3-(phenyl-alkoxy)-5-(phenyl)-pyridine derivatives and related compounds as kinase inhibitors for the treatment of cancer
|
US20040126438A1
(en)
*
|
2001-12-13 |
2004-07-01 |
Obukowicz Mark G. |
Selective cox-2 inhibition from plant extracts
|
US20040062823A1
(en)
*
|
2001-12-13 |
2004-04-01 |
Obukowicz Mark G. |
Selective cox-2 inhibition from non-edible plant extracts
|
MXPA04006572A
(es)
*
|
2002-01-10 |
2005-11-04 |
Upjohn Co |
Terapia de combinacion antivirica.
|
US20030220374A1
(en)
*
|
2002-01-14 |
2003-11-27 |
Pharmacia Corporation |
Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
|
US20030212138A1
(en)
*
|
2002-01-14 |
2003-11-13 |
Pharmacia Corporation |
Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
|
TW200403072A
(en)
*
|
2002-01-23 |
2004-03-01 |
Upjohn Co |
Combination therapy for the treatment of bacterial infections
|
US7927613B2
(en)
*
|
2002-02-15 |
2011-04-19 |
University Of South Florida |
Pharmaceutical co-crystal compositions
|
US20100311701A1
(en)
*
|
2002-02-15 |
2010-12-09 |
Transform Pharmaceuticals, Inc |
Pharmaceutical Co-Crystal Compositions
|
US20030224006A1
(en)
*
|
2002-03-01 |
2003-12-04 |
Zaworotko Michael J. |
Multiple-component solid phases containing at least one active pharmaceutical ingredient
|
WO2004026235A2
(en)
*
|
2002-09-20 |
2004-04-01 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical compositions with improved dissolution
|
US7790905B2
(en)
*
|
2002-02-15 |
2010-09-07 |
Mcneil-Ppc, Inc. |
Pharmaceutical propylene glycol solvate compositions
|
EP1915992A1
(en)
|
2002-02-19 |
2008-04-30 |
Pharmacia Corporation |
Use of cyclooxygenase inhibitors and antimuscarinic agents for the treatment of incontinence
|
PL372880A1
(en)
*
|
2002-03-15 |
2005-08-08 |
Pharmacia Corporation |
Crystalline parecoxib sodium
|
US8481772B2
(en)
|
2002-04-01 |
2013-07-09 |
University Of Southern California |
Trihydroxy polyunsaturated eicosanoid derivatives
|
US7902257B2
(en)
|
2002-04-01 |
2011-03-08 |
University Of Southern California |
Trihydroxy polyunsaturated eicosanoid
|
CN1659131A
(zh)
|
2002-04-08 |
2005-08-24 |
葛兰素集团有限公司 |
2-((2-烷氧基)-苯基)-环戊-1-烯基)芳香碳-以及杂环羧酸及其衍生物
|
US20040034083A1
(en)
*
|
2002-04-18 |
2004-02-19 |
Stephenson Diane T. |
Combination therapy for the treatment of Parkinson's disease with cyclooxygenase-2 (COX2) inhibitor(s)
|
JP2005532293A
(ja)
*
|
2002-04-18 |
2005-10-27 |
ファルマシア・コーポレーション |
シクロオキシゲナーゼ−2(cox2)阻害剤を用いたパーキンソン病の治療のための単剤療法
|
AU2003229016A1
(en)
*
|
2002-05-10 |
2003-11-11 |
The Trustees Of Columbia University In The City Of New York |
Genetically engineered cell lines and systems for propagatingvaricella zoster virus and methods of use thereof
|
IL165383A0
(en)
*
|
2002-06-21 |
2006-01-15 |
Transform Pharmaceuticals Inc |
Pharmaceutical compositions with improved dissolution
|
WO2004002533A1
(en)
*
|
2002-06-26 |
2004-01-08 |
Pharmacia Corporation |
Stable liquid parenteral parecoxib formulation
|
US7087630B2
(en)
|
2002-06-27 |
2006-08-08 |
Nitromed, Inc. |
Cyclooxygenase 2 selective inhibitors, compositions and methods of use
|
WO2004002420A2
(en)
|
2002-06-28 |
2004-01-08 |
Nitromed, Inc. |
Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use
|
CA2491479A1
(en)
*
|
2002-07-02 |
2004-01-15 |
Pharmacia Corporation |
Use of cyclooxygenase-2 selective inhibitors and thrombolytic agents for the treatment or prevention of a vaso-occlusive event
|
ES2700133T3
(es)
*
|
2002-08-12 |
2019-02-14 |
Brigham & Womens Hospital |
Resolvinas: modelos biológicos para intervenciones terapéuticas
|
US7759395B2
(en)
*
|
2002-08-12 |
2010-07-20 |
The Brigham And Women's Hospital, Inc. |
Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
|
UY27939A1
(es)
|
2002-08-21 |
2004-03-31 |
Glaxo Group Ltd |
Compuestos
|
KR100484525B1
(ko)
*
|
2002-10-15 |
2005-04-20 |
씨제이 주식회사 |
이소티아졸 유도체, 그 제조방법 및 약제학적 조성물
|
US20040082543A1
(en)
*
|
2002-10-29 |
2004-04-29 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
|
GB0225548D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
US20040092566A1
(en)
*
|
2002-11-12 |
2004-05-13 |
Graneto Matthew J. |
Celecoxib prodrug
|
US20040147581A1
(en)
*
|
2002-11-18 |
2004-07-29 |
Pharmacia Corporation |
Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
|
US20050020658A1
(en)
*
|
2002-11-21 |
2005-01-27 |
Katsuyuki Inoo |
Selective cyclooxygenase-2 inhibitor patch
|
US20040126415A1
(en)
*
|
2002-11-21 |
2004-07-01 |
Lu Guang Wei |
Dermal delivery of a water-soluble selective cyclooxygenase-2 inhibitor
|
US20040127531A1
(en)
*
|
2002-11-21 |
2004-07-01 |
Lu Guang Wei |
Adhesive coated sheet for dermal delivery of a selective cyclooxygenase-2 inhibitor
|
CA2509605C
(en)
|
2002-12-13 |
2010-10-05 |
Warner-Lambert Company Llc |
Alpha-2-delta ligand to treat lower urinary tract symptoms
|
US20040204411A1
(en)
*
|
2002-12-17 |
2004-10-14 |
Pharmacia Corporation |
Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
|
US20040235925A1
(en)
*
|
2002-12-17 |
2004-11-25 |
Pharmacia Corporation |
Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
|
US20080153894A1
(en)
*
|
2002-12-19 |
2008-06-26 |
Pharmacia Corporation |
Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis
|
KR20050085724A
(ko)
*
|
2002-12-19 |
2005-08-29 |
파마시아 코포레이션 |
시클로옥시게나제-2 선택적인 억제제 또는시클로옥시게나제-2 억제제와 항바이러스제의 조합 제제를사용하는 헤르페스 바이러스 감염 치료를 위한 방법 및조성물
|
US20040171664A1
(en)
*
|
2002-12-20 |
2004-09-02 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and selective serotonin reuptake inhibitors for the treatment or prevention of a vaso-occlusive event
|
ES2215474B1
(es)
|
2002-12-24 |
2005-12-16 |
J. URIACH & CIA S.A. |
Nuevos derivados de fosforamida.
|
WO2004060355A1
(en)
|
2002-12-26 |
2004-07-22 |
Pozen Inc. |
Multilayer Dosage Forms Containing NSAIDs and Triptans
|
WO2004060367A1
(en)
*
|
2002-12-30 |
2004-07-22 |
Fujisawa Pharmaceutical Co., Ltd. |
Imidazole and triazole derivatives useful as selective cox-1 inhibitors
|
US8183290B2
(en)
|
2002-12-30 |
2012-05-22 |
Mcneil-Ppc, Inc. |
Pharmaceutically acceptable propylene glycol solvate of naproxen
|
US20050026902A1
(en)
*
|
2003-01-31 |
2005-02-03 |
Timothy Maziasz |
Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents
|
US20040176378A1
(en)
*
|
2003-02-12 |
2004-09-09 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an amphetamine for the treatment of reduced blood flow to the central nervous system
|
WO2004078143A2
(en)
*
|
2003-03-05 |
2004-09-16 |
The Brigham And Women's Hospital Inc. |
Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs
|
BRPI0408556A
(pt)
*
|
2003-03-20 |
2006-03-21 |
Pharmacia Corp |
formulações dispersìvel de um agente antiinflamatório
|
US20050004098A1
(en)
*
|
2003-03-20 |
2005-01-06 |
Britten Nancy Jean |
Dispersible formulation of an anti-inflammatory agent
|
US20050009931A1
(en)
*
|
2003-03-20 |
2005-01-13 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040214753A1
(en)
*
|
2003-03-20 |
2004-10-28 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040220155A1
(en)
*
|
2003-03-28 |
2004-11-04 |
Pharmacia Corporation |
Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
|
US20040214861A1
(en)
*
|
2003-03-28 |
2004-10-28 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine
|
AU2003238669A1
(en)
*
|
2003-04-04 |
2004-10-25 |
Hetero Drugs Limited |
Novel crystalline forms of parecoxib sodium
|
MXPA05010937A
(es)
*
|
2003-04-14 |
2005-11-25 |
Inst For Pharm Discovery Inc |
Derivados de fenilalanina n-(1,3-tiazol-2-il)amino)carbonil)fenil)sulfonil) y compuestos relacionados para el tratamiento de diabetes.
|
US20060135506A1
(en)
*
|
2003-04-22 |
2006-06-22 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders
|
US20040229803A1
(en)
*
|
2003-04-22 |
2004-11-18 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of pain, inflammation or inflammation mediated disorders
|
US20050009733A1
(en)
*
|
2003-04-22 |
2005-01-13 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of central nervous system damage
|
US20040224940A1
(en)
*
|
2003-04-22 |
2004-11-11 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium ion channel blocker for the treatment of central nervous system damage
|
US20040220187A1
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium ion channel blocker for the treatment of pain, inflammation or inflammation mediated disorders
|
US20050159403A1
(en)
*
|
2003-04-22 |
2005-07-21 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of central nervous system damage
|
CA2523714A1
(en)
|
2003-04-30 |
2004-11-18 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted carboxylic acids
|
US20040220167A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Nasrollah Samiy |
Methods of treating neuralgic pain
|
AU2004237439B2
(en)
|
2003-05-07 |
2009-09-10 |
Osteologix A/S |
Treating cartilage/bone conditions with water-soluble strontium salts
|
US20050107387A1
(en)
*
|
2003-05-13 |
2005-05-19 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
|
WO2004103283A2
(en)
*
|
2003-05-14 |
2004-12-02 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a central nervous system stimulant for the treatment of central nervous system damage
|
WO2004103286A2
(en)
*
|
2003-05-14 |
2004-12-02 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cholimergic agent
|
CA2525571A1
(en)
*
|
2003-05-14 |
2004-12-02 |
Pharmacia Corporation |
Compositions of a benzenesulfonamide or methylsulfonylbenzene cyclooxygenase-2 selective inhibitor and a cholinergic agent for the treatment of reduced blood flow or trauma to thecentral nervous system
|
CA2525280A1
(en)
*
|
2003-05-14 |
2004-12-02 |
Pharmacia Corporation |
Compositions for the treatment of reduced blood flow
|
US20050113376A1
(en)
*
|
2003-05-27 |
2005-05-26 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor, a xanthine compound and an alcohol for the treatment of ischemic mediated central nervous system disorders or injury
|
US20060160776A1
(en)
*
|
2003-05-28 |
2006-07-20 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage
|
WO2004106299A2
(en)
|
2003-05-30 |
2004-12-09 |
Ranbaxy Laboratories Limited |
Substituted pyrrole derivatives and their use as hmg-co inhibitors
|
US20050054646A1
(en)
*
|
2003-06-09 |
2005-03-10 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an antioxidant agent for the treatment of central nervous system disorders
|
US20050065154A1
(en)
*
|
2003-06-24 |
2005-03-24 |
Pharmacia Corporation |
Treatment of migraine accompanied by nausea with a combination of cyclooxygenase-2 selective inhibitors and anti-nausea agents
|
WO2005007106A2
(en)
*
|
2003-07-10 |
2005-01-27 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a non-nmda glutamate modulator for the treatment of central nervous system damage
|
WO2005007156A1
(en)
*
|
2003-07-10 |
2005-01-27 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an angiotensin ii receptor antagonist for the treatment of central nervous system damage
|
WO2005018541A2
(en)
*
|
2003-07-11 |
2005-03-03 |
Pharmacia Corporation |
Cox-2 inhibitor and serotonin modulator for treating cns damage
|
US20050070543A1
(en)
*
|
2003-07-11 |
2005-03-31 |
Pharmacia Corporation |
Compositions of a chromene or phenyl acetic acid cyclooxygenase-2 selective inhibitor and an ACE inhibitor for the treatment of central nervous system damage
|
US20050014729A1
(en)
*
|
2003-07-16 |
2005-01-20 |
Pharmacia Corporation |
Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
|
WO2005009354A2
(en)
*
|
2003-07-17 |
2005-02-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an ikk inhibitor for the treatment of ischemic-mediated central nervous system disorders or injury
|
US7825146B2
(en)
*
|
2003-07-30 |
2010-11-02 |
Shionogi & Co., Ltd. |
Sulfonamide derivative having isoxazole ring
|
CA2536173A1
(en)
*
|
2003-08-20 |
2005-03-03 |
Nitromed, Inc. |
Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
|
US20050119262A1
(en)
*
|
2003-08-21 |
2005-06-02 |
Pharmacia Corporation |
Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
|
JP2007503396A
(ja)
*
|
2003-08-22 |
2007-02-22 |
ファルマシア コーポレイション |
新形成の治療のためのシクロオキシゲナーゼ−2選択的阻害剤及びセロトニン−調節剤の組成物
|
US20050130971A1
(en)
*
|
2003-08-22 |
2005-06-16 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and phosphodiesterase inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
|
WO2005018564A2
(en)
*
|
2003-08-22 |
2005-03-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a low-molecular-weight heparin for the treatment of central nervous system damage
|
US20050107350A1
(en)
*
|
2003-08-22 |
2005-05-19 |
Pharmacia Corporation |
Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
|
US20050085479A1
(en)
*
|
2003-08-27 |
2005-04-21 |
Pharmacia Corporation |
Mediated central nervous system compositions of a cyclooxygenase-2 selective inhibitor and a corticotropin releasing factor antagonist for the treatment of ischemic disorders or injury
|
US20050187278A1
(en)
*
|
2003-08-28 |
2005-08-25 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
|
US7282519B2
(en)
*
|
2003-08-28 |
2007-10-16 |
Nitromed, Inc. |
Nitrosated and nitrosylated diuretic compounds, compositions and methods of use
|
WO2005023189A2
(en)
*
|
2003-09-03 |
2005-03-17 |
Pharmacia Corporation |
Method of cox-2 selective inhibitor and nitric oxide-donating agent
|
EP1670417A2
(en)
*
|
2003-10-03 |
2006-06-21 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor administered under hypothermic conditions for the treatment of ischenic mediated central nervous system disorders or injury
|
JP2007510756A
(ja)
*
|
2003-11-12 |
2007-04-26 |
ファルマシア・アンド・アップジョン・カンパニー・エルエルシー |
中枢神経系介在障害を治療するためのシクロオキシゲナーゼ−2選択的阻害剤及び神経栄養因子調節剤の組成物
|
EP1708700A1
(en)
*
|
2003-12-24 |
2006-10-11 |
Pharmacia Corporation |
Metal salts of parecoxib as prodrugs of the cox-2 inhibitor valdecoxib for the treatment of inflammation, pain and/or fever
|
US7449462B2
(en)
|
2004-01-22 |
2008-11-11 |
Pfizer, Inc. |
Triazole derivatives which inhibit vasopressin antagonistic activity
|
WO2005105025A1
(en)
*
|
2004-04-14 |
2005-11-10 |
Boston University |
Methods and compositions for preventing or treating periodontal diseases
|
MXPA06012510A
(es)
*
|
2004-04-28 |
2006-12-15 |
Pfizer |
Derivados de 3-heterociclil-4-fenil-triazol como inhibidores del receptor de vasopresina via.
|
MXPA06015275A
(es)
|
2004-07-01 |
2007-03-15 |
Merck & Co Inc |
Inhibidores de quinasa mitotica.
|
ES2257929B1
(es)
*
|
2004-07-16 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
|
AU2005266088A1
(en)
*
|
2004-07-22 |
2006-02-02 |
Pharmacia Corporation |
Compositions for treatment of inflammation and pain using a combination of a COX-2 selective inhibitor and a LTB4 receptor antagonist
|
US8067464B2
(en)
|
2004-10-04 |
2011-11-29 |
Nitromed, Inc. |
Compositions and methods using apocynin compounds and nitric oxide donors
|
AU2005304770A1
(en)
*
|
2004-11-08 |
2006-05-18 |
Nicox S.A. |
Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
|
DE602005013116D1
(de)
|
2004-12-23 |
2009-04-16 |
Glaxo Group Ltd |
Pyridin-verbindungen für die behandlung von prostaglandin-vermittelten krankheiten
|
AU2006206249A1
(en)
*
|
2005-01-21 |
2006-07-27 |
Nicox S.A. |
Cardiovascular compounds comprising heterocyclic nitric oxide donor group compositions and methods of use
|
CA2597422A1
(en)
*
|
2005-02-16 |
2007-08-02 |
Nitromed, Inc. |
Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
|
US7521435B2
(en)
|
2005-02-18 |
2009-04-21 |
Pharma Diagnostics, N.V. |
Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
|
WO2006093864A1
(en)
*
|
2005-02-28 |
2006-09-08 |
Nitromed, Inc. |
Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
|
MX2007013304A
(es)
|
2005-04-26 |
2007-12-13 |
Pfizer |
Anticuerpos de p-caderina.
|
AU2006244393B2
(en)
*
|
2005-05-05 |
2012-06-21 |
Cook Biotech Incorporated |
Implantable materials and methods for inhibiting tissue adhesion formation
|
EP1888050B1
(en)
|
2005-05-17 |
2012-03-21 |
Merck Sharp & Dohme Ltd. |
cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid for the treatment of cancer
|
US20080234252A1
(en)
*
|
2005-05-18 |
2008-09-25 |
Pfizer Inc |
Compounds Useful in Therapy
|
WO2006127591A2
(en)
*
|
2005-05-23 |
2006-11-30 |
Nitromed, Inc. |
Organic nitric oxide enhancing salts of nonsteroidal antiinflammatory compounds, compositions and methods of use
|
HUP0500730A2
(en)
*
|
2005-07-29 |
2007-02-28 |
Richter Gedeon Vegyuszeti Gyar |
1,2-diaryl-heterocyclic compounds, their preparation, pharmaceutical compositions comprising thereof and their use
|
WO2007016677A2
(en)
|
2005-08-02 |
2007-02-08 |
Nitromed, Inc. |
Nitric oxide enhancing antimicrobial compounds, compositions and methods of use
|
PE20070335A1
(es)
*
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Benzimidazoles sustituidos y metodos para su preparacion
|
PT2447283E
(pt)
|
2005-09-07 |
2015-10-08 |
Pfizer |
Anticorpos monoclonais humanos para cinase-1 tipo recetor de activina (alk-1)
|
WO2007041440A2
(en)
*
|
2005-10-03 |
2007-04-12 |
The Brigham And Women's Hospital, Inc. |
Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers
|
EP1942909A4
(en)
*
|
2005-10-04 |
2010-01-06 |
Nitromed Inc |
METHODS OF TREATING RESPIRATORY DISORDERS
|
KR101329112B1
(ko)
|
2005-11-08 |
2013-11-14 |
랜박시 래보러터리스 리미티드 |
(3r,5r)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
|
US7838023B2
(en)
*
|
2005-11-16 |
2010-11-23 |
Nitromed, Inc. |
Furoxan compounds, compositions and methods of use
|
US8636986B2
(en)
*
|
2005-11-18 |
2014-01-28 |
The Forsyth Institute |
Treatment and prevention of bone loss using resolvins
|
EP1968584A2
(en)
*
|
2005-12-20 |
2008-09-17 |
Nitromed, Inc. |
Nitric oxide enhancing glutamic acid compounds, compositions and methods of use
|
NL2000351C2
(nl)
|
2005-12-22 |
2007-09-11 |
Pfizer Prod Inc |
Estrogeen-modulatoren.
|
EP1971340A2
(en)
*
|
2005-12-22 |
2008-09-24 |
Nitromed, Inc. |
Nitric oxide enhancing pyruvate compounds, compositions and methods of use
|
US20090062302A1
(en)
|
2006-01-24 |
2009-03-05 |
Buser-Doepner Carolyn A |
Jak2 Tyrosine Kinase Inhibition
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
CA2647859C
(en)
|
2006-03-29 |
2016-01-05 |
Nitromed, Inc. |
Nitric oxide enhancing prostaglandin compounds, compositions and methods of use
|
MX2008013427A
(es)
|
2006-04-19 |
2008-11-04 |
Novartis Ag |
Compuestos de benzoxazole y benzotiazole sustituidos-6-0 y metodos para inhibir la señalizacion csf-1r.
|
CA2651732C
(en)
|
2006-05-18 |
2014-10-14 |
Mannkind Corporation |
Intracellular kinase inhibitors
|
WO2008033931A1
(en)
*
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
|
WO2008039327A2
(en)
|
2006-09-22 |
2008-04-03 |
Merck & Co., Inc. |
Method of treatment using fatty acid synthesis inhibitors
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
KR20090092307A
(ko)
|
2006-12-22 |
2009-08-31 |
레코르다티 아일랜드 리미티드 |
하요도 장애에 대한 α2δ 리간드 및 NSAIDs의 복합 치료
|
MX2009007200A
(es)
|
2007-01-10 |
2009-07-15 |
Angeletti P Ist Richerche Bio |
Indazoles sustituidos con amida como inhibidores de poli(adp-ribosa)polimerasa (parp).
|
KR100843351B1
(ko)
*
|
2007-01-30 |
2008-07-03 |
한국과학기술연구원 |
중추신경계 질환 치료제로 유효한n-벤질-n-(2-디메틸아미노-에틸)-벤젠술폰아미드 화합물
|
EP2132177B1
(en)
|
2007-03-01 |
2013-07-17 |
Novartis AG |
Pim kinase inhibitors and methods of their use
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
EP2152700B1
(en)
|
2007-05-21 |
2013-12-11 |
Novartis AG |
Csf-1r inhibitors, compositions, and methods of use
|
AU2008269154B2
(en)
|
2007-06-27 |
2014-06-12 |
Merck Sharp & Dohme Llc |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
AU2008274941A1
(en)
|
2007-07-12 |
2009-01-15 |
Tragara Pharmaceuticals, Inc. |
Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
CN101854933A
(zh)
|
2007-09-10 |
2010-10-06 |
钙医学公司 |
调节细胞内钙的化合物
|
JP2011515343A
(ja)
|
2008-03-03 |
2011-05-19 |
タイガー ファーマテック |
チロシンキナーゼ阻害薬
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
KR101724161B1
(ko)
|
2008-08-27 |
2017-04-06 |
칼시메디카, 인크 |
세포내 칼슘을 조절하는 화합물
|
EP2177215A1
(en)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-crystals of tramadol and NSAIDs
|
GB0903493D0
(en)
|
2009-02-27 |
2009-04-08 |
Vantia Ltd |
New compounds
|
JP5212177B2
(ja)
*
|
2009-02-27 |
2013-06-19 |
東レ株式会社 |
γ−ケトアセタール化合物及びピロール誘導体の製造方法
|
KR101069175B1
(ko)
|
2009-04-19 |
2011-09-30 |
중앙대학교 산학협력단 |
신규 아미노설포닐아릴이소옥사졸계 화합물 및 이를 포함하는 다약제내성 억제용 약제학적 조성물
|
WO2011012622A1
(en)
|
2009-07-30 |
2011-02-03 |
Glaxo Group Limited |
Benzoxazinone derivatives for the treatment of glytl mediated disorders
|
WO2011023753A1
(en)
|
2009-08-27 |
2011-03-03 |
Glaxo Group Limited |
Benzoxazine derivatives as glycine transport inhibitors
|
EA023838B1
(ru)
|
2009-10-14 |
2016-07-29 |
Мерк Шарп Энд Домэ Корп. |
ЗАМЕЩЕННЫЕ ПИПЕРИДИНЫ, КОТОРЫЕ ПОВЫШАЮТ АКТИВНОСТЬ p53, И ИХ ПРИМЕНЕНИЕ
|
GB201000685D0
(en)
|
2010-01-15 |
2010-03-03 |
Glaxo Group Ltd |
Novel compounds
|
CN101805290A
(zh)
*
|
2010-04-01 |
2010-08-18 |
中国人民解放军第四军医大学 |
氨基磺酰吡唑类化合物及其用途
|
AU2011248877B9
(en)
|
2010-04-27 |
2015-11-05 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
AU2011248579A1
(en)
|
2010-04-27 |
2012-11-29 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
GB201007791D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel compounds
|
GB201007789D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel Compound
|
WO2011145022A1
(en)
|
2010-05-21 |
2011-11-24 |
Pfizer Inc. |
2-phenyl benzoylamides
|
EP2584903B1
(en)
|
2010-06-24 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
JP5815029B2
(ja)
|
2010-07-09 |
2015-11-17 |
クオンベルゲンセ プハルマセウトイカルス リミテッド |
カルシウムチャネル遮断薬としてのテトラゾール化合物
|
WO2012018754A2
(en)
|
2010-08-02 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
CA2807307C
(en)
|
2010-08-17 |
2021-02-09 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of hepatitis b virus (hbv) gene expression using short interfering nucleic acid (sina)
|
US8653118B2
(en)
*
|
2010-08-20 |
2014-02-18 |
Allergan, Inc. |
Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
|
EP2608669B1
(en)
|
2010-08-23 |
2016-06-22 |
Merck Sharp & Dohme Corp. |
NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
MX337711B
(es)
|
2010-08-27 |
2016-03-15 |
Calcimedica Inc |
Compuestos que modulan el calcio intracelular.
|
US8946216B2
(en)
|
2010-09-01 |
2015-02-03 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
EP2615916B1
(en)
|
2010-09-16 |
2017-01-04 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel erk inhibitors
|
US9260471B2
(en)
|
2010-10-29 |
2016-02-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
|
EP2654748B1
(en)
|
2010-12-21 |
2016-07-27 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as erk inhibitors
|
US8933132B2
(en)
|
2011-01-19 |
2015-01-13 |
Convergence Pharmaceuticals Limited |
Tricyclic substituted benzenesulfonamide piperazine derivatives as CAV2.2 calcium channel blockers
|
EP2680874A2
(en)
|
2011-03-04 |
2014-01-08 |
Pfizer Inc |
Edn3-like peptides and uses thereof
|
AU2012245971A1
(en)
|
2011-04-21 |
2013-10-17 |
Piramal Enterprises Limited |
A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
US9221809B2
(en)
|
2011-10-31 |
2015-12-29 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
|
US9562015B2
(en)
|
2011-11-17 |
2017-02-07 |
The Regents Of The University Of Colorado, A Body |
Methods and compositions for enhanced drug delivery to the eye and extended delivery formulations
|
GB201122113D0
(en)
|
2011-12-22 |
2012-02-01 |
Convergence Pharmaceuticals |
Novel compounds
|
EP3453762B1
(en)
|
2012-05-02 |
2021-04-21 |
Sirna Therapeutics, Inc. |
Short interfering nucleic acid (sina) compositions
|
JP6280554B2
(ja)
|
2012-09-28 |
2018-02-14 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
Erk阻害剤である新規化合物
|
US9512116B2
(en)
|
2012-10-12 |
2016-12-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
ME02925B
(me)
|
2012-11-28 |
2018-04-20 |
Merck Sharp & Dohme |
Kompozicije i postupci za liječenje kancera
|
TW201429969A
(zh)
|
2012-12-20 |
2014-08-01 |
Merck Sharp & Dohme |
作爲hdm2抑制劑之經取代咪唑吡啶
|
EP2951180B1
(en)
|
2013-01-30 |
2018-05-02 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
CA2911376C
(en)
*
|
2013-03-15 |
2021-03-30 |
University Of Southern California |
Phenyl(sulfonylcarbamate) derivatives and pharmaceutical compositions thereof for the treatment of angiotensin-related diseases
|
US20160166576A1
(en)
|
2013-07-11 |
2016-06-16 |
Merck Sharp & Dohme Corp. |
Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
CN104418818B
(zh)
*
|
2013-09-04 |
2017-01-11 |
天津汉瑞药业有限公司 |
帕瑞昔布钠无水化合物
|
US9611263B2
(en)
|
2013-10-08 |
2017-04-04 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
CN105085425B
(zh)
*
|
2014-05-23 |
2018-01-30 |
昆药集团股份有限公司 |
一种制备帕瑞昔布的方法
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
GB201417499D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417500D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417497D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
CN104557754A
(zh)
*
|
2015-01-04 |
2015-04-29 |
成都克莱蒙医药科技有限公司 |
一种帕瑞昔布钠杂质的合成方法
|
US10329294B2
(en)
|
2015-03-12 |
2019-06-25 |
Merck Sharp & Dohme Corp. |
Pyrazolopyrimidine inhibitors of IRAK4 activity
|
EP3268367B8
(en)
|
2015-03-12 |
2022-11-16 |
Merck Sharp & Dohme LLC |
Carboxamide inhibitors of irak4 activity
|
WO2016144849A1
(en)
|
2015-03-12 |
2016-09-15 |
Merck Sharp & Dohme Corp. |
Thienopyrazine inhibitors of irak4 activity
|
MX2018001300A
(es)
*
|
2015-07-31 |
2019-03-14 |
Univ Johns Hopkins |
Profarmacos de analogos de glutamina.
|
US9598361B1
(en)
*
|
2016-04-12 |
2017-03-21 |
King Saud University |
Amino substituted acetamide derivative
|
WO2019094311A1
(en)
|
2017-11-08 |
2019-05-16 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
CN108299331A
(zh)
*
|
2018-03-02 |
2018-07-20 |
成都新恒创药业有限公司 |
一种帕瑞昔布钠光降解杂质及其制备、检测方法和应用
|
CN108164521B
(zh)
*
|
2018-03-02 |
2020-11-13 |
成都新恒创药业有限公司 |
一种帕瑞昔布钠降解杂质及其制备、检测方法和应用
|
EP3833667B1
(en)
|
2018-08-07 |
2024-03-13 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
US11993602B2
(en)
|
2018-08-07 |
2024-05-28 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
CN110305071A
(zh)
*
|
2019-07-23 |
2019-10-08 |
成都通德药业有限公司 |
一种帕瑞昔布钠中间体帕瑞昔布的合成方法
|
WO2021126731A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2022195579A1
(en)
|
2021-03-15 |
2022-09-22 |
Saul Yedgar |
Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases
|
CN115784991A
(zh)
*
|
2022-11-22 |
2023-03-14 |
合肥医工医药股份有限公司 |
N-(苯磺酰基)酰胺衍生物及其制备方法和用途
|