NO317989B1 - Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat - Google Patents
Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat Download PDFInfo
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- NO317989B1 NO317989B1 NO20005994A NO20005994A NO317989B1 NO 317989 B1 NO317989 B1 NO 317989B1 NO 20005994 A NO20005994 A NO 20005994A NO 20005994 A NO20005994 A NO 20005994A NO 317989 B1 NO317989 B1 NO 317989B1
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- pharmaceutical preparation
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- dipeptide
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823831A DE19823831A1 (de) | 1998-05-28 | 1998-05-28 | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
| PCT/EP1999/003712 WO1999061431A1 (fr) | 1998-05-28 | 1999-05-28 | Nouveaux effecteurs de dipeptidylpeptidase iv |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20005994D0 NO20005994D0 (no) | 2000-11-27 |
| NO20005994L NO20005994L (no) | 2001-01-25 |
| NO317989B1 true NO317989B1 (no) | 2005-01-17 |
Family
ID=7869159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005994A NO317989B1 (no) | 1998-05-28 | 2000-11-27 | Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US6548481B1 (fr) |
| EP (6) | EP1214936B1 (fr) |
| JP (1) | JP2002516318A (fr) |
| KR (2) | KR100628668B1 (fr) |
| CN (4) | CN101095675A (fr) |
| AT (6) | ATE272059T1 (fr) |
| AU (1) | AU764262B2 (fr) |
| BR (1) | BR9910758A (fr) |
| CA (1) | CA2333603C (fr) |
| DE (10) | DE19823831A1 (fr) |
| DK (2) | DK1304327T3 (fr) |
| ES (5) | ES2223981T3 (fr) |
| HK (3) | HK1033316A1 (fr) |
| HU (1) | HUP0102001A3 (fr) |
| IL (3) | IL139862A0 (fr) |
| IS (3) | IS5728A (fr) |
| NO (1) | NO317989B1 (fr) |
| NZ (2) | NZ508260A (fr) |
| PL (1) | PL344403A1 (fr) |
| PT (2) | PT1304327E (fr) |
| RU (3) | RU2309161C2 (fr) |
| SI (2) | SI1082314T1 (fr) |
| UA (1) | UA54599C2 (fr) |
| WO (1) | WO1999061431A1 (fr) |
Families Citing this family (242)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020006899A1 (en) * | 1998-10-06 | 2002-01-17 | Pospisilik Andrew J. | Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals |
| BR9813233A (pt) * | 1997-09-29 | 2000-08-22 | Point Therapeutics Inc | Estimulação de células hematopoéticas in vitro |
| DE19823831A1 (de) * | 1998-05-28 | 1999-12-02 | Probiodrug Ges Fuer Arzneim | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
| DE19828113A1 (de) | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
| DE19834591A1 (de) * | 1998-07-31 | 2000-02-03 | Probiodrug Ges Fuer Arzneim | Verfahren zur Steigerung des Blutglukosespiegels in Säugern |
| US6979697B1 (en) * | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
| US20030176357A1 (en) * | 1998-10-06 | 2003-09-18 | Pospisilik Andrew J. | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels |
| WO2000053171A1 (fr) * | 1999-03-05 | 2000-09-14 | Molteni L. E C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A. | Utilisation de metformine dans la preparation de compositions pharmaceutiques pouvant inhiber l'enzyme dipeptidyl peptidase iv |
| US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
| US6890904B1 (en) * | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
| DE19940130A1 (de) | 1999-08-24 | 2001-03-01 | Probiodrug Ges Fuer Arzneim | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| CA2393825A1 (fr) * | 1999-12-17 | 2001-06-21 | Versicor, Inc. | Nouveaux composes a base de succinate, compositions les contenant, et procedes d'utilisation et de preparation de ceux-ci |
| US20080076811A1 (en) * | 2000-01-21 | 2008-03-27 | Bork Balkan | Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents |
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| DE60137216D1 (de) * | 2000-03-31 | 2009-02-12 | Prosidion Ltd | Verbesserung der aktivität der inselzellen bei diabetes mellitus und dessen prävention |
| DE20220238U1 (de) * | 2002-02-28 | 2003-05-08 | Probiodrug AG, 06120 Halle | Glutaminyl basierte DPIV Inhibitoren |
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1998
- 1998-05-28 DE DE19823831A patent/DE19823831A1/de not_active Withdrawn
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1999
- 1999-05-28 DK DK03001324T patent/DK1304327T3/da active
- 1999-05-28 ES ES02005353T patent/ES2223981T3/es not_active Expired - Lifetime
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- 1999-05-28 DE DE59904100T patent/DE59904100D1/de not_active Expired - Lifetime
- 1999-05-28 WO PCT/EP1999/003712 patent/WO1999061431A1/fr active IP Right Grant
- 1999-05-28 AU AU43709/99A patent/AU764262B2/en not_active Ceased
- 1999-05-28 BR BR9910758-9A patent/BR9910758A/pt not_active Application Discontinuation
- 1999-05-28 CA CA002333603A patent/CA2333603C/fr not_active Expired - Fee Related
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- 1999-05-28 ES ES04005976T patent/ES2271723T3/es not_active Expired - Lifetime
- 1999-05-28 NZ NZ508260A patent/NZ508260A/xx unknown
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- 1999-05-28 CN CNA2007101369808A patent/CN101095675A/zh active Pending
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- 1999-05-28 EP EP02005353A patent/EP1214936B1/fr not_active Expired - Lifetime
- 1999-05-28 ES ES03026947T patent/ES2271458T3/es not_active Expired - Lifetime
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- 1999-05-28 DE DE59913784T patent/DE59913784D1/de not_active Expired - Fee Related
- 1999-05-28 CN CNA2004100833079A patent/CN1637018A/zh active Pending
- 1999-05-28 PT PT02005353T patent/PT1214936E/pt unknown
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- 1999-05-28 EP EP04005976A patent/EP1428533B1/fr not_active Expired - Lifetime
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- 1999-05-28 CN CNA2004100833064A patent/CN1636593A/zh active Pending
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- 1999-05-28 DK DK02005353T patent/DK1214936T3/da active
- 1999-05-28 EP EP02005352A patent/EP1215207B1/fr not_active Expired - Lifetime
- 1999-05-28 DE DE59911670T patent/DE59911670D1/de not_active Expired - Fee Related
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- 1999-05-28 JP JP2000550837A patent/JP2002516318A/ja active Pending
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2000
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2001
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2002
- 2002-12-06 HK HK02108901.9A patent/HK1047887B/zh not_active IP Right Cessation
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2003
- 2003-02-10 US US10/361,956 patent/US20030134802A1/en not_active Abandoned
- 2003-07-14 HK HK03105067.4A patent/HK1052708B/zh not_active IP Right Cessation
- 2003-12-02 US US10/727,209 patent/US20050203030A1/en not_active Abandoned
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2004
- 2004-01-15 RU RU2004101292/15A patent/RU2004101292A/ru not_active Application Discontinuation
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2005
- 2005-03-21 IS IS7764A patent/IS2130B/xx unknown
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2006
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