BR9813233A - Estimulação de células hematopoéticas in vitro - Google Patents

Estimulação de células hematopoéticas in vitro

Info

Publication number
BR9813233A
BR9813233A BR9813233-4A BR9813233A BR9813233A BR 9813233 A BR9813233 A BR 9813233A BR 9813233 A BR9813233 A BR 9813233A BR 9813233 A BR9813233 A BR 9813233A
Authority
BR
Brazil
Prior art keywords
vitro
hematopoietic cells
stimulation
methods
dipertidyl
Prior art date
Application number
BR9813233-4A
Other languages
English (en)
Inventor
William Bachovchin
Barbara P Wallner
Original Assignee
Point Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Point Therapeutics Inc filed Critical Point Therapeutics Inc
Publication of BR9813233A publication Critical patent/BR9813233A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

"ESTIMULAçãO DE CéLULAS HEMATOPOéTICAS IN VITRO" São proporcionados métodos, composições, e dispositivos para estimular o número e/ou a diferenciação de células hematopoéticas in vitro. Os métodos envolvem o contato das células hematopoéticas com um inibidor de dipertidil peptidase (DPIV) na ausência de citocinas proporcionadas de forma exógena.
BR9813233-4A 1997-09-29 1998-09-29 Estimulação de células hematopoéticas in vitro BR9813233A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6030697P 1997-09-29 1997-09-29
PCT/US1998/020343 WO1999016864A1 (en) 1997-09-29 1998-09-29 Stimulation of hematopoietic cells in vitro

Publications (1)

Publication Number Publication Date
BR9813233A true BR9813233A (pt) 2000-08-22

Family

ID=22028666

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813233-4A BR9813233A (pt) 1997-09-29 1998-09-29 Estimulação de células hematopoéticas in vitro

Country Status (16)

Country Link
US (3) US6258597B1 (pt)
EP (1) EP1019494B1 (pt)
JP (2) JP2001518290A (pt)
KR (1) KR100458403B1 (pt)
CN (1) CN1163594C (pt)
AT (1) ATE357509T1 (pt)
AU (1) AU743996B2 (pt)
BR (1) BR9813233A (pt)
CA (1) CA2304206A1 (pt)
DE (1) DE69837393T2 (pt)
ES (1) ES2285785T3 (pt)
IL (1) IL135068A (pt)
NO (1) NO20001583L (pt)
NZ (1) NZ503359A (pt)
TR (1) TR200000815T2 (pt)
WO (1) WO1999016864A1 (pt)

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US6258597B1 (en) 2001-07-10
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TR200000815T2 (tr) 2000-12-21
CN1272136A (zh) 2000-11-01
EP1019494B1 (en) 2007-03-21
NO20001583D0 (no) 2000-03-27
CN1163594C (zh) 2004-08-25
US7276371B2 (en) 2007-10-02
CA2304206A1 (en) 1999-04-08
DE69837393D1 (de) 2007-05-03
KR20010030775A (ko) 2001-04-16
US20010018210A1 (en) 2001-08-30
JP2001518290A (ja) 2001-10-16
AU9588798A (en) 1999-04-23
NO20001583L (no) 2000-05-29
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US6703238B2 (en) 2004-03-09
KR100458403B1 (ko) 2004-11-26
EP1019494A1 (en) 2000-07-19
ATE357509T1 (de) 2007-04-15
WO1999016864A1 (en) 1999-04-08
JP2006081554A (ja) 2006-03-30
IL135068A (en) 2004-03-28
AU743996B2 (en) 2002-02-14
IL135068A0 (en) 2001-05-20
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US20040152192A1 (en) 2004-08-05

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