NO20083756L - Fremgangsmate for fremstilling av escitalopram - Google Patents

Fremgangsmate for fremstilling av escitalopram

Info

Publication number
NO20083756L
NO20083756L NO20083756A NO20083756A NO20083756L NO 20083756 L NO20083756 L NO 20083756L NO 20083756 A NO20083756 A NO 20083756A NO 20083756 A NO20083756 A NO 20083756A NO 20083756 L NO20083756 L NO 20083756L
Authority
NO
Norway
Prior art keywords
escitalopram
procedure
preparation
benzonitrile
hydroxybutyl
Prior art date
Application number
NO20083756A
Other languages
English (en)
Norwegian (no)
Inventor
Carla De Faveri
Florian Anton Martin Huber
Robert James Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735675&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20083756(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20083756L publication Critical patent/NO20083756L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
NO20083756A 2007-09-11 2008-09-01 Fremgangsmate for fremstilling av escitalopram NO20083756L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200701314 2007-09-11

Publications (1)

Publication Number Publication Date
NO20083756L true NO20083756L (no) 2009-03-12

Family

ID=39735675

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083756A NO20083756L (no) 2007-09-11 2008-09-01 Fremgangsmate for fremstilling av escitalopram

Country Status (52)

Country Link
EP (2) EP2397461A1 (et)
JP (1) JP4966933B2 (et)
KR (1) KR101054224B1 (et)
CN (1) CN101386583A (et)
AR (2) AR068174A1 (et)
AT (2) ATE518829T1 (et)
AU (1) AU2008212055C1 (et)
BE (1) BE1017548A6 (et)
BG (1) BG110206A (et)
BR (1) BRPI0804121B1 (et)
CA (1) CA2638499C (et)
CH (1) CH697885B1 (et)
CL (1) CL2008002686A1 (et)
CO (1) CO6140012A1 (et)
CY (2) CY2600B1 (et)
CZ (1) CZ2008537A3 (et)
DE (1) DE102008046530A1 (et)
DK (2) DK2061753T3 (et)
EA (1) EA012787B1 (et)
EE (1) EE00864U1 (et)
ES (2) ES2368294T3 (et)
FI (1) FI121570B (et)
FR (1) FR2920766A1 (et)
GB (1) GB2448848B (et)
GR (1) GR1006595B (et)
HR (2) HRP20080425A2 (et)
HU (1) HUP0800549A2 (et)
IE (1) IES20080708A2 (et)
IL (1) IL193845A (et)
IS (1) IS8758A (et)
LT (1) LT5577B (et)
LU (1) LU91479B1 (et)
LV (1) LV13813B (et)
ME (1) ME00176B (et)
MX (1) MX2008011451A (et)
MY (1) MY144210A (et)
NL (1) NL2001953C2 (et)
NO (1) NO20083756L (et)
NZ (1) NZ570884A (et)
PL (2) PL386026A1 (et)
PT (2) PT104169A (et)
RO (1) RO125301A2 (et)
RS (2) RS20080401A (et)
SE (1) SE533041C2 (et)
SG (1) SG151195A1 (et)
SI (2) SI22567A2 (et)
SK (1) SK500302008A3 (et)
TR (2) TR200806903A2 (et)
TW (1) TWI391383B (et)
UA (2) UA41919U (et)
WO (1) WO2009033488A1 (et)
ZA (1) ZA200807753B (et)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007012954A1 (en) 2005-07-27 2007-02-01 Aurobindo Pharma Limited An improved process for the preparation of escitalopram
CN102796065A (zh) * 2011-05-27 2012-11-28 江苏豪森医药集团连云港宏创医药有限公司 一种制备光学纯度高的艾司西酞普兰的方法
CN104119240A (zh) * 2013-04-23 2014-10-29 中国人民解放军军事医学科学院毒物药物研究所 (S)-(-)-α-甲胺基苯丙酮的制备方法
CN103497145B (zh) * 2013-10-10 2016-01-27 南昌大学 一种光学纯多奈哌齐的制备工艺
CN104119248A (zh) * 2014-08-08 2014-10-29 广东东阳光药业有限公司 S-西酞普兰的制备方法
US10287240B2 (en) 2014-11-14 2019-05-14 Zhejiang Hushai Pharmaceuticals Co., Ltd. Method for resolution of citalopram intermediate 5-cyano diol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
AR034612A1 (es) 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) * 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
CA2511143C (en) 2002-12-23 2011-06-28 H. Lundbeck A/S Preparation of racemic and/or s- or r-citalopram diols and their use for the preparation racemic and/or s- or r-citalopram
WO2004065375A1 (en) * 2003-01-17 2004-08-05 Natco Pharma Limited Processes for the preparation of escitalopram and its precursor
WO2005047274A1 (en) * 2003-11-12 2005-05-26 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
WO2006106531A1 (en) * 2005-04-04 2006-10-12 Jubilant Organosys Ltd Process for the preparation of escitalopram or its acid addition salts
WO2007012954A1 (en) * 2005-07-27 2007-02-01 Aurobindo Pharma Limited An improved process for the preparation of escitalopram

Also Published As

Publication number Publication date
SI22567A2 (sl) 2008-12-31
ES2334875A1 (es) 2010-03-16
HRP20110636T1 (hr) 2011-10-31
PT2061753E (pt) 2011-09-14
RS20080401A (en) 2010-03-02
PT104169A (pt) 2009-02-02
RO125301A2 (ro) 2010-03-30
ZA200807753B (en) 2009-04-29
FI20085807A (fi) 2009-03-12
AT10984U1 (de) 2010-02-15
KR101054224B1 (ko) 2011-08-08
EP2397461A1 (en) 2011-12-21
EP2061753A1 (en) 2009-05-27
GR20080100581A (el) 2009-04-30
TR200806903A2 (tr) 2009-03-23
DK2061753T3 (da) 2011-09-26
LT2008068A (en) 2009-03-25
LT5577B (lt) 2009-06-25
JP2009149600A (ja) 2009-07-09
RS51909B (en) 2012-02-29
FI20085807A0 (fi) 2008-08-29
SI2061753T1 (sl) 2011-10-28
BRPI0804121A8 (pt) 2021-04-13
GB0815773D0 (en) 2008-10-08
MEP10108A (en) 2010-10-10
CZ2008537A3 (cs) 2009-03-18
GB2448848B (en) 2011-01-26
CA2638499C (en) 2010-09-28
TW200906814A (en) 2009-02-16
WO2009033488A1 (en) 2009-03-19
BG110206A (en) 2009-03-31
HU0800549D0 (en) 2008-10-28
MY144210A (en) 2011-08-15
JP4966933B2 (ja) 2012-07-04
GR1006595B (el) 2009-11-16
NL2001953A1 (nl) 2008-12-22
AR108885A2 (es) 2018-10-03
NZ570884A (en) 2010-03-26
UA41919U (uk) 2009-06-10
EA200801797A2 (ru) 2008-12-30
IES20080708A2 (en) 2009-03-18
HUP0800549A2 (en) 2009-03-02
AR068174A1 (es) 2009-11-11
GB2448848A (en) 2008-10-29
ES2368294T3 (es) 2011-11-16
EP2061753B1 (en) 2011-08-03
LU91479B1 (fr) 2010-03-11
SG151195A1 (en) 2009-04-30
AU2008212055C1 (en) 2011-06-02
DK200801265A (en) 2009-03-12
AU2008212055A1 (en) 2009-03-26
PL386026A1 (pl) 2009-02-16
CA2638499A1 (en) 2008-11-21
PL2061753T3 (pl) 2011-12-30
EE00864U1 (et) 2009-10-15
SE533041C2 (sv) 2010-06-15
AU2008212055B2 (en) 2010-08-12
ME00176B (me) 2011-02-10
SE0801929L (sv) 2009-03-12
ATE518829T1 (de) 2011-08-15
EA012787B1 (ru) 2009-12-30
LV13813B (en) 2008-11-20
EA200801797A3 (ru) 2009-02-27
HRP20080425A2 (hr) 2010-04-30
IS8758A (is) 2009-03-12
CO6140012A1 (es) 2010-03-19
CY2600B1 (en) 2010-03-03
BRPI0804121B1 (pt) 2022-04-12
ES2334875B1 (es) 2010-10-27
CN101386583A (zh) 2009-03-18
IL193845A (en) 2011-03-31
DE102008046530A1 (de) 2009-03-19
BE1017548A6 (fr) 2008-11-04
DK177075B1 (da) 2011-06-14
CL2008002686A1 (es) 2009-01-02
TWI391383B (zh) 2013-04-01
TR200907629A2 (tr) 2009-11-23
SK500302008A3 (sk) 2009-04-06
NL2001953C2 (en) 2009-05-07
KR20090027185A (ko) 2009-03-16
CY1111924T1 (el) 2015-11-04
UA43461U (uk) 2009-08-25
BRPI0804121A2 (pt) 2009-09-29
MX2008011451A (es) 2009-03-10
FR2920766A1 (fr) 2009-03-13
FI121570B (fi) 2011-01-14
CH697885B1 (de) 2009-03-13

Similar Documents

Publication Publication Date Title
NO20083756L (no) Fremgangsmate for fremstilling av escitalopram
MX2007012883A (es) Derivados de dihidrobenzofurano y usos de los mismos.
TW200719886A (en) Dihydrobenzofuran derivatives and uses thereof
RS51341B (en) INTERMEDIATE COMPOUNDS FOR THE TRANS-5-CHLOR-2-METHYL-2,3A, 12B-TETRAHYDRO-1H-DIBENZE [2,3; 6,7] OXEPINO [4,5-C] Pyrrole
NO20075385L (no) 7-aminoalkylidenyl-heterocykliske kinoloner og naftyridoner
DE602005017194D1 (de) Verfahren zur herstellung von carvedilol und seinen enantiomeren
WO2008059514A3 (en) Process for preparing escitalopram
DK1740571T3 (da) Fremgangsmåde til fremstilling af pyridinylmethyl-1H-benzimidazolforbindelser i enantiomerisk beriget form eller som enkelte enantiomerer
DK1893589T3 (da) Substituerede N-benzo[d]isoxazol-3-yl-amin-derivater som inhibitorer af mGluR5-, serotonin-(5-HT) og noradrenalinreceptorer og deres anvendelse til fremstilling af lægemidler
RU2006140988A (ru) Фармацевтические композиции, содержащие соль миртазапина
DE602006014001D1 (de) Herstellung von 2-aminothiazol-5-carbonsäurederivaten
ES2285972T1 (es) Procedimiento de fabricacion de citalopram y enantiomeros.
BRPI0508808A (pt) processo quimio-enzimático para preparar escitalopram
WO2007123942A3 (en) Benzodioxane and benzodioxolane derivatives and uses thereof
ATE387423T1 (de) Verfahren zur herstellung der enantiomeren formen von 2,3-diaminopropionsäurederivaten
DK1988086T3 (da) Fremgangsmåde til opløsning af citalopram via dets (S)-berigede citalopramtartratforbindelse
NO20066003L (no) Fremgangsmate for fremstillingen av pyridin-2-ylmetylsulfinyl-lH-benzimidazolforbindelser
WO2006127331A3 (en) Conversion process for 2,3-benzodiazepine enantiomers
TH91931B (th) การใช้แบบใหม่ของเอสซิแทลอแพรม
TH106299B (th) เฟนิลพิเพอราซีนชนิดใหม่
TH78463B (th) กรรมวิธีสำหรับการเตรียมไครัล 8-(3-อะมิโนไพเพอริดิน-1-อิล)-แซนธีน
TH91931A (th) การใช้แบบใหม่ของเอสซิแทลอแพรม
TH93357B (th) อะมิโน-อิมิดาโซลีน และการใช้สารเหล่านี้เป็นยาสำหรับการรักษาโรคความผิดปกติที่เกี่ยวเนื่องกับการรับรู้บกพร่อง, โรคอัลไซเมอร์, การเสื่อมของประสาท และภาวะสมองเสื่อม