DE602006014001D1 - Herstellung von 2-aminothiazol-5-carbonsäurederivaten - Google Patents
Herstellung von 2-aminothiazol-5-carbonsäurederivatenInfo
- Publication number
- DE602006014001D1 DE602006014001D1 DE602006014001T DE602006014001T DE602006014001D1 DE 602006014001 D1 DE602006014001 D1 DE 602006014001D1 DE 602006014001 T DE602006014001 T DE 602006014001T DE 602006014001 T DE602006014001 T DE 602006014001T DE 602006014001 D1 DE602006014001 D1 DE 602006014001D1
- Authority
- DE
- Germany
- Prior art keywords
- aminothiazole
- preparation
- carboxylic acid
- acid derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05107247 | 2005-08-05 | ||
| EP05107375 | 2005-08-11 | ||
| PCT/US2006/030198 WO2007019210A1 (en) | 2005-08-05 | 2006-08-03 | Preparation of 2-amino-thiazole-5-carboxylic-acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006014001D1 true DE602006014001D1 (de) | 2010-06-10 |
Family
ID=37487962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006014001T Active DE602006014001D1 (de) | 2005-08-05 | 2006-08-03 | Herstellung von 2-aminothiazol-5-carbonsäurederivaten |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7408069B2 (de) |
| EP (1) | EP1919885B1 (de) |
| AT (1) | ATE466003T1 (de) |
| DE (1) | DE602006014001D1 (de) |
| ES (1) | ES2342194T3 (de) |
| WO (1) | WO2007019210A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE466003T1 (de) * | 2005-08-05 | 2010-05-15 | Bristol Myers Squibb Co | Herstellung von 2-aminothiazol-5- carbonsäurederivaten |
| ES2565521T5 (es) * | 2007-10-23 | 2019-12-10 | Teva Pharma | Polimorfos de dasatinib y proceso para la preparación de los mismos |
| US9365526B2 (en) | 2012-12-31 | 2016-06-14 | Sun Pharmaceutical Industries Limited | Process for the preparation of dasatinib and its intermediates |
| CN104119292A (zh) * | 2014-07-23 | 2014-10-29 | 天津市炜杰科技有限公司 | 一种达沙替尼中间体的制备方法 |
| CN116808044A (zh) | 2018-06-15 | 2023-09-29 | 汉达癌症医药责任有限公司 | 激酶抑制剂的盐类及其组合物 |
| WO2020092650A1 (en) * | 2018-10-30 | 2020-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating t cell exhaustion |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH1122773A4 (de) | 1973-08-02 | 1975-02-14 | ||
| JPS6339868A (ja) * | 1986-08-04 | 1988-02-20 | Otsuka Pharmaceut Factory Inc | ジ低級アルキルフエノ−ル誘導体 |
| WO2000062778A1 (en) * | 1999-04-15 | 2000-10-26 | Bristol-Myers Squibb Co. | Cyclic protein tyrosine kinase inhibitors |
| JP2002338537A (ja) | 2001-05-16 | 2002-11-27 | Mitsubishi Pharma Corp | アミド化合物およびその医薬用途 |
| CN100357283C (zh) | 2002-04-02 | 2007-12-26 | 中国科学院上海药物研究所 | 一类甲硫氨酰氨肽酶抑制剂 |
| BRPI0407283A (pt) | 2003-02-13 | 2006-01-31 | Banyu Pharma Co Ltd | Composto, composição farmacêutica, e, agente ativador de glucoquinase, agentes terapêuticos e/ou agentes preventivos para diabetes melito e obesidade |
| TWI338004B (en) * | 2004-02-06 | 2011-03-01 | Bristol Myers Squibb Co | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| US20050215795A1 (en) * | 2004-02-06 | 2005-09-29 | Bang-Chi Chen | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| US7491725B2 (en) * | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| ATE466003T1 (de) * | 2005-08-05 | 2010-05-15 | Bristol Myers Squibb Co | Herstellung von 2-aminothiazol-5- carbonsäurederivaten |
-
2006
- 2006-08-03 AT AT06789255T patent/ATE466003T1/de not_active IP Right Cessation
- 2006-08-03 EP EP06789255A patent/EP1919885B1/de active Active
- 2006-08-03 WO PCT/US2006/030198 patent/WO2007019210A1/en active Application Filing
- 2006-08-03 DE DE602006014001T patent/DE602006014001D1/de active Active
- 2006-08-03 US US11/498,650 patent/US7408069B2/en active Active
- 2006-08-03 ES ES06789255T patent/ES2342194T3/es active Active
-
2008
- 2008-07-02 US US12/166,410 patent/US7932386B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US7408069B2 (en) | 2008-08-05 |
| US20070037978A1 (en) | 2007-02-15 |
| ATE466003T1 (de) | 2010-05-15 |
| EP1919885B1 (de) | 2010-04-28 |
| US20090030203A1 (en) | 2009-01-29 |
| ES2342194T3 (es) | 2010-07-02 |
| US7932386B2 (en) | 2011-04-26 |
| WO2007019210A1 (en) | 2007-02-15 |
| EP1919885A1 (de) | 2008-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |