DE602005017194D1 - Verfahren zur herstellung von carvedilol und seinen enantiomeren - Google Patents
Verfahren zur herstellung von carvedilol und seinen enantiomerenInfo
- Publication number
- DE602005017194D1 DE602005017194D1 DE602005017194T DE602005017194T DE602005017194D1 DE 602005017194 D1 DE602005017194 D1 DE 602005017194D1 DE 602005017194 T DE602005017194 T DE 602005017194T DE 602005017194 T DE602005017194 T DE 602005017194T DE 602005017194 D1 DE602005017194 D1 DE 602005017194D1
- Authority
- DE
- Germany
- Prior art keywords
- carvedilol
- preparation
- enantiomer
- enantiomers
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04106438 | 2004-12-09 | ||
| PCT/EP2005/056469 WO2006061364A1 (en) | 2004-12-09 | 2005-12-05 | Process for the preparation of carvedilol and its enantiomers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005017194D1 true DE602005017194D1 (de) | 2009-11-26 |
Family
ID=35985349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005017194T Active DE602005017194D1 (de) | 2004-12-09 | 2005-12-05 | Verfahren zur herstellung von carvedilol und seinen enantiomeren |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20090005429A1 (de) |
| EP (1) | EP1838670B1 (de) |
| JP (1) | JP2008523025A (de) |
| CN (1) | CN100591668C (de) |
| AT (1) | ATE445601T1 (de) |
| CA (1) | CA2589699A1 (de) |
| CY (1) | CY1110688T1 (de) |
| DE (1) | DE602005017194D1 (de) |
| DK (1) | DK1838670T3 (de) |
| ES (1) | ES2333537T3 (de) |
| HR (1) | HRP20100023T1 (de) |
| IL (1) | IL183449A0 (de) |
| PL (1) | PL1838670T3 (de) |
| PT (1) | PT1838670E (de) |
| SI (1) | SI1838670T1 (de) |
| WO (1) | WO2006061364A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000216A1 (en) | 2000-06-28 | 2002-01-03 | Teva Pharmaceutical Industries Ltd. | Carvedilol |
| US6710184B2 (en) | 2002-01-15 | 2004-03-23 | Teva Pharmaceutical Industries Ltd. | Crystalline solids of carvedilol and processes for their preparation |
| KR100746455B1 (ko) * | 2006-02-23 | 2007-08-03 | 안국약품 주식회사 | 고광학순도의 키랄 카베딜롤의 제조방법 |
| US8022094B2 (en) | 2006-06-28 | 2011-09-20 | Teva Pharmaceutical Industries Ltd. | Carvedilol phosphate |
| CN102190613B (zh) * | 2010-03-14 | 2014-06-25 | 浙江华海药业股份有限公司 | 一种卡维地洛的制备方法 |
| DK2549871T3 (en) | 2010-03-23 | 2018-12-10 | Siga Tech Inc | Polymorphic form ST-246 and processes for its preparation |
| WO2015031914A1 (en) * | 2013-08-30 | 2015-03-05 | Uti Limited Partnership | Store overload-induced calcium release inhibitors and methods for producing and using the same |
| CN104592096A (zh) * | 2014-12-24 | 2015-05-06 | 江苏苏南药业实业有限公司 | 一种s-卡维地洛的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3319027A1 (de) * | 1983-05-26 | 1984-11-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten |
| EP0893440A1 (de) * | 1997-07-22 | 1999-01-27 | Roche Diagnostics GmbH | Eine thermodynamisch stabile Modifikation von 1-(4-Carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]- 2-propanole, Verfahren zu ihrer Herstellung und ihre enthaltende Arznemittel |
| WO2002000216A1 (en) * | 2000-06-28 | 2002-01-03 | Teva Pharmaceutical Industries Ltd. | Carvedilol |
-
2005
- 2005-12-05 WO PCT/EP2005/056469 patent/WO2006061364A1/en active Application Filing
- 2005-12-05 DE DE602005017194T patent/DE602005017194D1/de active Active
- 2005-12-05 PL PL05815876T patent/PL1838670T3/pl unknown
- 2005-12-05 PT PT05815876T patent/PT1838670E/pt unknown
- 2005-12-05 ES ES05815876T patent/ES2333537T3/es active Active
- 2005-12-05 DK DK05815876.7T patent/DK1838670T3/da active
- 2005-12-05 CA CA002589699A patent/CA2589699A1/en not_active Abandoned
- 2005-12-05 JP JP2007544890A patent/JP2008523025A/ja active Pending
- 2005-12-05 EP EP05815876A patent/EP1838670B1/de active Active
- 2005-12-05 US US11/720,110 patent/US20090005429A1/en not_active Abandoned
- 2005-12-05 AT AT05815876T patent/ATE445601T1/de active
- 2005-12-05 CN CN200580042214A patent/CN100591668C/zh not_active Expired - Fee Related
- 2005-12-05 SI SI200530863T patent/SI1838670T1/sl unknown
-
2007
- 2007-05-28 IL IL183449A patent/IL183449A0/en unknown
-
2009
- 2009-12-08 CY CY20091101281T patent/CY1110688T1/el unknown
-
2010
- 2010-01-13 HR HR20100023T patent/HRP20100023T1/hr unknown
-
2011
- 2011-10-27 US US13/282,868 patent/US20120041044A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL1838670T3 (pl) | 2010-03-31 |
| CY1110688T1 (el) | 2015-06-10 |
| US20120041044A1 (en) | 2012-02-16 |
| CA2589699A1 (en) | 2006-06-15 |
| CN101072753A (zh) | 2007-11-14 |
| HRP20100023T1 (hr) | 2010-02-28 |
| EP1838670B1 (de) | 2009-10-14 |
| EP1838670A1 (de) | 2007-10-03 |
| US20090005429A1 (en) | 2009-01-01 |
| WO2006061364A1 (en) | 2006-06-15 |
| SI1838670T1 (sl) | 2010-04-30 |
| CN100591668C (zh) | 2010-02-24 |
| IL183449A0 (en) | 2007-09-20 |
| JP2008523025A (ja) | 2008-07-03 |
| ES2333537T3 (es) | 2010-02-23 |
| PT1838670E (pt) | 2009-12-18 |
| ATE445601T1 (de) | 2009-10-15 |
| DK1838670T3 (da) | 2010-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |