NO20025091L - Oksazolidinonderivater med antibiotisk aktivitet - Google Patents

Oksazolidinonderivater med antibiotisk aktivitet

Info

Publication number
NO20025091L
NO20025091L NO20025091A NO20025091A NO20025091L NO 20025091 L NO20025091 L NO 20025091L NO 20025091 A NO20025091 A NO 20025091A NO 20025091 A NO20025091 A NO 20025091A NO 20025091 L NO20025091 L NO 20025091L
Authority
NO
Norway
Prior art keywords
alkyl
optionally substituted
atom
het
compounds
Prior art date
Application number
NO20025091A
Other languages
English (en)
Other versions
NO328549B1 (no
NO20025091D0 (no
Inventor
Michael Barry Gravestock
Michael John Betts
David Alan Griffin
Ian Richard Matthews
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9890314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20025091(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20025091D0 publication Critical patent/NO20025091D0/no
Publication of NO20025091L publication Critical patent/NO20025091L/no
Publication of NO328549B1 publication Critical patent/NO328549B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oksazoldinonderivater med formel (I), eller et farmasøytisk tålbart salt eller en in-vivo-hydrolyserbar ester derav, hvori HET er en tilknyttet femleddet heteroarylring, eventuelt substituert på et C-atom med en okso- eller tioksogruppe; og/eller med 1 eller 2(1-4C)alkylgrupper; og/eller på et tilgjengelig nitrogenatom med (l-4C)alkyl; eller HET er en tilknyttet 6-leddet heteroarylring inneholdende opptil tre nitrogenheteroatomer totalt, eventuelt substituert på et C-atom som ovenfor; Q er valgt fra for eksempel (Ql), Rog Rer uavhengig hydrogen eller fluor; T er valgt fra et område av grupper, for eksempel med formel (TC5), hvori Rc for eksempel er RCO-, RS0- eller RCS-; hvori Rfor eksempel er eventuelt substituert (l-lOC)alkyl eller RC(0)0(l-6C)alkyl hvori1er eventuelt substituert (l-lOC)alkyl; hvor forbindelsene er nyttige som antibakterielle midler; og fremgangsmåter for deres fremstilling og farmasøytiske blandinger inneholdende forbindelsene, er beskrevet.
NO20025091A 2000-04-25 2002-10-23 Oksazolidinonderivater med antibiotisk aktivitet NO328549B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0009803.8A GB0009803D0 (en) 2000-04-25 2000-04-25 Chemical compounds
PCT/GB2001/001815 WO2001081350A1 (en) 2000-04-25 2001-04-23 Oxazolidinone derivatives with antibiotic activity

Publications (3)

Publication Number Publication Date
NO20025091D0 NO20025091D0 (no) 2002-10-23
NO20025091L true NO20025091L (no) 2002-12-09
NO328549B1 NO328549B1 (no) 2010-03-15

Family

ID=9890314

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025091A NO328549B1 (no) 2000-04-25 2002-10-23 Oksazolidinonderivater med antibiotisk aktivitet

Country Status (29)

Country Link
US (1) US7141583B2 (no)
EP (1) EP1286998B2 (no)
JP (1) JP2003531211A (no)
KR (1) KR100858771B1 (no)
CN (1) CN1277829C (no)
AT (1) ATE268778T1 (no)
AU (1) AU781784B2 (no)
BR (1) BR0110240A (no)
CA (1) CA2405349C (no)
CZ (1) CZ20023527A3 (no)
DE (1) DE60103754T3 (no)
DK (1) DK1286998T4 (no)
EE (1) EE200200598A (no)
ES (1) ES2220759T5 (no)
GB (1) GB0009803D0 (no)
HK (1) HK1053114A1 (no)
HU (1) HUP0300416A2 (no)
IL (2) IL152284A0 (no)
IS (1) IS6583A (no)
MX (1) MXPA02010453A (no)
NO (1) NO328549B1 (no)
NZ (1) NZ521765A (no)
PL (1) PL358326A1 (no)
PT (1) PT1286998E (no)
RU (1) RU2002131455A (no)
SI (1) SI1286998T2 (no)
TR (1) TR200402261T4 (no)
WO (1) WO2001081350A1 (no)
ZA (1) ZA200208187B (no)

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SI1286998T1 (en) 2004-10-31
MXPA02010453A (es) 2003-04-25
US7141583B2 (en) 2006-11-28
ATE268778T1 (de) 2004-06-15
KR100858771B1 (ko) 2008-09-16
TR200402261T4 (tr) 2004-12-21
US20030216373A1 (en) 2003-11-20
HUP0300416A2 (hu) 2003-06-28
ES2220759T3 (es) 2004-12-16
PL358326A1 (en) 2004-08-09
RU2002131455A (ru) 2004-03-27
CN1277829C (zh) 2006-10-04
DE60103754D1 (de) 2004-07-15
BR0110240A (pt) 2003-01-07
SI1286998T2 (sl) 2008-04-30
AU4863601A (en) 2001-11-07
CZ20023527A3 (cs) 2003-01-15
DE60103754T2 (de) 2005-06-16
ES2220759T5 (es) 2008-04-16
DK1286998T4 (da) 2008-03-10
EP1286998B1 (en) 2004-06-09
HK1053114A1 (en) 2003-10-10
IL152284A0 (en) 2003-05-29
NZ521765A (en) 2004-05-28
EP1286998B2 (en) 2007-10-31
NO328549B1 (no) 2010-03-15
AU781784B2 (en) 2005-06-16
EP1286998A1 (en) 2003-03-05
ZA200208187B (en) 2004-02-11
CA2405349C (en) 2011-08-02
NO20025091D0 (no) 2002-10-23
EE200200598A (et) 2004-04-15
GB0009803D0 (en) 2000-06-07
WO2001081350A1 (en) 2001-11-01
DK1286998T3 (da) 2004-09-06
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JP2003531211A (ja) 2003-10-21
DE60103754T3 (de) 2008-06-05
CN1437603A (zh) 2003-08-20
IS6583A (is) 2002-10-16
PT1286998E (pt) 2004-09-30
IL152284A (en) 2010-05-31

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