DK1286998T3 - Oxazolidinonderivater med antibiotisk aktivitet - Google Patents

Oxazolidinonderivater med antibiotisk aktivitet

Info

Publication number
DK1286998T3
DK1286998T3 DK01921669T DK01921669T DK1286998T3 DK 1286998 T3 DK1286998 T3 DK 1286998T3 DK 01921669 T DK01921669 T DK 01921669T DK 01921669 T DK01921669 T DK 01921669T DK 1286998 T3 DK1286998 T3 DK 1286998T3
Authority
DK
Denmark
Prior art keywords
sup
alkyl
optionally substituted
atom
het
Prior art date
Application number
DK01921669T
Other languages
English (en)
Other versions
DK1286998T4 (da
Inventor
Michael John Betts
Michael Barry Gravestock
David Alan Griffin
Ian Richard Matthews
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9890314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1286998(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1286998T3 publication Critical patent/DK1286998T3/da
Publication of DK1286998T4 publication Critical patent/DK1286998T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK01921669T 2000-04-25 2001-04-23 Oxazolidinonderivater med antibiotisk aktivitet DK1286998T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0009803.8A GB0009803D0 (en) 2000-04-25 2000-04-25 Chemical compounds
PCT/GB2001/001815 WO2001081350A1 (en) 2000-04-25 2001-04-23 Oxazolidinone derivatives with antibiotic activity

Publications (2)

Publication Number Publication Date
DK1286998T3 true DK1286998T3 (da) 2004-09-06
DK1286998T4 DK1286998T4 (da) 2008-03-10

Family

ID=9890314

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01921669T DK1286998T4 (da) 2000-04-25 2001-04-23 Oxazolidinonderivater med antibiotisk aktivitet

Country Status (29)

Country Link
US (1) US7141583B2 (da)
EP (1) EP1286998B2 (da)
JP (1) JP2003531211A (da)
KR (1) KR100858771B1 (da)
CN (1) CN1277829C (da)
AT (1) ATE268778T1 (da)
AU (1) AU781784B2 (da)
BR (1) BR0110240A (da)
CA (1) CA2405349C (da)
CZ (1) CZ20023527A3 (da)
DE (1) DE60103754T3 (da)
DK (1) DK1286998T4 (da)
EE (1) EE200200598A (da)
ES (1) ES2220759T5 (da)
GB (1) GB0009803D0 (da)
HK (1) HK1053114A1 (da)
HU (1) HUP0300416A2 (da)
IL (2) IL152284A0 (da)
IS (1) IS6583A (da)
MX (1) MXPA02010453A (da)
NO (1) NO328549B1 (da)
NZ (1) NZ521765A (da)
PL (1) PL358326A1 (da)
PT (1) PT1286998E (da)
RU (1) RU2002131455A (da)
SI (1) SI1286998T2 (da)
TR (1) TR200402261T4 (da)
WO (1) WO2001081350A1 (da)
ZA (1) ZA200208187B (da)

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EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
KR100445437B1 (ko) * 2002-02-08 2004-08-21 한국과학기술연구원 네오마이신-옥사졸리디논 헤테로 이합체, 그의 제조방법및 그의 용도
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7473699B2 (en) * 2002-02-28 2009-01-06 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents
EP1480975A2 (en) * 2002-02-28 2004-12-01 Astrazeneca AB Chemical compounds
US7094900B2 (en) 2002-08-12 2006-08-22 Pharmacia & Upjohn Company Llc N-Aryl-2-oxazolidinones and their derivatives
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US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
EP1565186B1 (en) 2002-11-21 2006-11-02 Pharmacia & Upjohn Company LLC N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
US7498350B2 (en) 2002-11-28 2009-03-03 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0227701D0 (en) * 2002-11-28 2003-01-08 Astrazeneca Ab Chemical compounds
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JP5383037B2 (ja) 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
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SI1286998T1 (en) 2004-10-31
MXPA02010453A (es) 2003-04-25
US7141583B2 (en) 2006-11-28
ATE268778T1 (de) 2004-06-15
KR100858771B1 (ko) 2008-09-16
TR200402261T4 (tr) 2004-12-21
US20030216373A1 (en) 2003-11-20
HUP0300416A2 (hu) 2003-06-28
ES2220759T3 (es) 2004-12-16
PL358326A1 (en) 2004-08-09
RU2002131455A (ru) 2004-03-27
CN1277829C (zh) 2006-10-04
DE60103754D1 (de) 2004-07-15
BR0110240A (pt) 2003-01-07
SI1286998T2 (sl) 2008-04-30
NO20025091L (no) 2002-12-09
AU4863601A (en) 2001-11-07
CZ20023527A3 (cs) 2003-01-15
DE60103754T2 (de) 2005-06-16
ES2220759T5 (es) 2008-04-16
DK1286998T4 (da) 2008-03-10
EP1286998B1 (en) 2004-06-09
HK1053114A1 (en) 2003-10-10
IL152284A0 (en) 2003-05-29
NZ521765A (en) 2004-05-28
EP1286998B2 (en) 2007-10-31
NO328549B1 (no) 2010-03-15
AU781784B2 (en) 2005-06-16
EP1286998A1 (en) 2003-03-05
ZA200208187B (en) 2004-02-11
CA2405349C (en) 2011-08-02
NO20025091D0 (no) 2002-10-23
EE200200598A (et) 2004-04-15
GB0009803D0 (en) 2000-06-07
WO2001081350A1 (en) 2001-11-01
CA2405349A1 (en) 2001-11-01
JP2003531211A (ja) 2003-10-21
DE60103754T3 (de) 2008-06-05
CN1437603A (zh) 2003-08-20
IS6583A (is) 2002-10-16
PT1286998E (pt) 2004-09-30
IL152284A (en) 2010-05-31

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