NO922028L - Azol-derivater - Google Patents

Azol-derivater

Info

Publication number
NO922028L
NO922028L NO92922028A NO922028A NO922028L NO 922028 L NO922028 L NO 922028L NO 92922028 A NO92922028 A NO 92922028A NO 922028 A NO922028 A NO 922028A NO 922028 L NO922028 L NO 922028L
Authority
NO
Norway
Prior art keywords
alkyl
phenyl
unsubstituted
substituted
oxygen
Prior art date
Application number
NO92922028A
Other languages
English (en)
Other versions
NO922028D0 (no
Inventor
Peter William Rodney Caulkett
Geraint Jones
Simon Martin Poucher
Michael George Collis
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of NO922028D0 publication Critical patent/NO922028D0/no
Publication of NO922028L publication Critical patent/NO922028L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Forbindelse med formel I N hvor: R1 er hydrogen, (l-6C)alkyl eller (l-4C)alkanoyl; R2 er fenyl, en C-bundet aromatisk 5- eller 6-leddet heterocyklisk ring som inneholder enten ett oksygen- eller ett svovelatom og/eller ett eller to nitrogenatomer, eller (l-8C)alkyl, -alkenyl eller -alkynyl, usubstituert eller substituert med en fenyl- eller C-bundet aromatisk 5- eller 6- leddet heterocyklisk ring som inneholder enten ett oksygen- eller ett svovelatom og/eller ett eller to nitrogenatomer, hvor enhver fenylgruppe kan være usubstituert eller substituert med en, to eller tre (l-4C)alkyl, (l-4C)alkoksy, halogen, trifluormetyl, hydroksy, benzyloksy og (1- 5C)alkanoyloksy; A er N eller CT, hvor T er hydrogen eller (l-4C)alkyl; eller et farmasøytisk akseptabelt salt derav. 7remgangsmåter for fremstilling av forbindelsene og farmasaytiske preparatar som inneholder disse, er beskrevet. Forbindelsene er anvendelige som adenosin-antagonister.
NO92922028A 1991-05-23 1992-05-22 Azol-derivater NO922028L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111130A GB9111130D0 (en) 1991-05-23 1991-05-23 Azole derivatives

Publications (2)

Publication Number Publication Date
NO922028D0 NO922028D0 (no) 1992-05-22
NO922028L true NO922028L (no) 1992-11-24

Family

ID=10695460

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922028A NO922028L (no) 1991-05-23 1992-05-22 Azol-derivater

Country Status (16)

Country Link
US (1) US5290776A (no)
EP (1) EP0515107A3 (no)
JP (1) JPH05155887A (no)
KR (1) KR920021547A (no)
AU (1) AU654010B2 (no)
CA (1) CA2069455A1 (no)
CS (1) CS153392A3 (no)
FI (1) FI922340A (no)
GB (2) GB9111130D0 (no)
HU (1) HU210764B (no)
IE (1) IE921655A1 (no)
IL (1) IL101965A0 (no)
NO (1) NO922028L (no)
NZ (1) NZ242865A (no)
TW (1) TW213917B (no)
ZA (1) ZA923767B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356894A (en) * 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
FR2671551B1 (fr) * 1991-01-15 1993-03-12 Adir Nouveaux composes de structure aryl triazinique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO1995003806A1 (fr) * 1993-07-27 1995-02-09 Kyowa Hakko Kogyo Co., Ltd. Remede contre la maladie de parkinson
DE69426620T2 (de) * 1993-09-06 2001-06-21 Kyowa Hakko Kogyo K.K., Tokio/Tokyo Antidepressiva
US5477857A (en) * 1993-09-10 1995-12-26 Discovery Therapeutics, Inc. Diagnostic uses of hydrazinoadenosines
US8003705B2 (en) * 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
WO1999043678A1 (fr) * 1998-02-24 1999-09-02 Kyowa Hakko Kogyo Co., Ltd. Medicaments et prophylaxie contre la maladie de parkinson
AU2707500A (en) * 1998-12-04 2000-06-26 Incept Llc Biocompatible crosslinked polymers
US20030229333A1 (en) * 2002-02-22 2003-12-11 Control Delivery Systems, Inc. Methods for treating otic disorders
FR2842809A1 (fr) * 2002-07-26 2004-01-30 Greenpharma Sas NOUVELLES PYRAZOLO[1,5-a]-1,3,5-TRIAZINES SUBSTITUEES ET LEURS ANALOGUES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION
JPWO2004029056A1 (ja) * 2002-09-24 2006-01-26 協和醗酵工業株式会社 ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジン誘導体
KR100490893B1 (ko) * 2002-10-11 2005-05-23 (주) 비엔씨바이오팜 2-메톡시-1,3,5-트리아진 유도체, 그 제조방법 및 이를 포함하는 항바이러스용 약학적 조성물
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
WO2004092171A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolo[1,5-a]pyrimidines and pyrazolo[1,5-a]pyrimidines useful as a2a adenosin e receptor antagonists
WO2004092177A1 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
WO2004092172A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosin e receptor antagonists
EP1615930A2 (en) 2003-04-09 2006-01-18 Biogen Idec MA, Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagonists
DE602004018637D1 (de) 2003-04-09 2009-02-05 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846423A (en) * 1972-06-08 1974-11-05 Icn Pharmaceuticals Pyrazolo (1,5a) 1,3,5-triazines
BE815405A (en) * 1973-05-22 1974-11-22 Pyrazolo(1,5-a)-s-triazines - and their salts, with bronchospasmolytic activity
US3995039A (en) * 1975-05-27 1976-11-30 Merck & Co., Inc. Pyrazolo [1,5-a] [1,3,5] triazines
GB1579932A (en) * 1976-05-12 1980-11-26 Ici Ltd Herbicidal triazolotriazines
GB2016002B (en) * 1978-01-09 1982-05-06 Aron Sa Amino derivatives of pyrazolo(1,5-a)s triazine
US4565815A (en) * 1982-12-30 1986-01-21 Biomeasure, Inc. Pyrazolo[1,5-a]-1,3,5-triazines
AU2192683A (en) * 1982-12-30 1984-07-05 Biomeasure Incorporated Pyrazolo(1,5-alpha)-1,3,5-triazines
US4560689A (en) * 1983-01-10 1985-12-24 Ciba-Geigy Corporation Heterocyclic-fused pyrazolo-[3,4-d]pyridin-3-ones as benzodiazepine receptor modulators
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
CA1267143A (en) * 1985-06-06 1990-03-27 Sun H. Kim Anti-arthritic 7-phenylpyrazole[1,5-a]-1,3,5- triazine derivatives
DE3677445D1 (de) * 1985-09-30 1991-03-14 Ciba Geigy Ag 2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.
AU612331B2 (en) * 1986-09-30 1991-07-11 Ciba-Geigy Ag 2-substituted-e-fused-(1,2,4)triazolo(1,5-c)pyrimidines pharmaceutical compositions
US4734413A (en) * 1987-03-02 1988-03-29 Riker Laboratories, Inc. Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators
DE8817122U1 (de) * 1988-12-22 1993-02-04 Boehringer Ingelheim Kg, 55218 Ingelheim Neue Xanthinderivate mit Adenosinantogenistischer Wirkung
US4970142A (en) * 1989-02-16 1990-11-13 Konica Corporation Silver halide photographic light-sensitive material containing cyan coupler
GB2244487B (en) * 1990-05-29 1994-02-02 Ici Plc Azole derivatives

Also Published As

Publication number Publication date
NZ242865A (en) 1995-05-26
HU210764B (en) 1995-07-28
CA2069455A1 (en) 1992-11-24
KR920021547A (ko) 1992-12-18
EP0515107A2 (en) 1992-11-25
FI922340A0 (fi) 1992-05-22
IE921655A1 (en) 1992-12-02
TW213917B (no) 1993-10-01
NO922028D0 (no) 1992-05-22
AU654010B2 (en) 1994-10-20
ZA923767B (en) 1993-04-28
CS153392A3 (en) 1992-12-16
JPH05155887A (ja) 1993-06-22
HUT62898A (en) 1993-06-28
IL101965A0 (en) 1992-12-30
US5290776A (en) 1994-03-01
HU9201704D0 (en) 1992-08-28
AU1709392A (en) 1992-11-26
GB9111130D0 (en) 1991-07-17
EP0515107A3 (en) 1993-01-13
FI922340A (fi) 1992-11-24
GB9209622D0 (en) 1992-06-17

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