ATE201870T1 - 3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one - Google Patents

3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one

Info

Publication number
ATE201870T1
ATE201870T1 AT94102762T AT94102762T ATE201870T1 AT E201870 T1 ATE201870 T1 AT E201870T1 AT 94102762 T AT94102762 T AT 94102762T AT 94102762 T AT94102762 T AT 94102762T AT E201870 T1 ATE201870 T1 AT E201870T1
Authority
AT
Austria
Prior art keywords
alkyl
phenyl
beta
substd
spirocyclopropyl
Prior art date
Application number
AT94102762T
Other languages
English (en)
Inventor
Steven L Brickner
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE201870T1 publication Critical patent/ATE201870T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT94102762T 1988-09-15 1989-08-22 3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one ATE201870T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24498888A 1988-09-15 1988-09-15
US25385088A 1988-10-05 1988-10-05
US32494289A 1989-03-17 1989-03-17

Publications (1)

Publication Number Publication Date
ATE201870T1 true ATE201870T1 (de) 2001-06-15

Family

ID=27399816

Family Applications (2)

Application Number Title Priority Date Filing Date
AT89308506T ATE112773T1 (de) 1988-09-15 1989-08-22 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
AT94102762T ATE201870T1 (de) 1988-09-15 1989-08-22 3-(stickstoff substituierte)phenyl-5-beta- amidomethyloxazoliden-2-one

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT89308506T ATE112773T1 (de) 1988-09-15 1989-08-22 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.

Country Status (13)

Country Link
EP (3) EP0359418B1 (de)
JP (2) JP2865211B2 (de)
KR (1) KR0138262B1 (de)
AT (2) ATE112773T1 (de)
AU (1) AU617871B2 (de)
CA (1) CA1335103C (de)
DE (2) DE68929303T2 (de)
DK (2) DK175696B1 (de)
ES (1) ES2157934T3 (de)
GR (1) GR3036491T3 (de)
LV (1) LV12888B (de)
TW (1) TW219936B (de)
WO (1) WO1990002744A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
KR100215627B1 (ko) * 1990-06-07 1999-08-16 레슬리 제인 에드워즈 치료용 헤테로사이클 화합물
DE69230563T2 (de) * 1991-08-14 2000-09-14 Procter & Gamble Pharmaceuticals, Inc. Oxazolidinon-derivate mit antiarrhythmischer und antifibrillatorische wirkung
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
AU666740B2 (en) * 1992-07-08 1996-02-22 Upjohn Company, The 5'-indolinyl oxazolidinones useful against (mycobacterium tuberculosis)
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
DK0788498T3 (da) * 1994-10-26 2001-11-05 Upjohn Co Phenyloxazolidinoner med antimikrobiel virkning
BR9509673A (pt) * 1994-11-15 1997-09-30 Upjohn Co Compostos e uso dos mesmos
CA2208603A1 (en) * 1995-02-03 1996-08-08 The Upjohn Company Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
AU702752B2 (en) * 1995-05-11 1999-03-04 Pharmacia & Upjohn Company Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
US5883093A (en) * 1995-09-12 1999-03-16 Pharmacia & Upjohn Company Phenyloxazolidinone antimicrobials
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19601265A1 (de) 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601264A1 (de) 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
CN1138765C (zh) * 1997-05-30 2004-02-18 法玛西雅厄普约翰美国公司 带有硫代羰基功能基的噁唑烷酮抗菌剂
DE19730847A1 (de) * 1997-07-18 1999-01-28 Bayer Ag Tricyclisch substituierte Oxazolidinone
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
US5998406A (en) * 1997-11-12 1999-12-07 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
WO1999037630A1 (en) * 1998-01-23 1999-07-29 Versicor, Inc. Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
US6441005B1 (en) 1999-07-28 2002-08-27 Pharmacia & Upjohn Company Oxazolidinone compounds and compositions, and methods of using the same
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
WO2002006278A1 (en) 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
AU2001296542B2 (en) 2000-10-02 2007-10-25 Emory University Triptolide analogs for the treatment of autoimmune and inflammatory disorders
PE20020689A1 (es) * 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
BRPI0513083A (pt) * 2004-08-06 2008-04-22 Pharmacia & Upjohn Co Llc oxazolidinonas contendo oxindóis como agentes antibacterianos
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
CA2603943A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc An oxindole oxazolidinone as antibacterial agent
KR101523195B1 (ko) * 2007-12-24 2015-05-27 시플라 리미티드 프로파길화된 아미노인단 유도체의 합성방법
CA2794153C (en) 2010-03-25 2018-01-02 Glaxosmithkline Llc Substituted indoline derivatives as perk inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
EP0609905A1 (de) 1994-08-10
JPH1180139A (ja) 1999-03-26
HK1002234A1 (en) 1998-08-07
EP0359418B1 (de) 1994-10-12
LV12888B (en) 2002-12-20
DK45591D0 (da) 1991-03-13
JP3188418B2 (ja) 2001-07-16
EP0434714A1 (de) 1991-07-03
ES2157934T3 (es) 2001-09-01
KR0138262B1 (ko) 1998-05-15
ATE112773T1 (de) 1994-10-15
DK200401246A (da) 2004-08-18
TW219936B (de) 1994-02-01
DK45591A (da) 1991-03-13
EP0359418A1 (de) 1990-03-21
AU617871B2 (en) 1991-12-05
KR900701780A (ko) 1990-12-04
DK175696B1 (da) 2005-01-24
DE68929303T2 (de) 2002-05-02
DE68918792T2 (de) 1995-03-30
AU4195789A (en) 1990-04-02
DK175940B1 (da) 2005-08-01
WO1990002744A1 (en) 1990-03-22
GR3036491T3 (en) 2001-11-30
DE68918792D1 (de) 1994-11-17
JP2865211B2 (ja) 1999-03-08
EP0609905B1 (de) 2001-06-06
CA1335103C (en) 1995-04-04
DE68929303D1 (de) 2001-07-12
JPH04500665A (ja) 1992-02-06

Similar Documents

Publication Publication Date Title
DE68929303D1 (de) 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
DK160877C (da) Fremgangsmaade til fremstilling af 2-penemforbindelser
DE3879915D1 (de) Heterocyclische verbindungen.
FI931370A0 (fi) Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
DK0791571T3 (da) Benzoylderivater
FR2628104B1 (fr) Para-aminophenols 3-substitues, leur procede de preparation, leur utilisation pour la teinture des fibres keratiniques et les composes intermediaires utilises dans le procede de preparation
DE59105960D1 (de) Oxazolidinone mit ZNS-dämpfender Wirkung.
DK560789D0 (da) Tandpastasammensaetning
GR3003327T3 (en) Substituted 1,8-naphthyridine derivatives and fungicides containing them
MY131690A (en) 6-[triazolyl[3-(trifluoromethyl) phenyl]methyl]-2- quinolinones and -quinolinethiones
ZA81269B (en) 2,3-dihydro-imidazo(1,2-b)pyridazine derivatives,their preparation and their use
EP0319689A3 (en) N-sultam-sulfon amides substituted by a heterocyclic ring, process for their preparation and their use as herbicides and as plant growth regulators
DE58906269D1 (de) Antipsychotisch wirksames Imidazobenzodiazepin.
ATE160806T1 (de) N1-trifluoralkyl substituierte 2-nitro-p- phenylendiaminfarbstoffe
DE59108245D1 (de) Zahnbürste
PT86230A (en) Process for preparing tricyclic ketones substituted with imidazolylmethyl
DE59102829D1 (de) Ergolinderivate.
ES8707960A1 (es) Procedimiento para la obtencion de derivados de triazolo- (3,2-c)perhidroxazin-8-ona
ATE56004T1 (de) Triazinderivat, seine herstellung und verwendung.
ZA873224B (en) 3-amino-dihydropyridines,a process for their preparation,and their use in medicaments
JPS6450809A (en) Photo-polymerizable dental material
ES1008666U (es) Cepillo para limpieza dental con portasedas.
ITPN910035U1 (it) Banco per stiratura per uso domestico

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee