DE68918792D1 - 5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one. - Google Patents
5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one.Info
- Publication number
- DE68918792D1 DE68918792D1 DE68918792T DE68918792T DE68918792D1 DE 68918792 D1 DE68918792 D1 DE 68918792D1 DE 68918792 T DE68918792 T DE 68918792T DE 68918792 T DE68918792 T DE 68918792T DE 68918792 D1 DE68918792 D1 DE 68918792D1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- beta
- phenyl
- amidomethyloxazolidin
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24498888A | 1988-09-15 | 1988-09-15 | |
US25385088A | 1988-10-05 | 1988-10-05 | |
US32494289A | 1989-03-17 | 1989-03-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68918792D1 true DE68918792D1 (de) | 1994-11-17 |
DE68918792T2 DE68918792T2 (de) | 1995-03-30 |
Family
ID=27399816
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68918792T Expired - Fee Related DE68918792T2 (de) | 1988-09-15 | 1989-08-22 | 5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one. |
DE68929303T Expired - Fee Related DE68929303T2 (de) | 1988-09-15 | 1989-08-22 | 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68929303T Expired - Fee Related DE68929303T2 (de) | 1988-09-15 | 1989-08-22 | 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one |
Country Status (14)
Country | Link |
---|---|
EP (3) | EP0609905B1 (de) |
JP (2) | JP2865211B2 (de) |
KR (1) | KR0138262B1 (de) |
AT (2) | ATE112773T1 (de) |
AU (1) | AU617871B2 (de) |
CA (1) | CA1335103C (de) |
DE (2) | DE68918792T2 (de) |
DK (2) | DK175696B1 (de) |
ES (1) | ES2157934T3 (de) |
GR (1) | GR3036491T3 (de) |
HK (1) | HK1002234A1 (de) |
LV (1) | LV12888B (de) |
TW (1) | TW219936B (de) |
WO (1) | WO1990002744A1 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
CA2064815C (en) * | 1990-06-07 | 1999-11-16 | Alan Duncan Robertson | Therapeutic heterocyclic compounds |
CA2115029C (en) * | 1991-08-14 | 2002-03-26 | Stanford Salvatore Pelosi, Jr. | Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents |
SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
EP0648119A1 (de) * | 1992-07-08 | 1995-04-19 | The Upjohn Company | Gegen mycobacterium tuberculosis verwendbare 5'-indolinyloxazolidinone |
US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
DE4425609A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
ATE204277T1 (de) * | 1994-10-26 | 2001-09-15 | Upjohn Co | Phenyloxazolidinone mit antimikrobieller wirkung |
DE69529838T2 (de) * | 1994-11-15 | 2003-11-13 | Upjohn Co | Antibakterielle bizyklische oxazin und thiazin-oxazolidinone |
WO1996023788A1 (en) * | 1995-02-03 | 1996-08-08 | Pharmacia + Upjohn Company | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials |
HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
NZ306310A (en) * | 1995-05-11 | 2001-05-25 | Upjohn Co | Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones |
MX9703040A (es) * | 1995-09-12 | 1997-07-31 | Upjohn Co | Antimicrobianos de feniloxazolidinona. |
ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
DE19601264A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
DE19601265A1 (de) | 1996-01-16 | 1997-07-17 | Bayer Ag | 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone |
DE19601627A1 (de) * | 1996-01-18 | 1997-07-24 | Bayer Ag | Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone |
GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
HRP970049A2 (en) | 1996-02-06 | 1998-04-30 | Bayer Ag | New heteroaryl oxazolidinones |
DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
GB9702213D0 (en) * | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
US6255304B1 (en) | 1997-05-30 | 2001-07-03 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
JP2002501530A (ja) | 1997-05-30 | 2002-01-15 | ファルマシア・アンド・アップジョン・カンパニー | チオカルボニル官能基を有するオキサゾリジノン抗菌剤 |
DE19730847A1 (de) * | 1997-07-18 | 1999-01-28 | Bayer Ag | Tricyclisch substituierte Oxazolidinone |
GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
US5998406A (en) * | 1997-11-12 | 1999-12-07 | Pharmacia & Upjohn Company | Oxazolidinone derivatives and pharmaceutical compositions |
GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
DE19802239A1 (de) * | 1998-01-22 | 1999-07-29 | Bayer Ag | Neue mit Bicyclen substituierte Oxazolidinone |
US6562844B2 (en) | 1998-01-23 | 2003-05-13 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
AU764184B2 (en) * | 1998-01-23 | 2003-08-14 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
US7002020B1 (en) | 1998-01-23 | 2006-02-21 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
CA2372233A1 (en) | 1999-05-27 | 2000-12-07 | Pharmacia & Upjohn Company | Bicyclic oxazolidinones as antibacterial agent |
CN1367780A (zh) * | 1999-07-28 | 2002-09-04 | 法玛西雅厄普约翰美国公司 | 噁唑烷酮类化合物、其制备方法及其应用 |
GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
SK1402003A3 (en) | 2000-07-17 | 2003-08-05 | Ranbaxy Lab Ltd | Oxazolidinone derivatives as antimicrobials |
DE60121986T2 (de) | 2000-10-02 | 2007-07-26 | Emory University | Triptpolidanaloge zur verendung in der behandlung von autoimmunbedingten und entzündlichen erkrankungen |
PE20020689A1 (es) | 2000-11-17 | 2002-08-03 | Upjohn Co | Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno |
US6956040B2 (en) | 2001-07-16 | 2005-10-18 | Ranbaxy Laboratories Limited | Oxazolidinone piperazinyl derivatives as potential antimicrobials |
GB0118407D0 (en) * | 2001-07-27 | 2001-09-19 | Cipla Ltd | Oxazolidinone derivatives as antibacterial agents |
TW200306819A (en) | 2002-01-25 | 2003-12-01 | Vertex Pharma | Indazole compounds useful as protein kinase inhibitors |
US7012088B2 (en) * | 2003-02-24 | 2006-03-14 | Pharmacia & Upjohn Company | Indolone oxazolidinones and derivatives thereof |
US20080262056A1 (en) * | 2004-08-06 | 2008-10-23 | Pfizer Inc | Oxindole Oxazolidinones as Antibacterial Agents |
SE0402763D0 (sv) * | 2004-11-11 | 2004-11-11 | Astrazeneca Ab | Nitro indazole derivatives |
KR20070116989A (ko) * | 2005-04-06 | 2007-12-11 | 파마시아 앤드 업존 캄파니 엘엘씨 | 항균제로서의 옥신돌 옥사졸리디논 |
AU2006231919A1 (en) | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
US8461388B2 (en) * | 2007-12-24 | 2013-06-11 | Cipla Limited | Process for the synthesis of propargylated aminoindan derivatives |
CA2794153C (en) | 2010-03-25 | 2018-01-02 | Glaxosmithkline Llc | Substituted indoline derivatives as perk inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8506659A1 (es) * | 1983-06-07 | 1985-08-01 | Du Pont | Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno. |
CA1260948A (en) * | 1984-12-05 | 1989-09-26 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents |
US4801600A (en) * | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
-
1989
- 1989-08-22 DE DE68918792T patent/DE68918792T2/de not_active Expired - Fee Related
- 1989-08-22 AU AU41957/89A patent/AU617871B2/en not_active Ceased
- 1989-08-22 AT AT89308506T patent/ATE112773T1/de not_active IP Right Cessation
- 1989-08-22 WO PCT/US1989/003548 patent/WO1990002744A1/en not_active Application Discontinuation
- 1989-08-22 DE DE68929303T patent/DE68929303T2/de not_active Expired - Fee Related
- 1989-08-22 AT AT94102762T patent/ATE201870T1/de not_active IP Right Cessation
- 1989-08-22 EP EP94102762A patent/EP0609905B1/de not_active Expired - Lifetime
- 1989-08-22 EP EP89308506A patent/EP0359418B1/de not_active Expired - Lifetime
- 1989-08-22 EP EP89909990A patent/EP0434714A1/de active Pending
- 1989-08-22 JP JP1509255A patent/JP2865211B2/ja not_active Expired - Fee Related
- 1989-08-22 ES ES94102762T patent/ES2157934T3/es not_active Expired - Lifetime
- 1989-08-28 CA CA000609594A patent/CA1335103C/en not_active Expired - Fee Related
- 1989-08-29 TW TW078106662A patent/TW219936B/zh active
-
1990
- 1990-05-15 KR KR1019900701012A patent/KR0138262B1/ko not_active IP Right Cessation
-
1991
- 1991-03-13 DK DK199100455A patent/DK175696B1/da not_active IP Right Cessation
-
1998
- 1998-02-18 HK HK98101252A patent/HK1002234A1/xx not_active IP Right Cessation
- 1998-07-07 JP JP19194998A patent/JP3188418B2/ja not_active Expired - Fee Related
-
2001
- 2001-08-31 GR GR20010401350T patent/GR3036491T3/el not_active IP Right Cessation
-
2002
- 2002-06-06 LV LVP-02-104A patent/LV12888B/en unknown
-
2004
- 2004-08-18 DK DK200401246A patent/DK175940B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU4195789A (en) | 1990-04-02 |
EP0359418A1 (de) | 1990-03-21 |
DK175696B1 (da) | 2005-01-24 |
DE68929303T2 (de) | 2002-05-02 |
CA1335103C (en) | 1995-04-04 |
ATE112773T1 (de) | 1994-10-15 |
EP0609905A1 (de) | 1994-08-10 |
TW219936B (de) | 1994-02-01 |
JPH04500665A (ja) | 1992-02-06 |
JPH1180139A (ja) | 1999-03-26 |
JP3188418B2 (ja) | 2001-07-16 |
ATE201870T1 (de) | 2001-06-15 |
DK45591D0 (da) | 1991-03-13 |
EP0359418B1 (de) | 1994-10-12 |
GR3036491T3 (en) | 2001-11-30 |
JP2865211B2 (ja) | 1999-03-08 |
EP0609905B1 (de) | 2001-06-06 |
DE68929303D1 (de) | 2001-07-12 |
EP0434714A1 (de) | 1991-07-03 |
DK175940B1 (da) | 2005-08-01 |
LV12888B (en) | 2002-12-20 |
KR900701780A (ko) | 1990-12-04 |
KR0138262B1 (ko) | 1998-05-15 |
DK200401246A (da) | 2004-08-18 |
AU617871B2 (en) | 1991-12-05 |
HK1002234A1 (en) | 1998-08-07 |
WO1990002744A1 (en) | 1990-03-22 |
DK45591A (da) | 1991-03-13 |
DE68918792T2 (de) | 1995-03-30 |
ES2157934T3 (es) | 2001-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US |
|
8339 | Ceased/non-payment of the annual fee |