DK45591D0 - 5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner - Google Patents

5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner

Info

Publication number
DK45591D0
DK45591D0 DK91455A DK45591A DK45591D0 DK 45591 D0 DK45591 D0 DK 45591D0 DK 91455 A DK91455 A DK 91455A DK 45591 A DK45591 A DK 45591A DK 45591 D0 DK45591 D0 DK 45591D0
Authority
DK
Denmark
Prior art keywords
alkyl
5beta
phenyl
substd
onhylided
Prior art date
Application number
DK91455A
Other languages
English (en)
Other versions
DK45591A (da
DK175696B1 (da
Inventor
Steven J Brickner
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK45591D0 publication Critical patent/DK45591D0/da
Publication of DK45591A publication Critical patent/DK45591A/da
Priority to DK200401246A priority Critical patent/DK175940B1/da
Application granted granted Critical
Publication of DK175696B1 publication Critical patent/DK175696B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK199100455A 1988-09-15 1991-03-13 5'-Indolinyloxazolidin-2-oner med farmaceutisk acceptable salte deraf DK175696B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US24498888A 1988-09-15 1988-09-15
US24498888 1988-09-15
US25385088A 1988-10-05 1988-10-05
US25385088 1988-10-05
US32494289A 1989-03-17 1989-03-17
US32494289 1989-03-17
US8903548 1989-08-22
PCT/US1989/003548 WO1990002744A1 (en) 1988-09-15 1989-08-22 In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones

Publications (3)

Publication Number Publication Date
DK45591D0 true DK45591D0 (da) 1991-03-13
DK45591A DK45591A (da) 1991-03-13
DK175696B1 DK175696B1 (da) 2005-01-24

Family

ID=27399816

Family Applications (2)

Application Number Title Priority Date Filing Date
DK199100455A DK175696B1 (da) 1988-09-15 1991-03-13 5'-Indolinyloxazolidin-2-oner med farmaceutisk acceptable salte deraf
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Country Status (14)

Country Link
EP (3) EP0359418B1 (da)
JP (2) JP2865211B2 (da)
KR (1) KR0138262B1 (da)
AT (2) ATE112773T1 (da)
AU (1) AU617871B2 (da)
CA (1) CA1335103C (da)
DE (2) DE68918792T2 (da)
DK (2) DK175696B1 (da)
ES (1) ES2157934T3 (da)
GR (1) GR3036491T3 (da)
HK (1) HK1002234A1 (da)
LV (1) LV12888B (da)
TW (1) TW219936B (da)
WO (1) WO1990002744A1 (da)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
CZ283323B6 (cs) * 1991-08-14 1998-02-18 Procter And Gamble Pharmaceuticals, Inc. Cyklické urethany použitelné jako antiarytmická a antifibrilační činidla a farmaceutické přípravky, které je obsahují
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
KR950702417A (ko) * 1992-07-08 1995-07-29 로렌스 티. 웰츠 마이코박테륨 투베르쿨로시스에 대해 유용한 5′-인돌리닐 옥사졸리디논(5′-indolinyl oxazolidinones useful against mycobacterium tuberculosis)
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
BR9509136A (pt) * 1994-10-26 1998-07-21 Upjohn Co Composto e uso do mesmo
MX9703543A (es) * 1994-11-15 1997-08-30 Upjohn Co Antibacterianos de oxazina biciclica y oxazolidinona tiazina.
DE69615002T2 (de) * 1995-02-03 2002-06-13 Pharmacia & Upjohn Co., Kalamazoo Durch hetero-aromatische ring substituierte phenyloxazolidinone als antimikrobielles mittel
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
MX9708627A (es) * 1995-05-11 1998-02-28 Upjohn Co Oxazolidinonas de diazinilo y carbazinilo espirociclicas y biciclicas.
US5883093A (en) * 1995-09-12 1999-03-16 Pharmacia & Upjohn Company Phenyloxazolidinone antimicrobials
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19601264A1 (de) 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601265A1 (de) 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
JP2002501530A (ja) 1997-05-30 2002-01-15 ファルマシア・アンド・アップジョン・カンパニー チオカルボニル官能基を有するオキサゾリジノン抗菌剤
DE19730847A1 (de) * 1997-07-18 1999-01-28 Bayer Ag Tricyclisch substituierte Oxazolidinone
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
DK1030852T3 (da) * 1997-11-12 2003-12-22 Upjohn Co Oxazolidinonderivater og farmaceutiske præparater
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
BR9907183A (pt) 1998-01-23 2003-06-10 Versicor Inc Colet neas combinatórias de oxazolidinona, composições e processos de preparação
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU767380B2 (en) * 1999-05-27 2003-11-06 Pharmacia & Upjohn Company Bicyclic oxazolidinones as antibacterial agent
NZ516853A (en) 1999-07-28 2003-11-28 Upjohn Co Oxazolidinones and their use as anti-infectives
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6734307B2 (en) 2000-07-17 2004-05-11 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
ATE469907T1 (de) 2000-10-02 2010-06-15 Univ Emory Triptolid-analoga zur behandlung von autoimmunkranheiten und entzündungen
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20080262056A1 (en) * 2004-08-06 2008-10-23 Pfizer Inc Oxindole Oxazolidinones as Antibacterial Agents
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
EP1869029A1 (en) * 2005-04-06 2007-12-26 Pharmacia & Upjohn Company LLC An oxindole oxazolidinone as antibacterial agent
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
CA2708820C (en) * 2007-12-24 2016-05-10 Cipla Limited Process for the synthesis of propargylated aminoindan derivatives
BR112012024380A2 (pt) 2010-03-25 2015-09-15 Glaxosmithkline Llc compostos químicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
AU4195789A (en) 1990-04-02
DK45591A (da) 1991-03-13
JP2865211B2 (ja) 1999-03-08
AU617871B2 (en) 1991-12-05
WO1990002744A1 (en) 1990-03-22
JPH1180139A (ja) 1999-03-26
GR3036491T3 (en) 2001-11-30
DE68918792T2 (de) 1995-03-30
LV12888B (en) 2002-12-20
KR0138262B1 (ko) 1998-05-15
EP0609905A1 (en) 1994-08-10
ATE201870T1 (de) 2001-06-15
CA1335103C (en) 1995-04-04
ES2157934T3 (es) 2001-09-01
EP0609905B1 (en) 2001-06-06
JP3188418B2 (ja) 2001-07-16
JPH04500665A (ja) 1992-02-06
ATE112773T1 (de) 1994-10-15
DK175696B1 (da) 2005-01-24
DE68929303D1 (de) 2001-07-12
HK1002234A1 (en) 1998-08-07
EP0434714A1 (en) 1991-07-03
DE68929303T2 (de) 2002-05-02
DE68918792D1 (de) 1994-11-17
DK175940B1 (da) 2005-08-01
EP0359418A1 (en) 1990-03-21
EP0359418B1 (en) 1994-10-12
TW219936B (da) 1994-02-01
DK200401246A (da) 2004-08-18
KR900701780A (ko) 1990-12-04

Similar Documents

Publication Publication Date Title
DK45591D0 (da) 5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner
SE8603966D0 (sv) Fluoroaluminosilicate glass powder for dental glass ionomer cement
DK0791571T3 (da) Benzoylderivater
HUT51863A (da)
FI931370A (fi) Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
IE892795L (en) Ó,Ó-Disubstituted N-cycloalkylalkylbenzylamines, process for¹their preparation, their use as a medicament and their¹synthesis intermediates
GR3003327T3 (en) Substituted 1,8-naphthyridine derivatives and fungicides containing them
JPS6440449A (en) Substituted 2-nitromethaphenylenediamine, manufacture and hair dye composition
DE69015471D1 (de) 1-Benzhydrylazetidine, deren Herstellung und Verwendung als Zwischenprodukte zur Herstellung von Verbindungen mit antimikrobieller Wirkung.
PT79969B (de) Isoxazol-derivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS5583758A (en) Novel 3*44diazaabicyclo*4*1*0*heptenee*2**onee *5**its manufacture and medicine containing it
ES2095933T3 (es) Cepillo de dientes.
DE69223362D1 (de) N1-Trifluoralkyl substituierte 2-Nitro-p-Phenylendiaminfarbstoffe
ES475977A1 (es) Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas
DE68922596D1 (de) 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen.
Palani Professor Dr. N. Subbu Reddiar's contributions for the enrichment of Tamil
ATE66145T1 (de) Pharmazeutische verwendung aromatischer thioaether.
DE59102829D1 (de) Ergolinderivate.
EP0244713A3 (en) 3-amino-dihydropyridines, process for their preparation and their use as medicaments
DK293889D0 (da) 2-amino-7-hydroxytetralinethere
JPS6450809A (en) Photo-polymerizable dental material
RU1836941C (ru) Шина дл кисти
ES1008666U (es) Cepillo para limpieza dental con portasedas.
DK4579A (da) Tandboerste
ITPN910035U1 (it) Banco per stiratura per uso domestico

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK