DE68922596D1 - 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen. - Google Patents

3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen.

Info

Publication number
DE68922596D1
DE68922596D1 DE68922596T DE68922596T DE68922596D1 DE 68922596 D1 DE68922596 D1 DE 68922596D1 DE 68922596 T DE68922596 T DE 68922596T DE 68922596 T DE68922596 T DE 68922596T DE 68922596 D1 DE68922596 D1 DE 68922596D1
Authority
DE
Germany
Prior art keywords
azabicycloheptane
oxadiazol
ethyl
preparation
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68922596T
Other languages
English (en)
Other versions
DE68922596T2 (de
Inventor
Michael Stewart Beecham Hadley
Paul Adrian Beecham Phar Wyman
Barry Sidney Beecham Pha Orlek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE68922596D1 publication Critical patent/DE68922596D1/de
Publication of DE68922596T2 publication Critical patent/DE68922596T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE68922596T 1988-12-23 1989-12-21 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen. Expired - Fee Related DE68922596T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888830226A GB8830226D0 (en) 1988-12-23 1988-12-23 Novel compounds

Publications (2)

Publication Number Publication Date
DE68922596D1 true DE68922596D1 (de) 1995-06-14
DE68922596T2 DE68922596T2 (de) 1995-09-28

Family

ID=10649157

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922596T Expired - Fee Related DE68922596T2 (de) 1988-12-23 1989-12-21 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen.

Country Status (13)

Country Link
US (1) US5043342A (de)
EP (1) EP0375450B1 (de)
JP (1) JPH02215782A (de)
KR (1) KR900009638A (de)
AT (1) ATE122352T1 (de)
AU (1) AU620957B2 (de)
CA (1) CA2006436A1 (de)
DE (1) DE68922596T2 (de)
DK (1) DK656889A (de)
GB (1) GB8830226D0 (de)
NZ (1) NZ231970A (de)
PT (1) PT92668B (de)
ZA (1) ZA899821B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
KR100441404B1 (ko) * 2002-01-24 2004-07-23 한국과학기술연구원 신규한 알케닐 아자 두 고리 화합물 및 그 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
GB1053085A (de) * 1964-03-26
US3501471A (en) * 1966-09-21 1970-03-17 American Cyanamid Co Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
JPS6191185A (ja) * 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
US4599344A (en) * 1984-10-31 1986-07-08 Schering A.G. Quinuclidines and quinuclidinium salts as antiarrhythmic agents
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
EP0261763B1 (de) * 1986-06-27 1994-02-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
ES2053748T3 (es) * 1987-09-10 1994-08-01 Merck Sharp & Dohme Oxazoles y tiazoles para el tratamiento de la demencia senil.
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB8830226D0 (en) 1989-02-22
ATE122352T1 (de) 1995-05-15
DE68922596T2 (de) 1995-09-28
CA2006436A1 (en) 1990-06-23
EP0375450A3 (de) 1991-07-31
DK656889D0 (da) 1989-12-21
AU620957B2 (en) 1992-02-27
PT92668A (pt) 1990-06-29
DK656889A (da) 1990-06-24
JPH02215782A (ja) 1990-08-28
US5043342A (en) 1991-08-27
PT92668B (pt) 1995-09-12
ZA899821B (en) 1990-12-28
EP0375450B1 (de) 1995-05-10
EP0375450A2 (de) 1990-06-27
KR900009638A (ko) 1990-07-05
NZ231970A (en) 1992-01-29
AU4706489A (en) 1990-06-28

Similar Documents

Publication Publication Date Title
DE69030206T2 (de) Pyrazolopyridinverbindungen und Verfahren zu ihrer Herstellung
NO921835L (no) Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav
CA2076589A1 (en) Naphthylethylureas and naphthylethylthioureas, the process for their preparation and pharmaceutical compositions holding same
NO902800D0 (no) Fremgangsmaate for fremstilling av 11beta-aryl-4-oestrener.
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
NO873125D0 (no) Fremgangsmaate for fremstilling av antibakterielle forbindelser.
DE68922596D1 (de) 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen.
NO903291D0 (no) Renin-hemmende aminooligohydroksy-derivater.
GR3000512T3 (en) Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds
HUT54682A (en) Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
IL85231A0 (en) Substituted 3-phenyl-7h-thiazolo(3,2-b)(1,2,4)triazin-7-ones,a process for the preparation thereof,pharmaceutical compositions containing same and the use thereof
ATE90942T1 (de) (3-diethylaminopropyl)-1-amino-5methyldipyrido(4,3-b>(3,4-f>indoltrihydrochlori .

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee