ZA899821B - Novel compounds - Google Patents

Novel compounds

Info

Publication number
ZA899821B
ZA899821B ZA899821A ZA899821A ZA899821B ZA 899821 B ZA899821 B ZA 899821B ZA 899821 A ZA899821 A ZA 899821A ZA 899821 A ZA899821 A ZA 899821A ZA 899821 B ZA899821 B ZA 899821B
Authority
ZA
South Africa
Prior art keywords
novel compounds
dementia
prophylaxis
chem
compound
Prior art date
Application number
ZA899821A
Other languages
English (en)
Inventor
Michael Stewart Hadley
Stewart Hadley Michael
Paul Adrian Wyman
Adrian Wyman Paul
Barry Sidney Orleck
Sidney Orleck Barry
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA899821B publication Critical patent/ZA899821B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
ZA899821A 1988-12-23 1989-12-21 Novel compounds ZA899821B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888830226A GB8830226D0 (en) 1988-12-23 1988-12-23 Novel compounds

Publications (1)

Publication Number Publication Date
ZA899821B true ZA899821B (en) 1990-12-28

Family

ID=10649157

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA899821A ZA899821B (en) 1988-12-23 1989-12-21 Novel compounds

Country Status (13)

Country Link
US (1) US5043342A (xx)
EP (1) EP0375450B1 (xx)
JP (1) JPH02215782A (xx)
KR (1) KR900009638A (xx)
AT (1) ATE122352T1 (xx)
AU (1) AU620957B2 (xx)
CA (1) CA2006436A1 (xx)
DE (1) DE68922596T2 (xx)
DK (1) DK656889A (xx)
GB (1) GB8830226D0 (xx)
NZ (1) NZ231970A (xx)
PT (1) PT92668B (xx)
ZA (1) ZA899821B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69026197T2 (de) * 1989-10-07 1997-01-09 Beecham Group Plc Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
KR100441404B1 (ko) * 2002-01-24 2004-07-23 한국과학기술연구원 신규한 알케닐 아자 두 고리 화합물 및 그 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
GB1053085A (xx) * 1964-03-26
US3501471A (en) * 1966-09-21 1970-03-17 American Cyanamid Co Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
JPS6191185A (ja) * 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−1,4−ジヒドロピリジン誘導体
US4599344A (en) * 1984-10-31 1986-07-08 Schering A.G. Quinuclidines and quinuclidinium salts as antiarrhythmic agents
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
EP0307141B1 (en) * 1987-09-10 1993-01-13 MERCK SHARP & DOHME LTD. Oxazoles and thiazoles for the treatment of senile dementia
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE68922596D1 (de) 1995-06-14
AU4706489A (en) 1990-06-28
PT92668A (pt) 1990-06-29
DE68922596T2 (de) 1995-09-28
ATE122352T1 (de) 1995-05-15
EP0375450B1 (en) 1995-05-10
DK656889A (da) 1990-06-24
CA2006436A1 (en) 1990-06-23
NZ231970A (en) 1992-01-29
GB8830226D0 (en) 1989-02-22
EP0375450A2 (en) 1990-06-27
KR900009638A (ko) 1990-07-05
PT92668B (pt) 1995-09-12
EP0375450A3 (en) 1991-07-31
JPH02215782A (ja) 1990-08-28
DK656889D0 (da) 1989-12-21
AU620957B2 (en) 1992-02-27
US5043342A (en) 1991-08-27

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