ATE136031T1 - Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen - Google Patents

Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Info

Publication number
ATE136031T1
ATE136031T1 AT90310632T AT90310632T ATE136031T1 AT E136031 T1 ATE136031 T1 AT E136031T1 AT 90310632 T AT90310632 T AT 90310632T AT 90310632 T AT90310632 T AT 90310632T AT E136031 T1 ATE136031 T1 AT E136031T1
Authority
AT
Austria
Prior art keywords
hydrogen
processes
production
pharmaceutical preparations
intermediate products
Prior art date
Application number
AT90310632T
Other languages
English (en)
Inventor
Sarah Margaret Smithkl Jenkins
Pinnacles The
Harry John Smithklin Wadsworth
Pinnacles
Sidney Barry Smithkline Orlek
Steven Mark Smithklin Bromidge
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898922620A external-priority patent/GB8922620D0/en
Priority claimed from GB909016069A external-priority patent/GB9016069D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of ATE136031T1 publication Critical patent/ATE136031T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
AT90310632T 1989-10-07 1990-09-28 Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen ATE136031T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898922620A GB8922620D0 (en) 1989-10-07 1989-10-07 Novel compounds
GB909016069A GB9016069D0 (en) 1990-07-21 1990-07-21 Novel compounds

Publications (1)

Publication Number Publication Date
ATE136031T1 true ATE136031T1 (de) 1996-04-15

Family

ID=26296014

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90310632T ATE136031T1 (de) 1989-10-07 1990-09-28 Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Country Status (10)

Country Link
US (1) US5981545A (de)
EP (1) EP0427390B1 (de)
JP (1) JPH03145491A (de)
KR (1) KR910007929A (de)
AT (1) ATE136031T1 (de)
AU (1) AU639493B2 (de)
CA (1) CA2027093A1 (de)
DE (1) DE69026197T2 (de)
IE (1) IE903576A1 (de)
PT (1) PT95520A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
SE9201478D0 (sv) * 1992-05-11 1992-05-11 Kabi Pharmacia Ab Heteroaromatic quinuclidinenes, their use and preparation
US5393767A (en) * 1993-08-26 1995-02-28 Dowelanco Insect control with substituted triazole and tetrazole compounds
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
FR2862647B1 (fr) * 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
CA2620333A1 (en) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
WO2008030651A1 (en) * 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US8987315B2 (en) 2009-12-31 2015-03-24 Innocrin Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US20130225583A1 (en) * 2010-10-21 2013-08-29 Gerald W. Shipps, Jr. Substituted amino-triazolyl pde10 inhibitors

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813384A (en) * 1972-01-17 1974-05-28 Asta Werke Ag Chem Fab Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof
FR2414044A1 (fr) * 1978-01-10 1979-08-03 Pharmindustrie Nouveaux derives d'aza-1 bicyclo(2,2,2) octane, utilisables comme medicaments
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
EP0261763B1 (de) * 1986-06-27 1994-02-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen
ATE133415T1 (de) * 1987-04-15 1996-02-15 Beecham Group Plc Am brückenkopf substituierte azabicyclenderivate
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
DE3877470T2 (de) * 1987-09-10 1993-06-24 Merck Sharp & Dohme Oxazole und thiazole zur behandlung seniler demenz.
NZ226000A (en) * 1987-09-10 1991-06-25 Merck Sharp & Dohme Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (de) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclische-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
GB8808926D0 (en) * 1988-04-15 1988-05-18 Beecham Group Plc Novel compounds
EP0363085A3 (de) * 1988-10-03 1991-03-27 Beecham Group Plc Chemische Verbindungen
CA2000041A1 (en) * 1988-10-13 1990-04-13 Barry S. Orlek Compounds
GB8830226D0 (en) * 1988-12-23 1989-02-22 Beecham Group Plc Novel compounds
EP0402056A3 (de) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors

Also Published As

Publication number Publication date
EP0427390B1 (de) 1996-03-27
DE69026197T2 (de) 1997-01-09
PT95520A (pt) 1991-08-14
DE69026197D1 (de) 1996-05-02
JPH03145491A (ja) 1991-06-20
CA2027093A1 (en) 1991-04-08
KR910007929A (ko) 1991-05-30
EP0427390A3 (en) 1992-02-12
IE903576A1 (en) 1991-04-10
AU6382390A (en) 1991-04-11
EP0427390A2 (de) 1991-05-15
US5981545A (en) 1999-11-09
AU639493B2 (en) 1993-07-29

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties