DE69026197D1 - Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents
Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische ZubereitungenInfo
- Publication number
- DE69026197D1 DE69026197D1 DE69026197T DE69026197T DE69026197D1 DE 69026197 D1 DE69026197 D1 DE 69026197D1 DE 69026197 T DE69026197 T DE 69026197T DE 69026197 T DE69026197 T DE 69026197T DE 69026197 D1 DE69026197 D1 DE 69026197D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- intermediates
- processes
- preparation
- pharmaceutical preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898922620A GB8922620D0 (en) | 1989-10-07 | 1989-10-07 | Novel compounds |
GB909016069A GB9016069D0 (en) | 1990-07-21 | 1990-07-21 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69026197D1 true DE69026197D1 (de) | 1996-05-02 |
DE69026197T2 DE69026197T2 (de) | 1997-01-09 |
Family
ID=26296014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69026197T Expired - Fee Related DE69026197T2 (de) | 1989-10-07 | 1990-09-28 | Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Country Status (10)
Country | Link |
---|---|
US (1) | US5981545A (de) |
EP (1) | EP0427390B1 (de) |
JP (1) | JPH03145491A (de) |
KR (1) | KR910007929A (de) |
AT (1) | ATE136031T1 (de) |
AU (1) | AU639493B2 (de) |
CA (1) | CA2027093A1 (de) |
DE (1) | DE69026197T2 (de) |
IE (1) | IE903576A1 (de) |
PT (1) | PT95520A (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE922270A1 (en) * | 1991-07-26 | 1993-01-27 | Akzo Nv | Pyrazole derivatives |
SE9201478D0 (sv) * | 1992-05-11 | 1992-05-11 | Kabi Pharmacia Ab | Heteroaromatic quinuclidinenes, their use and preparation |
US5393767A (en) * | 1993-08-26 | 1995-02-28 | Dowelanco | Insect control with substituted triazole and tetrazole compounds |
US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
FR2862647B1 (fr) * | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
JP2009506069A (ja) * | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258359A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin |
AU2007292848A1 (en) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
AU2010339508B2 (en) * | 2009-12-31 | 2016-02-04 | Innocrin Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
US20130225583A1 (en) * | 2010-10-21 | 2013-08-29 | Gerald W. Shipps, Jr. | Substituted amino-triazolyl pde10 inhibitors |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3813384A (en) * | 1972-01-17 | 1974-05-28 | Asta Werke Ag Chem Fab | Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof |
FR2414044A1 (fr) * | 1978-01-10 | 1979-08-03 | Pharmindustrie | Nouveaux derives d'aza-1 bicyclo(2,2,2) octane, utilisables comme medicaments |
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
EP0261763B1 (de) * | 1986-06-27 | 1994-02-09 | Beecham Group Plc | Verbrückte bicyclische N-heterocyclische Verbindungen |
ATE133415T1 (de) * | 1987-04-15 | 1996-02-15 | Beecham Group Plc | Am brückenkopf substituierte azabicyclenderivate |
GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
GB8717446D0 (en) * | 1987-07-23 | 1987-08-26 | Merck Sharp & Dohme | Chemical compounds |
EP0307141B1 (de) * | 1987-09-10 | 1993-01-13 | MERCK SHARP & DOHME LTD. | Oxazole und Thiazole zur Behandlung seniler Demenz |
NZ226000A (en) * | 1987-09-10 | 1991-06-25 | Merck Sharp & Dohme | Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions |
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
EP0322182A3 (de) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Azabicyclische-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
IL88846A0 (en) * | 1988-01-08 | 1989-07-31 | Merck Sharp & Dohme | Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them |
GB8808926D0 (en) * | 1988-04-15 | 1988-05-18 | Beecham Group Plc | Novel compounds |
EP0363085A3 (de) * | 1988-10-03 | 1991-03-27 | Beecham Group Plc | Chemische Verbindungen |
CA2000041A1 (en) * | 1988-10-13 | 1990-04-13 | Barry S. Orlek | Compounds |
GB8830226D0 (en) * | 1988-12-23 | 1989-02-22 | Beecham Group Plc | Novel compounds |
EP0402056A3 (de) * | 1989-06-06 | 1991-09-04 | Beecham Group p.l.c. | Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
US5200419A (en) * | 1990-05-21 | 1993-04-06 | Warner-Lambert Company | Substituted tetrazoles and derivatives thereof acting at muscarinic receptors |
-
1990
- 1990-09-28 EP EP90310632A patent/EP0427390B1/de not_active Expired - Lifetime
- 1990-09-28 AT AT90310632T patent/ATE136031T1/de not_active IP Right Cessation
- 1990-09-28 DE DE69026197T patent/DE69026197T2/de not_active Expired - Fee Related
- 1990-10-04 US US07/594,034 patent/US5981545A/en not_active Expired - Fee Related
- 1990-10-04 PT PT95520A patent/PT95520A/pt not_active Application Discontinuation
- 1990-10-05 CA CA002027093A patent/CA2027093A1/en not_active Abandoned
- 1990-10-05 IE IE357690A patent/IE903576A1/en unknown
- 1990-10-05 AU AU63823/90A patent/AU639493B2/en not_active Ceased
- 1990-10-06 KR KR1019900015906A patent/KR910007929A/ko not_active Application Discontinuation
- 1990-10-08 JP JP2268562A patent/JPH03145491A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT95520A (pt) | 1991-08-14 |
EP0427390A3 (en) | 1992-02-12 |
AU639493B2 (en) | 1993-07-29 |
IE903576A1 (en) | 1991-04-10 |
AU6382390A (en) | 1991-04-11 |
DE69026197T2 (de) | 1997-01-09 |
ATE136031T1 (de) | 1996-04-15 |
KR910007929A (ko) | 1991-05-30 |
EP0427390B1 (de) | 1996-03-27 |
US5981545A (en) | 1999-11-09 |
EP0427390A2 (de) | 1991-05-15 |
JPH03145491A (ja) | 1991-06-20 |
CA2027093A1 (en) | 1991-04-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |