EA200701895A1 - Оксиндол-оксазолидинон в качестве антибактериального агента - Google Patents

Оксиндол-оксазолидинон в качестве антибактериального агента

Info

Publication number
EA200701895A1
EA200701895A1 EA200701895A EA200701895A EA200701895A1 EA 200701895 A1 EA200701895 A1 EA 200701895A1 EA 200701895 A EA200701895 A EA 200701895A EA 200701895 A EA200701895 A EA 200701895A EA 200701895 A1 EA200701895 A1 EA 200701895A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibacterial agent
oxasolidinon
oxindol
compound
cyclopropylmethyl
Prior art date
Application number
EA200701895A
Other languages
English (en)
Inventor
Михаил Федор Гордеев
Вара Прасад Венката Нагендра Джозиюла
Гари Уэйн Льюэр
Original Assignee
ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи filed Critical ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи
Publication of EA200701895A1 publication Critical patent/EA200701895A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Согласно настоящему изобретению предложено соединение формулы Iили его фармацевтически приемлемая соль, где Rпредставляет собой Салкил, возможно замещенный атомом фтора, или Rпредставляет собой циклопропил или циклопропилметил; и Rпредставляет собой метил или этил. Это соединение полезно в качестве антибактериального агента.
EA200701895A 2005-04-06 2006-03-27 Оксиндол-оксазолидинон в качестве антибактериального агента EA200701895A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66871605P 2005-04-06 2005-04-06
US68400005P 2005-05-24 2005-05-24
PCT/IB2006/000952 WO2006106426A1 (en) 2005-04-06 2006-03-27 An oxindole oxazolidinone as antibacterial agent

Publications (1)

Publication Number Publication Date
EA200701895A1 true EA200701895A1 (ru) 2008-04-28

Family

ID=36648715

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701895A EA200701895A1 (ru) 2005-04-06 2006-03-27 Оксиндол-оксазолидинон в качестве антибактериального агента

Country Status (21)

Country Link
US (1) US20060229348A1 (ru)
EP (1) EP1869029A1 (ru)
KR (1) KR20070116989A (ru)
AP (1) AP2007004173A0 (ru)
AR (1) AR053350A1 (ru)
AU (1) AU2006231918A1 (ru)
BR (1) BRPI0607873A2 (ru)
CA (1) CA2603943A1 (ru)
CR (1) CR9418A (ru)
DO (1) DOP2006000079A (ru)
EA (1) EA200701895A1 (ru)
GT (1) GT200600132A (ru)
IL (1) IL186051A0 (ru)
MX (1) MX2007011873A (ru)
NL (1) NL1031524C2 (ru)
NO (1) NO20075547L (ru)
PE (1) PE20061356A1 (ru)
TN (1) TNSN07374A1 (ru)
TW (1) TW200637855A (ru)
UY (1) UY29453A1 (ru)
WO (1) WO2006106426A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102214988B1 (ko) * 2019-06-20 2021-02-10 영남대학교 산학협력단 신규한 옥시인돌 유도체 및 이를 유효성분으로 함유하는 항균용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
ATE112773T1 (de) * 1988-09-15 1994-10-15 Upjohn Co 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DE19649095A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue Heteroaryl-Oxazolidinone
JP2002511445A (ja) * 1998-04-14 2002-04-16 サムスン ファイン ケミカルズ カンパニー リミテッド キラル（ｓ）−２，３−二置換−１−プロピルアミン誘導体の製造方法
CN1142162C (zh) * 1999-05-27 2004-03-17 法玛西雅厄普约翰美国公司 作为抗菌剂的新的双环噁唑烷酮
PE20011124A1 (es) * 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
CA2575702A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxindole oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
CR9418A (es) 2007-10-21
US20060229348A1 (en) 2006-10-12
PE20061356A1 (es) 2007-01-13
AU2006231918A1 (en) 2006-10-12
UY29453A1 (es) 2006-11-30
NL1031524C2 (nl) 2007-01-30
KR20070116989A (ko) 2007-12-11
DOP2006000079A (es) 2006-11-15
AR053350A1 (es) 2007-05-02
EP1869029A1 (en) 2007-12-26
CA2603943A1 (en) 2006-10-12
BRPI0607873A2 (pt) 2009-10-20
IL186051A0 (en) 2008-02-09
WO2006106426A1 (en) 2006-10-12
GT200600132A (es) 2006-11-22
AP2007004173A0 (en) 2007-10-31
NO20075547L (no) 2007-11-01
TNSN07374A1 (fr) 2009-03-17
NL1031524A1 (nl) 2006-10-09
MX2007011873A (es) 2007-11-07
TW200637855A (en) 2006-11-01

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