MX2007012386A - 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacterianos. - Google Patents

7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacterianos.

Info

Publication number
MX2007012386A
MX2007012386A MX2007012386A MX2007012386A MX2007012386A MX 2007012386 A MX2007012386 A MX 2007012386A MX 2007012386 A MX2007012386 A MX 2007012386A MX 2007012386 A MX2007012386 A MX 2007012386A MX 2007012386 A MX2007012386 A MX 2007012386A
Authority
MX
Mexico
Prior art keywords
sup
antibacterial agents
fluoro
oxazolidinones
indol
Prior art date
Application number
MX2007012386A
Other languages
English (en)
Inventor
Mikhail Fedor Gordeev
Vara Prasad Venkata Nagendra Josyula
Gary Wayne Luehr
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of MX2007012386A publication Critical patent/MX2007012386A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion proporciona un compuesto de formula I (ver formula I) o una sal farmaceuticamente aceptable del mismo en la que R1 es alquilo C1-4, opcionalmente sustituido con un atomo de fluoro, o R1 es un ciclopropilo o ciclopropilmetilo, y R2 es metilo o etilo; estos compuestos son utiles como agentes antibacterianos.
MX2007012386A 2005-04-06 2006-03-27 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacterianos. MX2007012386A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66871505P 2005-04-06 2005-04-06
US68403305P 2005-05-24 2005-05-24
PCT/IB2006/000954 WO2006106427A1 (en) 2005-04-06 2006-03-27 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
MX2007012386A true MX2007012386A (es) 2007-11-07

Family

ID=36636389

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007012386A MX2007012386A (es) 2005-04-06 2006-03-27 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacterianos.

Country Status (21)

Country Link
US (1) US7435751B2 (es)
EP (1) EP1869030A1 (es)
JP (1) JP2008534672A (es)
KR (1) KR20070108938A (es)
AP (1) AP2007004172A0 (es)
AR (1) AR053839A1 (es)
AU (1) AU2006231919A1 (es)
BR (1) BRPI0610533A2 (es)
CA (1) CA2603899A1 (es)
CR (1) CR9417A (es)
DO (1) DOP2006000080A (es)
GT (1) GT200600133A (es)
IL (1) IL186119A0 (es)
MX (1) MX2007012386A (es)
NL (1) NL1031525C2 (es)
NO (1) NO20075505L (es)
PE (1) PE20061301A1 (es)
TN (1) TNSN07373A1 (es)
TW (1) TW200716101A (es)
UY (1) UY29452A1 (es)
WO (1) WO2006106427A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006016221A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxazolidinones containing oxindoles as antibacterial agents
KR100891485B1 (ko) 2007-10-29 2009-04-02 주식회사 만도 디스크 브레이크의 주차브레이크 장치

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929303T2 (de) 1988-09-15 2002-05-02 Upjohn Co 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
DE4425613A1 (de) 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
US6015429A (en) * 1994-09-08 2000-01-18 Gore Enterprise Holdings, Inc. Procedures for introducing stents and stent-grafts
DE19649095A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue Heteroaryl-Oxazolidinone
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU3345599A (en) 1998-04-14 1999-11-01 Samsung Fine Chemicals Co., Ltd. A process for preparing chiral (s)-2,3-disubstituted-1-propylamine derivatives
AU1379900A (en) 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel substituted phenyloxazolidone derivatives
CN1322204A (zh) 1998-11-27 2001-11-14 法玛西雅厄普约翰美国公司 具有硫代羰基官能团的噁唑烷酮抗菌剂
PT1181288E (pt) 1999-05-27 2003-12-31 Upjohn Co Oxazolidinonas biciclicas como agentes antibacterianos
DE60118241T2 (de) 2000-10-17 2006-12-28 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonverbindungen
US20050032861A1 (en) 2001-04-07 2005-02-10 Betts Michael John Oxazolidines containing a sulfonimid group as antibiotics
DE60222645T2 (de) 2001-04-20 2008-07-17 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonen
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
WO2006016221A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxazolidinones containing oxindoles as antibacterial agents

Also Published As

Publication number Publication date
PE20061301A1 (es) 2007-02-09
GT200600133A (es) 2006-11-29
CR9417A (es) 2007-12-04
NL1031525C2 (nl) 2007-01-30
TW200716101A (en) 2007-05-01
KR20070108938A (ko) 2007-11-13
CA2603899A1 (en) 2006-10-12
EP1869030A1 (en) 2007-12-26
NL1031525A1 (nl) 2006-10-09
DOP2006000080A (es) 2006-12-15
TNSN07373A1 (fr) 2009-03-17
NO20075505L (no) 2007-10-31
US20060229349A1 (en) 2006-10-12
WO2006106427A8 (en) 2007-12-06
IL186119A0 (en) 2008-01-20
BRPI0610533A2 (pt) 2010-06-29
US7435751B2 (en) 2008-10-14
AR053839A1 (es) 2007-05-23
WO2006106427A1 (en) 2006-10-12
AP2007004172A0 (en) 2007-10-31
JP2008534672A (ja) 2008-08-28
UY29452A1 (es) 2006-11-30
AU2006231919A1 (en) 2006-10-12

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