NO151622C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive carboxyalkyldipeptider - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive carboxyalkyldipeptider

Info

Publication number
NO151622C
NO151622C NO794010A NO794010A NO151622C NO 151622 C NO151622 C NO 151622C NO 794010 A NO794010 A NO 794010A NO 794010 A NO794010 A NO 794010A NO 151622 C NO151622 C NO 151622C
Authority
NO
Norway
Prior art keywords
dipptides
carboxyal
cold
preparation
therapeutically active
Prior art date
Application number
NO794010A
Other languages
English (en)
Norwegian (no)
Other versions
NO151622B (no
NO794010L (no
Inventor
Arthur A Patchett
Elbert E Harris
Matthew J Wyvratt
Edward W Tristram
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25513965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO151622(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO794010L publication Critical patent/NO794010L/no
Publication of NO151622B publication Critical patent/NO151622B/no
Publication of NO151622C publication Critical patent/NO151622C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO794010A 1978-12-11 1979-12-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive carboxyalkyldipeptider NO151622C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96824978A 1978-12-11 1978-12-11

Publications (3)

Publication Number Publication Date
NO794010L NO794010L (no) 1980-06-12
NO151622B NO151622B (no) 1985-01-28
NO151622C true NO151622C (no) 1985-05-08

Family

ID=25513965

Family Applications (3)

Application Number Title Priority Date Filing Date
NO794010A NO151622C (no) 1978-12-11 1979-12-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive carboxyalkyldipeptider
NO1995007C NO1995007I1 (no) 1978-12-11 1995-08-02 Hydroklorthiazid og lisinopril/((S)-1-[N<O>2</O>-(1-carboxy-3-fenyl-propyl)-L-lysyl]-L-prolin)
NO1996004C NO1996004I1 (no) 1978-12-11 1996-02-23 Hydroklorthiazid og enalapril ((S)-1-[N-[1-(etoksykarbonyl)-3-fenylpropyl]-L-alanyl]-prolin)

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO1995007C NO1995007I1 (no) 1978-12-11 1995-08-02 Hydroklorthiazid og lisinopril/((S)-1-[N<O>2</O>-(1-carboxy-3-fenyl-propyl)-L-lysyl]-L-prolin)
NO1996004C NO1996004I1 (no) 1978-12-11 1996-02-23 Hydroklorthiazid og enalapril ((S)-1-[N-[1-(etoksykarbonyl)-3-fenylpropyl]-L-alanyl]-prolin)

Country Status (33)

Country Link
US (2) US4374829A (OSRAM)
EP (1) EP0012401B1 (OSRAM)
JP (3) JPS5581845A (OSRAM)
KR (3) KR850000847B1 (OSRAM)
AR (1) AR231971A1 (OSRAM)
AU (1) AU530380B2 (OSRAM)
BG (6) BG38787A3 (OSRAM)
CA (4) CA1302005C (OSRAM)
CS (1) CS237311B2 (OSRAM)
DD (1) DD148770A5 (OSRAM)
DE (2) DE2966767D1 (OSRAM)
DK (1) DK165455C (OSRAM)
EG (1) EG14182A (OSRAM)
ES (2) ES8101540A1 (OSRAM)
FI (1) FI68405C (OSRAM)
GR (1) GR72251B (OSRAM)
HK (1) HK27487A (OSRAM)
HU (1) HU182902B (OSRAM)
IE (1) IE48922B1 (OSRAM)
IL (1) IL58849A (OSRAM)
LU (1) LU90173I2 (OSRAM)
MA (1) MA18664A1 (OSRAM)
NL (4) NL930006I2 (OSRAM)
NO (3) NO151622C (OSRAM)
NZ (1) NZ192312A (OSRAM)
PH (1) PH24268A (OSRAM)
PL (2) PL126126B1 (OSRAM)
PT (1) PT70542A (OSRAM)
RO (4) RO80264A (OSRAM)
SU (1) SU1287756A3 (OSRAM)
YU (3) YU42655B (OSRAM)
ZA (1) ZA796688B (OSRAM)
ZW (1) ZW24479A1 (OSRAM)

Families Citing this family (399)

* Cited by examiner, † Cited by third party
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US4616029A (en) * 1979-12-07 1986-10-07 Adir Perhydromdole-2-carboxylic acids as antihypertensives
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