NO152841C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner.

Info

Publication number
NO152841C
NO152841C NO801796A NO801796A NO152841C NO 152841 C NO152841 C NO 152841C NO 801796 A NO801796 A NO 801796A NO 801796 A NO801796 A NO 801796A NO 152841 C NO152841 C NO 152841C
Authority
NO
Norway
Prior art keywords
aroylimidazol
ones
preparation
therapeutically active
active new
Prior art date
Application number
NO801796A
Other languages
English (en)
Other versions
NO152841B (no
NO801796L (no
Inventor
Richard A Schnettler
Richard C Dage
J Martin Grisar
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO152841(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of NO801796L publication Critical patent/NO801796L/no
Publication of NO152841B publication Critical patent/NO152841B/no
Publication of NO152841C publication Critical patent/NO152841C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO801796A 1979-06-18 1980-06-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner. NO152841C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (3)

Publication Number Publication Date
NO801796L NO801796L (no) 1980-12-19
NO152841B NO152841B (no) 1985-08-19
NO152841C true NO152841C (no) 1985-11-27

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
NO801796A NO152841C (no) 1979-06-18 1980-06-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner.

Country Status (20)

Country Link
AT (1) AT375349B (no)
AU (1) AU532783B2 (no)
CA (1) CA1132554A (no)
CH (1) CH646155A5 (no)
DE (1) DE3021792A1 (no)
DK (1) DK160269C (no)
ES (1) ES492255A0 (no)
FR (1) FR2459233A1 (no)
GB (1) GB2055364B (no)
HK (1) HK61486A (no)
HU (1) HU186736B (no)
IE (1) IE50646B1 (no)
IL (1) IL60243A (no)
IT (1) IT1143922B (no)
MY (1) MY8600709A (no)
NL (2) NL193752C (no)
NO (1) NO152841C (no)
NZ (1) NZ193935A (no)
PH (1) PH18683A (no)
SE (2) SE447107B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
JPS57185266A (en) * 1981-05-04 1982-11-15 Merrell Dow Pharma 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazole- 2-one
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329470A (en) 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2560528A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
WO2005092333A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
ZA200804550B (en) 2005-11-09 2009-08-26 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8034782B2 (en) 2008-07-16 2011-10-11 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2828346C (en) 2011-03-01 2021-01-26 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
CN105979959B (zh) 2013-08-09 2021-11-30 阿德利克斯公司 用于抑制磷酸盐转运的化合物和方法
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
DK160269C (da) 1991-07-22
ES8105299A1 (es) 1981-06-01
AU532783B2 (en) 1983-10-13
HK61486A (en) 1986-08-29
NL300015I2 (nl) 2000-10-02
NL300015I1 (nl) 2000-11-01
SE447107B (sv) 1986-10-27
CA1132554A (en) 1982-09-28
IL60243A (en) 1987-01-30
SE8501452L (sv) 1985-03-25
SE464559B (sv) 1991-05-13
IE50646B1 (en) 1986-06-11
CH646155A5 (de) 1984-11-15
NL193752B (nl) 2000-05-01
NO152841B (no) 1985-08-19
ES492255A0 (es) 1981-06-01
DK259080A (da) 1980-12-19
PH18683A (en) 1985-08-29
FR2459233B1 (no) 1983-09-23
GB2055364B (en) 1983-06-08
MY8600709A (en) 1986-12-31
DE3021792C2 (no) 1989-08-10
HU186736B (en) 1985-09-30
ATA314280A (de) 1983-12-15
NO801796L (no) 1980-12-19
DE3021792A1 (de) 1981-01-22
SE8004253L (sv) 1980-12-19
SE8501452D0 (sv) 1985-03-25
DK160269B (da) 1991-02-18
IT8048997A0 (it) 1980-06-17
NZ193935A (en) 1985-05-31
AU5911880A (en) 1981-01-08
NL8003498A (nl) 1980-12-22
IL60243A0 (en) 1980-09-16
NL193752C (nl) 2000-09-04
FR2459233A1 (fr) 1981-01-09
GB2055364A (en) 1981-03-04
AT375349B (de) 1984-07-25
IT1143922B (it) 1986-10-29
IE801162L (en) 1980-12-18

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