IL60243A0 - Novel 4-aroylimidazol-2-ones - Google Patents

Novel 4-aroylimidazol-2-ones

Info

Publication number
IL60243A0
IL60243A0 IL60243A IL6024380A IL60243A0 IL 60243 A0 IL60243 A0 IL 60243A0 IL 60243 A IL60243 A IL 60243A IL 6024380 A IL6024380 A IL 6024380A IL 60243 A0 IL60243 A0 IL 60243A0
Authority
IL
Israel
Prior art keywords
aroylimidazol
ones
novel
Prior art date
Application number
IL60243A
Other versions
IL60243A (en
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL60243(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of IL60243A0 publication Critical patent/IL60243A0/en
Publication of IL60243A publication Critical patent/IL60243A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL60243A 1979-06-18 1980-06-06 Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation IL60243A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (2)

Publication Number Publication Date
IL60243A0 true IL60243A0 (en) 1980-09-16
IL60243A IL60243A (en) 1987-01-30

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60243A IL60243A (en) 1979-06-18 1980-06-06 Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation

Country Status (20)

Country Link
AT (1) AT375349B (en)
AU (1) AU532783B2 (en)
CA (1) CA1132554A (en)
CH (1) CH646155A5 (en)
DE (1) DE3021792A1 (en)
DK (1) DK160269C (en)
ES (1) ES8105299A1 (en)
FR (1) FR2459233A1 (en)
GB (1) GB2055364B (en)
HK (1) HK61486A (en)
HU (1) HU186736B (en)
IE (1) IE50646B1 (en)
IL (1) IL60243A (en)
IT (1) IT1143922B (en)
MY (1) MY8600709A (en)
NL (2) NL193752C (en)
NO (1) NO152841C (en)
NZ (1) NZ193935A (en)
PH (1) PH18683A (en)
SE (2) SE447107B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
AU549872B2 (en) * 1981-05-04 1986-02-20 Merrell Dow Pharmaceuticals Inc. 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
WO2005092332A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US20060030611A1 (en) * 2004-03-22 2006-02-09 Myogen, Inc. Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases
AU2006311577B2 (en) 2005-11-09 2013-02-07 Zalicus Inc. Methods, compositions, and kits for the treatment of medical conditions
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (en) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc USEFUL CYCLASS GUANILATE AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS.
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (en) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. METHOD FOR OBTAINING GUANYLATZCLAZE AGONISTS C
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP6499591B2 (en) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists for use in colon lavage
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists and uses thereof
CN105764916B (en) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 Ultrapure agonists of guanylate cyclase C, methods of making and using the same
EP3492106B1 (en) 2013-08-09 2021-02-17 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP3972599B1 (en) 2019-05-21 2025-10-22 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (en) * 2022-03-03 2023-12-22 曲靖师范学院 Method for preparing 4-iodo-N-aryl pyrazole compound by iodine-promoted oxidation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
IE801162L (en) 1980-12-18
ATA314280A (en) 1983-12-15
NL300015I2 (en) 2000-10-02
NL300015I1 (en) 2000-11-01
SE464559B (en) 1991-05-13
PH18683A (en) 1985-08-29
ES492255A0 (en) 1981-06-01
DK160269C (en) 1991-07-22
DK259080A (en) 1980-12-19
GB2055364A (en) 1981-03-04
MY8600709A (en) 1986-12-31
DK160269B (en) 1991-02-18
AT375349B (en) 1984-07-25
NO152841C (en) 1985-11-27
HK61486A (en) 1986-08-29
DE3021792A1 (en) 1981-01-22
GB2055364B (en) 1983-06-08
AU5911880A (en) 1981-01-08
SE8004253L (en) 1980-12-19
NO152841B (en) 1985-08-19
CH646155A5 (en) 1984-11-15
NO801796L (en) 1980-12-19
IL60243A (en) 1987-01-30
FR2459233B1 (en) 1983-09-23
NZ193935A (en) 1985-05-31
FR2459233A1 (en) 1981-01-09
AU532783B2 (en) 1983-10-13
HU186736B (en) 1985-09-30
SE8501452D0 (en) 1985-03-25
IE50646B1 (en) 1986-06-11
ES8105299A1 (en) 1981-06-01
DE3021792C2 (en) 1989-08-10
NL8003498A (en) 1980-12-22
CA1132554A (en) 1982-09-28
IT8048997A0 (en) 1980-06-17
IT1143922B (en) 1986-10-29
NL193752B (en) 2000-05-01
SE8501452L (en) 1985-03-25
NL193752C (en) 2000-09-04
SE447107B (en) 1986-10-27

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Legal Events

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