DK160269C - METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF

Info

Publication number
DK160269C
DK160269C DK259080A DK259080A DK160269C DK 160269 C DK160269 C DK 160269C DK 259080 A DK259080 A DK 259080A DK 259080 A DK259080 A DK 259080A DK 160269 C DK160269 C DK 160269C
Authority
DK
Denmark
Prior art keywords
oner
aroyl
imidazol
dihydro
analogue
Prior art date
Application number
DK259080A
Other languages
Danish (da)
Other versions
DK160269B (en
DK259080A (en
Inventor
Richard A Schnettler
Richard C Dage
J Martin Grisar
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK160269(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DK259080A publication Critical patent/DK259080A/en
Publication of DK160269B publication Critical patent/DK160269B/en
Application granted granted Critical
Publication of DK160269C publication Critical patent/DK160269C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK259080A 1979-06-18 1980-06-17 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF DK160269C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US4980879 1979-06-18
US11920780A 1980-02-07 1980-02-07
US11920780 1980-02-07

Publications (3)

Publication Number Publication Date
DK259080A DK259080A (en) 1980-12-19
DK160269B DK160269B (en) 1991-02-18
DK160269C true DK160269C (en) 1991-07-22

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
DK259080A DK160269C (en) 1979-06-18 1980-06-17 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF

Country Status (20)

Country Link
AT (1) AT375349B (en)
AU (1) AU532783B2 (en)
CA (1) CA1132554A (en)
CH (1) CH646155A5 (en)
DE (1) DE3021792A1 (en)
DK (1) DK160269C (en)
ES (1) ES492255A0 (en)
FR (1) FR2459233A1 (en)
GB (1) GB2055364B (en)
HK (1) HK61486A (en)
HU (1) HU186736B (en)
IE (1) IE50646B1 (en)
IL (1) IL60243A (en)
IT (1) IT1143922B (en)
MY (1) MY8600709A (en)
NL (2) NL193752C (en)
NO (1) NO152841C (en)
NZ (1) NZ193935A (en)
PH (1) PH18683A (en)
SE (2) SE447107B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329470A (en) 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
AU549872B2 (en) * 1981-05-04 1986-02-20 Merrell Dow Pharmaceuticals Inc. 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1737448A1 (en) * 2004-03-22 2007-01-03 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
JP2007530566A (en) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド (R) -Enoximone sulfoxide and its use in the treatment of PDE-III mediated diseases
EP1956906A4 (en) 2005-11-09 2009-12-30 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (en) 2011-03-01 2018-10-19 辛纳吉制药公司 The method for preparing guanosine cyclic mono-phosphate agonist
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP6499591B2 (en) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists for use in colon lavage
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists in combination with other drugs
RS65632B1 (en) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
JP2022533251A (en) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド Combinations to lower serum phosphate in patients
CN114539157B (en) * 2022-03-03 2023-12-22 曲靖师范学院 Method for preparing 4-iodo-N-aryl pyrazole compound by iodine-promoted oxidation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
HK61486A (en) 1986-08-29
NO152841B (en) 1985-08-19
IE50646B1 (en) 1986-06-11
IE801162L (en) 1980-12-18
NZ193935A (en) 1985-05-31
IT8048997A0 (en) 1980-06-17
SE447107B (en) 1986-10-27
DK160269B (en) 1991-02-18
FR2459233B1 (en) 1983-09-23
MY8600709A (en) 1986-12-31
NL193752B (en) 2000-05-01
NL8003498A (en) 1980-12-22
SE8501452D0 (en) 1985-03-25
NO152841C (en) 1985-11-27
AT375349B (en) 1984-07-25
AU532783B2 (en) 1983-10-13
CH646155A5 (en) 1984-11-15
IT1143922B (en) 1986-10-29
HU186736B (en) 1985-09-30
GB2055364B (en) 1983-06-08
NL193752C (en) 2000-09-04
NL300015I2 (en) 2000-10-02
DE3021792C2 (en) 1989-08-10
DK259080A (en) 1980-12-19
AU5911880A (en) 1981-01-08
SE8501452L (en) 1985-03-25
NL300015I1 (en) 2000-11-01
NO801796L (en) 1980-12-19
FR2459233A1 (en) 1981-01-09
ES8105299A1 (en) 1981-06-01
DE3021792A1 (en) 1981-01-22
ES492255A0 (en) 1981-06-01
GB2055364A (en) 1981-03-04
SE8004253L (en) 1980-12-19
CA1132554A (en) 1982-09-28
IL60243A (en) 1987-01-30
IL60243A0 (en) 1980-09-16
PH18683A (en) 1985-08-29
ATA314280A (en) 1983-12-15
SE464559B (en) 1991-05-13

Similar Documents

Publication Publication Date Title
DK160269C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF
DK149308C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF TRANS-4-PHENYL-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS.
DK151884C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 3- (1-IMIDAZOLYLALKYL) INCIDENTAL OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS THEREOF
DK155048C (en) METHOD OF ANALOGUE FOR PREPARING 1,8-NAPHTHYRIDE COMPOUNDS
DK156001C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF MERCAPTOS-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES
DK156825C (en) ANALOGUE PROCEDURE FOR PREPARING A BASIC ETHER OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT OR QUATERNARY SALT THEREOF
DK148477C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF TETRAHYDROPYRIDINYLIN DERIVATIVE OR ADDITIONAL SALTS THEREOF
DK145260C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 4-ACYLAMINO-PHENYL-ETHANOLAMINES OR ACID ADDITION SALTS
DK152114C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF PROPENYLAMINES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK148904C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF ANALGETICALLY EFFECTIVE ENKEPHALIN ANALOGUE PENTAPEPTIDAMIDES OR PHARMACEUTICAL ACCEPTABLE NON-TOXIC ACID ADDITION SALTS THEREOF
DK160045C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 4-OXO-4H-PYRIDOOE1,2-AAAPYRIMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS THEREOF
DK149846C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF N, N'-BIS-TETRAHYDRO-ISOQUINOLYLD DISULPHONYLIMIDES
DK157862C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF IMIDAZOLYLPHENYLAMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS
DK159119C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF ACID ADDITION SALTS OF 3ALFA-ACYLOXY-2BETA, 16BETA-DIPIPERIDINO-5ALFA ANDROSTAND DERIVATIVES, AND PROCEDURES FOR THE PREPARATION OF PHARMACEUTICAL PRODUCTS
DK158658C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 9-AMINOAL COOLFluorens OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK146281C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6-FLUORO-N-2-IMIDAZOLIDINYLIDE-BENZAMINE OR ACID ADDITION SALTS.
DK151805C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 20,21-DI-NOR-EBURNAMENIN DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ADDITIONAL SALTS THEREOF
DK145263C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF IMIDAZOTHIAZINES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK152677C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 4'-O-TETRA-HYDROPYRANYLADRIAMYCINE OR A POISONOUS ACID ADDITION SALT
DK149625C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF N-SUBSTITUTED (8-HALOGEN OR TRIFLUORMETHYL-4-QUINOLYLAMINO) -BENZAMIDES OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT
DK152427C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 4-THIOMETHYLPYRIDINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS THEREOF
DK150197C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2-SUBSTITUTED 1-AMINOAL COXIMINO CYCLOALKANES OR AN ACID ADDITION SALT OR QUATERNATE AMMONIUM DERIVATIVE THEREOF
DK148903C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF ENKEPHALIN ANALOGUE PENTAPEPTIDE DERIVATIVES OR ACID ADDITION SALTS.
DK152491C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERENTIC PHENOXYPROPANOLAMINES OR PHARMACEUTICAL APPLICABLE SALTS THEREOF
DK157021C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF 2,3-POLYMETHYLENE-4-OXO-4H-PYRIDO- OR -AZEPINOOE1,2-AAAPYRIMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS OR QUATERA SALTS

Legal Events

Date Code Title Description
PUP Patent expired