GB2055364B - 4-aroylimidazol-2-ones - Google Patents

4-aroylimidazol-2-ones

Info

Publication number
GB2055364B
GB2055364B GB8019898A GB8019898A GB2055364B GB 2055364 B GB2055364 B GB 2055364B GB 8019898 A GB8019898 A GB 8019898A GB 8019898 A GB8019898 A GB 8019898A GB 2055364 B GB2055364 B GB 2055364B
Authority
GB
United Kingdom
Prior art keywords
aroylimidazol
ones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8019898A
Other versions
GB2055364A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2055364(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of GB2055364A publication Critical patent/GB2055364A/en
Application granted granted Critical
Publication of GB2055364B publication Critical patent/GB2055364B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
GB8019898A 1979-06-18 1980-06-18 4-aroylimidazol-2-ones Expired GB2055364B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (2)

Publication Number Publication Date
GB2055364A GB2055364A (en) 1981-03-04
GB2055364B true GB2055364B (en) 1983-06-08

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8019898A Expired GB2055364B (en) 1979-06-18 1980-06-18 4-aroylimidazol-2-ones

Country Status (20)

Country Link
AT (1) AT375349B (en)
AU (1) AU532783B2 (en)
CA (1) CA1132554A (en)
CH (1) CH646155A5 (en)
DE (1) DE3021792A1 (en)
DK (1) DK160269C (en)
ES (1) ES8105299A1 (en)
FR (1) FR2459233A1 (en)
GB (1) GB2055364B (en)
HK (1) HK61486A (en)
HU (1) HU186736B (en)
IE (1) IE50646B1 (en)
IL (1) IL60243A (en)
IT (1) IT1143922B (en)
MY (1) MY8600709A (en)
NL (2) NL193752C (en)
NO (1) NO152841C (en)
NZ (1) NZ193935A (en)
PH (1) PH18683A (en)
SE (2) SE447107B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
JPS57185266A (en) * 1981-05-04 1982-11-15 Merrell Dow Pharma 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazole- 2-one
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007530566A (en) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド (R) -Enoximone sulfoxide and its use in the treatment of PDE-III mediated diseases
EP1737448A1 (en) * 2004-03-22 2007-01-03 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
JP2009514969A (en) 2005-11-09 2009-04-09 コンビナトアールエックス インコーポレーティッド Methods, compositions, and kits for treating medical conditions
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2522968T3 (en) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (en) 2011-03-01 2018-10-19 辛纳吉制药公司 The method for preparing guanosine cyclic mono-phosphate agonist
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
WO2014131024A2 (en) 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (en) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド Ultra high purity agonist of guanylate cyclase C, method for producing and using the same
MX2016001714A (en) 2013-08-09 2016-10-03 Ardelyx Inc Compounds and methods for inhibiting phosphate transport.
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (en) * 2022-03-03 2023-12-22 曲靖师范学院 Method for preparing 4-iodo-N-aryl pyrazole compound by iodine-promoted oxidation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
NL8003498A (en) 1980-12-22
SE8501452D0 (en) 1985-03-25
NO152841B (en) 1985-08-19
NL193752C (en) 2000-09-04
PH18683A (en) 1985-08-29
GB2055364A (en) 1981-03-04
HU186736B (en) 1985-09-30
IE50646B1 (en) 1986-06-11
NZ193935A (en) 1985-05-31
NL300015I2 (en) 2000-10-02
SE447107B (en) 1986-10-27
SE464559B (en) 1991-05-13
MY8600709A (en) 1986-12-31
IL60243A0 (en) 1980-09-16
IE801162L (en) 1980-12-18
AU5911880A (en) 1981-01-08
NL193752B (en) 2000-05-01
DE3021792A1 (en) 1981-01-22
AT375349B (en) 1984-07-25
HK61486A (en) 1986-08-29
DK160269C (en) 1991-07-22
ES492255A0 (en) 1981-06-01
IT1143922B (en) 1986-10-29
ATA314280A (en) 1983-12-15
FR2459233A1 (en) 1981-01-09
FR2459233B1 (en) 1983-09-23
NO801796L (en) 1980-12-19
CH646155A5 (en) 1984-11-15
DK259080A (en) 1980-12-19
SE8501452L (en) 1985-03-25
NO152841C (en) 1985-11-27
ES8105299A1 (en) 1981-06-01
NL300015I1 (en) 2000-11-01
SE8004253L (en) 1980-12-19
DE3021792C2 (en) 1989-08-10
IT8048997A0 (en) 1980-06-17
CA1132554A (en) 1982-09-28
DK160269B (en) 1991-02-18
IL60243A (en) 1987-01-30
AU532783B2 (en) 1983-10-13

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Legal Events

Date Code Title Description
CTFF Supplementary protection certificate filed

Free format text: SPC/GB93/120, 930629

CTFG Supplementary protection certificate granted

Free format text: SPC/GB93/120, 931210, EXPIRES:20021026

CTFE Supplementary protection certificate entered into force

Free format text: SPC/GB93/120, 20000618, EXPIRES: 20021026

PE20 Patent expired after termination of 20 years

Effective date: 20000617

SPCE Supplementary protection certificate expired

Spc suppl protection certif: SPC/GB93/120

Expiry date: 20021026