IL60243A - Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation - Google Patents
Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparationInfo
- Publication number
- IL60243A IL60243A IL60243A IL6024380A IL60243A IL 60243 A IL60243 A IL 60243A IL 60243 A IL60243 A IL 60243A IL 6024380 A IL6024380 A IL 6024380A IL 60243 A IL60243 A IL 60243A
- Authority
- IL
- Israel
- Prior art keywords
- aroylimidazol
- heteroaroyl
- ones
- preparation
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4980879A | 1979-06-18 | 1979-06-18 | |
US11920780A | 1980-02-07 | 1980-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL60243A0 IL60243A0 (en) | 1980-09-16 |
IL60243A true IL60243A (en) | 1987-01-30 |
Family
ID=26727558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL60243A IL60243A (en) | 1979-06-18 | 1980-06-06 | Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation |
Country Status (20)
Country | Link |
---|---|
AT (1) | AT375349B (xx) |
AU (1) | AU532783B2 (xx) |
CA (1) | CA1132554A (xx) |
CH (1) | CH646155A5 (xx) |
DE (1) | DE3021792A1 (xx) |
DK (1) | DK160269C (xx) |
ES (1) | ES492255A0 (xx) |
FR (1) | FR2459233A1 (xx) |
GB (1) | GB2055364B (xx) |
HK (1) | HK61486A (xx) |
HU (1) | HU186736B (xx) |
IE (1) | IE50646B1 (xx) |
IL (1) | IL60243A (xx) |
IT (1) | IT1143922B (xx) |
MY (1) | MY8600709A (xx) |
NL (2) | NL193752C (xx) |
NO (1) | NO152841C (xx) |
NZ (1) | NZ193935A (xx) |
PH (1) | PH18683A (xx) |
SE (2) | SE447107B (xx) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH18106A (en) * | 1981-02-18 | 1985-03-21 | Merrell Dow Pharma | Novel-4-aroylimidazol-2-ones |
US4405628A (en) * | 1981-03-05 | 1983-09-20 | Merrell Dow Pharmaceuticals Inc. | 4-Pyridylimidazolones and method of use |
US4526981A (en) * | 1981-05-04 | 1985-07-02 | Merrell Dow Pharmaceuticals Inc. | [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates |
US4371737A (en) * | 1981-05-04 | 1983-02-01 | Merrell Dow Pharmaceuticals Inc. | 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives |
GB2097792B (en) * | 1981-05-04 | 1985-01-03 | Merrell Dow Pharma | 1,3-dihydro-2h-imidazol-2-ones |
US4329470A (en) | 1981-05-04 | 1982-05-11 | Merrell Dow Pharmaceuticals Inc. | 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives |
US4329471A (en) * | 1981-05-04 | 1982-05-11 | Merrell Dow Pharmaceuticals Inc. | 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones |
US4381393A (en) * | 1981-05-04 | 1983-04-26 | Merrell Dow Pharmaceuticals Inc. | 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones |
US4367236A (en) | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
US4410540A (en) * | 1981-11-04 | 1983-10-18 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic 4-aroylimidazolidin-2-ones |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
JP2007530563A (ja) * | 2004-03-22 | 2007-11-01 | ミオゲン インコーポレイティッド | (s)−エノキシモンスルホキシドおよびpde−iii媒介疾患の治療におけるその使用 |
US20060030611A1 (en) * | 2004-03-22 | 2006-02-09 | Myogen, Inc. | Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases |
US8067433B2 (en) | 2005-11-09 | 2011-11-29 | Zalicus Inc. | Methods, compositions, and kits for the treatment of ophthalmic disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2828346C (en) | 2011-03-01 | 2021-01-26 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
KR20160042039A (ko) | 2013-08-09 | 2016-04-18 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
CN114539157B (zh) * | 2022-03-03 | 2023-12-22 | 曲靖师范学院 | 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2441933A (en) * | 1945-07-30 | 1948-05-18 | Hoffmann La Roche | Substituted imidazolones and process of making them |
-
1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 SE SE8004253A patent/SE447107B/sv not_active IP Right Cessation
- 1980-06-06 IL IL60243A patent/IL60243A/xx unknown
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-09 ES ES492255A patent/ES492255A0/es active Granted
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/de active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/de not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-16 CH CH462780A patent/CH646155A5/de not_active IP Right Cessation
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 FR FR8013434A patent/FR2459233A1/fr active Granted
- 1980-06-17 HU HU801506A patent/HU186736B/hu unknown
- 1980-06-17 NL NL8003498A patent/NL193752C/nl not_active IP Right Cessation
- 1980-06-17 IT IT48997/80A patent/IT1143922B/it active Protection Beyond IP Right Term
- 1980-06-17 NO NO801796A patent/NO152841C/no unknown
- 1980-06-17 DK DK259080A patent/DK160269C/da not_active IP Right Cessation
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
-
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/sv not_active IP Right Cessation
-
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/xx unknown
-
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL60243A (en) | Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation | |
DE3062094D1 (en) | Novel 1-aryl-2-acylamido-3-fluoro-1-propanols, their preparation and pharmaceutical compositions containing them | |
GB8315756D0 (en) | Preparation of activated pharmaceutical compositions | |
IL56411A (en) | Derivatives of 4-amino-5-alkylsulphonyl-ortho-anisamides,their preparation and pharmaceutical compositions containing them | |
IL59150A (en) | N-benzyl-imidazoles,their preparation and pharmaceutical compositions containing them | |
IL60086A (en) | Pyrimidine compounds,their preparation and pharmaceutical compositions containing them | |
IL59770A (en) | Pharmaceutical compositions containing 3-alkoxy-flavone derivatives,some novel compounds of this type and their preparation | |
DE3068678D1 (en) | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them | |
IL59180A (en) | Pharmaceutical compositions containing polysubstituted acrylophenones,certain such new compounds and their preparation | |
IL60678A0 (en) | 3-amino-syndone-imines, their preparation and pharmaceutical compositions containing them | |
IL60918A (en) | 6-pyridazinones,their preparation and pharmaceutical compositions containing them | |
IL61264A (en) | Dihydro-piperazinylpyrazolobenzodiazepine compounds,their preparation and pharmaceutical compositions containing them | |
IL60307A0 (en) | Alkoxybenzylpyridopyrimidines,their preparation and pharmaceutical compositions containing them | |
IL55254A0 (en) | Novel bis-isoquinolinium compounds,their preparation and pharmaceutical compositions containing them | |
IL61117A0 (en) | Acetoxymethyl-penem compounds and pharmaceutical compositions containing them | |
DE3064707D1 (en) | Sydnonimines, their preparation and pharmaceutical compositions containing them | |
IL60813A0 (en) | Heterocyclic compounds, their preparation and pharmaceutical compositions containing them | |
IL60115A (en) | Tri-substituted arylacrylophenones,their preparation and pharmaceutical compositions containing them | |
IL70508A (en) | Pharmaceutical compositions containing aralkyltriazole derivatives,some such novel compounds and their preparation | |
DE2966444D1 (en) | Benzopyranotriazoles, preparation of these compounds and pharmaceutical composition containing them | |
IL56404A0 (en) | Novel analogs of h-endorphin, their preparation and pharmaceutical compositions containing them | |
NZ194331A (en) | 3-amino-1-benzoxepin-5(2h)-ones their preparation and pharmaceutical compositions containing them | |
IL57667A (en) | 2-azaergolines and 2-aza-8-ergolines,their preparation and pharmaceutical compositions containing them | |
DE2960503D1 (en) | Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them | |
IL56075A0 (en) | Novel arylaminoimidazoline derivatives,their preparation and pharmaceutical compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed |