MX386778B - Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia. - Google Patents

Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.

Info

Publication number
MX386778B
MX386778B MX2017011586A MX2017011586A MX386778B MX 386778 B MX386778 B MX 386778B MX 2017011586 A MX2017011586 A MX 2017011586A MX 2017011586 A MX2017011586 A MX 2017011586A MX 386778 B MX386778 B MX 386778B
Authority
MX
Mexico
Prior art keywords
lipodystrophy
methods
fatty liver
compositions
present
Prior art date
Application number
MX2017011586A
Other languages
English (en)
Spanish (es)
Other versions
MX2017011586A (es
Inventor
Christos Mantzoros
Original Assignee
Intekrin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intekrin Therapeutics Inc filed Critical Intekrin Therapeutics Inc
Publication of MX2017011586A publication Critical patent/MX2017011586A/es
Publication of MX386778B publication Critical patent/MX386778B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2017011586A 2015-03-09 2016-03-07 Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia. MX386778B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562130488P 2015-03-09 2015-03-09
PCT/US2016/021162 WO2016144862A1 (en) 2015-03-09 2016-03-07 Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy

Publications (2)

Publication Number Publication Date
MX2017011586A MX2017011586A (es) 2017-10-26
MX386778B true MX386778B (es) 2025-03-19

Family

ID=56879272

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017011586A MX386778B (es) 2015-03-09 2016-03-07 Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.
MX2021011949A MX2021011949A (es) 2015-03-09 2017-09-08 Metodos para el tratamiento de enfermedad de higado graso no alcoholico y/o lipodistrofia.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021011949A MX2021011949A (es) 2015-03-09 2017-09-08 Metodos para el tratamiento de enfermedad de higado graso no alcoholico y/o lipodistrofia.

Country Status (16)

Country Link
US (3) US10555929B2 (enExample)
EP (1) EP3267994A4 (enExample)
JP (2) JP2018507914A (enExample)
KR (2) KR20220070057A (enExample)
CN (1) CN107683135A (enExample)
AU (2) AU2016229982B2 (enExample)
BR (1) BR112017019170A2 (enExample)
CA (1) CA2979033A1 (enExample)
EA (1) EA201791982A1 (enExample)
HK (1) HK1249847A1 (enExample)
IL (1) IL254282A0 (enExample)
MA (1) MA42450A (enExample)
MX (2) MX386778B (enExample)
SG (2) SG11201707276PA (enExample)
TW (1) TWI769976B (enExample)
WO (1) WO2016144862A1 (enExample)

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SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
MX386778B (es) 2015-03-09 2025-03-19 Intekrin Therapeutics Inc Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
EP3534976A4 (en) 2016-11-04 2020-09-16 Children's Hospital Medical Center PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE
CA3045145A1 (en) 2016-12-05 2018-06-14 Children's Hospital Medical Center Colonic organoids and methods of making and using same
WO2018187350A1 (en) 2017-04-03 2018-10-11 Coherus Biosciences Inc. PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
WO2018191673A1 (en) 2017-04-14 2018-10-18 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
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GB201715654D0 (en) 2017-09-27 2017-11-08 Tdeltas Ltd Method of treatment
JP2020536529A (ja) 2017-10-10 2020-12-17 チルドレンズ ホスピタル メディカル センター 食道組織および／または臓器組成物およびそれを作製する方法
WO2019126626A1 (en) 2017-12-21 2019-06-27 Children's Hospital Medical Center Digitalized human organoids and methods of using same
EP3826652B1 (en) 2018-07-26 2026-02-25 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
EP3849568A4 (en) 2018-09-12 2022-06-15 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
GB2577723A (en) 2018-10-04 2020-04-08 Tdeltas Ltd Compounds for new use
JP2022516509A (ja) * 2018-12-31 2022-02-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 非アルコール性脂肪性肝疾患（ｎａｆｌｄ）を治療するための組成物および方法
WO2020205027A1 (en) * 2019-04-02 2020-10-08 Christos Mantzoros Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
WO2020205025A1 (en) * 2019-04-04 2020-10-08 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
EP3946334A1 (en) * 2019-04-04 2022-02-09 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
US20220193065A1 (en) * 2019-04-04 2022-06-23 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
US20220288054A1 (en) * 2019-04-04 2022-09-15 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
AU2020283048A1 (en) 2019-05-31 2021-12-23 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
EP3976066A4 (en) 2019-05-31 2023-06-28 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
WO2021076616A1 (en) * 2019-10-15 2021-04-22 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
JP2022104747A (ja) * 2020-12-29 2022-07-11 国立研究開発法人国立がん研究センター 抗ウイルス剤
CN118406749A (zh) * 2024-02-29 2024-07-30 安徽医科大学 Caveolin-1基因在制备预防、治疗或缓解非酒精性脂肪肝病的药物中的应用

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JP2022516509A (ja) 2018-12-31 2022-02-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 非アルコール性脂肪性肝疾患（ｎａｆｌｄ）を治療するための組成物および方法
WO2020205027A1 (en) 2019-04-02 2020-10-08 Christos Mantzoros Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
WO2020205025A1 (en) 2019-04-04 2020-10-08 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)
WO2021076616A1 (en) 2019-10-15 2021-04-22 Coherus Biosciences, Inc. Compositions and methods to treat non-alcoholic fatty liver diseases (nafld)

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HK1249847A1 (zh) 2018-11-16
US20200147036A1 (en) 2020-05-14
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AU2016229982B2 (en) 2020-06-18
US10555929B2 (en) 2020-02-11
WO2016144862A1 (en) 2016-09-15
AU2016229982A1 (en) 2017-09-21
BR112017019170A2 (pt) 2018-07-10
EP3267994A4 (en) 2018-10-31
KR20220070057A (ko) 2022-05-27
TWI769976B (zh) 2022-07-11
EP3267994A1 (en) 2018-01-17
AU2020233626A1 (en) 2020-10-08
MA42450A (fr) 2018-05-23
SG10202103552XA (en) 2021-05-28
KR20180006881A (ko) 2018-01-19
AU2020233626B2 (en) 2022-06-02
US10772865B2 (en) 2020-09-15
CN107683135A (zh) 2018-02-09
US20160263098A1 (en) 2016-09-15
TW201639571A (zh) 2016-11-16
JP2018507914A (ja) 2018-03-22
MX2021011949A (es) 2021-11-03
CA2979033A1 (en) 2016-09-15
US11400072B2 (en) 2022-08-02
MX2017011586A (es) 2017-10-26
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US20200383945A1 (en) 2020-12-10
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