MX2011012262A - 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak). - Google Patents

3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak).

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Publication number
MX2011012262A
MX2011012262A MX2011012262A MX2011012262A MX2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A MX 2011012262 A MX2011012262 A MX 2011012262A
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MX
Mexico
Prior art keywords
salt
compound
patient
pyrrolo
pyrazol
Prior art date
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MX2011012262A
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English (en)
Spanish (es)
Inventor
James D Rodgers
Yun-Long Li
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Incyte Corp
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Application filed by Incyte Corp filed Critical Incyte Corp
Publication of MX2011012262A publication Critical patent/MX2011012262A/es

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
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    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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MX2011012262A 2009-05-22 2010-05-21 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak). MX2011012262A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18058209P 2009-05-22 2009-05-22
PCT/US2010/035728 WO2010135621A1 (en) 2009-05-22 2010-05-21 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors

Publications (1)

Publication Number Publication Date
MX2011012262A true MX2011012262A (es) 2012-01-25

Family

ID=42246359

Family Applications (1)

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MX2011012262A MX2011012262A (es) 2009-05-22 2010-05-21 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il] octano-o heptano-nitrilo como inhibidores de cinasas janus (jak).

Country Status (36)

Country Link
US (3) US8604043B2 (https=)
EP (2) EP2432472B1 (https=)
JP (2) JP6172939B2 (https=)
KR (1) KR20120030447A (https=)
CN (2) CN106967070A (https=)
AR (1) AR076920A1 (https=)
AU (1) AU2010249443B2 (https=)
BR (1) BRPI1012108B8 (https=)
CA (1) CA2761954C (https=)
CL (1) CL2011002955A1 (https=)
CO (1) CO6470876A2 (https=)
CR (1) CR20110621A (https=)
CY (1) CY1122425T1 (https=)
DK (1) DK2432472T3 (https=)
EA (1) EA020494B1 (https=)
EC (1) ECSP11011534A (https=)
ES (1) ES2761300T3 (https=)
HR (1) HRP20192203T1 (https=)
HU (1) HUE046493T2 (https=)
IL (1) IL216359A (https=)
LT (1) LT2432472T (https=)
ME (1) ME03556B (https=)
MX (1) MX2011012262A (https=)
MY (1) MY161416A (https=)
NZ (1) NZ596374A (https=)
PE (1) PE20120371A1 (https=)
PL (1) PL2432472T3 (https=)
PT (1) PT2432472T (https=)
RS (1) RS59632B1 (https=)
SG (2) SG176111A1 (https=)
SI (1) SI2432472T1 (https=)
SM (1) SMT201900698T1 (https=)
TW (1) TWI484962B (https=)
UA (1) UA106078C2 (https=)
WO (1) WO2010135621A1 (https=)
ZA (1) ZA201108541B (https=)

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