KR20180028516A - 올리고뉴클레오티드 조성물 및 이의 방법 - Google Patents

올리고뉴클레오티드 조성물 및 이의 방법 Download PDF

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KR20180028516A
KR20180028516A KR1020187004483A KR20187004483A KR20180028516A KR 20180028516 A KR20180028516 A KR 20180028516A KR 1020187004483 A KR1020187004483 A KR 1020187004483A KR 20187004483 A KR20187004483 A KR 20187004483A KR 20180028516 A KR20180028516 A KR 20180028516A
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oligonucleotide
pattern
backbone
chiral
composition
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찬드라 바르기스
미나
네나드 스브르지카파
수소반 모하파트라
크리스토퍼 제이 프랜시스
그레고리 엘 버딘
안나 소콜로브스카
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웨이브 라이프 사이언시스 리미티드
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
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    • C12N2310/30—Chemical structure
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    • C12N2310/30—Chemical structure
    • C12N2310/34—Spatial arrangement of the modifications
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
    • C12N2310/3525—MOE, methoxyethoxy

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  • Chemical Kinetics & Catalysis (AREA)
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  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
KR1020187004483A 2015-07-22 2016-07-22 올리고뉴클레오티드 조성물 및 이의 방법 Withdrawn KR20180028516A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562195779P 2015-07-22 2015-07-22
US62/195,779 2015-07-22
US201562236847P 2015-10-02 2015-10-02
US62/236,847 2015-10-02
US201662331960P 2016-05-04 2016-05-04
US62/331,960 2016-05-04
PCT/US2016/043542 WO2017015555A1 (en) 2015-07-22 2016-07-22 Oligonucleotide compositions and methods thereof

Publications (1)

Publication Number Publication Date
KR20180028516A true KR20180028516A (ko) 2018-03-16

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KR1020187004483A Withdrawn KR20180028516A (ko) 2015-07-22 2016-07-22 올리고뉴클레오티드 조성물 및 이의 방법

Country Status (23)

Country Link
US (6) US10479995B2 (https=)
EP (3) EP3325017A4 (https=)
JP (6) JP7296724B2 (https=)
KR (1) KR20180028516A (https=)
CN (3) CN108135921B (https=)
AU (3) AU2016297155B2 (https=)
BR (1) BR112017028636A2 (https=)
CA (1) CA2989682A1 (https=)
CL (1) CL2018000145A1 (https=)
CO (1) CO2018001484A2 (https=)
CR (1) CR20180107A (https=)
EC (1) ECSP18010463A (https=)
HK (2) HK1255369A1 (https=)
IL (2) IL320434A (https=)
MA (1) MA43072A (https=)
MX (2) MX2018000796A (https=)
NI (1) NI201800009A (https=)
PE (1) PE20181174A1 (https=)
PH (1) PH12018500145A1 (https=)
SG (1) SG10201912900XA (https=)
SV (1) SV2018005619A (https=)
TW (1) TW201707711A (https=)
WO (2) WO2017015555A1 (https=)

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