KR20120014064A - 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도 - Google Patents

포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도 Download PDF

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KR20120014064A
KR20120014064A KR1020117031497A KR20117031497A KR20120014064A KR 20120014064 A KR20120014064 A KR 20120014064A KR 1020117031497 A KR1020117031497 A KR 1020117031497A KR 20117031497 A KR20117031497 A KR 20117031497A KR 20120014064 A KR20120014064 A KR 20120014064A
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South Korea
Prior art keywords
peptide
glucose
peptidase
activity
blood glucose
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Ceased
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KR1020117031497A
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Korean (ko)
Inventor
한스-울리히 데무트
프레트 로쉐
외른 슈미트
로버트 피. 폴리
크리스퍼토퍼 에이치. 에스. 미친토쉬
레이 에이. 피데르슨
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프로시디온 리미티드
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Application filed by 프로시디온 리미티드 filed Critical 프로시디온 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020117031497A 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도 Ceased KR20120014064A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19616486.9 1996-04-25
DE19616486.9A DE19616486C5 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
PCT/DE1997/000820 WO1997040832A1 (de) 1996-04-25 1997-04-24 Verwendung von dipeptidyl peptidase iv effektoren zur senkung des blutglukosespiegels in säugern

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107003160A Division KR20100036363A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도

Publications (1)

Publication Number Publication Date
KR20120014064A true KR20120014064A (ko) 2012-02-15

Family

ID=7792391

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020117031497A Ceased KR20120014064A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도
KR1020107003160A Ceased KR20100036363A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도
KR1020077015000A Expired - Fee Related KR100950722B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
KR1020057019835A Ceased KR20050104428A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
KR1019980707018A Expired - Lifetime KR100617676B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는 데 효과가 있는 이가펩티드성 펩티다아제의 활성 억제제의 용도

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020107003160A Ceased KR20100036363A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도
KR1020077015000A Expired - Fee Related KR100950722B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
KR1020057019835A Ceased KR20050104428A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
KR1019980707018A Expired - Lifetime KR100617676B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는 데 효과가 있는 이가펩티드성 펩티다아제의 활성 억제제의 용도

Country Status (21)

Country Link
US (1) US6303661B1 (cg-RX-API-DMAC7.html)
EP (3) EP1084705B1 (cg-RX-API-DMAC7.html)
JP (3) JP2001510442A (cg-RX-API-DMAC7.html)
KR (5) KR20120014064A (cg-RX-API-DMAC7.html)
CN (2) CN1132578C (cg-RX-API-DMAC7.html)
AT (1) ATE202705T1 (cg-RX-API-DMAC7.html)
AU (1) AU721477C (cg-RX-API-DMAC7.html)
CA (1) CA2252576C (cg-RX-API-DMAC7.html)
DE (5) DE19616486C5 (cg-RX-API-DMAC7.html)
DK (2) DK1084705T3 (cg-RX-API-DMAC7.html)
ES (2) ES2505665T3 (cg-RX-API-DMAC7.html)
FR (1) FR14C0089I1 (cg-RX-API-DMAC7.html)
GR (1) GR3036788T3 (cg-RX-API-DMAC7.html)
LT (3) LTPA2014045I1 (cg-RX-API-DMAC7.html)
LU (7) LU91334I2 (cg-RX-API-DMAC7.html)
NL (2) NL300280I2 (cg-RX-API-DMAC7.html)
NZ (1) NZ332707A (cg-RX-API-DMAC7.html)
PT (2) PT896538E (cg-RX-API-DMAC7.html)
RU (1) RU2189233C2 (cg-RX-API-DMAC7.html)
SI (1) SI1084705T1 (cg-RX-API-DMAC7.html)
WO (1) WO1997040832A1 (cg-RX-API-DMAC7.html)

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