KR20080103611A - 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 - Google Patents
처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 Download PDFInfo
- Publication number
- KR20080103611A KR20080103611A KR1020087027860A KR20087027860A KR20080103611A KR 20080103611 A KR20080103611 A KR 20080103611A KR 1020087027860 A KR1020087027860 A KR 1020087027860A KR 20087027860 A KR20087027860 A KR 20087027860A KR 20080103611 A KR20080103611 A KR 20080103611A
- Authority
- KR
- South Korea
- Prior art keywords
- cells
- tissue
- adipose tissue
- adipose
- stem cells
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/71—Suction drainage systems
- A61M1/76—Handpieces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
Abstract
Description
체중 지수 상태 | 얻어진 조직의 양 (g) | 총 세포 수율 |
보통 | 641±142 | 2.1±0.4 |
비만 | 1,225±173 | 2.4±0.5 |
p 값 | 0.03 | 0.6 |
Claims (21)
- 개체로부터 얻은 무손상(intact)의 탈응집되지 않은(non-disaggregated) 조직 단편을 포함하는 비처리 지방 조직을 포함하는 제1 성분과 혼합된, 탈응집된 지방 유래 줄기 세포를 포함하는 탈응집되고 농축된 지방 조직 세포를 포함하는 제2 성분을 포함하는 혼합물을 포함하고, 여기서, 상기 탈응집된 지방 유래 줄기 세포를 포함하는 탈응집되고 농축된 지방 조직 세포는 상기 개체로부터 얻은 것이고, 상기 제2 성분 중 탈응집된 지방 유래 줄기 세포의 빈도수는 상기 제2 성분 중 유핵 세포의 0.1% 이상인, 연조직 손상의 치료 또는 미용적 재건(cosmetic reconstruction)을 위한 약학 조성물.
- 제1항에 있어서, 상기 제2 지방 조직 성분이 성숙한 지방 세포 및 결합 조직이 없는, 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 포함하는 것인 약학 조성물.
- 제1항에 있어서, 상기 제2 성분 중의 탈응집된 지방 유래 줄기 세포의 빈도수가 약 2% 내지 약 12%인 약학 조성물.
- 제2항에 있어서, 상기 제2 성분 중의 줄기 세포의 양이 제2 성분 중의 세포 총량의 20%를 초과하는 것인 약학 조성물.
- 제2항에 있어서, 혼합물 중의 줄기 세포 농도가 제1 성분 중의 줄기 세포 농도보다 50% 이상 더 높은 것인 약학 조성물.
- 제2항에 있어서, 혼합물 중의 줄기 세포 농도가 제1 성분 중의 줄기 세포 농도보다 200% 이상 더 높은 것인 약학 조성물.
- 제2항에 있어서, 혼합물 중의 줄기 세포 농도가 제1 성분 중의 줄기 세포 농도보다 300% 이상 더 높은 것인 약학 조성물.
- 제1항에 있어서, 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포의 분화를 조절하도록 하는 양으로 존재하는 사이토카인 또는 성장 인자를 추가로 포함하는 약학 조성물.
- 제1항에 있어서, 상기 제2 성분이 분해된(dissociated) 지방 조직을 포함하는 것인 약학 조성물.
- 제1항에 있어서, 상기 제2 지방 조직 성분이 2개 이상의 별개의 부분들의 지방 조직 배합물을 포함하는 것인 약학 조성물.
- 제1항에 있어서, 상기 제2 지방 조직 성분이 일련의 세척 및 탈응집(disaggregation) 단계 또는 후-처리 세척/농축 단계로 처리된 것인 약학 조성물.
- 제1항에 있어서, 상기 제1 성분이 동결보존 물질을 포함하는 것인 약학 조성물.
- 제1항에 있어서, 상기 제2 성분이 동결보존 물질을 포함하는 것인 약학 조성물.
- 밀폐된 시스템 내에 존재하고, 지방 조직을 수용하도록 구조화된 조직 수집 용기;상기 조직 수집 용기 내에 위치하고, 지방 조직은 보유하고 지질, 혈액 및 염수는 통과시키도록 구조화된 제1 필터;상기 밀폐된 시스템 내에 존재하고, 상기 조직 수집 용기로부터 지방 유래 줄기 세포를 포함하는 지방 조직 세포를 수용하고 농축하도록 구조화된 세포 수집 용기;온도 조절 장치; 및지방 유래 줄기 세포를 포함하는 상기 농축된 지방 조직 세포의 무균 수거가 일어나도록 구조화된 출구를 포함하는, 자체 완비형 지방 유래 줄기 세포 처리 장치.
- 제14항에 있어서, 상기 온도 조절 장치가 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 냉각하도록 구조화된 것인 장치.
- 제14항에 있어서, 상기 온도 조절 장치가 상기 지방 조직 또는 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 가열하도록 구조화된 것인 장치.
- 제14항에 있어서, 밀폐 시스템을 유지하면서 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 비처리 지방 조직과 혼합하도록 구조화된 장치.
- 밀폐된 시스템 내에 존재하고, 지방 조직을 수용하도록 구조화된 조직 수집 용기;상기 조직 수집 용기 내에 위치하고, 지방 조직은 보유하고 지질, 혈액 및 염수는 통과시키도록 구조화된 제1 필터;상기 밀폐된 시스템 내에 존재하고, 상기 조직 수집 용기로부터 지방 유래 줄기 세포를 포함하는 지방 조직 세포를 수용하고 농축하도록 구조화된 세포 수집 용기; 및상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포의 무균 수거가 일어나도록 구조화된 출구를 포함하고, 밀폐 시스템을 유지하면서 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 비처리 지방 조직과 혼합하도록 구조화된, 자체 완비형 지방 유래 줄기 세포 처리 장치.
- 제18항에 있어서, 온도 조절 장치를 추가로 포함하는 장치.
- 제19항에 있어서, 상기 온도 조절 장치가 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 냉각하도록 구조화된 것인 장치.
- 제19항에 있어서, 상기 온도 조절 장치가 상기 지방 조직 또는 상기 지방 유래 줄기 세포를 포함하는 농축된 지방 조직 세포를 가열하도록 구조화된 것인 장치.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33885601P | 2001-12-07 | 2001-12-07 | |
US60/338,856 | 2001-12-07 | ||
PCT/US2002/039465 WO2003053346A2 (en) | 2001-12-07 | 2002-12-09 | Systems and methods for treating patients with processed lipoaspirate cells |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020077018245A Division KR100930139B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020107002719A Division KR101150666B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20080103611A true KR20080103611A (ko) | 2008-11-27 |
KR101083454B1 KR101083454B1 (ko) | 2011-11-16 |
Family
ID=23326433
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020077018245A KR100930139B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법 |
KR1020117028207A KR20120003961A (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
KR1020047008785A KR100811995B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법 |
KR1020107002719A KR101150666B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
KR1020087027860A KR101083454B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020077018245A KR100930139B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법 |
KR1020117028207A KR20120003961A (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
KR1020047008785A KR100811995B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법 |
KR1020107002719A KR101150666B1 (ko) | 2001-12-07 | 2002-12-09 | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
Country Status (12)
Country | Link |
---|---|
US (12) | US20030161816A1 (ko) |
EP (4) | EP2308963A3 (ko) |
JP (4) | JP4653952B2 (ko) |
KR (5) | KR100930139B1 (ko) |
CN (2) | CN1630526B (ko) |
AU (1) | AU2002357135C1 (ko) |
BR (1) | BR0214772A (ko) |
CA (2) | CA2849201A1 (ko) |
DK (1) | DK1921133T3 (ko) |
ES (1) | ES2545385T3 (ko) |
HK (1) | HK1078009A1 (ko) |
WO (1) | WO2003053346A2 (ko) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10589268B2 (en) | 2016-06-08 | 2020-03-17 | The Regents Of The University Of California | Method and device for processing tissues and cells |
US10683480B2 (en) | 2013-06-21 | 2020-06-16 | The Regents Of The University Of California | Microfluidic tumor tissue dissociation device and method |
US10722540B1 (en) | 2016-02-01 | 2020-07-28 | The Regents Of The University Of California | Microfluidic device and method for shear stress-induced transformation of cells |
Families Citing this family (346)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8404229B2 (en) | 2001-12-07 | 2013-03-26 | Cytori Therapeutics, Inc. | Methods of using adipose derived stem cells to treat acute tubular necrosis |
CN1630526B (zh) | 2001-12-07 | 2010-05-05 | 马克罗珀尔生物外科公司 | 用加工的脂肪抽吸细胞来治疗患者的系统和方法 |
US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
US9597395B2 (en) | 2001-12-07 | 2017-03-21 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
US20050008626A1 (en) * | 2001-12-07 | 2005-01-13 | Fraser John K. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
US7514075B2 (en) * | 2001-12-07 | 2009-04-07 | Cytori Therapeutics, Inc. | Systems and methods for separating and concentrating adipose derived stem cells from tissue |
US20060204556A1 (en) * | 2001-12-07 | 2006-09-14 | Cytori Therapeutics, Inc. | Cell-loaded prostheses for regenerative intraluminal applications |
US20050048036A1 (en) * | 2001-12-07 | 2005-03-03 | Hedrick Marc H. | Methods of using regenerative cells in the treatment of inherited and acquired disorders of the bone, bone marrow, liver, and other tissues |
US7585670B2 (en) * | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
US7651684B2 (en) | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
US7595043B2 (en) * | 2001-12-07 | 2009-09-29 | Cytori Therapeutics, Inc. | Method for processing and using adipose-derived stem cells |
US20050095228A1 (en) * | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
WO2003080801A2 (en) * | 2002-03-19 | 2003-10-02 | Advanced Research & Technology Transfer | Adipose stromal stem cells for tissue and vascular modification |
US9144583B2 (en) | 2002-03-29 | 2015-09-29 | Tissue Genesis, Inc. | Cell separation apparatus and methods of use |
US8202725B2 (en) | 2004-12-23 | 2012-06-19 | Tissue Genesis Incorporated | Cell sodding method and apparatus |
US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
US7992725B2 (en) * | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
WO2003099412A1 (en) | 2002-05-24 | 2003-12-04 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US7160719B2 (en) * | 2002-06-07 | 2007-01-09 | Mayo Foundation For Medical Education And Research | Bioartificial liver system |
MXPA05009044A (es) * | 2003-02-20 | 2006-03-17 | Macropore Biosurgery Inc | Metodos para utilizar celulas derivadas de tejido adiposo en el tratamiento de condiciones cardiovasculares. |
US8460243B2 (en) | 2003-06-10 | 2013-06-11 | Abbott Diabetes Care Inc. | Glucose measuring module and insulin pump combination |
WO2005011569A2 (en) * | 2003-06-18 | 2005-02-10 | Macropore Biosurgery Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
US20050026275A1 (en) * | 2003-06-23 | 2005-02-03 | Andrej Bahoric | Device, system and method for receiving, processing and dispersing cells |
EP1648999A4 (en) * | 2003-06-25 | 2006-09-06 | Macropore Biosurgery Inc | SYSTEMS AND METHOD FOR SEPARATING AND ENRICHING REGENERATIVE CELLS FROM TISSUE |
US7722536B2 (en) | 2003-07-15 | 2010-05-25 | Abbott Diabetes Care Inc. | Glucose measuring device integrated into a holster for a personal area network device |
US7172579B2 (en) * | 2003-09-09 | 2007-02-06 | Civco Medical Instruments Co., Inc. | System and method for irrigation and tissue evacuation and collection |
EP1670315B1 (en) * | 2003-09-17 | 2017-04-19 | Cytori Therapeutics, Inc. | Methods of using adipose derived regenerative cells in the treatment of peripheral vascular disease |
KR20060036933A (ko) * | 2003-10-07 | 2006-05-02 | 바이오마스터 인코포레이티드 | 지방-유래 전구세포의 세포 분화 |
NZ597965A (en) | 2003-10-08 | 2013-09-27 | Vet Stem Inc | Methods of preparing and using stem cell compositions and kits comprising the same |
ES2602559T3 (es) * | 2004-03-19 | 2017-02-21 | Cytori Therapeutics, Inc. | Soporte celular y dispositivos de contención de soporte celular que contienen células regenerativas |
US7588732B2 (en) * | 2004-03-30 | 2009-09-15 | Genesis Biosystems, Inc. | Autologus tissue harvesting and irrigation device |
US7670596B2 (en) * | 2004-04-23 | 2010-03-02 | Bioe, Inc. | Multi-lineage progenitor cells |
CA2858901C (en) | 2004-06-04 | 2024-01-16 | Carolyn Anderson | Diabetes care host-client architecture and data management system |
KR101197909B1 (ko) | 2004-07-01 | 2012-11-06 | 사이토리 테라퓨틱스, 인크. | 상처 치유를 촉진하기 위해 재생 세포를 사용하는 방법 |
ATE478942T1 (de) * | 2004-07-01 | 2010-09-15 | Cytori Therapeutics Inc | Verfahren zur verwendung regenerativer zellen bei der behandlung von nierenkrankheiten und störungen |
WO2006014158A1 (en) * | 2004-07-01 | 2006-02-09 | Macropore Biosurgery Inc. | Treating disorders by administering regenerative cells. |
JP4937119B2 (ja) * | 2004-07-01 | 2012-05-23 | サイトリ セラピューティクス インコーポレイテッド | 筋骨格疾患の治療に再生細胞を使用する方法 |
CN102204928B (zh) * | 2004-07-01 | 2014-09-17 | 马克罗珀尔生物外科公司 | 再生细胞用于促进伤口愈合的应用 |
WO2006014156A1 (en) * | 2004-07-02 | 2006-02-09 | Macropore Biosurgery, Inc. | Systems and methods for isolating and using clinically safe adipose derived regenerative cells |
US8715733B2 (en) * | 2004-07-23 | 2014-05-06 | DePuy Synthes Products, LLC | Enhanced adipose tissue |
US7993578B2 (en) * | 2004-10-29 | 2011-08-09 | Depuy Spine, Inc. | Methods and kits for aseptic filling of products |
US20060134781A1 (en) * | 2004-12-07 | 2006-06-22 | Bacterin International, Inc. | Three-dimensional cell culture system |
US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
WO2006074075A2 (en) | 2004-12-30 | 2006-07-13 | Primegen Biotech, Llc | Adipose-derived stem cells for tissue regeneration and wound healing |
US20080140451A1 (en) * | 2005-01-10 | 2008-06-12 | Cytori Therapeutics, Inc. | Devices and Methods for Monitoring, Managing, and Servicing Medical Devices |
US7708152B2 (en) | 2005-02-07 | 2010-05-04 | Hanuman Llc | Method and apparatus for preparing platelet rich plasma and concentrates thereof |
US7866485B2 (en) | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
WO2006086199A1 (en) | 2005-02-07 | 2006-08-17 | Hanuman Llc | Platelet rich plasma concentrate apparatus and method |
US9581942B1 (en) | 2005-03-23 | 2017-02-28 | Shippert Enterprises, Llc | Tissue transfer method and apparatus |
US8622997B2 (en) | 2005-03-23 | 2014-01-07 | Ronald D. Shippert | Tissue transfer method and apparatus |
US8062286B2 (en) * | 2005-03-23 | 2011-11-22 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7789872B2 (en) | 2005-03-23 | 2010-09-07 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7794449B2 (en) * | 2005-03-23 | 2010-09-14 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7780649B2 (en) | 2005-03-23 | 2010-08-24 | Shippert Ronald D | Tissue transplantation method and apparatus |
KR100907248B1 (ko) * | 2005-04-21 | 2009-07-10 | (주)안트로젠 | 분화된 어린 지방 세포와 생분해성 중합체의 이식에 의한신체의 부피 대체 방법 |
DE602005026724D1 (de) * | 2005-05-25 | 2011-04-14 | Cytori Therapeutics Inc | Verfahren zur verwendung von aus fettgewebe stammenden zellen bei der behandlung von herz-kreislauf-leiden |
AU2006202209B2 (en) * | 2005-05-27 | 2011-04-14 | Lifescan, Inc. | Amniotic fluid derived cells |
JP2009500297A (ja) * | 2005-06-08 | 2009-01-08 | セントカー・インコーポレーテツド | 眼の変性についての細胞療法 |
JP4907908B2 (ja) * | 2005-06-29 | 2012-04-04 | ルネサスエレクトロニクス株式会社 | 駆動回路及び表示装置 |
EP1902128A4 (en) * | 2005-07-12 | 2009-02-25 | Tissue Genesis Inc | APPARATUS AND METHODS FOR PREPARING TISSUE GRAFT |
US7531355B2 (en) * | 2005-07-29 | 2009-05-12 | The Regents Of The University Of California | Methods and compositions for smooth muscle reconstruction |
FR2890976B1 (fr) * | 2005-09-20 | 2007-12-14 | Univ La Reunion | Kit pour preparer une composition comprenant des cellules adipocytaires et procede d'obtention de ladite composition |
KR20070095494A (ko) * | 2005-09-28 | 2007-10-01 | 세원셀론텍(주) | 지방 조직 수복용 반고형성 젤 조성물의 제조방법 |
US7989205B2 (en) * | 2005-10-06 | 2011-08-02 | American Cryostem Corporation | Cell culture media, kits and methods of use |
JP5117859B2 (ja) | 2005-10-21 | 2013-01-16 | 株式会社カネカ | 幹細胞の分離材および分離方法 |
US20070213717A1 (en) * | 2006-02-14 | 2007-09-13 | Sdgi Holdings, Inc. | Biological fusion in the vertebral column |
US20070213718A1 (en) * | 2006-02-14 | 2007-09-13 | Sdgi Holdings, Inc. | Treatment of the vertebral column |
US20070227547A1 (en) * | 2006-02-14 | 2007-10-04 | Sdgi Holdings, Inc. | Treatment of the vertebral column |
US8163018B2 (en) | 2006-02-14 | 2012-04-24 | Warsaw Orthopedic, Inc. | Treatment of the vertebral column |
US8016859B2 (en) | 2006-02-17 | 2011-09-13 | Medtronic, Inc. | Dynamic treatment system and method of use |
KR100764640B1 (ko) * | 2006-03-08 | 2007-10-10 | 세원셀론텍(주) | 지방조직 수복용 키트 |
US20070224173A1 (en) * | 2006-03-21 | 2007-09-27 | Koullick Edouard A | Nonexpansion Protocol for Autologous Cell-Based Therapies |
US8741643B2 (en) * | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
US20070258956A1 (en) * | 2006-05-02 | 2007-11-08 | Biomet Manufacturing Corp. | Methods and apparatus for promoting hair growth using adipose cell based therapies |
US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US20090304644A1 (en) * | 2006-05-30 | 2009-12-10 | Cytori Therapeutics, Inc. | Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue |
WO2007145442A1 (en) * | 2006-06-14 | 2007-12-21 | Infitron, Inc. | Composition for transplantation comprising adipose stem cells or adipocytes |
JP2009539546A (ja) * | 2006-06-15 | 2009-11-19 | アールエヌエル バイオ カンパニー,リミティッド | ヒト脂肪組織由来成体幹細胞、繊維芽細胞、及び脂肪又は脂肪細胞を含有する皮膚美容又は形成用の組成物 |
WO2008013863A2 (en) * | 2006-07-26 | 2008-01-31 | Cytori Therapeutics, Inc. | Generation of adipose tissue and adipocytes |
US20100092432A1 (en) * | 2006-08-08 | 2010-04-15 | Takenori Ozaki | Cell preparation containing multipotential stem cells originating in fat tissue |
EP2056918B1 (en) * | 2006-08-29 | 2017-08-23 | Tissue Genesis, Inc. | Catheter for cell delivery |
EP1897570A1 (en) * | 2006-09-08 | 2008-03-12 | Gelanus B.V. | Blood recuperation device and method |
CA2872297C (en) | 2006-09-28 | 2016-10-11 | Smith & Nephew, Inc. | Portable wound therapy system |
US8968272B2 (en) * | 2006-10-06 | 2015-03-03 | Lipocosm Llc | Closed system and method for atraumatic, low pressure, continuous harvesting, processing, and grafting of lipoaspirate |
US8241198B2 (en) * | 2006-11-03 | 2012-08-14 | University Of Utah Foundation | Ventricular assist device capable of implantation of stem cells |
US20130324882A1 (en) * | 2012-05-30 | 2013-12-05 | Devicor Medical Products, Inc. | Control for biopsy device |
WO2008099696A1 (ja) * | 2007-02-16 | 2008-08-21 | Olympus Corporation | 脂肪消化終了判定装置および脂肪組織消化装置 |
US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
WO2008124494A1 (en) * | 2007-04-03 | 2008-10-16 | The Cleveland Clinic Foundation | Enrichment of tissue-derived adult stem cells based on retained extracellular matrix material |
US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
WO2008127639A1 (en) | 2007-04-12 | 2008-10-23 | Biomet Biologics, Llc | Buoy suspension fractionation system |
US11174458B2 (en) | 2007-04-23 | 2021-11-16 | Koligo Therapeutics, Inc. | Cell separation apparatus and methods of use |
US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
EP2155860B1 (en) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
EP1997457B1 (en) * | 2007-06-01 | 2010-11-10 | Allergan, Inc. | Biological tissue growth support through induced tensile stress |
US9080145B2 (en) * | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
GB0715259D0 (en) | 2007-08-06 | 2007-09-12 | Smith & Nephew | Canister status determination |
US9408954B2 (en) | 2007-07-02 | 2016-08-09 | Smith & Nephew Plc | Systems and methods for controlling operation of negative pressure wound therapy apparatus |
GB0712763D0 (en) * | 2007-07-02 | 2007-08-08 | Smith & Nephew | Apparatus |
CN101835479A (zh) * | 2007-07-25 | 2010-09-15 | 佰欧益有限公司 | 多系祖细胞分化为软骨细胞 |
RU2473685C2 (ru) | 2007-07-31 | 2013-01-27 | Лайфскен, Инк. | Дифференцировка человеческих эмбриональных стволовых клеток |
RU2473684C2 (ru) * | 2007-11-27 | 2013-01-27 | Лайфскен, Инк. | Дифференцировка человеческих эмбриональных стволовых клеток |
US8309342B2 (en) * | 2007-12-04 | 2012-11-13 | Ingeneron, Inc. | Apparatus and methods for cell isolation |
US11253399B2 (en) | 2007-12-06 | 2022-02-22 | Smith & Nephew Plc | Wound filling apparatuses and methods |
US20130096518A1 (en) | 2007-12-06 | 2013-04-18 | Smith & Nephew Plc | Wound filling apparatuses and methods |
US20090181104A1 (en) * | 2007-12-14 | 2009-07-16 | Gino Rigotti | Breast reconstruction or augmentation using computer-modeled deposition of processed adipose tissue |
US20090192528A1 (en) * | 2008-01-29 | 2009-07-30 | Biomet Biologics, Inc. | Method and device for hernia repair |
US20090209456A1 (en) * | 2008-02-19 | 2009-08-20 | Iliana Sweis | Compositions and methods for improving facial and body aesthetics |
KR102026622B1 (ko) | 2008-02-21 | 2019-09-30 | 얀센 바이오테크 인코포레이티드 | 세포 부착, 배양 및 탈리를 위한 방법, 표면 개질 플레이트 및 조성물 |
GB0803564D0 (en) | 2008-02-27 | 2008-04-02 | Smith & Nephew | Fluid collection |
PL2259774T3 (pl) | 2008-02-27 | 2013-04-30 | Biomet Biologics Llc | Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1 |
WO2009111338A1 (en) | 2008-02-29 | 2009-09-11 | Biomet Manufacturing Corp. | A system and process for separating a material |
ES2665017T3 (es) | 2008-03-20 | 2018-04-24 | University Of Florida Research Foundation, Inc. | Mejorar el potencial de retorno y reparación de células madre en lesiones vasculares |
WO2009120879A1 (en) * | 2008-03-26 | 2009-10-01 | Ams Research Corporation | Treatment of pelvic floor disorders with an adipose-derived cell composition |
CA2722909A1 (en) | 2008-04-30 | 2009-11-05 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
WO2009143241A2 (en) * | 2008-05-21 | 2009-11-26 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to pancreatic cells |
US10912869B2 (en) | 2008-05-21 | 2021-02-09 | Smith & Nephew, Inc. | Wound therapy system with related methods therefor |
US8414519B2 (en) | 2008-05-21 | 2013-04-09 | Covidien Lp | Wound therapy system with portable container apparatus |
US8012077B2 (en) | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
JP5015865B2 (ja) * | 2008-06-09 | 2012-08-29 | オリンパス株式会社 | 脂肪組織洗浄装置 |
WO2009152084A2 (en) * | 2008-06-11 | 2009-12-17 | Cell4Vet Llc | Adipose tissue-derived stem cells for veterinary use |
WO2010002846A1 (en) | 2008-06-30 | 2010-01-07 | Centocor Ortho Biotech Inc. | Differentiation of pluripotent stem cells |
US20100028307A1 (en) * | 2008-07-31 | 2010-02-04 | O'neil John J | Pluripotent stem cell differentiation |
CA2733985C (en) * | 2008-08-14 | 2016-07-12 | Osiris Therapeutics, Inc. | Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions |
WO2010021993A1 (en) * | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
US8827983B2 (en) | 2008-08-21 | 2014-09-09 | Smith & Nephew, Inc. | Sensor with electrical contact protection for use in fluid collection canister and negative pressure wound therapy systems including same |
AU2011247866B9 (en) * | 2008-08-22 | 2014-02-13 | Regeneus Ltd. | Allogeneic therapeutic methods using adipose tissue-derived cell suspensions |
AU2009201915C1 (en) | 2008-08-22 | 2015-02-26 | Regeneus Ltd | Therapeutic methods |
US8512695B2 (en) * | 2008-10-21 | 2013-08-20 | The General Hospital Corporation | Method of preventing fat graft resorption by administering fat-derived cells and poloxamer P 188 |
EP2350265B1 (en) | 2008-10-31 | 2019-04-17 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to the pancreatic endocrine lineage |
CN102272291B (zh) | 2008-10-31 | 2018-01-16 | 詹森生物科技公司 | 人胚胎干细胞向胰腺内分泌谱系的分化 |
US20100112696A1 (en) * | 2008-11-03 | 2010-05-06 | Baxter International Inc. | Apparatus And Methods For Processing Tissue To Release Cells |
US8865199B2 (en) * | 2008-11-17 | 2014-10-21 | Ingeneron, Inc. | Biomatrix composition and methods of biomatrix seeding |
EP2366022B1 (en) * | 2008-11-20 | 2016-04-27 | Janssen Biotech, Inc. | Methods and compositions for cell attachment and cultivation on planar substrates |
US9192695B2 (en) * | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
MX356756B (es) | 2008-11-20 | 2018-06-11 | Centocor Ortho Biotech Inc | Células madre pluripotentes en microportadores. |
US8309343B2 (en) | 2008-12-01 | 2012-11-13 | Baxter International Inc. | Apparatus and method for processing biological material |
JP2010178830A (ja) * | 2009-02-04 | 2010-08-19 | Olympus Corp | 生体移植材とその製造方法 |
DK2408401T3 (en) | 2009-03-03 | 2016-07-18 | Univ Columbia | METHODS, DEVICES AND SYSTEMS FOR KNOGLEVÆGS- ENGINEERING FOR USING A bioreactor |
US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
US10130748B2 (en) * | 2009-03-13 | 2018-11-20 | Mayo Foundation For Medical Education And Research | Bioartificial liver |
US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
AU2009100401A4 (en) * | 2009-04-30 | 2009-06-04 | Gl Holdings Inc Bv | Method of extracting and activating adipose-derived stem cells |
BRPI1009981B1 (pt) | 2009-05-01 | 2019-12-31 | Bimini Tech Llc | sistemas, métodos e composições para otimizar os enxertos enriquecidos de tecido e célula |
US8333740B2 (en) * | 2009-05-01 | 2012-12-18 | Shippert Ronald D | Tissue transfer cannula |
WO2010129775A1 (en) | 2009-05-06 | 2010-11-11 | University Of Virginia Patent Foundation | Self-illuminated handheld lens for retinal examination and photography and related method thereof |
US20100291534A1 (en) * | 2009-05-12 | 2010-11-18 | National Central University | Methods and Systems for Isolating, Ex Vivo Expanding and Harvesting Hematopoietic Stem Cells |
US8100874B1 (en) | 2009-05-22 | 2012-01-24 | Donnell Mark Jordan | Tissue refining device |
US9867788B2 (en) * | 2009-07-09 | 2018-01-16 | Boston Scientific Scimed, Inc. | Multi-chamber cellular mixing and delivery system and method |
US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
RU2540016C2 (ru) | 2009-07-20 | 2015-01-27 | Янссен Байотек, Инк. | Дифференцировка эмбриональных стволовых клеток человека |
KR102058901B1 (ko) | 2009-07-20 | 2019-12-24 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
MX340952B (es) * | 2009-07-20 | 2016-07-29 | Janssen Biotech Inc | Diferenciacion de celulas madre embrionarias humanas. |
US20110213336A1 (en) | 2009-08-05 | 2011-09-01 | Cucin Robert L | Method of and apparatus for sampling, processing and collecting tissue and reinjecting the same into human patients |
US8465471B2 (en) | 2009-08-05 | 2013-06-18 | Rocin Laboratories, Inc. | Endoscopically-guided electro-cauterizing power-assisted fat aspiration system for aspirating visceral fat tissue within the abdomen of a patient |
US8348929B2 (en) | 2009-08-05 | 2013-01-08 | Rocin Laboratories, Inc. | Endoscopically-guided tissue aspiration system for safely removing fat tissue from a patient |
EP2471542B1 (en) * | 2009-08-28 | 2016-04-27 | Osaka Air Machine Service, Ltd. | Therapeutic agent for liver-related diseases |
WO2011041531A1 (en) | 2009-09-30 | 2011-04-07 | Abbott Diabetes Care Inc. | Interconnect for on-body analyte monitoring device |
US20110086426A1 (en) * | 2009-10-13 | 2011-04-14 | Lipostem Corp. | Methods and apparatus for collecting and separating regenerative cells from adipose tissue |
AU2010312537A1 (en) | 2009-10-28 | 2012-05-17 | Genomix Co., Ltd. | Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood |
CN102058905B (zh) * | 2009-11-18 | 2013-04-24 | 四川大学 | 一种复合脂肪颗粒及其制备方法 |
WO2011075700A1 (en) * | 2009-12-18 | 2011-06-23 | Birsect, Llc. | Adipose tissue management systems |
SE0951009A1 (sv) * | 2009-12-22 | 2011-06-23 | Anordning och förfarande för rening och anrikning av biologiskt prov | |
US9150833B2 (en) | 2009-12-23 | 2015-10-06 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
KR101841271B1 (ko) | 2009-12-23 | 2018-03-22 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
AT509071B1 (de) * | 2010-01-29 | 2011-06-15 | Heinrich Karl Georg Ddr | Verfahren zur reinigung mesenchymaler stammzellen |
US10588609B2 (en) * | 2010-02-04 | 2020-03-17 | Procept Biorobotics Corporation | Gene analysis and generation of stem cell methods and apparatus |
JP6013196B2 (ja) * | 2010-03-01 | 2016-10-25 | ヤンセン バイオテツク,インコーポレーテツド | 多能性幹細胞から誘導した細胞を精製するための方法 |
ITGE20100026A1 (it) * | 2010-03-23 | 2011-09-24 | Carlo Tremolada | Metodo e dispositivo per la preparazione di tessuto, in particolare tessuto adiposo per trapianto ottenuto da materiale adiposo lobulare estratto tramite liposuzione |
US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
US8790321B2 (en) * | 2010-04-21 | 2014-07-29 | Genesis Medical Devices, LLC | Apparatus, system, and method for harvesting improved bone graft material with reamer-irrigator-aspirator (RIA) device |
EP2569419B1 (en) | 2010-05-12 | 2019-03-20 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US9296984B2 (en) | 2010-07-09 | 2016-03-29 | The Gid Group, Inc. | Tissue processing apparatus and method for processing adipose tissue |
WO2014039697A1 (en) | 2012-09-06 | 2014-03-13 | The Gid Group, Inc. | Tissue processing apparatus and method for processing adipose tissue |
WO2013106655A1 (en) | 2012-01-11 | 2013-07-18 | The Gid Group, Inc. | Method for processing adipose tissue and processing apparatus |
US9206387B2 (en) | 2010-07-09 | 2015-12-08 | The Gid Group, Inc. | Method and apparatus for processing adipose tissue |
EP2590695A4 (en) | 2010-07-09 | 2017-09-06 | The Gid Group, Inc. | Apparatus and methods relating to collecting and processing human biological material containing adipose |
US9669200B2 (en) | 2010-08-06 | 2017-06-06 | Boston Scientific Scimed, Inc. | Systems and methods for the treatment of pelvic disorders including magnetic particulates |
KR101809301B1 (ko) | 2010-08-06 | 2018-01-18 | 더 제너럴 하스피털 코포레이션 두잉 비즈니스 애즈 매사츄세츠 제너럴 하스피털 | 세포 처리 시스템 및 장치 |
CA2809305C (en) | 2010-08-31 | 2019-06-11 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
SG10201506855RA (en) | 2010-08-31 | 2015-10-29 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
BR112013004514A2 (pt) | 2010-08-31 | 2016-06-07 | Janssen Biotech Inc | diferenciação das células-tronco embrionárias humanas |
US8936766B2 (en) * | 2010-10-04 | 2015-01-20 | Spinesmith Partners, L.P. | Device and method for delivering mechanically released cells from liposuction aspirates |
EP2640827B1 (en) * | 2010-11-16 | 2023-07-19 | Ingeneron, Inc. | Methods for preserving target cells |
US9180172B2 (en) | 2010-12-15 | 2015-11-10 | Ams Research Corporation | Treatment of Peyronies disease |
US8979797B2 (en) | 2010-12-16 | 2015-03-17 | Ams Research Corporation | High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics |
WO2012091911A1 (en) | 2010-12-27 | 2012-07-05 | Intellicell Biosciences, Inc. | Ultrasonic cavitation derived stromal or mesenchymal vascular extracts and cells derived therefrom obtained from adipose tissue and use thereof |
US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
US8887770B1 (en) | 2011-03-17 | 2014-11-18 | Ronald D. Shippert | Vessel fill control method and apparatus |
CN102151153A (zh) * | 2011-03-25 | 2011-08-17 | 吴成翰 | 外科手术过程中组织碎片的回收装置 |
US8512326B2 (en) | 2011-06-24 | 2013-08-20 | Arqos Surgical, Inc. | Tissue extraction devices and methods |
PT3358011T (pt) | 2011-04-26 | 2020-04-23 | Univ Osaka | Péptido para induzir a regeneração de um tecido e a sua utilização |
WO2012148502A2 (en) * | 2011-04-28 | 2012-11-01 | Spinesmith Partners Lp | Lipoaspirate stem cell separation system and methods thereof |
US9109198B2 (en) | 2011-04-29 | 2015-08-18 | General Electric Company | Automated systems and methods for isolating regenerative cells from adipose tissue |
US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
AR087157A1 (es) | 2011-06-20 | 2014-02-26 | Gen Biscuit | Galletita saludable |
US8974448B2 (en) | 2011-06-24 | 2015-03-10 | Iogyn, Inc. | Tissue extraction devices and methods |
US9233193B2 (en) | 2011-06-29 | 2016-01-12 | Iogyn, Inc. | Surgical fluid management systems and methods |
US8582527B2 (en) * | 2011-07-01 | 2013-11-12 | Ofinno Technologies, Llc | Hybrid automatic repeat request in multicarrier systems |
WO2013006379A1 (en) | 2011-07-01 | 2013-01-10 | Dinan Esmael Hejazi | Synchronization signal and control messages in multicarrier ofdm |
US8369280B2 (en) | 2011-07-01 | 2013-02-05 | Ofinno Techologies, LLC | Control channels in multicarrier OFDM transmission |
US9737362B2 (en) | 2011-07-06 | 2017-08-22 | Boston Scientific Scimed, Inc. | Tissue cutting systems and methods |
US11766459B2 (en) | 2011-07-08 | 2023-09-26 | Jointechlabs, Inc. | System and methods for preparation of adipose-derived stem cells |
US10967110B2 (en) | 2011-07-08 | 2021-04-06 | Jointechlabs, Inc. | System and methods for preparation of adipose-derived stem cells |
US9931445B2 (en) | 2011-07-08 | 2018-04-03 | Jointechlabs, Inc. | System and methods for preparation of adipose-derived stem cells |
KR20140070527A (ko) * | 2011-08-29 | 2014-06-10 | 스템퓨틱스 리서치 프라이빗 리미티드 | 지방 조직으로부터의 지방 줄기 세포(svf)의 분리 시스템 및 그 방법 |
US9084847B2 (en) | 2011-09-22 | 2015-07-21 | Iogyn, Inc. | Surgical fluid management systems and methods |
SG2014013676A (en) * | 2011-09-23 | 2014-05-29 | Cell Ideas Pty Ltd | Therapeutics using adipose cells and cell secretions |
US10154664B2 (en) | 2011-10-06 | 2018-12-18 | David K Moscatello | Systems and methods for the digestion of adipose tissue samples obtained from a client for cryopreservation |
JP5628131B2 (ja) * | 2011-10-19 | 2014-11-19 | サイトリ セラピューティクス インコーポレイテッド | 心血管状態の治療において脂肪組織由来細胞を使用する方法 |
US9597149B2 (en) | 2011-11-04 | 2017-03-21 | Iogyn, Inc. | Tissue extraction devices and methods |
PT2775928T (pt) | 2011-11-08 | 2019-05-30 | Auxocell Laboratories Inc | Sistemas e métodos para processar células |
US8446844B1 (en) | 2011-12-04 | 2013-05-21 | Ofinno Technologies, Llc | Handover in multicarrier wireless networks |
US9512405B2 (en) | 2011-12-14 | 2016-12-06 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Non-enzymatic method for isolating human adipose-derived stromal stem cells |
KR102203056B1 (ko) | 2011-12-22 | 2021-01-14 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화 |
US20180028575A1 (en) | 2012-01-30 | 2018-02-01 | Michael Zahalsky | Methods and compositions for treatment of penile defects |
WO2013116327A1 (en) | 2012-01-30 | 2013-08-08 | Zahalsky Michael P | Methods and compositions for treatment of penile defects |
SG11201405110TA (en) * | 2012-02-24 | 2014-11-27 | Masanori Saeki | Cell preparation including fat cell |
WO2013134378A1 (en) | 2012-03-07 | 2013-09-12 | Janssen Biotech, Inc. | Defined media for expansion and maintenance of pluripotent stem cells |
US9497756B2 (en) | 2012-03-25 | 2016-11-15 | Comcast Cable Communications, Llc | Base station radio resource management |
MX359002B (es) | 2012-04-13 | 2018-09-12 | K Stemcell Co Ltd | Metodo y composicion para prevenir la interrupcion y agregacion de celulas madre. |
US9949265B2 (en) | 2012-05-04 | 2018-04-17 | Comcast Cable Communications, Llc | Control channel in a wireless communication system |
WO2013180952A1 (en) | 2012-05-30 | 2013-12-05 | Lifecell Corporation | Device for harvesting, processing, and transferring adipose tissue |
CN108103006A (zh) | 2012-06-08 | 2018-06-01 | 詹森生物科技公司 | 人胚胎干细胞向胰腺内分泌细胞的分化 |
EP2677024B1 (de) | 2012-06-22 | 2019-11-20 | Human Med AG | Vorrichtung zum Separieren von adulten Stammzellen |
ITGE20120084A1 (it) * | 2012-08-24 | 2014-02-25 | Carlo Tremolada | Derivato tissutale di origine non embrionale arricchito di elementi staminali e multipotenti e metodo di preparazione di un medicamento con tale derivato |
US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
JP6288526B2 (ja) * | 2012-08-29 | 2018-03-07 | ユロミ エス.エー. | 脂肪組織を抽出かつ再注入するための装置 |
US20140081237A1 (en) * | 2012-09-20 | 2014-03-20 | Tissue Genesis, Inc. | Hand-held micro-liposuction adipose harvester, processor, and cell concentrator |
CA2868862C (en) | 2012-09-25 | 2017-06-27 | Stem Cell Partners Llc | Method and apparatus for preparing single donor thrombin serum |
CN103842496B (zh) * | 2012-09-28 | 2017-05-17 | 瑞士干细胞基金会 | 制备纯化的干细胞组分的高安全性方法 |
US9498244B2 (en) | 2012-10-19 | 2016-11-22 | Iogyn, Inc. | Medical systems and methods |
RU2649069C2 (ru) | 2012-10-25 | 2018-04-02 | Дженомикс Ко., Лтд. | Новый способ лечения повреждения спинного мозга с применением фрагмента hmgb1 |
AU2013335684B2 (en) | 2012-10-25 | 2017-06-29 | Osaka University | Novel method for treating cardiac infarction using HMGB1 fragment |
US9468709B2 (en) | 2012-11-12 | 2016-10-18 | Shippert Enterprises, Llc | Syringe fill method and apparatus |
KR102030028B1 (ko) * | 2012-11-12 | 2019-10-08 | 한스바이오메드 주식회사 | 지방 조직 농축 시스템 |
EP4039798A1 (en) | 2012-12-31 | 2022-08-10 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells |
RU2658488C2 (ru) | 2012-12-31 | 2018-06-21 | Янссен Байотек, Инк. | Способ получения клеток, экспрессирующих маркеры, характерные для панкреатических эндокринных клеток |
KR101942769B1 (ko) | 2012-12-31 | 2019-01-28 | 얀센 바이오테크 인코포레이티드 | Hb9 조절제를 사용하는 인간 배아 줄기세포의 췌장 내분비 세포로의 분화 |
US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
US9775864B2 (en) | 2013-01-31 | 2017-10-03 | Ams Research Corporation | Vaginal laxity therapy utilizing cell-based bulking compositions |
US9650608B2 (en) | 2013-02-22 | 2017-05-16 | Medivet America, Llc | Activating adipose-derived stem cells for transplantation |
US9867939B2 (en) | 2013-03-12 | 2018-01-16 | Allergan, Inc. | Adipose tissue combinations, devices, and uses thereof |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
KR102312720B1 (ko) | 2013-03-15 | 2021-10-13 | 알로소스 | 연조직 회복 및 재생을 위한 세포 재배치된 콜라겐 매트릭스 |
FR3003576B1 (fr) | 2013-03-25 | 2017-09-01 | Michel Roche | Dispositif et procede de traitement de cellules graisseuses, notamment pour nettoyer et filtrer les cellules graisseuses d’un patient en vue d’un lipofilling |
CN105377159B (zh) | 2013-04-08 | 2018-06-12 | 波士顿科学医学有限公司 | 医疗系统与方法 |
US10124126B2 (en) * | 2013-04-18 | 2018-11-13 | The Regents Of The University Of Colorado, A Body Corporate | System and methods for ventilation through a body cavity |
US9486233B2 (en) | 2013-04-26 | 2016-11-08 | Iogyn, Inc. | Tissue resecting systems and methods |
WO2014178438A1 (ja) * | 2013-05-02 | 2014-11-06 | Saeki Masanori | 毛髪再生用の細胞製剤 |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
KR102580225B1 (ko) | 2013-06-11 | 2023-09-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
ITMO20130227A1 (it) * | 2013-08-02 | 2015-02-03 | Biomed Device Srl | Metodo e sistema per aliquotare grasso da liposuzione |
EP3038629B1 (en) | 2013-09-05 | 2020-11-18 | GID BIO, Inc. | Method for processing adipose tissue |
BR112016005036A2 (pt) | 2013-09-06 | 2020-04-07 | Procept Biorobotics Corp | aparelho para ressecção de tecido guiada por imagem automatizada |
AU2014323629A1 (en) | 2013-09-19 | 2016-05-12 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the modulation of pain and/or fibrosis |
US9248384B2 (en) | 2013-10-02 | 2016-02-02 | Allergan, Inc. | Fat processing system |
US9943639B2 (en) | 2013-10-28 | 2018-04-17 | Boston Scientific Scimed, Inc. | Fluid management system and methods |
BR102013033827B1 (pt) * | 2013-12-27 | 2021-09-08 | Regenera - Medicina Veterinária Avançada Ltda. | Concentrado multipotente e imunocompatível de células-tronco e biofármaco e forma de dosagem que o compreendem |
CA2938268A1 (en) * | 2014-01-31 | 2015-08-06 | Dsm Ip Assets B.V. | Adipose tissue processing centrifuge and methods of use |
BR112016025266A2 (pt) | 2014-05-02 | 2017-08-15 | Lifecell Corp | instrumentos cirúrgicos, e, método de transplante de tecido adiposo |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
US10772997B2 (en) | 2014-05-15 | 2020-09-15 | Ronald D. Shippert | Tissue parcelization method and apparatus |
DK3143127T3 (da) | 2014-05-16 | 2021-09-13 | Janssen Biotech Inc | Anvendelse af små molekyler til at forstærke mafa-ekspression i endokrine pankreasceller |
EP3174569B1 (en) | 2014-07-31 | 2020-01-15 | Smith & Nephew, Inc | Systems and methods for applying reduced pressure therapy |
US9993748B2 (en) | 2014-08-11 | 2018-06-12 | Auxocell Laboratories, Inc. | Centrifuge clip and method |
USD748462S1 (en) | 2014-08-11 | 2016-02-02 | Auxocell Laboratories, Inc. | Centrifuge clip |
CA2959342A1 (en) | 2014-08-25 | 2016-03-03 | Reviticell Holdings, Llc | Modular single-use kits and methods for preparation of biological material |
BR112017004454B1 (pt) * | 2014-09-05 | 2022-11-01 | Procept Biorobotics Corporation | Aparelho para remover células intactas de uma área cirúrgica de um paciente |
TW201627498A (zh) * | 2015-01-26 | 2016-08-01 | 國立中央大學 | 用於純化及培養幹細胞的孔洞結構及其製造方法、幹細胞純化裝置及使用其的幹細胞純化方法、以及幹細胞培養裝置及使用其的幹細胞培養方法 |
BR112017019272A2 (pt) | 2015-03-10 | 2018-05-02 | Allergan Pharmaceuticals Holdings Ireland Unlimited Company | injetor de múltiplas agulhas |
US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
CA2984874A1 (en) * | 2015-05-05 | 2016-11-10 | Samer Srouji | A fat-depleted adipose tissue and a device and method for preparing the same |
US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
CA2986702C (en) | 2015-05-21 | 2023-04-04 | David Wang | Modified demineralized cortical bone fibers |
TWI821751B (zh) * | 2015-06-05 | 2023-11-11 | 瑞士商諾華公司 | 流通式磁性分離/去除卷邊模組及磁性顆粒結合細胞處理方法 |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
WO2017022628A1 (ja) * | 2015-07-31 | 2017-02-09 | 国立大学法人大阪大学 | 上皮疾患に対する治療及び/又は予防有効性を評価する方法、上皮疾患治療剤のスクリーニング方法、及び上皮疾患治療剤 |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
US10188777B2 (en) | 2015-08-20 | 2019-01-29 | Aurastem Llc | Liposuction device and system and use thereof |
AU2016342012A1 (en) | 2015-10-21 | 2018-05-10 | Lifecell Corporation | Systems and methods for medical device control |
MX2018004956A (es) | 2015-10-21 | 2018-09-12 | Lifecell Corp | Sistemas y metodos para control de sondas. |
CN108289915A (zh) * | 2015-11-24 | 2018-07-17 | 日本乐敦制药株式会社 | 包含脂肪组织来源基质细胞的肝病治疗剂及其制造方法 |
CA3008035A1 (en) | 2015-12-22 | 2017-06-29 | Lifecell Corporation | Syringe filling device for fat transfer |
US11139074B2 (en) | 2016-03-14 | 2021-10-05 | Fenwal, Inc. | Cell washing system with process parameter control |
KR101733564B1 (ko) * | 2016-03-15 | 2017-05-10 | 경북대학교병원 | 디케토피페라진을 유효성분으로 포함하는 전신염증질환의 예방 또는 치료용 약학적 조성물 |
ES2964374T3 (es) * | 2016-03-17 | 2024-04-05 | Synova Life Sciences Inc | Aislamiento de células madre del tejido adiposo |
CA3020146A1 (en) | 2016-04-08 | 2017-10-12 | Allergan, Inc. | Aspiration and injection device |
MA45479A (fr) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen |
EP3238759B1 (en) | 2016-04-29 | 2019-07-17 | Fenwal, Inc. | System and method for processing, incubating and/or selecting biological cells |
US10449283B2 (en) | 2016-04-29 | 2019-10-22 | Fenwal, Inc. | System and method for selecting and culturing cells |
CN105955743B (zh) | 2016-04-29 | 2019-08-27 | 腾讯科技(深圳)有限公司 | 资源数值转移请求生成的方法、装置和系统 |
US10702629B2 (en) * | 2016-05-13 | 2020-07-07 | Black Tie Medical Inc. | Conditioning harvested fat for re-injection |
EP3940706A1 (en) | 2016-05-27 | 2022-01-19 | Fenwal, Inc. | Cell processing system and method with preliminary process evaluation |
US10654000B2 (en) | 2016-07-13 | 2020-05-19 | Fenwal, Inc. | Cell processing system and method with centralized data management, monitoring and/or control |
DE102016114043B3 (de) * | 2016-07-29 | 2017-08-10 | Technische Universität Dresden | Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben |
BR112019003871A2 (pt) | 2016-08-30 | 2019-07-16 | Lifecell Corp | sistemas e métodos para controle de dispositivo médico |
EP3535013A4 (en) | 2016-11-02 | 2021-01-20 | The Cooper Health System | METHOD AND APPARATUS FOR DELIVERY OF CELL THERAPIES TO INTIMA, SUBINTIMAL, MEDIA, ADVENTITIAL, PERIADVENTITIAL, OR PERI-VASCULAR TISSUES FROM INSIDE THE LUMP OF THE VAPSELESS LIGHT OF AN ADJACENT BLOOD VESSEL |
US10274495B2 (en) | 2016-12-21 | 2019-04-30 | Fenwal, Inc. | System and method for separating cells incorporating magnetic separation |
US20180207331A1 (en) * | 2017-01-20 | 2018-07-26 | Puregraft Llc | Chamber for the collection of lipoaspirate |
USD851777S1 (en) | 2017-01-30 | 2019-06-18 | Lifecell Corporation | Canister-type device for tissue processing |
EP3607046A4 (en) | 2017-04-07 | 2020-05-27 | Epibone, Inc. | SOWING AND CROP SYSTEM AND METHOD |
WO2018195101A1 (en) | 2017-04-19 | 2018-10-25 | Smith & Nephew, Inc. | Negative pressure wound therapy canisters |
EP3614930A4 (en) | 2017-04-28 | 2020-12-16 | Aurastem LLC | MICRO-LIPO NEEDLE DEVICES AND THEIR USE |
CN111447867B (zh) | 2017-06-06 | 2023-09-22 | 托雷森特股份有限公司 | 用于执行支气管镜检查的设备和系统 |
EP3655518A4 (en) | 2017-07-18 | 2021-07-14 | GID Bio, Inc. | ADAPTIVE TISSUE DIGESTION SYSTEM AND TISSUE PROCESSING PROCEDURES |
US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
GB201720405D0 (en) | 2017-12-07 | 2018-01-24 | Biosafe Sa | A bioprocessing system |
CN111542350B (zh) * | 2018-04-02 | 2022-10-18 | 联合技术实验室公司 | 用于制备脂肪来源干细胞的系统和方法 |
CN108676702B (zh) * | 2018-05-23 | 2021-10-15 | 上海蓓蕊医疗科技有限公司 | 一种提取装置及其操作方法 |
US20210220406A1 (en) | 2018-07-04 | 2021-07-22 | Masanori Saeki | Stem cell filtrate preparation and method for preparing same |
WO2020174005A1 (en) | 2019-02-28 | 2020-09-03 | The Regenerative Group Ltd. | Regenerative combination of plasma and adipose tissue |
US20200325436A1 (en) * | 2019-04-10 | 2020-10-15 | Advanced Solutions Life Sciences, Llc | Systems and Methods For Isolating Microvessels From Adipose Tissue |
US11234684B2 (en) * | 2019-04-19 | 2022-02-01 | Transmed7, Llc | Devices and methods for portable, adjunctive vacuum source and cytology/histology collection systems for biopsy devices |
RU195366U1 (ru) * | 2019-05-08 | 2020-01-23 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр реабилитации и курортологии" Министерства здравоохранения Российской Федерации (ФГБУ НМИЦ РК Минздрава России) | Устройство для выделения из жировой ткани клеток стромально-васкулярной фракции для последующего их применения в регенеративной медицине |
WO2020263858A1 (en) * | 2019-06-24 | 2020-12-30 | The Regents Of The University Of California | Integrated system for mechanical processing of lipoaspirate |
EP3989795A1 (en) | 2019-06-27 | 2022-05-04 | Boston Scientific Scimed, Inc. | Detection of an endoscope to a fluid management system |
EP3770600B1 (en) * | 2019-07-25 | 2023-05-10 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Purification process for cells |
JP2022547024A (ja) | 2019-09-02 | 2022-11-10 | ステムプラント・エルエルシー | 細胞治療の送達のための方法および装置 |
US11272996B2 (en) | 2019-10-04 | 2022-03-15 | Reviticell Holdings, Inc. | Methods and devices for performing sequential procedures utilizing a standardized system |
EP4061531A4 (en) * | 2019-11-22 | 2023-01-11 | Siemens Healthcare Diagnostics, Inc. | APPARATUS, SYSTEMS AND METHODS FOR TRANSFERRING LIQUIDS CONTAINING AGGREGATES |
EP4106778A4 (en) * | 2020-02-18 | 2024-02-28 | Apyx Medical Corp | DEVICES, SYSTEMS AND METHODS FOR DETECTING AND DISTINCTING BETWEEN ADIPOSE TISSUE AND MUSCLE TISSUE DURING MEDICAL PROCEDURES |
GB2587257B (en) * | 2020-03-09 | 2021-09-15 | Alma Lasers Ltd | Lipoaspirate processing |
EP3885444B1 (en) * | 2020-03-27 | 2022-11-09 | Micronbrane Medical Co., Ltd. | A method and device for enriching and detecting microorganisms in a biological sample |
WO2021214162A1 (en) | 2020-04-22 | 2021-10-28 | Cellunite Gmbh | Modular cell processing |
EP4136205A1 (en) | 2020-04-22 | 2023-02-22 | CellUnite GmbH | System and method for automated cell processing |
WO2021220057A2 (en) * | 2020-04-30 | 2021-11-04 | Scicotec Gmbh | Automated integrated liposuction and tissue processing device and method |
CN111557952A (zh) * | 2020-05-28 | 2020-08-21 | 澳门大学 | 间充质干细胞在制备用于促进脂肪移植的制剂中的应用 |
CA3176245A1 (en) * | 2020-09-14 | 2022-03-17 | Ginkgo Bioworks, Inc. | Use of bone morphogenetic proteins and their receptors for aesthetics and cosmetics |
EP4213863A1 (en) * | 2020-09-15 | 2023-07-26 | The Brigham and Women's Hospital, Inc. | In vivo adipose bioreactor and kits for the production and delivery of biologic agents |
AU2022258097A1 (en) | 2021-04-11 | 2023-11-02 | President And Fellows Of Harvard College | Cardiomyocytes and compositions and methods for producing the same |
US11679198B2 (en) | 2021-04-28 | 2023-06-20 | Chopra Gryskiewicz, LLC | System and related methods for fat harvesting |
WO2023001910A1 (en) | 2021-07-23 | 2023-01-26 | Cellunite Gmbh | System and method for cell processing |
CN113976339A (zh) * | 2021-10-25 | 2022-01-28 | 安然 | 改进式脂肪移植装置 |
Family Cites Families (210)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4000275A (en) * | 1969-11-24 | 1976-12-28 | Eli Lilly And Company | Immunosuppressants |
US6436135B1 (en) * | 1974-10-24 | 2002-08-20 | David Goldfarb | Prosthetic vascular graft |
US4346703A (en) | 1979-01-23 | 1982-08-31 | Baxter Travenol Laboratories, Inc. | Solution container for continuous ambulatory peritoneal dialysis |
US4458678A (en) | 1981-10-26 | 1984-07-10 | Massachusetts Institute Of Technology | Cell-seeding procedures involving fibrous lattices |
US4418691A (en) * | 1981-10-26 | 1983-12-06 | Massachusetts Institute Of Technology | Method of promoting the regeneration of tissue at a wound |
IT1212892B (it) | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
JPS5990649A (ja) | 1982-11-12 | 1984-05-25 | Hitachi Koki Co Ltd | 無菌式連続遠心分離システム |
JPS5990649U (ja) | 1982-12-10 | 1984-06-19 | トヨタ自動車株式会社 | オ−トマチツク車の変速位置表示装置 |
US5034135A (en) | 1982-12-13 | 1991-07-23 | William F. McLaughlin | Blood fractionation system and method |
US4699788A (en) | 1984-08-20 | 1987-10-13 | Trustees Of Boston University | Angiogenic factor methods of extraction and method for producing angiogenesis |
JPH022884Y2 (ko) | 1984-12-25 | 1990-01-24 | ||
US5312380A (en) * | 1985-06-06 | 1994-05-17 | Thomas Jefferson University | Endothelial cell procurement and deposition kit |
US5035708A (en) | 1985-06-06 | 1991-07-30 | Thomas Jefferson University | Endothelial cell procurement and deposition kit |
US4820626A (en) | 1985-06-06 | 1989-04-11 | Thomas Jefferson University | Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself |
US5372945A (en) * | 1985-06-06 | 1994-12-13 | Alchas; Paul G. | Device and method for collecting and processing fat tissue and procuring microvessel endothelial cells to produce endothelial cell product |
US4734269A (en) | 1985-06-11 | 1988-03-29 | American Hospital Supply Corporation | Venous reservoir bag with integral high-efficiency bubble removal system |
US5436135A (en) * | 1985-09-02 | 1995-07-25 | Pasteur Merieux Serums Et Vaccins | New preparation of placenta collagen, their extraction method and their applications |
WO1987002812A1 (en) | 1985-10-25 | 1987-05-07 | Yianni Attikiouzel | Warning system for rear end vehicle collisions |
US4990333A (en) | 1985-12-20 | 1991-02-05 | Angio Medical Corporation | Method for healing bone damage |
ES2004281A6 (es) | 1986-04-04 | 1988-12-16 | Univ Jefferson | Una superficie protesica implantable para implantacion en un paciente humano |
US4963489A (en) * | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
US5079160A (en) * | 1987-06-08 | 1992-01-07 | Lacy Paul E | Method to isolate clusters of cell subtypes from organs |
US5158867A (en) * | 1987-08-21 | 1992-10-27 | Cryolife Inc. | Method for cryopreserving blood vessels |
US4883755A (en) * | 1987-10-28 | 1989-11-28 | Thomas Jefferson University | Method of reendothelializing vascular linings |
US4834703A (en) | 1987-11-23 | 1989-05-30 | Dubrul Will R | Liposuction filter and lipoplasty device |
JPH01141583A (ja) | 1987-11-27 | 1989-06-02 | Shimadzu Corp | 細胞処理チャンバ |
US5143063A (en) * | 1988-02-09 | 1992-09-01 | Fellner Donald G | Method of removing adipose tissue from the body |
JP2564611B2 (ja) | 1988-06-13 | 1996-12-18 | 株式会社日立製作所 | 生物細胞用遠心分離装置及び細胞の分離方法 |
US4897185A (en) * | 1988-10-06 | 1990-01-30 | Cobe Laboratories, Inc. | Cell processing apparatus and method |
US5092883A (en) * | 1988-12-28 | 1992-03-03 | Eppley Barry L | Method for promoting soft connective tissue growth and repair in mammals |
US5087244A (en) | 1989-01-31 | 1992-02-11 | C. R. Bard, Inc. | Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen |
JPH0666B2 (ja) | 1989-05-02 | 1994-01-05 | 倉敷紡績株式会社 | Dnaの単離精製法 |
US5521087A (en) | 1989-05-10 | 1996-05-28 | Massachusetts Institute Of Technology | Method for producing oriented connective tissue cells in a ligament configuration |
EP0418979A3 (en) | 1989-09-21 | 1992-03-04 | Michele Dr. Zocchi | Method and apparatus for producing human autologous collagen |
DE69018246T2 (de) | 1990-02-09 | 1995-11-02 | Univ Jefferson | Vorrichtung zur Sammlung und Verarbeitung von fetten Geweben zur Herstellung von Endothel-Zellprodukt. |
EP0448770A1 (en) | 1990-03-28 | 1991-10-02 | Katsuya Takasu | Method for separating collagen |
US5641622A (en) | 1990-09-13 | 1997-06-24 | Baxter International Inc. | Continuous centrifugation process for the separation of biological components from heterogeneous cell populations |
JPH0675497B2 (ja) | 1990-11-15 | 1994-09-28 | 倉敷紡績株式会社 | プラスミド分離装置 |
US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US5837539A (en) * | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US6010696A (en) * | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
US6197325B1 (en) * | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US5234608A (en) | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
JP2637297B2 (ja) | 1991-02-22 | 1997-08-06 | 帝人株式会社 | 遠心分離装置 |
NZ242533A (en) | 1991-05-03 | 1995-05-26 | Becton Dickinson Co | Device for collecting and processing fat tissue; vessel with rinsing and digesting chamber, drain chamber and isolation chamber |
JPH0611309B2 (ja) | 1991-05-28 | 1994-02-16 | 克弥 高須 | コラーゲン採取装置 |
US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
US5261612A (en) * | 1991-10-09 | 1993-11-16 | Newman-Ftaiha, Inc. | Method and apparatus for extracting injectable collagen from adipose tissue |
WO1993007824A1 (en) | 1991-10-18 | 1993-04-29 | Baxter International Inc. | Bone marrow kit |
US5549674A (en) * | 1992-03-02 | 1996-08-27 | The Regents Of The University Of Michigan | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo |
AU665813B2 (en) | 1992-05-11 | 1996-01-18 | Sulzer Medizinaltechnik Ag | Process and apparatus for producing endoprostheses |
WO1994000484A1 (en) * | 1992-06-22 | 1994-01-06 | Young Henry E | Scar inhibitory factor and use thereof |
AU4678993A (en) | 1992-07-16 | 1994-02-14 | Board Of Trustees Of The Leland Stanford Junior University | Methods for using dendritic cells to activate t cells |
US5336178A (en) | 1992-11-02 | 1994-08-09 | Localmed, Inc. | Intravascular catheter with infusion array |
US5654186A (en) * | 1993-02-26 | 1997-08-05 | The Picower Institute For Medical Research | Blood-borne mesenchymal cells |
US5328459A (en) * | 1993-05-06 | 1994-07-12 | Laghi Aldo A | Apparatus and method for dispensing and aspirating high viscosity materials |
JP3331398B2 (ja) * | 1993-05-28 | 2002-10-07 | バクスター、インターナショナル、インコーポレイテッド | 不均質な細胞混合物から特定の細胞集団を分離するための方法、装置およびシステム |
US5316942A (en) * | 1993-06-16 | 1994-05-31 | Battelle Memorial Institute | Process for the production of low-cost soluble high-molecular weight collagen |
US5409833A (en) | 1993-07-01 | 1995-04-25 | Baxter International Inc. | Microvessel cell isolation apparatus |
US5591625A (en) * | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
US5470307A (en) * | 1994-03-16 | 1995-11-28 | Lindall; Arnold W. | Catheter system for controllably releasing a therapeutic agent at a remote tissue site |
JPH07255469A (ja) | 1994-03-17 | 1995-10-09 | Kurabo Ind Ltd | 動物細胞の凍結保存液 |
US5599335A (en) | 1994-03-29 | 1997-02-04 | The Procter & Gamble Company | Absorbent members for body fluids having good wet integrity and relatively high concentrations of hydrogel-forming absorbent polymer |
US5811050A (en) * | 1994-06-06 | 1998-09-22 | Gabower; John F. | Electromagnetic interference shield for electronic devices |
US6017719A (en) | 1994-06-14 | 2000-01-25 | Nexell Therapeutics, Inc. | Positive and positive/negative cell selection mediated by peptide release |
EP0955951B1 (en) * | 1994-07-01 | 2005-08-24 | Edwards Lifesciences Corporation | Device for harvesting adipose tissue containing autologous microvascular endothelial cells |
EP0717630A1 (de) | 1994-07-08 | 1996-06-26 | SULZER Medizinaltechnik AG | Verfahren zur herstellung von implantationsmaterialien |
FR2723315B1 (fr) * | 1994-08-02 | 1996-10-25 | Cird Galderma | Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes |
DE4439480C1 (de) | 1994-11-08 | 1996-06-05 | Asta Medica Ag | Verwendung von D,L- alpha-Liponsäure und/oder ihren Enantiomeren, und/oder ihren Derivaten als Zusatz bei Erythrozyten-Flüssigkonserven für homologe und autologe Erythrozyten-Konzentrate und als Zusatz bei Erythrozyten-Kryokonserven für homologe und autologe Erythrozytenkonzentrate |
US5688531A (en) * | 1994-12-23 | 1997-11-18 | Ramot University Authority For Applied Research And Industrial Development, Ltd. | Method for regulating bone forming cells |
US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
US5906934A (en) * | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
US5888409A (en) * | 1995-06-07 | 1999-03-30 | Cedars-Sinai Medical Center | Methods for cell isolation and collection |
US5783408A (en) * | 1995-06-07 | 1998-07-21 | Hamilton; Bradford S. | Method for screening potential anti-obesity agents |
US6238908B1 (en) | 1995-06-07 | 2001-05-29 | Aastrom Biosciences, Inc. | Apparatus and method for maintaining and growth biological cells |
US5653689A (en) | 1995-09-30 | 1997-08-05 | Abacus Design & Development, Inc. | Infusion catheter |
EP0868505B1 (en) * | 1995-11-16 | 2005-02-02 | Case Western Reserve University | In vitro chondrogenic induction of human mesenchymal stem cells |
JP2000503542A (ja) | 1996-01-16 | 2000-03-28 | デピュイ オーソピーディック,インコーポレイテッド | 造血及び非造血組織からの前駆細胞の分離及び in vivo 骨及び軟骨再生におけるそれらの使用 |
US6200606B1 (en) * | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
US6206873B1 (en) * | 1996-02-13 | 2001-03-27 | El. En. S.P.A. | Device and method for eliminating adipose layers by means of laser energy |
JP4609807B2 (ja) | 1996-03-28 | 2011-01-12 | 雪印乳業株式会社 | 骨強化用医薬、飲食品及び飼料 |
JP3322595B2 (ja) * | 1996-03-28 | 2002-09-09 | テルモ株式会社 | フィルター装置および生体微細組織の分離・回収方法 |
US5830714A (en) | 1996-04-17 | 1998-11-03 | Molecular Biology Resources, Inc. | Biologically active fragment of bacillus stearothermophilus DNA polymerase |
AU2730497A (en) | 1996-04-17 | 1997-11-07 | Case Western Reserve University | Cryopreservation and extensive subculturing of human mesenchymal stem cells |
WO1997040137A1 (en) | 1996-04-19 | 1997-10-30 | Osiris Therapeutics, Inc. | Regeneration and augmentation of bone using mesenchymal stem cells |
JP2000508922A (ja) | 1996-04-26 | 2000-07-18 | ケース ウエスターン リザーブ ユニバーシティ | 間葉幹細胞を用いる皮膚再生 |
US6020196A (en) * | 1996-05-09 | 2000-02-01 | Baxter International Inc. | Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells |
US5785965A (en) | 1996-05-15 | 1998-07-28 | The Board Of Trustees Of The Leland Stanford Junior Univ. | VEGF gene transfer into endothelial cells for vascular prosthesis |
US5869037A (en) * | 1996-06-26 | 1999-02-09 | Cornell Research Foundation, Inc. | Adenoviral-mediated gene transfer to adipocytes |
JPH1017310A (ja) | 1996-07-03 | 1998-01-20 | Ehime Pref Gov | コラーゲン、ヒドロキシアパタイトの製造方法及びその生成物 |
US5727740A (en) * | 1996-07-03 | 1998-03-17 | Robinson; Forrest L. | Method and apparatus for recovering fractional components of soil |
US6368356B1 (en) * | 1996-07-11 | 2002-04-09 | Scimed Life Systems, Inc. | Medical devices comprising hydrogel polymers having improved mechanical properties |
US5837444A (en) * | 1996-07-16 | 1998-11-17 | Shah; Kumarpal A. | Islet cell transplantation machine for diabetes cure |
US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
US5919234A (en) | 1996-08-19 | 1999-07-06 | Macropore, Inc. | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
US5980887A (en) * | 1996-11-08 | 1999-11-09 | St. Elizabeth's Medical Center Of Boston | Methods for enhancing angiogenesis with endothelial progenitor cells |
EP0941027A4 (en) | 1996-11-15 | 2000-08-09 | Osiris Therapeutics Inc | MSC megakaryocyte precursor composition and method for isolating MSCS associated with isolated megakaryocytes by isolating megakaryocytes |
EP0941311B1 (de) | 1996-11-19 | 2004-07-28 | Boehringer Mannheim Gmbh | Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden |
US5728740A (en) * | 1996-12-05 | 1998-03-17 | Barrett; Mark William | Method and composition for treating bacterial infections in plants |
ATE306811T1 (de) | 1996-12-06 | 2005-11-15 | Osiris Therapeutics Inc | Verbesserte chondrogene differenzierung von menschlichen mesenchym-stammzellen |
US5830741A (en) * | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
AU731766B2 (en) * | 1997-01-24 | 2001-04-05 | Asahi Kasei Medical Co., Ltd. | Cell separation method |
AU6165598A (en) | 1997-02-18 | 1998-09-08 | Lxr Biotechnology Inc. | Bak promotor expression system |
US7767452B2 (en) * | 1997-02-20 | 2010-08-03 | Kleinsek Don A | Tissue treatments with adipocyte cells |
US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
EP0989855A4 (en) | 1997-05-13 | 2002-06-12 | Osiris Therapeutics Inc | REGENERATION OF CARTILAGE IN OSTEOARTHRITIS BY MEANS OF HUMAN MESENCHYMAL STEM CELLS |
WO1998052629A2 (en) | 1997-05-20 | 1998-11-26 | Zymequest, Inc. | Cell processing systems |
US5786207A (en) | 1997-05-28 | 1998-07-28 | University Of Pittsburgh | Tissue dissociating system and method |
US5817050A (en) * | 1997-05-29 | 1998-10-06 | Klein; Jeffrey A. | Liposuction cannula |
US6451207B1 (en) | 1997-06-04 | 2002-09-17 | Dexter Magnetic Technologies, Inc. | Magnetic cell separation device |
JPH114682A (ja) | 1997-06-16 | 1999-01-12 | Asahi Medical Co Ltd | 有核細胞保存方法、有核細胞保存用組成物及び有核細胞分離方法 |
AU8476698A (en) * | 1997-07-03 | 1999-01-25 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells from peripheral blood |
CA2296704C (en) * | 1997-07-14 | 2010-10-19 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
JPH1157731A (ja) | 1997-08-15 | 1999-03-02 | Japan Organo Co Ltd | 浄水処理方法および浄水処理設備 |
EP1003847A4 (en) | 1997-09-04 | 2005-04-06 | Science Res Lab Inc | SEPARATION OF CELLS BY USE OF ELECTRIC FIELDS |
US6077987A (en) | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
US6269716B1 (en) | 1998-11-18 | 2001-08-07 | Macropore, Inc. | High-torque resorbable screws |
AU1615599A (en) | 1997-12-02 | 1999-06-16 | Zen Bio, Inc. | Differentiation of adipose stromal cells into osteoblasts and uses thereof |
US6251295B1 (en) | 1998-01-08 | 2001-06-26 | Nexell Therapeutics Inc. | Method for recirculation washing of blood cells |
AU749358B2 (en) | 1998-01-23 | 2002-06-27 | Pall Corporation | Biological fluid treatment system |
AU749675B2 (en) | 1998-03-13 | 2002-07-04 | Mesoblast International Sarl | Uses for human non-autologous mesenchymal stem cells |
US6206914B1 (en) * | 1998-04-30 | 2001-03-27 | Medtronic, Inc. | Implantable system with drug-eluting cells for on-demand local drug delivery |
CA2329519A1 (en) | 1998-06-08 | 1999-12-16 | Osiris Therapeutics, Inc. | In vitro maintenance of hematopoietic stem cells |
US6001642A (en) | 1998-06-29 | 1999-12-14 | Wyle Laboratories, Inc. Life Sciences | Bioreactor and cell culturing processes using the bioreactor |
DE19841835C2 (de) | 1998-09-12 | 2003-05-28 | Fresenius Ag | Zentrifugenkammer für einen Zellseparator |
AU767241B2 (en) * | 1998-09-14 | 2003-11-06 | Qiang Xu | Immunosuppressive agents |
US6184035B1 (en) * | 1998-11-18 | 2001-02-06 | California Institute Of Technology | Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells |
US6090121A (en) * | 1998-12-02 | 2000-07-18 | Weber; Paul J. | Highly flexible, reinforced swan neck liposuction cannulas |
US20030082152A1 (en) | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
US6777231B1 (en) * | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
KR100968164B1 (ko) * | 1999-03-10 | 2010-07-06 | 더 리전츠 오브 더 유니버시티 오브 캘리포니아 | 지방 유래 간세포 및 격자 |
JP4195250B2 (ja) | 1999-03-12 | 2008-12-10 | 株式会社神鋼環境ソリューション | ビール等の発酵食品類の製造方法 |
JP4014350B2 (ja) | 1999-03-12 | 2007-11-28 | 株式会社神鋼環境ソリューション | 酵母液貯留用攪拌槽と、その攪拌槽を用いたビール等の発酵食品類の製造方法、並びにその攪拌槽に具備された攪拌翼 |
US6764820B2 (en) | 1999-03-26 | 2004-07-20 | Ludwig Institute For Cancer Research | Screening for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3) |
US20030211085A1 (en) * | 2000-03-16 | 2003-11-13 | Sanberg Paul R. | Cell therapy for chronic stroke |
US6316247B1 (en) | 1999-06-15 | 2001-11-13 | University Of Pittsburgh | System and method for refining liposuctioned adipose tissue |
US6804558B2 (en) * | 1999-07-07 | 2004-10-12 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
US6555374B1 (en) | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
US6429013B1 (en) | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
CN1134537C (zh) * | 1999-09-08 | 2004-01-14 | 何清华 | 人原始间叶干细胞群的制备方法 |
EP1218489B1 (en) | 1999-09-24 | 2009-03-18 | Cybios LLC | Pluripotent embryonic-like stem cells, compositions, methods and uses thereof |
US20030161817A1 (en) * | 2001-03-28 | 2003-08-28 | Young Henry E. | Pluripotent embryonic-like stem cells, compositions, methods and uses thereof |
JP3524835B2 (ja) | 2000-02-25 | 2004-05-10 | 財団法人地球環境産業技術研究機構 | 光合成培養装置及び培養方法 |
PT1261694E (pt) | 2000-02-26 | 2008-04-03 | Artecel Inc | Células estaminais pluripotentes produzidas a partir de células estromais derivadas de tecido adiposo e suas utilizações. |
US20070111935A1 (en) | 2000-04-06 | 2007-05-17 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs |
AU5743601A (en) * | 2000-04-28 | 2001-11-12 | Childrens Medical Center | Isolation of mesenchymal stem cells and use thereof |
AU2001264565B2 (en) | 2000-05-03 | 2006-12-07 | Vegenics Limited | A method for activating only the vascular endothelial growth factor receptor-3 and uses thereof |
WO2001088103A2 (en) * | 2000-05-12 | 2001-11-22 | University Of Utah Research Foundation | Compositions and methods for tissue dedifferentiation and regeneration |
US20040172283A1 (en) | 2003-02-09 | 2004-09-02 | Vanderveen Timothy W. | Medication management and event logger and analysis system |
US7094874B2 (en) | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
CA2422852C (en) * | 2000-09-18 | 2012-06-26 | Organogenesis Inc. | Methods for treating a patient using a bioengineered flat sheet graft prostheses |
JP4141122B2 (ja) * | 2000-11-06 | 2008-08-27 | サカセ・アドテック株式会社 | インフレータブル構造及びインフレータブル構造を備えたアレーアンテナ及びインフレータブル構造の展開方法 |
US6576464B2 (en) * | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
US7192445B2 (en) * | 2000-12-06 | 2007-03-20 | Astra Tech Ab | Medical prosthetic devices and implants having improved biocompatibility |
US6517526B1 (en) | 2000-12-29 | 2003-02-11 | Yehuda Tamari | Container for lyophilizing biological products |
FR2819265B1 (fr) | 2001-01-10 | 2004-01-02 | Centre Nat Rech Scient | Cellules du tissu adipeux extramedullaire et leurs applications dans la reconstitution des lignees hematopoietiques |
JP2005501802A (ja) | 2001-01-23 | 2005-01-20 | ボストン サイエンティフィック コーポレイション | 虚血心筋を処置するための限局性心筋注入方法 |
US6723131B2 (en) | 2001-02-28 | 2004-04-20 | The Cleveland Clinic Foundation | Composite bone marrow graft material with method and kit |
JP2004532202A (ja) | 2001-03-15 | 2004-10-21 | シアオ,ヨング−フー | 生存哺乳動物における臨床的に認められた形態の心臓の病状を治療的に処置する方法 |
JP2004536794A (ja) | 2001-04-09 | 2004-12-09 | メドトロニック、インコーポレイテッド | マイクロ遠心機を用いる血液成分の分離方法及びその使用法 |
US6623959B2 (en) * | 2001-06-13 | 2003-09-23 | Ethicon, Inc. | Devices and methods for cell harvesting |
WO2003001329A2 (en) | 2001-06-20 | 2003-01-03 | Power Medical Interventions, Inc. | A method and system for integrated medical tracking |
WO2003002165A1 (en) * | 2001-06-28 | 2003-01-09 | Cook Biotech Incorporated | Graft prosthesis devices containing renal capsule collagen |
US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
CN100516200C (zh) | 2001-11-09 | 2009-07-22 | 阿特塞尔科学公司 | 用于角膜和眶内缺损修复的脂肪组织来源的基质细胞及其应用 |
US20030152558A1 (en) * | 2001-11-09 | 2003-08-14 | Christopher Luft | Methods and compositions for the use of stromal cells to support embryonic and adult stem cells |
US6833270B2 (en) * | 2001-11-27 | 2004-12-21 | Biorep Technologies, Inc. | Apparatus and method for isolating cells from organs |
US8404229B2 (en) | 2001-12-07 | 2013-03-26 | Cytori Therapeutics, Inc. | Methods of using adipose derived stem cells to treat acute tubular necrosis |
US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
US20050008626A1 (en) | 2001-12-07 | 2005-01-13 | Fraser John K. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
CN1630526B (zh) * | 2001-12-07 | 2010-05-05 | 马克罗珀尔生物外科公司 | 用加工的脂肪抽吸细胞来治疗患者的系统和方法 |
US7595043B2 (en) | 2001-12-07 | 2009-09-29 | Cytori Therapeutics, Inc. | Method for processing and using adipose-derived stem cells |
US7514075B2 (en) * | 2001-12-07 | 2009-04-07 | Cytori Therapeutics, Inc. | Systems and methods for separating and concentrating adipose derived stem cells from tissue |
US7651684B2 (en) | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
US7585670B2 (en) | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
CA2470031A1 (en) | 2001-12-20 | 2003-07-03 | Macropore, Inc. | Systems and methods for treating patients with collagen-rich material extracted from adipose tissue |
US20030161916A1 (en) | 2002-02-26 | 2003-08-28 | Roy Parker | Method for preparing food article |
JP2005531507A (ja) | 2002-03-02 | 2005-10-20 | ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | ストローマ細胞前駆体による抗癌物質の局所的な産生および/または送達方法 |
JP2005536186A (ja) | 2002-03-07 | 2005-12-02 | ルードビッヒ、インスティテュート、フォー、キャンサー、リサーチ | リンパ管および血管内皮細胞遺伝子 |
WO2003080801A2 (en) | 2002-03-19 | 2003-10-02 | Advanced Research & Technology Transfer | Adipose stromal stem cells for tissue and vascular modification |
WO2004013275A2 (fr) | 2002-07-31 | 2004-02-12 | Yves Saint-Laurent Parfums | Cellules souches issues de tissu adipeux et cellules differenciees issues de ces cellules |
US20050271636A1 (en) | 2002-08-09 | 2005-12-08 | St. Jude Children's Research Hospital, Inc. | Diagnostic and therapeutic uses for prox 1 |
JP2004099471A (ja) | 2002-09-05 | 2004-04-02 | Cardio Corp | 心筋梗塞および心不全の治療薬 |
US20040136968A1 (en) | 2002-09-27 | 2004-07-15 | Verigen Ag | Autologous cells on a support matrix for tissue repair |
WO2004052418A1 (ja) | 2002-12-06 | 2004-06-24 | National Institute Of Advanced Industrial Science And Technology | 骨−軟骨組織の再生用移植体 |
MXPA05009044A (es) | 2003-02-20 | 2006-03-17 | Macropore Biosurgery Inc | Metodos para utilizar celulas derivadas de tejido adiposo en el tratamiento de condiciones cardiovasculares. |
JP2004272762A (ja) | 2003-03-11 | 2004-09-30 | Topcon Corp | 医療用ネットワークシステム、情報処理装置、課金処理方法、そのためのプログラム、および、このプログラムを記録した情報記録媒体 |
US20040193274A1 (en) | 2003-03-28 | 2004-09-30 | Trieu Hai H. | Materials and methods for augmenting and/or repairing intervertebral discs |
US20040197304A1 (en) | 2003-04-01 | 2004-10-07 | The Procter & Gamble Company And Alimentary Health, Ltd. | Methods of determining efficacy of treatments of inflammatory diseases of the bowel |
EP1620024B1 (en) | 2003-05-07 | 2007-04-04 | Aleeva Medical, Inc. | Device for treating back pain by re-establishing the exchange of nutrient and waste |
EP1648999A4 (en) | 2003-06-25 | 2006-09-06 | Macropore Biosurgery Inc | SYSTEMS AND METHOD FOR SEPARATING AND ENRICHING REGENERATIVE CELLS FROM TISSUE |
FR2859381B1 (fr) | 2003-09-05 | 2008-07-25 | Centre Nat Rech Scient | Utilisaton de cellules issues du tissu adipeux pour induire la formation d'un reseau vasculaire fonctionnel |
EP1670315B1 (en) | 2003-09-17 | 2017-04-19 | Cytori Therapeutics, Inc. | Methods of using adipose derived regenerative cells in the treatment of peripheral vascular disease |
KR20060036933A (ko) | 2003-10-07 | 2006-05-02 | 바이오마스터 인코포레이티드 | 지방-유래 전구세포의 세포 분화 |
NZ597965A (en) | 2003-10-08 | 2013-09-27 | Vet Stem Inc | Methods of preparing and using stem cell compositions and kits comprising the same |
EP1692275B1 (en) | 2003-11-04 | 2010-12-29 | Biomaster, Inc. | Method and system for preparing stem cells from fat tissue |
DE602004024125D1 (de) | 2003-12-25 | 2009-12-24 | Kanazawa University Technology | Induktion einer myokardzelle unter verwendung einer säuger-knochenmarkzelle oder aus nabelschnurblut stammenden zelle und fettgewebe |
WO2005087954A2 (en) | 2004-03-08 | 2005-09-22 | Ludwig Institute For Cancer Research | Roles of foxc2, pdgfr, vegfr3 in lymphatic vessel development |
WO2006014156A1 (en) | 2004-07-02 | 2006-02-09 | Macropore Biosurgery, Inc. | Systems and methods for isolating and using clinically safe adipose derived regenerative cells |
WO2006028648A2 (en) | 2004-08-13 | 2006-03-16 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Support system for flexible lyophilization containers |
EP2428563A1 (en) | 2005-02-10 | 2012-03-14 | Regents Of The University Of Minnesota | Vascular/lymphatic endothelial cells |
DE602005026724D1 (de) | 2005-05-25 | 2011-04-14 | Cytori Therapeutics Inc | Verfahren zur verwendung von aus fettgewebe stammenden zellen bei der behandlung von herz-kreislauf-leiden |
US7780635B2 (en) | 2006-02-09 | 2010-08-24 | Aderans Research Institute, Inc. | Apparatus and methods for delivering fluid and material to a subject |
FR2901136B1 (fr) | 2006-05-18 | 2010-10-01 | Centre Nat Rech Scient | Utilisation de cellules derivees du tissu adipeux pour la preparation d'un medicament anti-tumoral |
WO2008013863A2 (en) | 2006-07-26 | 2008-01-31 | Cytori Therapeutics, Inc. | Generation of adipose tissue and adipocytes |
WO2009076548A1 (en) | 2007-12-13 | 2009-06-18 | Cytori Therapeutics, Inc. | Methods of inhibiting tumor development using adipose-derived regenerative cells |
WO2010124235A1 (en) | 2009-04-23 | 2010-10-28 | Cytori Therapeutics, Inc. | Use adipose tissue-derived regenerative cells in the modulation of inflammation in the pancreas and in the kidney |
-
2002
- 2002-12-09 CN CN028279689A patent/CN1630526B/zh not_active Expired - Lifetime
- 2002-12-09 KR KR1020077018245A patent/KR100930139B1/ko active IP Right Grant
- 2002-12-09 WO PCT/US2002/039465 patent/WO2003053346A2/en active Application Filing
- 2002-12-09 US US10/316,127 patent/US20030161816A1/en not_active Abandoned
- 2002-12-09 DK DK07124088.1T patent/DK1921133T3/en active
- 2002-12-09 CA CA2849201A patent/CA2849201A1/en not_active Abandoned
- 2002-12-09 JP JP2003554106A patent/JP4653952B2/ja not_active Expired - Lifetime
- 2002-12-09 EP EP20100183737 patent/EP2308963A3/en not_active Withdrawn
- 2002-12-09 EP EP20100183690 patent/EP2305276A3/en not_active Withdrawn
- 2002-12-09 CN CN201010105630.7A patent/CN101897724B/zh not_active Expired - Lifetime
- 2002-12-09 EP EP20070124088 patent/EP1921133B1/en not_active Expired - Lifetime
- 2002-12-09 ES ES07124088.1T patent/ES2545385T3/es not_active Expired - Lifetime
- 2002-12-09 CA CA2469370A patent/CA2469370C/en not_active Expired - Fee Related
- 2002-12-09 KR KR1020117028207A patent/KR20120003961A/ko not_active Application Discontinuation
- 2002-12-09 KR KR1020047008785A patent/KR100811995B1/ko active IP Right Grant
- 2002-12-09 KR KR1020107002719A patent/KR101150666B1/ko active IP Right Grant
- 2002-12-09 KR KR1020087027860A patent/KR101083454B1/ko active IP Right Grant
- 2002-12-09 BR BRPI0214772-6A patent/BR0214772A/pt not_active Application Discontinuation
- 2002-12-09 AU AU2002357135A patent/AU2002357135C1/en not_active Ceased
- 2002-12-09 EP EP02805565.5A patent/EP1572071B1/en not_active Expired - Lifetime
-
2003
- 2003-07-07 US US10/614,392 patent/US7501115B2/en active Active
- 2003-07-07 US US10/614,644 patent/US7390484B2/en active Active
- 2003-07-07 US US10/614,431 patent/US7473420B2/en not_active Expired - Fee Related
- 2003-07-07 US US10/614,643 patent/US7429488B2/en not_active Expired - Lifetime
- 2003-07-07 US US10/614,648 patent/US8119121B2/en not_active Expired - Fee Related
-
2005
- 2005-11-09 HK HK05110006.6A patent/HK1078009A1/xx not_active IP Right Cessation
-
2006
- 2006-10-20 US US11/584,202 patent/US7687059B2/en not_active Expired - Fee Related
-
2010
- 2010-01-06 JP JP2010001420A patent/JP5883553B2/ja not_active Expired - Lifetime
- 2010-09-20 US US12/886,341 patent/US7887795B2/en not_active Expired - Fee Related
- 2010-09-20 US US12/886,353 patent/US7901672B2/en not_active Expired - Fee Related
-
2011
- 2011-03-07 US US13/042,334 patent/US8337834B2/en not_active Expired - Fee Related
-
2012
- 2012-04-12 JP JP2012091080A patent/JP5575174B2/ja not_active Expired - Lifetime
- 2012-12-21 US US13/725,814 patent/US9198937B2/en not_active Expired - Fee Related
-
2013
- 2013-11-22 JP JP2013242179A patent/JP5938029B2/ja not_active Expired - Lifetime
-
2015
- 2015-11-30 US US14/954,584 patent/US20160143952A1/en not_active Abandoned
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10683480B2 (en) | 2013-06-21 | 2020-06-16 | The Regents Of The University Of California | Microfluidic tumor tissue dissociation device and method |
US11427798B2 (en) | 2013-06-21 | 2022-08-30 | The Regents Of The University Of California | Microfluidic tissue dissociation device and method |
US10722540B1 (en) | 2016-02-01 | 2020-07-28 | The Regents Of The University Of California | Microfluidic device and method for shear stress-induced transformation of cells |
US10589268B2 (en) | 2016-06-08 | 2020-03-17 | The Regents Of The University Of California | Method and device for processing tissues and cells |
US11130127B2 (en) | 2016-06-08 | 2021-09-28 | The Regents Of The University Of California | Method and device for processing tissues and cells |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101083454B1 (ko) | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A107 | Divisional application of patent | ||
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
AMND | Amendment | ||
E601 | Decision to refuse application | ||
J201 | Request for trial against refusal decision | ||
A107 | Divisional application of patent | ||
AMND | Amendment | ||
B601 | Maintenance of original decision after re-examination before a trial | ||
J301 | Trial decision |
Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20100107 Effective date: 20111007 |
|
S901 | Examination by remand of revocation | ||
GRNO | Decision to grant (after opposition) | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20141023 Year of fee payment: 4 |
|
FPAY | Annual fee payment |
Payment date: 20151016 Year of fee payment: 5 |
|
FPAY | Annual fee payment |
Payment date: 20161019 Year of fee payment: 6 |
|
FPAY | Annual fee payment |
Payment date: 20171018 Year of fee payment: 7 |
|
FPAY | Annual fee payment |
Payment date: 20181018 Year of fee payment: 8 |
|
FPAY | Annual fee payment |
Payment date: 20191016 Year of fee payment: 9 |