BR112013004514A2 - diferenciação das células-tronco embrionárias humanas - Google Patents

diferenciação das células-tronco embrionárias humanas

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Publication number
BR112013004514A2
BR112013004514A2 BR112013004514A BR112013004514A BR112013004514A2 BR 112013004514 A2 BR112013004514 A2 BR 112013004514A2 BR 112013004514 A BR112013004514 A BR 112013004514A BR 112013004514 A BR112013004514 A BR 112013004514A BR 112013004514 A2 BR112013004514 A2 BR 112013004514A2
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BR
Brazil
Prior art keywords
differentiation
stem cells
human embryonic
embryonic stem
cells
Prior art date
Application number
BR112013004514A
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English (en)
Inventor
Alireza Rezania
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of BR112013004514A2 publication Critical patent/BR112013004514A2/pt

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    • C12N5/0602—Vertebrate cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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Abstract

diferenciação das células-tronco embrionárias humanas. a presente invenção refere-se a métodos para promover a diferenciação das células-tronco pluripotentes nas células que produzem insulina. em particular, a presente invenção apresenta um método para produzir uma população de células, em que mais do que 85% das células na população expressam marcadores característicos da linhagem endodérmica definitiva.
BR112013004514A 2010-08-31 2011-08-17 diferenciação das células-tronco embrionárias humanas BR112013004514A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37847210P 2010-08-31 2010-08-31
PCT/US2011/048129 WO2012030539A2 (en) 2010-08-31 2011-08-17 Differentiation of human embryonic stem cells

Publications (1)

Publication Number Publication Date
BR112013004514A2 true BR112013004514A2 (pt) 2016-06-07

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BR112013004514A BR112013004514A2 (pt) 2010-08-31 2011-08-17 diferenciação das células-tronco embrionárias humanas

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US (2) US9528090B2 (pt)
EP (3) EP2853589B1 (pt)
JP (1) JP6218605B2 (pt)
KR (1) KR101836850B1 (pt)
CN (2) CN108517310B (pt)
AR (1) AR082820A1 (pt)
AU (1) AU2011296382B2 (pt)
BR (1) BR112013004514A2 (pt)
CA (1) CA2809303C (pt)
ES (2) ES2659393T3 (pt)
HK (1) HK1243729A1 (pt)
MX (1) MX355077B (pt)
PL (2) PL2611910T3 (pt)
RU (1) RU2627168C2 (pt)
SG (2) SG10201506852VA (pt)
WO (1) WO2012030539A2 (pt)

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