DOP2013000240A - Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga - Google Patents

Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga

Info

Publication number
DOP2013000240A
DOP2013000240A DO2013000240A DO2013000240A DOP2013000240A DO P2013000240 A DOP2013000240 A DO P2013000240A DO 2013000240 A DO2013000240 A DO 2013000240A DO 2013000240 A DO2013000240 A DO 2013000240A DO P2013000240 A DOP2013000240 A DO P2013000240A
Authority
DO
Dominican Republic
Prior art keywords
methods
compositions
mitocondrial
automotive
energy transfer
Prior art date
Application number
DO2013000240A
Other languages
English (en)
Inventor
Jonathan Lee Tilly
Dori C Woods
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47010014&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2013000240(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of DOP2013000240A publication Critical patent/DOP2013000240A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer

Abstract

Se describen composiciones derivadas de células madre ovogoniales (OSC), tales como mitocondrias con citoplasma libre de núcleo o aisladas, y usos de las composiciones derivadas de OSC en procedimientos que aumentan la fertilidad autóloga. CIP.C12N 5/075
DO2013000240A 2011-04-14 2013-10-14 Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga DOP2013000240A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161475561P 2011-04-14 2011-04-14
US201261600505P 2012-02-17 2012-02-17

Publications (1)

Publication Number Publication Date
DOP2013000240A true DOP2013000240A (es) 2014-06-30

Family

ID=47010014

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2013000240A DOP2013000240A (es) 2011-04-14 2013-10-14 Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga

Country Status (24)

Country Link
US (5) US8647869B2 (es)
EP (3) EP3498826A1 (es)
JP (3) JP5793237B2 (es)
CN (2) CN106350479A (es)
AP (1) AP2013007229A0 (es)
AU (1) AU2012242591B2 (es)
BR (1) BR112013026501A2 (es)
CA (2) CA2868239C (es)
CL (1) CL2013002989A1 (es)
CO (1) CO6862102A2 (es)
CR (1) CR20130592A (es)
DO (1) DOP2013000240A (es)
EA (1) EA201391523A1 (es)
GT (1) GT201300248A (es)
HK (1) HK1202890A1 (es)
IL (3) IL228829A (es)
MA (1) MA35105B1 (es)
MX (1) MX2013011990A (es)
NI (1) NI201300108A (es)
NZ (1) NZ706806A (es)
PE (1) PE20141517A1 (es)
SG (2) SG194448A1 (es)
WO (1) WO2012142500A2 (es)
ZA (2) ZA201308494B (es)

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AU2012276038B2 (en) 2011-06-29 2017-08-31 President And Fellows Of Harvard College Compositions and methods for enhancing bioenergetic status in female germ cells
CN103146644B (zh) * 2013-02-27 2014-09-24 青岛农业大学 一种小鼠毛囊干细胞体外向原始生殖细胞分化的技术方法
CN103969232A (zh) * 2014-04-03 2014-08-06 浙江大学 一种三色荧光标记筛选抗阿霉素肾毒性活性物质的方法
CN106573985A (zh) 2014-09-16 2017-04-19 Ova科学股份有限公司 抗vasa抗体及其生产方法和用途
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EP3362566A4 (en) * 2015-10-16 2019-03-20 CooperSurgical, Inc. QUANTIFICATION OF MITOCHONDRIAL DNA AND METHODS FOR DETERMINING THE QUALITY OF AN EMBRYO
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US20190177687A1 (en) * 2016-06-23 2019-06-13 Tithon Biotech Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
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CN106190963A (zh) * 2016-07-13 2016-12-07 浙江大学 一种采用线粒体移植促进损伤神经元存活的方法
WO2019060297A1 (en) * 2017-09-19 2019-03-28 Unity Biotechnology, Inc. MITOCHONDRIAL REJUVENATION AS A TREATMENT FOR AGE-RELATED AND NEURODEGENERATIVE CONDITIONS
CN108004200A (zh) * 2017-12-01 2018-05-08 佳学基因医学技术（北京）有限公司 一种线粒体转移液及其制备方法
CN111621555A (zh) * 2019-06-13 2020-09-04 中国科学院广州生物医药与健康研究院 生物标志物及其应用
US20230011622A1 (en) * 2020-02-20 2023-01-12 Northeastern University Methods and compositions for use of mitochondrial therapies to improve female reproductive potential
CN114134106B (zh) * 2021-11-26 2024-01-26 北京大学人民医院 一种尿源间充质干细胞线粒体及其移植方法与应用

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Also Published As

Publication number Publication date
US20190300850A1 (en) 2019-10-03
WO2012142500A2 (en) 2012-10-18
US20130052727A1 (en) 2013-02-28
JP2014514928A (ja) 2014-06-26
EP3498826A1 (en) 2019-06-19
EP2787073A1 (en) 2014-10-08
JP2018007659A (ja) 2018-01-18
SG10201406171QA (en) 2014-10-30
PE20141517A1 (es) 2014-10-25
NI201300108A (es) 2014-08-26
SG194448A1 (en) 2013-12-30
CA2832336A1 (en) 2012-10-18
JP5793237B2 (ja) 2015-10-14
CA2868239A1 (en) 2012-10-18
CO6862102A2 (es) 2014-02-10
BR112013026501A2 (pt) 2016-11-29
CN103562378A (zh) 2014-02-05
EA201391523A1 (ru) 2014-03-31
AU2012242591B2 (en) 2014-10-23
HK1202890A1 (en) 2015-10-09
IL247447B (en) 2018-10-31
MA35105B1 (fr) 2014-05-02
JP2016019532A (ja) 2016-02-04
MX2013011990A (es) 2013-11-20
CR20130592A (es) 2014-03-05
WO2012142500A3 (en) 2012-12-13
US9150830B2 (en) 2015-10-06
EP2697365A2 (en) 2014-02-19
NZ617582A (en) 2015-06-26
CA2868239C (en) 2018-07-31
IL228829A0 (en) 2013-12-31
AU2012242591A1 (en) 2013-10-17
ZA201502630B (en) 2016-01-27
US20150353887A1 (en) 2015-12-10
US8647869B2 (en) 2014-02-11
EP2787073B1 (en) 2019-03-20
JP6170103B2 (ja) 2017-07-26
US20130060079A1 (en) 2013-03-07
CN106350479A (zh) 2017-01-25
GT201300248A (es) 2015-09-01
CN103562378B (zh) 2016-09-07
US20120315651A1 (en) 2012-12-13
US8642329B2 (en) 2014-02-04
EP2697365A4 (en) 2014-07-23
ZA201308494B (en) 2016-02-24
NZ706806A (en) 2016-12-23
CL2013002989A1 (es) 2014-05-02
CA2832336C (en) 2016-08-09
IL228829A (en) 2015-02-26
AP2013007229A0 (en) 2013-11-30
IL237089A (en) 2017-05-29

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