CL2015002650A1 - Métodos y composiciones para aumentar la eficacia de la modificación génica, dirigida utilizando reparación génica mediada por oligonucleótidos. - Google Patents

Métodos y composiciones para aumentar la eficacia de la modificación génica, dirigida utilizando reparación génica mediada por oligonucleótidos.

Info

Publication number
CL2015002650A1
CL2015002650A1 CL2015002650A CL2015002650A CL2015002650A1 CL 2015002650 A1 CL2015002650 A1 CL 2015002650A1 CL 2015002650 A CL2015002650 A CL 2015002650A CL 2015002650 A CL2015002650 A CL 2015002650A CL 2015002650 A1 CL2015002650 A1 CL 2015002650A1
Authority
CL
Chile
Prior art keywords
directed
methods
oligonucleotide
compositions
efficiency
Prior art date
Application number
CL2015002650A
Other languages
English (en)
Inventor
Peter R Beetham
Gregory F W Gocal
Christian Schopke
Noel Joy Sauer
James Pearce
Rosa E Segami
Jerry Mozoruk
Original Assignee
Cibus Us Llc
Cibus Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cibus Us Llc, Cibus Europe Bv filed Critical Cibus Us Llc
Publication of CL2015002650A1 publication Critical patent/CL2015002650A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCIÓN PROPORCIONA MEJORES MÉTODOS PARA IA MODIFICACIÓN DE GENES EN CÉLULAS VEGETALES Y PLANTAS Y SEMILLAS DERIVADAS DE ESTAS. MAS ESPECIFICAMENTE, LA INVENCIÓN SE REFIERE A LA MEJORA DE IA EFICACIA DE LA MUTACIÓN GÉNICA DIRIGIDA MEDIANTE LA COMBINACION DE OLIGONUCLEÓTIDOS DE REPARACIÓN GENICA CON ENFOQUES QUE MEJORAN LA DISPONIBILIDAD DE LOS COMPONENTES DE LOS MECANISMOS DE REPARACIÓN GÉNICA DE CÉLULAS DIANA.
CL2015002650A 2013-03-15 2015-09-11 Métodos y composiciones para aumentar la eficacia de la modificación génica, dirigida utilizando reparación génica mediada por oligonucleótidos. CL2015002650A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361801320P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
CL2015002650A1 true CL2015002650A1 (es) 2016-03-28

Family

ID=51538403

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015002650A CL2015002650A1 (es) 2013-03-15 2015-09-11 Métodos y composiciones para aumentar la eficacia de la modificación génica, dirigida utilizando reparación génica mediada por oligonucleótidos.

Country Status (24)

Country Link
US (2) US11434494B2 (es)
EP (1) EP2966984B1 (es)
JP (1) JP2016516408A (es)
KR (1) KR102304487B1 (es)
CN (1) CN105338805A (es)
AU (2) AU2014233465A1 (es)
BR (1) BR112015022848B1 (es)
CA (1) CA2905135C (es)
CL (1) CL2015002650A1 (es)
DK (1) DK2966984T3 (es)
EA (1) EA201591447A1 (es)
ES (1) ES2912400T3 (es)
HK (1) HK1220864A1 (es)
HR (1) HRP20220521T1 (es)
HU (1) HUE058351T2 (es)
IL (1) IL241145B (es)
LT (1) LT2966984T (es)
MY (1) MY191390A (es)
PL (1) PL2966984T3 (es)
PT (1) PT2966984T (es)
RS (1) RS63188B1 (es)
SI (1) SI2966984T1 (es)
UA (1) UA121099C2 (es)
WO (1) WO2014144987A2 (es)

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US11499158B2 (en) 2016-05-13 2022-11-15 Kaneka Corporation Method for modifying plant
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EP3456825A4 (en) 2016-05-13 2020-03-18 Kaneka Corporation METHOD FOR PLANT GENE EDITING
CN106755067A (zh) * 2016-12-05 2017-05-31 天津吉诺沃生物科技有限公司 通过瞬时表达对植物基因进行定点插入的方法及获得的瞬时表达细胞、组织和突变植株
US11859219B1 (en) 2016-12-30 2024-01-02 Flagship Pioneering Innovations V, Inc. Methods of altering a target nucleotide sequence with an RNA-guided nuclease and a single guide RNA

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Also Published As

Publication number Publication date
EA201591447A1 (ru) 2016-05-31
LT2966984T (lt) 2022-05-25
HK1220864A1 (zh) 2017-05-19
SI2966984T1 (sl) 2022-06-30
MY191390A (en) 2022-06-22
AU2014233465A1 (en) 2015-09-03
HUE058351T2 (hu) 2022-07-28
BR112015022848A2 (pt) 2017-11-07
CA2905135A1 (en) 2014-09-18
PL2966984T3 (pl) 2022-06-13
CA2905135C (en) 2022-10-25
DK2966984T3 (da) 2022-04-25
ES2912400T3 (es) 2022-05-25
AU2020220059B2 (en) 2023-06-15
BR112015022848B1 (pt) 2022-10-11
US11434494B2 (en) 2022-09-06
PT2966984T (pt) 2022-05-05
CN105338805A (zh) 2016-02-17
WO2014144987A2 (en) 2014-09-18
EP2966984B1 (en) 2022-03-02
JP2016516408A (ja) 2016-06-09
HRP20220521T1 (hr) 2022-06-10
KR102304487B1 (ko) 2021-09-24
EP2966984A4 (en) 2016-09-21
AU2020220059A1 (en) 2020-09-03
UA121099C2 (uk) 2020-04-10
NZ711146A (en) 2021-08-27
IL241145B (en) 2022-07-01
EP2966984A2 (en) 2016-01-20
US20160304892A1 (en) 2016-10-20
US20230141977A1 (en) 2023-05-11
WO2014144987A3 (en) 2014-12-04
RS63188B1 (sr) 2022-06-30
KR20150132202A (ko) 2015-11-25
IL241145A0 (en) 2015-11-30

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