SI2966984T1 - Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka - Google Patents
Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravkaInfo
- Publication number
- SI2966984T1 SI2966984T1 SI201431952T SI201431952T SI2966984T1 SI 2966984 T1 SI2966984 T1 SI 2966984T1 SI 201431952 T SI201431952 T SI 201431952T SI 201431952 T SI201431952 T SI 201431952T SI 2966984 T1 SI2966984 T1 SI 2966984T1
- Authority
- SI
- Slovenia
- Prior art keywords
- oligonucleotide
- repair
- gene
- modification
- targeted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361801320P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/029621 WO2014144987A2 (en) | 2013-03-15 | 2014-03-14 | Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair |
EP14763072.7A EP2966984B1 (en) | 2013-03-15 | 2014-03-14 | Targeted gene modification using oligonucleotide-mediated gene repair |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2966984T1 true SI2966984T1 (sl) | 2022-06-30 |
Family
ID=51538403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201431952T SI2966984T1 (sl) | 2013-03-15 | 2014-03-14 | Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka |
Country Status (24)
Country | Link |
---|---|
US (2) | US11434494B2 (sl) |
EP (1) | EP2966984B1 (sl) |
JP (1) | JP2016516408A (sl) |
KR (1) | KR102304487B1 (sl) |
CN (1) | CN105338805A (sl) |
AU (2) | AU2014233465A1 (sl) |
BR (1) | BR112015022848B1 (sl) |
CA (1) | CA2905135C (sl) |
CL (1) | CL2015002650A1 (sl) |
DK (1) | DK2966984T3 (sl) |
EA (1) | EA201591447A1 (sl) |
ES (1) | ES2912400T3 (sl) |
HK (1) | HK1220864A1 (sl) |
HR (1) | HRP20220521T1 (sl) |
HU (1) | HUE058351T2 (sl) |
IL (1) | IL241145B (sl) |
LT (1) | LT2966984T (sl) |
MY (1) | MY191390A (sl) |
PL (1) | PL2966984T3 (sl) |
PT (1) | PT2966984T (sl) |
RS (1) | RS63188B1 (sl) |
SI (1) | SI2966984T1 (sl) |
UA (1) | UA121099C2 (sl) |
WO (1) | WO2014144987A2 (sl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11434494B2 (en) | 2013-03-15 | 2022-09-06 | Cibus Us Llc | Targeted gene modification using oligonucleotide-mediated gene repair |
JP2018524992A (ja) * | 2015-07-23 | 2018-09-06 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | ミトコンドリアdnaの編集 |
JP6967217B2 (ja) * | 2016-05-13 | 2021-11-17 | 株式会社カネカ | 形質転換植物の作製方法 |
EP3456825A4 (en) | 2016-05-13 | 2020-03-18 | Kaneka Corporation | METHOD FOR PLANT GENE EDITING |
US11499158B2 (en) | 2016-05-13 | 2022-11-15 | Kaneka Corporation | Method for modifying plant |
CN106755067A (zh) * | 2016-12-05 | 2017-05-31 | 天津吉诺沃生物科技有限公司 | 通过瞬时表达对植物基因进行定点插入的方法及获得的瞬时表达细胞、组织和突变植株 |
US11859219B1 (en) | 2016-12-30 | 2024-01-02 | Flagship Pioneering Innovations V, Inc. | Methods of altering a target nucleotide sequence with an RNA-guided nuclease and a single guide RNA |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
US5024944A (en) | 1986-08-04 | 1991-06-18 | Lubrizol Genetics, Inc. | Transformation, somatic embryogenesis and whole plant regeneration method for Glycine species |
US5008200A (en) | 1988-05-08 | 1991-04-16 | United Agriseeds, Inc. | Propagating multiple whole fertile plants from immature leguminous |
US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
US5550318A (en) | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
DE4216134A1 (de) | 1991-06-20 | 1992-12-24 | Europ Lab Molekularbiolog | Synthetische katalytische oligonukleotidstrukturen |
IT230274Y1 (it) | 1993-06-11 | 1999-06-02 | Silc Spa | Pannolone assorbente sagomato per incontinenza |
DE69425903T2 (de) | 1993-12-09 | 2001-02-15 | Thomas Jefferson University Ph | Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen |
EP0679657B1 (de) | 1994-04-27 | 2003-07-09 | Novartis AG | Nukleoside und Oligonukleotide mit 2'-Ethergruppen |
US5780296A (en) | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
US5760012A (en) | 1996-05-01 | 1998-06-02 | Thomas Jefferson University | Methods and compounds for curing diseases caused by mutations |
US5731181A (en) | 1996-06-17 | 1998-03-24 | Thomas Jefferson University | Chimeric mutational vectors having non-natural nucleotides |
US5888983A (en) | 1996-05-01 | 1999-03-30 | Thomas Jefferson University | Method and oligonucleobase compounds for curing diseases caused by mutations |
US6524613B1 (en) | 1997-04-30 | 2003-02-25 | Regents Of The University Of Minnesota | Hepatocellular chimeraplasty |
AU749410B2 (en) | 1997-04-30 | 2002-06-27 | Regents Of The University Of Minnesota | In vivo use of recombinagenic oligonucleobases to correct genetic lesions in hepatocytes |
WO1999007865A1 (en) | 1997-08-05 | 1999-02-18 | Kimeragen, Inc. | The use of mixed duplex oligonucleotides to effect localized genetic changes in plants |
US6010907A (en) | 1998-05-12 | 2000-01-04 | Kimeragen, Inc. | Eukaryotic use of non-chimeric mutational vectors |
US6004804A (en) | 1998-05-12 | 1999-12-21 | Kimeragen, Inc. | Non-chimeric mutational vectors |
US6271360B1 (en) | 1999-08-27 | 2001-08-07 | Valigen (Us), Inc. | Single-stranded oligodeoxynucleotide mutational vectors |
AR025996A1 (es) | 1999-10-07 | 2002-12-26 | Valigen Us Inc | Plantas no transgenicas resistentes a los herbicidas. |
EP1152058A1 (en) * | 2000-05-03 | 2001-11-07 | Institut Curie | Methods and compositions for effecting homologous recombination |
US20030084473A1 (en) | 2001-08-09 | 2003-05-01 | Valigen | Non-transgenic herbicide resistant plants |
EA026107B1 (ru) | 2007-10-05 | 2017-03-31 | СИБАС ЕУРОП Би.Ви. | СОДЕРЖАЩИЕ МУТАЦИИ ГЕНЫ СИНТАЗЫ АЦЕТОГИДРОКСИКИСЛОТ РАСТЕНИЯ Brassica И ИХ ПРИМЕНЕНИЕ |
US20100291684A1 (en) * | 2007-12-21 | 2010-11-18 | Keygene N.V. | Mutagenesis method using polyethylene glycol mediated introduction of mutagenic nucleobases into plant protoplasts |
CA2720903C (en) * | 2008-04-14 | 2019-01-15 | Sangamo Biosciences, Inc. | Linear donor constructs for targeted integration |
WO2011078662A1 (en) | 2009-12-21 | 2011-06-30 | Keygene N.V. | Dsrna for improved genetic modification of plant dna |
EP2580331A4 (en) * | 2010-06-14 | 2013-11-27 | Univ Iowa State Res Found Inc | NUCLEASE ACTIVITY OF THE TAL EFFECTOR AND FUSION PROTEIN FOKI |
KR20180121665A (ko) * | 2010-07-23 | 2018-11-07 | 시그마-알드리치 컴퍼니., 엘엘씨 | 표적화 엔도뉴클레아제 및 단일-가닥 핵산을 사용하는 게놈 편집 |
WO2012149470A1 (en) | 2011-04-27 | 2012-11-01 | Amyris, Inc. | Methods for genomic modification |
EP2732029B1 (en) * | 2011-07-11 | 2019-01-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for cell reprogramming and genome engineering |
JP6343605B2 (ja) * | 2012-05-25 | 2018-06-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Rna依存性標的dna修飾およびrna依存性転写調節のための方法および組成物 |
US11434494B2 (en) | 2013-03-15 | 2022-09-06 | Cibus Us Llc | Targeted gene modification using oligonucleotide-mediated gene repair |
US9680858B1 (en) | 2013-09-09 | 2017-06-13 | BitSight Technologies, Inc. | Annotation platform for a security risk system |
-
2014
- 2014-03-14 US US14/777,410 patent/US11434494B2/en active Active
- 2014-03-14 MY MYPI2015703120A patent/MY191390A/en unknown
- 2014-03-14 BR BR112015022848-8A patent/BR112015022848B1/pt active IP Right Grant
- 2014-03-14 ES ES14763072T patent/ES2912400T3/es active Active
- 2014-03-14 DK DK14763072.7T patent/DK2966984T3/da active
- 2014-03-14 UA UAA201508559A patent/UA121099C2/uk unknown
- 2014-03-14 SI SI201431952T patent/SI2966984T1/sl unknown
- 2014-03-14 CN CN201480024708.9A patent/CN105338805A/zh active Pending
- 2014-03-14 HU HUE14763072A patent/HUE058351T2/hu unknown
- 2014-03-14 IL IL241145A patent/IL241145B/en unknown
- 2014-03-14 KR KR1020157026632A patent/KR102304487B1/ko active IP Right Grant
- 2014-03-14 HR HRP20220521TT patent/HRP20220521T1/hr unknown
- 2014-03-14 PL PL14763072T patent/PL2966984T3/pl unknown
- 2014-03-14 PT PT147630727T patent/PT2966984T/pt unknown
- 2014-03-14 EA EA201591447A patent/EA201591447A1/ru unknown
- 2014-03-14 CA CA2905135A patent/CA2905135C/en active Active
- 2014-03-14 AU AU2014233465A patent/AU2014233465A1/en not_active Abandoned
- 2014-03-14 RS RS20220373A patent/RS63188B1/sr unknown
- 2014-03-14 JP JP2016503169A patent/JP2016516408A/ja active Pending
- 2014-03-14 EP EP14763072.7A patent/EP2966984B1/en active Active
- 2014-03-14 LT LTEPPCT/US2014/029621T patent/LT2966984T/lt unknown
- 2014-03-14 WO PCT/US2014/029621 patent/WO2014144987A2/en active Application Filing
-
2015
- 2015-09-11 CL CL2015002650A patent/CL2015002650A1/es unknown
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2016
- 2016-07-21 HK HK16108753.2A patent/HK1220864A1/zh unknown
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2020
- 2020-08-17 AU AU2020220059A patent/AU2020220059B2/en active Active
-
2022
- 2022-09-05 US US17/902,970 patent/US20230141977A1/en active Pending
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