SI2966984T1 - Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka - Google Patents

Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka

Info

Publication number
SI2966984T1
SI2966984T1 SI201431952T SI201431952T SI2966984T1 SI 2966984 T1 SI2966984 T1 SI 2966984T1 SI 201431952 T SI201431952 T SI 201431952T SI 201431952 T SI201431952 T SI 201431952T SI 2966984 T1 SI2966984 T1 SI 2966984T1
Authority
SI
Slovenia
Prior art keywords
oligonucleotide
repair
gene
modification
targeted
Prior art date
Application number
SI201431952T
Other languages
English (en)
Inventor
Peter R. Beetham
Gregory F.W. Gocal
Christian Schopke
Noel Joy Sauer
James Pearce
Rosa E. SEGAMI
Jerry Mozoruk
Original Assignee
Cibus Us Llc
Cibus Europe B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cibus Us Llc, Cibus Europe B.V. filed Critical Cibus Us Llc
Publication of SI2966984T1 publication Critical patent/SI2966984T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
SI201431952T 2013-03-15 2014-03-14 Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka SI2966984T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361801320P 2013-03-15 2013-03-15
PCT/US2014/029621 WO2014144987A2 (en) 2013-03-15 2014-03-14 Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair
EP14763072.7A EP2966984B1 (en) 2013-03-15 2014-03-14 Targeted gene modification using oligonucleotide-mediated gene repair

Publications (1)

Publication Number Publication Date
SI2966984T1 true SI2966984T1 (sl) 2022-06-30

Family

ID=51538403

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201431952T SI2966984T1 (sl) 2013-03-15 2014-03-14 Ciljana genska sprememba z oligonukleotidom posredovanega genskega popravka

Country Status (24)

Country Link
US (2) US11434494B2 (sl)
EP (1) EP2966984B1 (sl)
JP (1) JP2016516408A (sl)
KR (1) KR102304487B1 (sl)
CN (1) CN105338805A (sl)
AU (2) AU2014233465A1 (sl)
BR (1) BR112015022848B1 (sl)
CA (1) CA2905135C (sl)
CL (1) CL2015002650A1 (sl)
DK (1) DK2966984T3 (sl)
EA (1) EA201591447A1 (sl)
ES (1) ES2912400T3 (sl)
HK (1) HK1220864A1 (sl)
HR (1) HRP20220521T1 (sl)
HU (1) HUE058351T2 (sl)
IL (1) IL241145B (sl)
LT (1) LT2966984T (sl)
MY (1) MY191390A (sl)
PL (1) PL2966984T3 (sl)
PT (1) PT2966984T (sl)
RS (1) RS63188B1 (sl)
SI (1) SI2966984T1 (sl)
UA (1) UA121099C2 (sl)
WO (1) WO2014144987A2 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11434494B2 (en) 2013-03-15 2022-09-06 Cibus Us Llc Targeted gene modification using oligonucleotide-mediated gene repair
JP2018524992A (ja) * 2015-07-23 2018-09-06 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ ミトコンドリアdnaの編集
JP6967217B2 (ja) * 2016-05-13 2021-11-17 株式会社カネカ 形質転換植物の作製方法
EP3456825A4 (en) 2016-05-13 2020-03-18 Kaneka Corporation METHOD FOR PLANT GENE EDITING
US11499158B2 (en) 2016-05-13 2022-11-15 Kaneka Corporation Method for modifying plant
CN106755067A (zh) * 2016-12-05 2017-05-31 天津吉诺沃生物科技有限公司 通过瞬时表达对植物基因进行定点插入的方法及获得的瞬时表达细胞、组织和突变植株
US11859219B1 (en) 2016-12-30 2024-01-02 Flagship Pioneering Innovations V, Inc. Methods of altering a target nucleotide sequence with an RNA-guided nuclease and a single guide RNA

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5024944A (en) 1986-08-04 1991-06-18 Lubrizol Genetics, Inc. Transformation, somatic embryogenesis and whole plant regeneration method for Glycine species
US5008200A (en) 1988-05-08 1991-04-16 United Agriseeds, Inc. Propagating multiple whole fertile plants from immature leguminous
US5302523A (en) 1989-06-21 1994-04-12 Zeneca Limited Transformation of plant cells
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
DE4216134A1 (de) 1991-06-20 1992-12-24 Europ Lab Molekularbiolog Synthetische katalytische oligonukleotidstrukturen
IT230274Y1 (it) 1993-06-11 1999-06-02 Silc Spa Pannolone assorbente sagomato per incontinenza
DE69425903T2 (de) 1993-12-09 2001-02-15 Thomas Jefferson University Ph Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen
EP0679657B1 (de) 1994-04-27 2003-07-09 Novartis AG Nukleoside und Oligonukleotide mit 2'-Ethergruppen
US5780296A (en) 1995-01-17 1998-07-14 Thomas Jefferson University Compositions and methods to promote homologous recombination in eukaryotic cells and organisms
US5760012A (en) 1996-05-01 1998-06-02 Thomas Jefferson University Methods and compounds for curing diseases caused by mutations
US5731181A (en) 1996-06-17 1998-03-24 Thomas Jefferson University Chimeric mutational vectors having non-natural nucleotides
US5888983A (en) 1996-05-01 1999-03-30 Thomas Jefferson University Method and oligonucleobase compounds for curing diseases caused by mutations
US6524613B1 (en) 1997-04-30 2003-02-25 Regents Of The University Of Minnesota Hepatocellular chimeraplasty
AU749410B2 (en) 1997-04-30 2002-06-27 Regents Of The University Of Minnesota In vivo use of recombinagenic oligonucleobases to correct genetic lesions in hepatocytes
WO1999007865A1 (en) 1997-08-05 1999-02-18 Kimeragen, Inc. The use of mixed duplex oligonucleotides to effect localized genetic changes in plants
US6010907A (en) 1998-05-12 2000-01-04 Kimeragen, Inc. Eukaryotic use of non-chimeric mutational vectors
US6004804A (en) 1998-05-12 1999-12-21 Kimeragen, Inc. Non-chimeric mutational vectors
US6271360B1 (en) 1999-08-27 2001-08-07 Valigen (Us), Inc. Single-stranded oligodeoxynucleotide mutational vectors
AR025996A1 (es) 1999-10-07 2002-12-26 Valigen Us Inc Plantas no transgenicas resistentes a los herbicidas.
EP1152058A1 (en) * 2000-05-03 2001-11-07 Institut Curie Methods and compositions for effecting homologous recombination
US20030084473A1 (en) 2001-08-09 2003-05-01 Valigen Non-transgenic herbicide resistant plants
EA026107B1 (ru) 2007-10-05 2017-03-31 СИБАС ЕУРОП Би.Ви. СОДЕРЖАЩИЕ МУТАЦИИ ГЕНЫ СИНТАЗЫ АЦЕТОГИДРОКСИКИСЛОТ РАСТЕНИЯ Brassica И ИХ ПРИМЕНЕНИЕ
US20100291684A1 (en) * 2007-12-21 2010-11-18 Keygene N.V. Mutagenesis method using polyethylene glycol mediated introduction of mutagenic nucleobases into plant protoplasts
CA2720903C (en) * 2008-04-14 2019-01-15 Sangamo Biosciences, Inc. Linear donor constructs for targeted integration
WO2011078662A1 (en) 2009-12-21 2011-06-30 Keygene N.V. Dsrna for improved genetic modification of plant dna
EP2580331A4 (en) * 2010-06-14 2013-11-27 Univ Iowa State Res Found Inc NUCLEASE ACTIVITY OF THE TAL EFFECTOR AND FUSION PROTEIN FOKI
KR20180121665A (ko) * 2010-07-23 2018-11-07 시그마-알드리치 컴퍼니., 엘엘씨 표적화 엔도뉴클레아제 및 단일-가닥 핵산을 사용하는 게놈 편집
WO2012149470A1 (en) 2011-04-27 2012-11-01 Amyris, Inc. Methods for genomic modification
EP2732029B1 (en) * 2011-07-11 2019-01-16 FUJIFILM Cellular Dynamics, Inc. Methods for cell reprogramming and genome engineering
JP6343605B2 (ja) * 2012-05-25 2018-06-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Rna依存性標的dna修飾およびrna依存性転写調節のための方法および組成物
US11434494B2 (en) 2013-03-15 2022-09-06 Cibus Us Llc Targeted gene modification using oligonucleotide-mediated gene repair
US9680858B1 (en) 2013-09-09 2017-06-13 BitSight Technologies, Inc. Annotation platform for a security risk system

Also Published As

Publication number Publication date
NZ711146A (en) 2021-08-27
UA121099C2 (uk) 2020-04-10
IL241145B (en) 2022-07-01
CA2905135A1 (en) 2014-09-18
LT2966984T (lt) 2022-05-25
PT2966984T (pt) 2022-05-05
BR112015022848A2 (pt) 2017-11-07
US20230141977A1 (en) 2023-05-11
AU2020220059B2 (en) 2023-06-15
EP2966984A4 (en) 2016-09-21
KR102304487B1 (ko) 2021-09-24
EP2966984B1 (en) 2022-03-02
HK1220864A1 (zh) 2017-05-19
AU2020220059A1 (en) 2020-09-03
EA201591447A1 (ru) 2016-05-31
HRP20220521T1 (hr) 2022-06-10
PL2966984T3 (pl) 2022-06-13
IL241145A0 (en) 2015-11-30
DK2966984T3 (da) 2022-04-25
AU2014233465A1 (en) 2015-09-03
US11434494B2 (en) 2022-09-06
WO2014144987A3 (en) 2014-12-04
CL2015002650A1 (es) 2016-03-28
KR20150132202A (ko) 2015-11-25
HUE058351T2 (hu) 2022-07-28
ES2912400T3 (es) 2022-05-25
BR112015022848B1 (pt) 2022-10-11
EP2966984A2 (en) 2016-01-20
CN105338805A (zh) 2016-02-17
RS63188B1 (sr) 2022-06-30
MY191390A (en) 2022-06-22
US20160304892A1 (en) 2016-10-20
CA2905135C (en) 2022-10-25
JP2016516408A (ja) 2016-06-09
WO2014144987A2 (en) 2014-09-18

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