CO7170149A2 - Producción mejorada de derivados de ácidos grasos - Google Patents

Producción mejorada de derivados de ácidos grasos

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Publication number
CO7170149A2
CO7170149A2 CO14240053A CO14240053A CO7170149A2 CO 7170149 A2 CO7170149 A2 CO 7170149A2 CO 14240053 A CO14240053 A CO 14240053A CO 14240053 A CO14240053 A CO 14240053A CO 7170149 A2 CO7170149 A2 CO 7170149A2
Authority
CO
Colombia
Prior art keywords
fatty acid
acid derivatives
improved production
host cells
recombinant host
Prior art date
Application number
CO14240053A
Other languages
English (en)
Inventor
Derek L Greenfield
Andreas W Schirmer
Elizabeth J Clarke
Eli S Groban
Costa Bernardo M Da
Zhihao Hu
Kevin Holden
Noah Helman
Original Assignee
Reg Life Sciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reg Life Sciences Llc filed Critical Reg Life Sciences Llc
Publication of CO7170149A2 publication Critical patent/CO7170149A2/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N9/1025—Acyltransferases (2.3)
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    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
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    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
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    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/0101—Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)(1.3.1.10)
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01039—[Acyl-carrier-protein] S-malonyltransferase (2.3.1.39)
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01041—Beta-ketoacyl-acyl-carrier-protein synthase I (2.3.1.41)
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    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01179—Beta-ketoacyl-acyl-carrier-protein synthase II (2.3.1.179)
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    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0118—Beta-ketoacyl-acyl-carrier-protein synthase III (2.3.1.180)
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    • C12Y402/01—Hydro-lyases (4.2.1)
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    • C12Y503/03—Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
    • C12Y503/03014—Trans-2-decenoyl-[acyl-carrier-protein] isomerase (5.3.3.14)
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    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)

Abstract

la descripción se relaciona con c´leulas anfitrionas recombinantes, que incluyen modificaciones de cepa efectivas para mejorar el titulo, rendimiento y/o productividad de los derivados de ácido graso. la descripción se relaciona adicionalmente con cultivos celulares, que incluyen células anfitrionas recombinantes para la producción fermentativa de derivados de ácidos grasos y composiciones de los mismos
CO14240053A 2012-04-02 2014-10-29 Producción mejorada de derivados de ácidos grasos CO7170149A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261619324P 2012-04-02 2012-04-02

Publications (1)

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CO7170149A2 true CO7170149A2 (es) 2015-01-28

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ID=48087775

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CO14240053A CO7170149A2 (es) 2012-04-02 2014-10-29 Producción mejorada de derivados de ácidos grasos

Country Status (11)

Country Link
US (3) US20150064782A1 (es)
EP (2) EP3674400A1 (es)
JP (3) JP6381518B2 (es)
KR (2) KR102166271B1 (es)
CN (2) CN104395464B (es)
AU (1) AU2013243601B2 (es)
CA (2) CA3162104A1 (es)
CO (1) CO7170149A2 (es)
MX (2) MX366939B (es)
MY (1) MY181688A (es)
WO (1) WO2013152051A2 (es)

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