MX366939B - Producción mejorada de derivados de ácidos grasos. - Google Patents
Producción mejorada de derivados de ácidos grasos.Info
- Publication number
- MX366939B MX366939B MX2014011905A MX2014011905A MX366939B MX 366939 B MX366939 B MX 366939B MX 2014011905 A MX2014011905 A MX 2014011905A MX 2014011905 A MX2014011905 A MX 2014011905A MX 366939 B MX366939 B MX 366939B
- Authority
- MX
- Mexico
- Prior art keywords
- fatty acid
- acid derivatives
- improved production
- host cells
- recombinant host
- Prior art date
Links
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000012262 fermentative production Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/011—3-Oxoacyl-[acyl-carrier-protein] reductase (1.1.1.100)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01009—Enoyl-[acyl-carrier-protein] reductase (NADH) (1.3.1.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/0101—Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)(1.3.1.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01039—[Acyl-carrier-protein] S-malonyltransferase (2.3.1.39)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01041—Beta-ketoacyl-acyl-carrier-protein synthase I (2.3.1.41)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01179—Beta-ketoacyl-acyl-carrier-protein synthase II (2.3.1.179)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/0118—Beta-ketoacyl-acyl-carrier-protein synthase III (2.3.1.180)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/08—Transferases for other substituted phosphate groups (2.7.8)
- C12Y207/08007—Holo-[acyl-carrier-protein] synthase (2.7.8.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01059—3-Hydroxyacyl-[acyl-carrier-protein] dehydratase (4.2.1.59)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/03—Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
- C12Y503/03014—Trans-2-decenoyl-[acyl-carrier-protein] isomerase (5.3.3.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a células hospedadoras recombinantes que incluyen modificaciones de cepas efectivas para mejorar el título, rendimiento y/o productividad de derivados de ácidos grasos. La descripción se refiere adicionalmente a cultivos celulares que incluyen las células hospedadoras recombinantes para la producción fermentativa de derivados de ácidos grasos y composiciones de estos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261619324P | 2012-04-02 | 2012-04-02 | |
PCT/US2013/035037 WO2013152051A2 (en) | 2012-04-02 | 2013-04-02 | Improved production of fatty acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014011905A MX2014011905A (es) | 2015-05-08 |
MX366939B true MX366939B (es) | 2019-07-31 |
Family
ID=48087775
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014011905A MX366939B (es) | 2012-04-02 | 2013-04-02 | Producción mejorada de derivados de ácidos grasos. |
MX2019004568A MX2019004568A (es) | 2012-04-02 | 2014-10-02 | Produccion mejorada de derivados de acidos grasos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019004568A MX2019004568A (es) | 2012-04-02 | 2014-10-02 | Produccion mejorada de derivados de acidos grasos. |
Country Status (12)
Country | Link |
---|---|
US (4) | US20150064782A1 (es) |
EP (2) | EP3674400A1 (es) |
JP (3) | JP6381518B2 (es) |
KR (2) | KR102353113B1 (es) |
CN (2) | CN114456996A (es) |
AU (1) | AU2013243601B2 (es) |
BR (3) | BR122019026142B1 (es) |
CA (2) | CA3162104A1 (es) |
CO (1) | CO7170149A2 (es) |
MX (2) | MX366939B (es) |
MY (1) | MY181688A (es) |
WO (1) | WO2013152051A2 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102353113B1 (ko) | 2012-04-02 | 2022-01-19 | 게노마티카 인코포레이티드 | 지방산 유도체들의 개선된 생산 |
WO2014026162A1 (en) | 2012-08-10 | 2014-02-13 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
MX2015012484A (es) * | 2013-03-15 | 2016-04-20 | Cargill Inc | Mutaciones de acetil-coa carboxilasa. |
US10047383B2 (en) | 2013-03-15 | 2018-08-14 | Cargill, Incorporated | Bioproduction of chemicals |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
EP3022310B1 (en) | 2013-07-19 | 2019-10-16 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
WO2015054138A1 (en) * | 2013-10-10 | 2015-04-16 | William Marsh Rice University | Improved fatty acid productivity |
WO2015095240A2 (en) * | 2013-12-20 | 2015-06-25 | The Regents Of The University Of California | Biosynthesis of 1-undecence and related terminal olefins |
WO2015200335A1 (en) * | 2014-06-23 | 2015-12-30 | Joule Unlimited Technologies, Inc. | Engineered photosynthetic microbes and recombinant synthesis of carbon-based products |
KR20240023194A (ko) | 2014-07-18 | 2024-02-20 | 게노마티카 인코포레이티드 | 지방 디올의 미생물 생산 |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
CN105985987B (zh) * | 2015-03-02 | 2020-01-31 | 苏州安捷生物科技有限公司 | 一种生物法制备脂肪醇的方法 |
CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
JP6934303B2 (ja) | 2017-02-08 | 2021-09-15 | 花王株式会社 | 脂肪族アルコールの生産方法 |
US11339384B2 (en) | 2017-04-03 | 2022-05-24 | Genomatica, Inc. | Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives |
US11512276B2 (en) | 2018-03-30 | 2022-11-29 | Inv Nylon Chemicals Americas, Llc | Methods for controlling oxygen concentration during aerobic biosynthesis |
WO2019191770A1 (en) * | 2018-03-30 | 2019-10-03 | Invista North America S.A.R.L. | Materials and methods for biosynthetic manufacture of pimelic acid and utilization of synthetic polypeptides |
CN112004934B (zh) | 2018-03-30 | 2024-02-23 | 英威达纺织(英国)有限公司 | 用于生物合成制造碳基化学品的材料和方法 |
EP3788057A1 (en) | 2018-05-02 | 2021-03-10 | INVISTA Textiles (U.K.) Limited | Materials and methods for controlling regulation in biosynthesis in species of the genera ralstonia or cupriavidus and organisms related thereto |
EP3788148A1 (en) | 2018-05-02 | 2021-03-10 | INVISTA Textiles (U.K.) Limited | Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-coa-tca balance in species of the genera ralstonia and cupriavidus and organisms related thereto |
EP3788058A1 (en) | 2018-05-02 | 2021-03-10 | INVISTA Textiles (U.K.) Limited | Materials and methods for differential biosynthesis in species of the genera ralstonia and cupriavidus and organisms related thereto |
WO2019213108A1 (en) | 2018-05-02 | 2019-11-07 | Invista Textiles (U.K.) Ltd. | Methods for controlling limitation conditions in product biosynthesis for non-phb generating cupriavidus or ralstonia |
EP3788135A1 (en) | 2018-05-02 | 2021-03-10 | INVISTA Textiles (U.K.) Limited | Materials and methods for controlling oxidation and reduction in biosynthetic pathways of species of the genera ralstonia and cupriavidus and organisms related thereto |
KR102117828B1 (ko) | 2018-07-19 | 2020-06-02 | 서울대학교산학협력단 | 레귤론 변이를 통한 지방산 및 지방산 유도체 생산에서 불포화도 감소 |
WO2020181091A1 (en) | 2019-03-05 | 2020-09-10 | Bp Corporation North America Inc. | Fatty acyl-acp reductases and their uses |
WO2023102629A2 (pt) * | 2021-12-06 | 2023-06-15 | Cnpem - Centro Nacional De Pesquisa Em Energia E Materiais | Enzima quimérica e processo para a produção de alcenos terminais |
CN114634917A (zh) * | 2022-03-25 | 2022-06-17 | 湖南农业大学 | accD突变蛋白在提高植物种子脂肪酸含量中的应用 |
WO2024119298A1 (en) | 2022-12-05 | 2024-06-13 | The Procter & Gamble Company | Fabric and home care composition comprising a polyalkylenecarbonate compound |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
US5028539A (en) | 1988-08-31 | 1991-07-02 | The University Of Florida | Ethanol production using engineered mutant E. coli |
US5424202A (en) | 1988-08-31 | 1995-06-13 | The University Of Florida | Ethanol production by recombinant hosts |
US5482846A (en) | 1988-08-31 | 1996-01-09 | University Of Florida | Ethanol production in Gram-positive microbes |
AU7791991A (en) | 1990-04-24 | 1991-11-11 | Stratagene | Methods for phenotype creation from multiple gene populations |
US5602030A (en) | 1994-03-28 | 1997-02-11 | University Of Florida Research Foundation | Recombinant glucose uptake system |
US6428767B1 (en) | 1995-05-12 | 2002-08-06 | E. I. Du Pont De Nemours And Company | Method for identifying the source of carbon in 1,3-propanediol |
ATE328069T1 (de) * | 1995-10-13 | 2006-06-15 | Harvard College | Phosphopantethenyltransferasen und deren verwendungen |
US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
US5939250A (en) | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
CN1154745C (zh) * | 1999-11-09 | 2004-06-23 | 浙江省农业科学院 | 利用反义基因调控籽粒油脂含量的方法 |
CA2650773C (en) * | 2006-05-19 | 2014-12-02 | Jay D. Keasling | Microorganisms transformed with acetyl-coa carboxylase and wax synthase for production of fatty acid derivatives |
US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
CN101490241A (zh) * | 2006-05-19 | 2009-07-22 | Ls9公司 | 脂肪酸及其衍生物的制备 |
CN101617039A (zh) * | 2006-10-20 | 2009-12-30 | 代表亚利桑那大学的亚利桑那校董会 | 经修饰的蓝细菌 |
US8110093B2 (en) | 2007-03-14 | 2012-02-07 | Ls9, Inc. | Process for producing low molecular weight hydrocarbons from renewable resources |
CA2678915C (en) | 2007-03-28 | 2019-04-09 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
KR101730290B1 (ko) | 2007-05-11 | 2017-04-25 | 토마스 제퍼슨 유니버시티 | 신경변성 질환 및 장애의 치료 및 예방 방법 |
BRPI0813359A2 (pt) | 2007-05-22 | 2014-10-14 | Ls9 Inc | Ácidos nucleicos isolados, vetor, células, métodos para produzir um hidrocarboneto, para produzir uma cetona alifática, para produzir um polipeptídeo purificado, para produzir um hidrocarboneto, para produzir biocombustíveis, hidrocarboneto, biocombustível, polipeptídeo isolado, ácido nucleico isolado, organismos geneticamente engenheirados, método para identificar uma enzima útil para a produção de hidrocarbonetos |
WO2009002480A2 (en) | 2007-06-26 | 2008-12-31 | Danisco Us, Inc., Genencor Division | Acyl transferase having altered substrate specificity |
US7897369B2 (en) | 2007-08-27 | 2011-03-01 | Regents Of The University Of Minnesota | Isoprenoid wax ester synthases, isoprenoid acyl CoA-synthetases, and uses thereof |
TWI351779B (en) | 2007-12-03 | 2011-11-01 | Advance Smart Ind Ltd | Apparatus and method for correcting residual capac |
US8183028B2 (en) | 2007-12-21 | 2012-05-22 | Ls9, Inc. | Methods and compositions for producing olefins |
EP2298880A4 (en) | 2008-03-18 | 2012-02-08 | Kyowa Hakko Kirin Co Ltd | INDUSTRIALLY USEFUL MICROORGANISM |
CN105483068A (zh) | 2008-05-16 | 2016-04-13 | Reg生命科学有限责任公司 | 产生碳氢化合物的方法和组合物 |
JP2012504963A (ja) * | 2008-10-07 | 2012-03-01 | エルエス9・インコーポレイテッド | 脂肪アルデヒドを生産するための方法および組成物 |
CA3041892C (en) | 2008-10-28 | 2022-03-15 | REG Life Sciences, LLC | Methods for producing a fatty alcohol in a host cell |
MX368526B (es) | 2008-12-23 | 2019-10-07 | Reg Life Sciences Llc | Metodos y composiciones relacionados con tioesterasa enzima. |
CA2759273C (en) * | 2009-04-27 | 2018-01-09 | Ls9, Inc. | Production of fatty acid esters |
BRPI1009980A2 (pt) | 2009-05-01 | 2015-08-25 | Univ California | Produtos de ésteres de ácidos graxos a partir de polímeros de biomassa |
US20110162259A1 (en) | 2009-09-25 | 2011-07-07 | Ls9, Inc. | Production of fatty acid derivatives |
US20110151526A1 (en) * | 2009-12-22 | 2011-06-23 | Charles Winston Saunders | Branched-Chain Fatty Acids And Biological Production Thereof |
WO2011100667A1 (en) | 2010-02-14 | 2011-08-18 | Ls9, Inc. | Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols |
WO2012009660A2 (en) * | 2010-07-15 | 2012-01-19 | The Procter & Gamble Company | Detergent compositions comprising microbially produced fatty alcohols and derivatives thereof |
WO2012019175A2 (en) | 2010-08-06 | 2012-02-09 | Mascoma Corporation | Production of malonyl-coa drived products via anaerobic pathways |
CN103842502A (zh) * | 2011-08-03 | 2014-06-04 | Ls9公司 | 制备具有改良的脂肪链长度和饱和度特性的脂肪酸及其衍生物 |
US8790901B2 (en) | 2011-12-14 | 2014-07-29 | Pronutria, Inc. | Microorganisms and methods for producing unsaturated fatty acids |
SI3385374T1 (sl) * | 2012-04-02 | 2020-09-30 | Genomatica, Inc. | Encimi CAR in izboljšana proizvodnja maščobnih alkoholov |
KR102353113B1 (ko) | 2012-04-02 | 2022-01-19 | 게노마티카 인코포레이티드 | 지방산 유도체들의 개선된 생산 |
-
2013
- 2013-04-02 KR KR1020207015194A patent/KR102353113B1/ko active IP Right Grant
- 2013-04-02 US US14/390,378 patent/US20150064782A1/en not_active Abandoned
- 2013-04-02 CN CN202210135822.5A patent/CN114456996A/zh active Pending
- 2013-04-02 EP EP19211601.0A patent/EP3674400A1/en not_active Withdrawn
- 2013-04-02 EP EP13715879.6A patent/EP2834352B1/en active Active
- 2013-04-02 MY MYPI2014002773A patent/MY181688A/en unknown
- 2013-04-02 CA CA3162104A patent/CA3162104A1/en active Pending
- 2013-04-02 JP JP2015504687A patent/JP6381518B2/ja not_active Expired - Fee Related
- 2013-04-02 MX MX2014011905A patent/MX366939B/es active IP Right Grant
- 2013-04-02 BR BR122019026142-3A patent/BR122019026142B1/pt active IP Right Grant
- 2013-04-02 CA CA2883968A patent/CA2883968C/en active Active
- 2013-04-02 BR BR112014024675-0A patent/BR112014024675B1/pt active IP Right Grant
- 2013-04-02 BR BR122019026127-0A patent/BR122019026127B1/pt active IP Right Grant
- 2013-04-02 CN CN201380026304.9A patent/CN104395464B/zh not_active Expired - Fee Related
- 2013-04-02 KR KR1020147030467A patent/KR102166271B1/ko active IP Right Grant
- 2013-04-02 WO PCT/US2013/035037 patent/WO2013152051A2/en active Application Filing
- 2013-04-02 AU AU2013243601A patent/AU2013243601B2/en active Active
-
2014
- 2014-10-02 MX MX2019004568A patent/MX2019004568A/es unknown
- 2014-10-29 CO CO14240053A patent/CO7170149A2/es unknown
-
2017
- 2017-07-14 US US15/650,285 patent/US11060099B2/en active Active
-
2018
- 2018-04-04 JP JP2018072000A patent/JP6738852B2/ja not_active Expired - Fee Related
-
2020
- 2020-05-07 JP JP2020081804A patent/JP7366836B2/ja active Active
-
2021
- 2021-06-01 US US17/335,812 patent/US20210348173A1/en not_active Abandoned
-
2023
- 2023-06-29 US US18/344,219 patent/US20240150774A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2019004568A (es) | Produccion mejorada de derivados de acidos grasos. | |
MX2013005654A (es) | Composiciones y metodos para la produccion de acido 3-hidroxipropionico. | |
IN2015KN00262A (es) | ||
MX2013004353A (es) | Produccion recombinante de n-propanol e isopropanol. | |
MX2019007766A (es) | Variantes de enzima con propiedades de ester sintasa mejoradas. | |
MX343296B (es) | Enzimas de acido carboxilico-reductasa (car) y produccion mejorada de alcoholes grasos. | |
MX357484B (es) | Cepa con deficit de amilasa. | |
MX2014012810A (es) | Sistemas de celulas y metodos para mejorar la sintesis de acidos grasos mediante la expresion de deshidrogenasas. | |
WO2012103261A3 (en) | Compositions and methods for succinate production | |
WO2014093505A3 (en) | Acp-mediated production of fatty acid derivatives | |
MX2016008258A (es) | Celulas eucariotas novedosas y metodos para la expresion recombinante de un producto de interes. | |
EP3030647A4 (en) | Methods of producing algal cell cultures and biomass, lipid compounds and compositions, and related products | |
MX2020001357A (es) | Produccion microbiana de aminas grasas. | |
MY182946A (en) | Production of organic acids by fermentation at low ph | |
PH12014502627A1 (en) | Anti-ageing composition containing dehydrogenated abietic acid as active ingredient | |
WO2012015949A3 (en) | Methods and compositions for improving yields of reduced products of photosynthetic microorganisms | |
EP4282972A3 (en) | Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells | |
WO2012115903A3 (en) | Yeast strain for the production of proteins with modified o-glycosylation | |
SG10201707413SA (en) | Highly Efficient Production Of Lactic Acid From Hemicellulose Sugars By Newly Isolated Thermophilic Bacillus Coagulans Strains | |
IN2014MN01621A (es) | ||
MX2014007760A (es) | Bacterias con unidades transcripcionales reconstruidas y los usos de las mismas. | |
IN2014DN07407A (es) | ||
MX344240B (es) | Mejoramiento a la panificacion con un alto contenido de levadura. | |
MX2020004514A (es) | Variantes mejoradas de acetil-coa carboxilasa. | |
WO2012103263A3 (en) | Compositions and methods for malate and fumarate production |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights |
Owner name: REG LIFE SCIENCES, LLC |
|
FG | Grant or registration |