ATE328069T1 - Phosphopantethenyltransferasen und deren verwendungen - Google Patents
Phosphopantethenyltransferasen und deren verwendungenInfo
- Publication number
- ATE328069T1 ATE328069T1 AT96936313T AT96936313T ATE328069T1 AT E328069 T1 ATE328069 T1 AT E328069T1 AT 96936313 T AT96936313 T AT 96936313T AT 96936313 T AT96936313 T AT 96936313T AT E328069 T1 ATE328069 T1 AT E328069T1
- Authority
- AT
- Austria
- Prior art keywords
- transferases
- phosphopantetheinyl
- phosphopantetheinyl transferases
- vitro
- vivo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1258—Polyribonucleotide nucleotidyltransferase (2.7.7.8), i.e. polynucleotide phosphorylase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US515295P | 1995-10-13 | 1995-10-13 | |
| US2165096P | 1996-07-12 | 1996-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE328069T1 true ATE328069T1 (de) | 2006-06-15 |
Family
ID=26673994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96936313T ATE328069T1 (de) | 1995-10-13 | 1996-10-11 | Phosphopantethenyltransferasen und deren verwendungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6579695B1 (de) |
| EP (1) | EP0861321B1 (de) |
| JP (1) | JP4709333B2 (de) |
| AT (1) | ATE328069T1 (de) |
| AU (1) | AU727348B2 (de) |
| CA (1) | CA2232230C (de) |
| DE (1) | DE69636195T2 (de) |
| WO (1) | WO1997013845A2 (de) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6500960B1 (en) | 1995-07-06 | 2002-12-31 | Stanford University (Board Of Trustees Of The Leland Stanford Junior University) | Method to produce novel polyketides |
| US6066721A (en) * | 1995-07-06 | 2000-05-23 | Stanford University | Method to produce novel polyketides |
| US6558942B1 (en) | 1994-05-06 | 2003-05-06 | The Leland Stanford Junior University | Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold |
| WO1997002358A1 (en) | 1995-07-06 | 1997-01-23 | The Leland Stanford Junior University | Cell-free synthesis of polyketides |
| US6033883A (en) | 1996-12-18 | 2000-03-07 | Kosan Biosciences, Inc. | Production of polyketides in bacteria and yeast |
| US6503741B1 (en) | 1998-05-28 | 2003-01-07 | Kosan Biosciences, Inc. | Polyketide synthase genes from Streptomyces venezuelae |
| US6902913B2 (en) | 1997-04-30 | 2005-06-07 | Kosan Biosciences, Inc. | Recombinant narbonolide polyketide synthase |
| US6117659A (en) | 1997-04-30 | 2000-09-12 | Kosan Biosciences, Inc. | Recombinant narbonolide polyketide synthase |
| CN1188520C (zh) | 1997-07-10 | 2005-02-09 | 高山生物科学股份有限公司 | 在植物中生产聚酮化合物 |
| AU1447700A (en) | 1998-10-28 | 2000-05-15 | Kosan Biosciences, Inc. | Library of novel "unnatural" natural products |
| KR100716272B1 (ko) | 1998-11-20 | 2007-05-09 | 코산 바이오사이언시즈, 인코포레이티드 | 에포틸론 및 에포틸론 유도체의 생산을 위한 재조합 방법 및 물질 |
| US6410301B1 (en) | 1998-11-20 | 2002-06-25 | Kosan Biosciences, Inc. | Myxococcus host cells for the production of epothilones |
| NZ517557A (en) | 1999-10-13 | 2004-05-28 | Univ Leland Stanford Junior | E. coli host cells that synthesize methylmalonyl CoA |
| US6939691B1 (en) * | 1999-10-13 | 2005-09-06 | Board Of Trustees Of The Leland Stanford Junior University | E. coli and Streptomyces host cells that contain MatBC genes or E. coli host cells that contain pcc genes useful for enhanced polyketide production |
| DE60026563D1 (de) | 1999-10-25 | 2006-05-04 | Kosan Biosciences Inc | Herstellung von polyketiden |
| JP2003512073A (ja) | 1999-10-27 | 2003-04-02 | コーサン バイオサイエンシーズ， インコーポレイテッド | ポリケチドの異種産生 |
| US20060035327A1 (en) * | 2001-02-28 | 2006-02-16 | Guangwen Wei | Recombinant super-compound interferon and uses thereof |
| CN1245215C (zh) * | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| US20050079579A1 (en) * | 2001-02-28 | 2005-04-14 | Guangwen Wei | Uses of spatial configuration to modulate protein function |
| AU2003298770A1 (en) * | 2002-12-02 | 2004-06-23 | Biosynexus Inc | Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines |
| EP1627226A1 (de) | 2003-05-23 | 2006-02-22 | Ecole Polytechnique Federale De Lausanne | Auf acylträgerprotein basierendes verfahren zur proteinmarkierung. |
| US7335496B2 (en) * | 2003-06-05 | 2008-02-26 | Ajinomoto Co., Inc. | Method for producing target substance |
| JP2007503812A (ja) * | 2003-08-28 | 2007-03-01 | ヒュイヤンテック（ユーエスエー），インク． | 空間構造によるタンパク質の機能の調節 |
| SI2325202T1 (sl) * | 2003-08-28 | 2015-02-27 | Superlab Far East Limited | Uporabe interferonov s spremenjeno prostorsko strukturo |
| US7585647B2 (en) * | 2003-08-28 | 2009-09-08 | Guangwen Wei | Nucleic acid encoding recombinant interferon |
| KR20060129459A (ko) | 2004-02-13 | 2006-12-15 | 마텍 바이오싸이언스스 코포레이션 | 스키조키트리움 지방산 합성효소 (ｆａｓ) 및 이와 관련된제품 및 방법 |
| WO2006060839A2 (en) * | 2004-12-10 | 2006-06-15 | Universität Für Bodenkultur Wien | Method for identifying ppt inhibitors |
| US20080124302A1 (en) * | 2005-03-09 | 2008-05-29 | Guangwen Wei | Uses of Recombinant Super-Compound Interferons |
| EP1795608A1 (de) * | 2005-12-08 | 2007-06-13 | Centre National de la Recherche Scientifique | Verwendung einer 4' Phosphopantetheinyl-Transferase als Ziel bei Identifizierung antibiotischer Moleküle |
| WO2009092808A1 (en) * | 2008-01-24 | 2009-07-30 | National University Of Ireland, Maynooth | Method for detecting phosphopantetheinyl transferase activity |
| WO2010127186A1 (en) | 2009-04-30 | 2010-11-04 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| EP2432890B1 (de) * | 2009-05-22 | 2015-09-02 | Codexis, Inc. | Industrielle biosynthese von fettalkoholen |
| GB0909743D0 (en) * | 2009-06-05 | 2009-07-22 | F2G Ltd | Antifungal targgt |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| DK2556171T3 (en) | 2010-04-05 | 2015-12-14 | Prognosys Biosciences Inc | Spatially CODED BIOLOGICAL ASSAYS |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| EP3150750B1 (de) | 2011-04-08 | 2018-12-26 | Prognosys Biosciences, Inc. | Peptidkonstrukte und testsysteme dafür |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP3674400A1 (de) * | 2012-04-02 | 2020-07-01 | Genomatica, Inc. | Verbesserte herstellung von fettsäurederivaten |
| ES2703540T3 (es) | 2012-06-04 | 2019-03-11 | Novartis Ag | Métodos de marcación específicos del sitio y moléculas producidas de este modo |
| WO2014043561A1 (en) | 2012-09-14 | 2014-03-20 | The Regents Of The University Of California | Reversible chemoenzymatic labeling of native and fusion carrier protein motifs |
| TW201427681A (zh) | 2013-01-07 | 2014-07-16 | Superlab Far East Ltd | 用空間構象改變的重組干擾素治療腫瘤的方法 |
| EP2972366B1 (de) | 2013-03-15 | 2020-06-17 | Prognosys Biosciences, Inc. | Verfahren zum nachweis von peptid/mhc/tcr-bindung |
| CN111662960B (zh) | 2013-06-25 | 2024-04-12 | 普罗格诺西斯生物科学公司 | 采用微流控装置的空间编码生物分析 |
| WO2015070037A2 (en) | 2013-11-08 | 2015-05-14 | Prognosys Biosciences, Inc. | Polynucleotide conjugates and methods for analyte detection |
| DK3901281T3 (da) | 2015-04-10 | 2023-01-23 | Spatial Transcriptomics Ab | Rumligt adskilt, multipleks nukleinsyreanalyse af biologiske prøver |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| WO2020123320A2 (en) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Imaging system hardware |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| CN110596065B (zh) * | 2019-09-25 | 2021-10-15 | 福建医科大学 | 基于半胱胺-n-乙酰-l-半胱氨酸-金纳米团簇荧光材料的酸性磷酸酶检测方法 |
| EP4025711A2 (de) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Erhöhung der spezifität einer analytbindung |
| WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
| ES2946357T3 (es) | 2019-12-23 | 2023-07-17 | 10X Genomics Inc | Métodos para el análisis espacial usando ligación con molde de ARN |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| EP4242325A3 (de) | 2020-04-22 | 2023-10-04 | 10X Genomics, Inc. | Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau |
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| WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4165207A1 (de) | 2020-06-10 | 2023-04-19 | 10X Genomics, Inc. | Verfahren zur bestimmung einer position eines analyten in einer biologischen probe |
| WO2021263111A1 (en) | 2020-06-25 | 2021-12-30 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| EP4121555A1 (de) | 2020-12-21 | 2023-01-25 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und systeme zur erfassung von sonden und/oder barcodes |
| AU2022238446A1 (en) | 2021-03-18 | 2023-09-07 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993013663A1 (en) * | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| AU665526B2 (en) | 1991-01-17 | 1996-01-11 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| US5824513A (en) | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
-
1996
- 1996-10-11 EP EP96936313A patent/EP0861321B1/de not_active Expired - Lifetime
- 1996-10-11 CA CA002232230A patent/CA2232230C/en not_active Expired - Lifetime
- 1996-10-11 AU AU74357/96A patent/AU727348B2/en not_active Expired
- 1996-10-11 WO PCT/US1996/016202 patent/WO1997013845A2/en active IP Right Grant
- 1996-10-11 AT AT96936313T patent/ATE328069T1/de not_active IP Right Cessation
- 1996-10-11 DE DE69636195T patent/DE69636195T2/de not_active Expired - Lifetime
- 1996-10-11 JP JP51517597A patent/JP4709333B2/ja not_active Expired - Fee Related
- 1996-10-11 US US08/728,742 patent/US6579695B1/en not_active Expired - Lifetime
-
2002
- 2002-09-30 US US10/261,049 patent/US7192735B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030138879A1 (en) | 2003-07-24 |
| JP4709333B2 (ja) | 2011-06-22 |
| AU727348B2 (en) | 2000-12-14 |
| EP0861321B1 (de) | 2006-05-31 |
| DE69636195D1 (de) | 2006-07-06 |
| US6579695B1 (en) | 2003-06-17 |
| CA2232230C (en) | 2005-06-28 |
| DE69636195T2 (de) | 2007-03-29 |
| AU7435796A (en) | 1997-04-30 |
| WO1997013845A2 (en) | 1997-04-17 |
| WO1997013845A3 (en) | 1997-06-26 |
| US7192735B2 (en) | 2007-03-20 |
| EP0861321A2 (de) | 1998-09-02 |
| CA2232230A1 (en) | 1997-04-17 |
| JPH11514868A (ja) | 1999-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |