BR112014015342A8 - células-tronco pluripotentes induzidas de células derivadas do tecido do cordão umbilical humano - Google Patents

células-tronco pluripotentes induzidas de células derivadas do tecido do cordão umbilical humano

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Publication number
BR112014015342A8
BR112014015342A8 BR112014015342A BR112014015342A BR112014015342A8 BR 112014015342 A8 BR112014015342 A8 BR 112014015342A8 BR 112014015342 A BR112014015342 A BR 112014015342A BR 112014015342 A BR112014015342 A BR 112014015342A BR 112014015342 A8 BR112014015342 A8 BR 112014015342A8
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BR
Brazil
Prior art keywords
pluripotent stem
umbilical cord
induced pluripotent
human umbilical
cord tissue
Prior art date
Application number
BR112014015342A
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English (en)
Other versions
BR112014015342A2 (pt
Inventor
Syda Agnieszka
C Kramer Brian
Buensuceso Charito
C Colter David
Dhanaraj Sridevi
Original Assignee
Depuy Synthes Products Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Synthes Products Llc filed Critical Depuy Synthes Products Llc
Publication of BR112014015342A8 publication Critical patent/BR112014015342A8/pt
Publication of BR112014015342A2 publication Critical patent/BR112014015342A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/604—Klf-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/606—Transcription factors c-Myc
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C12N2506/025—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells from extra-embryonic cells, e.g. trophoblast, placenta

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Transplantation (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

resumo patente de invenção: "células-tronco pluripotentes induzidas de células derivadas do tecido do cordão umbilical humano". a presente invenção refere-se a uma célula-tronco pluripotente induzida e ao método de preparação de célula-tronco pluripotente induzida a partir de uma célula derivada de tecido do cordão umbilical humano. mais particularmente, refere-se a uma célula derivada de tecido do cordão umbilical humano ips, que pode ser diferenciada em células de linhagens ectodérmica, mesodérmica e endodérmica.
BR112014015342A 2011-12-20 2012-12-04 células-tronco pluripotentes induzidas de células derivadas do tecido do cordão umbilical humano BR112014015342A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/330,931 US20130157365A1 (en) 2011-12-20 2011-12-20 Induced pluripotent stem cells from human umbilical cord tissue-derived cells
PCT/US2012/067721 WO2013095909A1 (en) 2011-12-20 2012-12-04 Induced pluripotent stem cells from human umbilical cord tissue-derived cells

Publications (2)

Publication Number Publication Date
BR112014015342A8 true BR112014015342A8 (pt) 2017-06-13
BR112014015342A2 BR112014015342A2 (pt) 2017-06-13

Family

ID=47326429

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014015342A BR112014015342A2 (pt) 2011-12-20 2012-12-04 células-tronco pluripotentes induzidas de células derivadas do tecido do cordão umbilical humano

Country Status (14)

Country Link
US (2) US20130157365A1 (pt)
EP (1) EP2794855A1 (pt)
JP (1) JP2015502759A (pt)
KR (1) KR20140113691A (pt)
CN (1) CN104136604A (pt)
AU (1) AU2012355749A1 (pt)
BR (1) BR112014015342A2 (pt)
CA (1) CA2859756A1 (pt)
HK (1) HK1203553A1 (pt)
MX (1) MX2014007473A (pt)
PH (1) PH12014501426A1 (pt)
RU (1) RU2014129756A (pt)
SG (1) SG11201403369XA (pt)
WO (1) WO2013095909A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916339B1 (en) 2013-10-31 2014-12-23 Vivex Biomedical, Inc. Spinal cord tissue dehydrated and micronized
CA2945393C (en) * 2014-04-24 2021-03-23 Board Of Regents, The University Of Texas System Application of induced pluripotent stem cells to generate adoptive cell therapy products
KR101633019B1 (ko) * 2014-07-25 2016-06-23 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도만능 줄기세포주의 제조방법 및 수득된 세포주
US20170307596A1 (en) * 2014-10-15 2017-10-26 Coyne Ip Holdings, Llc Methods for Conducting Stimulus-Response Studies with Induced Pluripotent Stem Cells Derived from Perinatal Cells or Tissues
US9402869B1 (en) 2015-03-27 2016-08-02 Vivex Biomedical, Inc. Treated neural tissue composition
WO2017123312A2 (en) 2015-09-02 2017-07-20 Regeneration Worldwide Company, Inc. Composition and methods of using umbilical cord lining stem cells
CN105624102A (zh) * 2016-02-02 2016-06-01 中国科学院广州生物医药与健康研究院 利用人的尿液细胞构建软骨组织的方法
US11293065B2 (en) 2016-03-14 2022-04-05 Aelan Cell Technologies, Inc. Compositions and methods for the quality control of stem cell preparations
EP3621630A4 (en) 2017-06-14 2021-03-10 The Children's Medical Center HEMATOPOIETIC STEM AND PRECURSOR CELLS FROM HEMOGENIC ENDOTHELIAL CELLS BY EPISOMAL PLASMID GENERAL TRANSFER
US20210095258A1 (en) * 2018-02-22 2021-04-01 Celularity Inc. Post partum tissue-derived induced pluripotent stem cells and uses thereof
CN108714156A (zh) * 2018-05-03 2018-10-30 中国人民解放军军事科学院军事医学研究院 人脐带来源的间充质干细胞培养物或其培养物上清的用途
US20230073449A1 (en) 2020-01-23 2023-03-09 The Children's Medical Center Corporation Stroma-free t cell differentiation from human pluripotent stem cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703121B2 (en) 2003-06-27 2014-04-22 DePuy Synthes Products, LLC Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
WO2007016245A2 (en) * 2005-07-29 2007-02-08 Vivicells International, Llc Reprogramming of adult or neonic stem cells and methods of use
US20110014164A1 (en) * 2008-02-15 2011-01-20 President And Fellows Of Harvard College Efficient induction of pluripotent stem cells using small molecule compounds
WO2010111663A1 (en) * 2009-03-26 2010-09-30 Ethicon, Inc. Human umbilical cord tissue cells as therapy for alzheimer' s disease
AU2010279913B2 (en) * 2009-08-07 2016-04-28 Kyoto University Method of efficiently establishing induced pluripotent stem cells
JPWO2011096482A1 (ja) * 2010-02-03 2013-06-13 国立大学法人 東京大学 多能性幹細胞を用いた免疫機能再建法

Also Published As

Publication number Publication date
RU2014129756A (ru) 2016-02-10
AU2012355749A1 (en) 2014-07-31
KR20140113691A (ko) 2014-09-24
BR112014015342A2 (pt) 2017-06-13
MX2014007473A (es) 2014-12-05
WO2013095909A1 (en) 2013-06-27
HK1203553A1 (en) 2015-10-30
CA2859756A1 (en) 2013-06-27
US20130157365A1 (en) 2013-06-20
EP2794855A1 (en) 2014-10-29
SG11201403369XA (en) 2014-10-30
US20140178989A1 (en) 2014-06-26
CN104136604A (zh) 2014-11-05
JP2015502759A (ja) 2015-01-29
PH12014501426A1 (en) 2014-09-22

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]