MX359002B - Metodo y composicion para prevenir la interrupcion y agregacion de celulas madre. - Google Patents
Metodo y composicion para prevenir la interrupcion y agregacion de celulas madre.Info
- Publication number
- MX359002B MX359002B MX2014012260A MX2014012260A MX359002B MX 359002 B MX359002 B MX 359002B MX 2014012260 A MX2014012260 A MX 2014012260A MX 2014012260 A MX2014012260 A MX 2014012260A MX 359002 B MX359002 B MX 359002B
- Authority
- MX
- Mexico
- Prior art keywords
- aggregation
- cell disruption
- composition
- stem cell
- present
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/71—Oxidoreductases (EC 1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a un método para evitar la interrupción y agregación de células madre. Además, se proporciona una composición de células madre para la administración intravascular, en la que, las células madre se suspenden en una solución que contiene aspirina. Además, se proporciona una composición para evitar la interrupción o agregación de células madre, en las que las células madre se suspenden en una solución que contiene aspirina. De acuerdo a la presente invención, se puede evitar la interrupción y agregación de células durante la transportación y almacenamiento, de tal manera que las células madre administradas puedan alcanzar de manera estable el tejido diana y exhibir la actividad de las mismas de una manera más eficiente, de este modo aumenta notablemente el efecto de la terapia celular con células madre.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120038828 | 2012-04-13 | ||
| PCT/KR2013/003141 WO2013154404A1 (ko) | 2012-04-13 | 2013-04-15 | 줄기세포의 파쇄 및 응집 방지 방법 및 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014012260A MX2014012260A (es) | 2015-07-14 |
| MX359002B true MX359002B (es) | 2018-09-12 |
Family
ID=49327896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012260A MX359002B (es) | 2012-04-13 | 2013-04-15 | Metodo y composicion para prevenir la interrupcion y agregacion de celulas madre. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9433645B2 (es) |
| EP (1) | EP2837682B1 (es) |
| JP (1) | JP5931277B2 (es) |
| KR (1) | KR101467481B1 (es) |
| CN (1) | CN104755609B (es) |
| AU (1) | AU2013247455A1 (es) |
| HK (1) | HK1208498A1 (es) |
| MX (1) | MX359002B (es) |
| WO (1) | WO2013154404A1 (es) |
| ZA (1) | ZA201407412B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2840133B1 (en) * | 2012-04-18 | 2017-06-14 | Jeong Chan Ra | Method for manufacturing stem cell having appropriate size for intravascular administration |
| KR101583569B1 (ko) * | 2013-05-15 | 2016-01-08 | 라정찬 | 정맥 투여용 줄기세포 조성물 |
| WO2016121840A1 (ja) * | 2015-01-29 | 2016-08-04 | 国立大学法人 東京大学 | 細胞の培養方法、細胞の凝集体、細胞凝集制御剤、及び、培地 |
| KR101648915B1 (ko) | 2016-05-16 | 2016-08-17 | 주식회사 디지레이 | 줄기세포의 응집방지 방법 및 그 조성물 |
| EP3492585A4 (en) * | 2016-07-29 | 2020-01-01 | Jeong Chan Ra | PROCESS FOR PRODUCING MESENCHYMAL STEM CELLS THAT INHIBIT CANCER CELL PROLIFERATION |
| CN109689855B (zh) * | 2016-12-27 | 2021-10-26 | 富有干细胞株式会社 | 从三维多孔支架回收培养细胞的方法 |
| EP3608400A4 (en) * | 2017-04-03 | 2021-01-06 | Kaneka Corporation | CELL POPULATION WITH MESENCHYMAL STEM CELLS, METHOD OF MANUFACTURING THEREFORE AND PHARMACEUTICAL COMPOSITION |
| US11692172B2 (en) * | 2017-06-26 | 2023-07-04 | Mackay Memorial Hosptal | Formulation comprising extracellular vesicles, method for producing the same, and uses thereof |
| CN109423476A (zh) * | 2017-08-21 | 2019-03-05 | 青岛瑞思德生物科技有限公司 | 用于制备脂肪间充质干细胞的试剂盒 |
| KR102233568B1 (ko) * | 2019-12-13 | 2021-03-30 | 주식회사 알바이오 | 항암 바이러스가 도입된 중간엽 줄기세포의 세포 생존능을 향상시키는 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002357135C1 (en) | 2001-12-07 | 2009-01-22 | Macropore Biosurgery, Inc. | Systems and methods for treating patients with processed lipoaspirate cells |
| WO2004074457A2 (en) | 2003-02-20 | 2004-09-02 | Macropore Biosurgery, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
| JP4722041B2 (ja) * | 2003-06-18 | 2011-07-13 | サイトリ セラピューティクス インコーポレイテッド | オートロガス脂肪導入増進における、脂肪組織由来細胞の使用方法 |
| DK1789534T3 (en) | 2004-08-16 | 2014-11-17 | Cellres Corp Pte Ltd | ISOLATION OF stem / progenitor cells FOSTER HINDE FROM an umbilical cord |
| KR100818214B1 (ko) | 2006-09-29 | 2008-04-01 | 재단법인서울대학교산학협력재단 | 인간 태반조직의 양막 또는 탈락막 유래 다분화능 줄기세포및 그 제조방법 |
| KR100795708B1 (ko) | 2006-12-26 | 2008-01-17 | 주식회사 알앤엘바이오 | 인간 양막 상피세포 유래 성체 줄기세포의 분리 및 배양방법 |
| ES2325715B1 (es) * | 2007-08-03 | 2010-06-17 | Genetrix, S.L. | Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca. |
| US20120122816A1 (en) * | 2009-02-05 | 2012-05-17 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for organ preservation |
| WO2011043524A1 (ko) * | 2009-10-08 | 2011-04-14 | 주식회사 알앤엘바이오 | 인간 유래 성체 줄기세포를 함유하는 항암용 조성물 |
| US20120020931A1 (en) | 2010-06-02 | 2012-01-26 | Rutgers, The State University Of New Jersey | Therapeutic encapsulated embryonic stem cells and mesenchymal stromal cells |
| CN103502437B (zh) * | 2010-07-20 | 2016-08-03 | 南加州大学 | 高端粒酶活性的骨髓间充质干细胞、其制造方法和基于其的药物和治疗方法 |
| KR101293637B1 (ko) * | 2011-01-14 | 2013-08-13 | 서울대학교병원 | 줄기세포의 부유배양용 조성물 |
-
2013
- 2013-04-15 EP EP13775784.5A patent/EP2837682B1/en not_active Not-in-force
- 2013-04-15 MX MX2014012260A patent/MX359002B/es active IP Right Grant
- 2013-04-15 KR KR1020130041022A patent/KR101467481B1/ko active IP Right Grant
- 2013-04-15 US US14/394,402 patent/US9433645B2/en active Active
- 2013-04-15 CN CN201380025698.6A patent/CN104755609B/zh not_active Expired - Fee Related
- 2013-04-15 JP JP2015505655A patent/JP5931277B2/ja active Active
- 2013-04-15 AU AU2013247455A patent/AU2013247455A1/en not_active Abandoned
- 2013-04-15 WO PCT/KR2013/003141 patent/WO2013154404A1/ko active Application Filing
-
2014
- 2014-10-13 ZA ZA2014/07412A patent/ZA201407412B/en unknown
-
2015
- 2015-09-21 HK HK15109256.3A patent/HK1208498A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201407412B (en) | 2016-09-28 |
| CN104755609A (zh) | 2015-07-01 |
| MX2014012260A (es) | 2015-07-14 |
| CN104755609B (zh) | 2017-09-05 |
| WO2013154404A1 (ko) | 2013-10-17 |
| KR101467481B1 (ko) | 2014-12-01 |
| EP2837682B1 (en) | 2017-09-20 |
| AU2013247455A1 (en) | 2014-11-20 |
| KR20130116213A (ko) | 2013-10-23 |
| US20150118194A1 (en) | 2015-04-30 |
| EP2837682A4 (en) | 2015-09-02 |
| JP2015513918A (ja) | 2015-05-18 |
| EP2837682A1 (en) | 2015-02-18 |
| US9433645B2 (en) | 2016-09-06 |
| HK1208498A1 (en) | 2016-03-04 |
| JP5931277B2 (ja) | 2016-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |