KR102015676B1 - 항산화제를 포함하는 피부 충전제 조성물 - Google Patents

항산화제를 포함하는 피부 충전제 조성물 Download PDF

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Publication number
KR102015676B1
KR102015676B1 KR1020147000002A KR20147000002A KR102015676B1 KR 102015676 B1 KR102015676 B1 KR 102015676B1 KR 1020147000002 A KR1020147000002 A KR 1020147000002A KR 20147000002 A KR20147000002 A KR 20147000002A KR 102015676 B1 KR102015676 B1 KR 102015676B1
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South Korea
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vitamin
composition
months
hydrogel
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KR1020147000002A
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Korean (ko)
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KR20140072008A (ko
Inventor
푸티엔 리우
니콜라스 제이. 마네시스
시아오지에 유
아테네 완 치에 찬
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알러간, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/58—Materials at least partially resorbable by the body
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Materials Engineering (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
KR1020147000002A 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물 Expired - Fee Related KR102015676B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493309P 2011-06-03 2011-06-03
US61/493,309 2011-06-03
PCT/US2012/040459 WO2012167079A2 (en) 2011-06-03 2012-06-01 Dermal filler compositions including antioxidants

Related Child Applications (1)

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KR1020197024533A Division KR102154944B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물

Publications (2)

Publication Number Publication Date
KR20140072008A KR20140072008A (ko) 2014-06-12
KR102015676B1 true KR102015676B1 (ko) 2019-10-21

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KR1020207025510A Expired - Fee Related KR102238406B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물
KR1020197024533A Expired - Fee Related KR102154944B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물
KR1020147000002A Expired - Fee Related KR102015676B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물
KR1020217009866A Expired - Fee Related KR102312056B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물

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KR1020207025510A Expired - Fee Related KR102238406B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물
KR1020197024533A Expired - Fee Related KR102154944B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물

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KR1020217009866A Expired - Fee Related KR102312056B1 (ko) 2011-06-03 2012-06-01 항산화제를 포함하는 피부 충전제 조성물

Country Status (10)

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US (5) US9149422B2 (enExample)
EP (3) EP3536307B1 (enExample)
JP (5) JP6009550B2 (enExample)
KR (4) KR102238406B1 (enExample)
CN (2) CN103702659B (enExample)
AU (2) AU2012262047A1 (enExample)
CA (3) CA3133676A1 (enExample)
ES (1) ES2738208T3 (enExample)
RU (2) RU2624239C2 (enExample)
WO (1) WO2012167079A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200106224A (ko) * 2011-06-03 2020-09-11 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
KR20220146299A (ko) 2021-04-22 2022-11-01 주식회사 현대바이오랜드 비타젠을 포함하는 헤어케어용 조성물

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2818184B1 (en) 2007-11-16 2018-10-31 Allergan, Inc. Compositions and methods for treating Purpura
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
JP5749283B2 (ja) 2010-03-12 2015-07-15 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｉｎｄｕｓｔｒｉｅ Ｓａｓ 皮膚状態を改善するための流体組成物
ES2585388T5 (es) 2010-03-22 2019-08-08 Allergan Inc Hidrogeles reticulados de polisacárido y proteína-polisacárido para aumento de tejido blando
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
ES2777176T3 (es) * 2011-08-25 2020-08-04 Allergan Industrie Sas Composiciones de material de relleno dérmico que incluyen antioxidantes
AU2015275319B2 (en) * 2011-08-25 2017-09-07 Allergan Industrie, Sas Dermal filler compositions including antioxidants
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
AU2015255254B2 (en) * 2011-09-14 2017-07-06 Allergan Industrie, Sas Dermal filler compositions for fine line treatment
WO2013040242A2 (en) * 2011-09-14 2013-03-21 Allergan, Inc. Dermal filler compositions for fine line treatment
RU2638713C2 (ru) * 2011-12-08 2017-12-15 Аллерган, Инк. Композиции кожных наполнителей
US20150306237A1 (en) * 2012-12-19 2015-10-29 University Of Geneva Hyaluronic acid-antioxidant conjugates and their uses
US20140315828A1 (en) 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
CA2910325A1 (en) * 2013-04-25 2014-10-30 Aluron Biopharma Inc. Crosslinked hyaluronic acid compositions
US9421198B2 (en) 2013-07-30 2016-08-23 Teoxane Composition comprising hyaluronic acid and mepivacaine
US10722444B2 (en) 2014-09-30 2020-07-28 Allergan Industrie, Sas Stable hydrogel compositions including additives
FR3029928B1 (fr) * 2014-12-15 2018-03-09 Teoxane Gel reticule
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
EP3653232A1 (en) 2015-02-13 2020-05-20 Allergan Industrie, SAS Implants for sculpting, augmenting or correcting facial features such as the chin
US20170312401A1 (en) * 2016-04-30 2017-11-02 Bvw Holding Ag Spin trap anti-adhesion hydrogels
KR101866310B1 (ko) * 2016-05-31 2018-06-11 주식회사 글랜젠 생체 내 지속성 및 항산화 작용이 향상된 진피 충전재 조성물 및 이의 제조방법
WO2017220622A1 (en) 2016-06-23 2017-12-28 Galderma S.A. Cyclodextrin-grafted cross-linked hyaluronic acid complexed with active drug substances and uses thereof
KR101866312B1 (ko) * 2016-07-15 2018-06-11 주식회사 글랜젠 생체 내 지속성 및 항산화 작용이 향상된 폴리디옥시리보뉴클레오티드계 진피 충전재 조성물 및 이의 제조방법
EP3503841A4 (en) 2016-08-24 2020-04-22 Allergan, Inc. CO-CROSSLINKED HYALURONIC ACID-FIBROIN HYDROGELS FOR IMPROVING THE SUSTAINABILITY OF TISSUE GRAFTS AND FOR INCREASING SOFT TISSUES
GB201616838D0 (en) * 2016-10-04 2016-11-16 Nat Univ Ireland Hyaluronan compositions, and uses thereof in treatment of interstitial cystitis
KR102048119B1 (ko) * 2017-01-25 2019-11-22 손유나 피부 노화 방지용 키트 및 피부미용 시스템
AU2018216540B2 (en) * 2017-02-02 2021-02-18 Amtixbio Co., Ltd. Hydrogel using, as substrate, hyaluronic acid derivative modified with gallol group and use thereof
JP7216006B2 (ja) 2017-03-22 2023-01-31 ジェネンテック， インコーポレイテッド ヒドロゲル架橋ヒアルロン酸プロドラッグ組成物及び方法
JP6785387B2 (ja) 2017-05-24 2020-11-18 スリーエム イノベイティブ プロパティズ カンパニー 接着剤物品並びに同物品を製造及び使用する方法
KR20200032103A (ko) * 2017-06-26 2020-03-25 이발브드 바이 네이처, 인크. 실크-히알루론산 기초 조직 충전제 및 이를 사용하는 방법
US20230190997A1 (en) 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
CN107629142A (zh) * 2017-09-20 2018-01-26 常州药物研究所有限公司 修饰的交联葡聚糖微球及其制备方法以及含此微球的医用组合物
KR102017741B1 (ko) 2017-12-01 2019-09-03 주식회사 리엔젠 비타민 c 유도체를 고정화한 폴리감마 글루탐산계 진피 충전제 조성물 및 그 제조방법
KR102144479B1 (ko) 2018-05-24 2020-08-13 주식회사 덱스레보 조직 수복용 조성물 및 이의 제조방법
EP3806918A1 (en) 2018-06-15 2021-04-21 Croma-Pharma Gesellschaft m.b.H. Stabilized hyaluronic acid
CA3101408A1 (en) 2018-06-15 2019-12-19 Croma-Pharma Gmbh Hydrogel composition comprising a crosslinked polymer
CN109316628B (zh) * 2018-09-21 2021-04-20 广州远想生物科技有限公司 一种凝胶及其制备方法和应用
CN113677320A (zh) 2018-12-19 2021-11-19 自然进化公司 丝-透明质酸组织填充物及其制备和使用方法
CA3122116C (en) * 2018-12-20 2023-07-18 Lg Chem, Ltd. Filler having excellent filler properties comprising hyaluronic acid hydrogel
CN110467689A (zh) * 2019-09-09 2019-11-19 山东众山生物科技有限公司 一种透明质酸衍生物及其制备方法
EP4077402B1 (en) 2019-12-19 2024-05-01 Croma-Pharma GmbH Thiol-modified hyaluronan and hydrogel comprising the crosslinked hyaluronan
US20230040919A1 (en) * 2019-12-26 2023-02-09 Allergan, Inc. Crosslinked ha-collagen hydrogels as dermal fillers
CN111281887A (zh) * 2020-03-03 2020-06-16 中山大学 一种适于搭载人脐带华顿氏胶间充质干细胞的温敏性水凝胶复合物及其应用
CN111253504A (zh) * 2020-03-19 2020-06-09 上海缓释新材料科技有限公司 一种无毒副作用的维生素a衍生物及其制备方法
KR102162724B1 (ko) * 2020-03-24 2020-10-07 바이오플러스 주식회사 가교 히알루론산 겔 및 이의 제조 방법
US11058640B1 (en) * 2020-04-07 2021-07-13 Amc Group, Llc Hyaluronate compositions and soft tissue fillers
KR102193951B1 (ko) * 2020-05-25 2020-12-24 주식회사 울트라브이 필러용 생분해성 고분자 미세입자의 제조 방법, 및 이를 포함하는 주사제의 제조 방법
WO2021243182A1 (en) * 2020-05-28 2021-12-02 University Of Montana Devices comprising hyaluronic acid and silk fibroin
CN113527537B (zh) * 2021-07-14 2022-04-08 润辉生物技术（威海）有限公司 一种左旋维生素c透明质酸酯衍生物及其制备方法和应用
WO2024219893A1 (ko) 2023-04-19 2024-10-24 주식회사 파마리서치 조직 수복용 조성물
KR102634337B1 (ko) * 2023-07-24 2024-02-07 마테리아노바코리아 주식회사 생분해성고분자 미세 입자 제조방법, 생분해성 고분자미세입자, 및 조직수복용 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007018124A1 (ja) 2005-08-11 2007-02-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo コラーゲン産生増強剤とその用途
US20090143331A1 (en) 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity
US20100316683A1 (en) 2006-12-06 2010-12-16 Pierre Fabre Dermo-Cosmetique Hyaluronic acid gel for intradermal injection

Family Cites Families (343)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2128827A (en) 1938-03-09 1938-08-30 Frank B Killian Method and apparatus for manufacturing thin rubber articles
CA807629A (en) 1966-06-30 1969-03-04 Eigen Edward Lotion and detergent compositions
JPS4838158B1 (enExample) 1970-10-05 1973-11-15
CA949965A (en) 1971-12-03 1974-06-25 Robert H. Marchessault Method of preparing cross-linked starch and starch derivatives
US3949073A (en) 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
CA1073360A (en) 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
US4233360A (en) 1975-10-22 1980-11-11 Collagen Corporation Non-antigenic collagen and articles of manufacture
JPS581933Y2 (ja) 1979-04-23 1983-01-13 株式会社日本製鋼所 ケ−ブルのクランプ装置
JPS55153711A (en) 1979-05-19 1980-11-29 Pola Chem Ind Inc Cosmetic lotion
US4279812A (en) 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
JPS6052129B2 (ja) 1979-10-04 1985-11-18 呉羽化学工業株式会社 医療用コラ−ゲン繊維の製造法
US4424208A (en) 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4501306A (en) 1982-11-09 1985-02-26 Collagen Corporation Automatic syringe filling system
SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
GB8418772D0 (en) 1984-07-24 1984-08-30 Geistlich Soehne Ag Chemical substances
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4636524A (en) 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US5278059A (en) 1985-12-04 1994-01-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaki Kenkyujo Polypeptide possessing cyclomaltodextrin glucanotransferase activity
US4803075A (en) 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
FR2608456B1 (fr) 1986-12-18 1993-06-18 Mero Rousselot Satia Microcapsules a base de gelatine et de polysaccharides et leur procede d'obtention
US5091171B2 (en) 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US5385938B1 (en) 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
FR2623167B2 (fr) 1987-08-14 1992-08-07 Genus Int Perfectionnement aux articles munis d'articulations elastiques se rigidifiant lors de leur mise en tension
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5614587A (en) 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5643464A (en) 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
US5565519A (en) 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
SE462587B (sv) 1988-11-30 1990-07-23 Wiklund Henry & Co Anordning vid maerkning av arbetsstycken med skrift- eller andra tecken
JPH02215707A (ja) 1989-02-15 1990-08-28 Chisso Corp 皮膚化粧料
EP0398484B1 (en) 1989-05-19 1995-05-31 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Alpha-glycosyl-L-ascorbic acid, and its preparation and uses
EP0416250A3 (en) 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
CA2023922A1 (en) 1989-09-05 1991-03-06 James M. Curtis Method of manufacturing an implantable article provided with a micropillared surface
JP2832848B2 (ja) 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途
CA1340994C (en) 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5246698A (en) 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
JP3115625B2 (ja) 1991-03-30 2000-12-11 帝國製薬株式会社 リドカイン含有外用貼付剤
US5314874A (en) 1991-04-19 1994-05-24 Koken Co., Ltd. Intracorporeally injectable composition for implanting highly concentrated cross-linked atelocollagen
JP3072535B2 (ja) 1991-10-21 2000-07-31 株式会社林原生物化学研究所 ５−Ｏ−α−Ｄ−グルコピラノシル−Ｌ−アスコルビン酸とその製造方法並びに用途
US5272136A (en) 1991-10-12 1993-12-21 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 5-0-α-D-Glucopyranosyl-L-ascorbic acid, and its preparation and uses
JP3134235B2 (ja) 1991-10-23 2001-02-13 株式会社林原生物化学研究所 ２−Ｏ−α−Ｄ−グルコピラノシル−Ｌ−アスコルビン酸高含有物の製造方法
JP3134236B2 (ja) 1992-01-30 2001-02-13 株式会社林原生物化学研究所 α−グリコシル−Ｌ−アスコルビン酸高含有物の製造方法とその製造のための分離システム
ES2152248T3 (es) 1992-02-28 2001-02-01 Collagen Corp Composiciones de colageno de alta concentracion.
IT1260154B (it) 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
EP0680525B1 (en) 1993-01-20 1997-05-07 E.R. SQUIBB & SONS, INC. Fibres
DE784487T1 (de) 1993-03-19 1999-11-04 Q-Med Ab, Uppsala Ein präparat und ein verfahren zur gewebevermehrung
EP0637450A3 (en) 1993-08-04 1995-04-05 Collagen Corp Method and composition for resuscitation of hereditary tissue.
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US5616568A (en) 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
CA2146090C (en) 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
US5616689A (en) 1994-07-13 1997-04-01 Collagen Corporation Method of controlling structure stability of collagen fibers produced form solutions or dispersions treated with sodium hydroxide for infectious agent deactivation
AU706434B2 (en) 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
US20050186673A1 (en) 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US6962979B1 (en) 1995-03-14 2005-11-08 Cohesion Technologies, Inc. Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2733426B1 (fr) 1995-04-25 1997-07-18 Debacker Yves Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique
FR2733427B1 (fr) 1995-04-25 2001-05-25 W K Et Associes Compositions biphasiques injectables renfermant de l'acide hyaluronique, notamment utiles en chirurgies reparatrice et esthetique
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US5571503A (en) 1995-08-01 1996-11-05 Mausner; Jack Anti-pollution cosmetic composition
US6063405A (en) 1995-09-29 2000-05-16 L.A.M. Pharmaceuticals, Llc Sustained release delivery system
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
IT1277707B1 (it) 1995-12-22 1997-11-11 Chemedica Sa Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare
US5980948A (en) 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
FR2752843B1 (fr) 1996-08-30 1998-10-16 Sod Conseils Rech Applic Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
IT1287967B1 (it) 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S Preparazioni farmaceutiche per uso anestetico locale
IT1288257B1 (it) 1996-11-29 1998-09-11 Paoli Ambrosi Gianfranco De Composizione per uso cosmetico,farmaceutico o dietetico a base di un aminozucchero e/o di un acido poliidrossilico
US5866165A (en) 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
FR2759576B1 (fr) 1997-02-17 1999-08-06 Corneal Ind Implant de sclero-keratectomie pre-descemetique
FR2759577B1 (fr) 1997-02-17 1999-08-06 Corneal Ind Implant de sclerectomie profonde
US7767452B2 (en) 1997-02-20 2010-08-03 Kleinsek Don A Tissue treatments with adipocyte cells
US5935164A (en) 1997-02-25 1999-08-10 Pmt Corporaton Laminated prosthesis and method of manufacture
FR2764514B1 (fr) 1997-06-13 1999-09-03 Biopharmex Holding Sa Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique
US7192984B2 (en) 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
DE69909455T2 (de) 1998-03-27 2004-04-15 Lg Life Sciences Ltd. Polyethoxylierte ascorbinsäurederivate als neue antioxidantien und verfahren zu ihrer herstellung
JP4981198B2 (ja) 1998-03-31 2012-07-18 格 山本 グリコシル−ｌ−アスコルビン酸のアシル化誘導体
FR2780730B1 (fr) 1998-07-01 2000-10-13 Corneal Ind Compositions biphasiques injectables, notamment utiles en chirurgies reparatrice et esthetique
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
IT1301994B1 (it) 1998-08-05 2000-07-20 Jasper Ltd Liability Co Derivati dell'acido ialuronico.
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
IT1303738B1 (it) 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
DK172900B1 (da) 1998-12-18 1999-09-27 Per Julius Nielsen Præparat samt kit til brug ved intraoculære operationer
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
CA2299692C (en) 1999-03-01 2007-09-18 Johnson & Johnson Vision Care, Inc. Method of sterilization
US6767928B1 (en) 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
US7015198B1 (en) 1999-05-11 2006-03-21 Orentreich Foundation For The Advancement Of Science, Inc. Materials for soft tissue augmentation and methods of making and using same
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
IT1317091B1 (it) 2000-02-08 2003-05-26 S F I R Societa Fondaria Ind R Gel di acido ialuronico cross-linked con l-amminoacidi ol-amminoesteri bifunzionali.
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
KR20010096388A (ko) 2000-04-19 2001-11-07 진세훈 귀두확대성형재료 및 이 재료를 이용한 귀두의 확대시술방법
US6576446B2 (en) 2000-06-08 2003-06-10 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing high 2-O-α-D-glucopyranosyl-L-ascorbic acid
US6991652B2 (en) 2000-06-13 2006-01-31 Burg Karen J L Tissue engineering composite
WO2002000272A2 (en) 2000-06-29 2002-01-03 Biosyntech Canada Inc. Composition and method for the repair and regeneration of cartilage and other tissues
JP2002020259A (ja) 2000-07-05 2002-01-23 Noevir Co Ltd 皮膚外用剤
FR2811671B1 (fr) 2000-07-17 2003-02-28 Corneal Ind Hydrogel de polymere(s), resistant a la biodegration, preparation et utilisation a titre de support de regeneration tissulaire
FR2811996B1 (fr) 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
AU2001265400A1 (en) 2000-07-28 2002-02-13 Anika Therapeutics, Inc. Bioabsorbable composites of derivatized hyaluronic acid
EP1311657A2 (en) * 2000-08-21 2003-05-21 Rice University Tissue engineering scaffolds promoting matrix protein production
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US6773723B1 (en) 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
JP4187917B2 (ja) 2000-09-08 2008-11-26 独立行政法人科学技術振興機構 組織再生マトリックス用グリコサミノグリカン−コラーゲン複合体の製造方法
US6924273B2 (en) 2000-10-03 2005-08-02 Scott W. Pierce Chondroprotective/restorative compositions and methods of use thereof
AU2001294459A1 (en) 2000-10-06 2002-04-15 Jagotec Ag A controlled-release, parenterally administrable microparticle preparation
KR100375299B1 (ko) 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
EP1404516A2 (en) 2000-12-13 2004-04-07 Purdue Research Foundation Microencapsulation of drugs by solvent exchange
JP4754066B2 (ja) 2000-12-22 2011-08-24 株式会社林原生物化学研究所 抗関節障害剤
US6979440B2 (en) 2001-01-29 2005-12-27 Salvona, Llc Compositions and method for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and fabric
AUPR289601A0 (en) 2001-02-05 2001-03-01 Commonwealth Scientific And Industrial Research Organisation Method of tissue repair
US7119062B1 (en) 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
TW574301B (en) 2001-05-02 2004-02-01 Ind Tech Res Inst Manufacturing method of epoxide crosslinked polysaccharides matrix
US20050227936A1 (en) 2001-05-18 2005-10-13 Sirna Therapeutics, Inc. RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
EP1411861B1 (en) 2001-06-29 2012-04-04 Medgraft Microtech, Inc. Biodegradable injectable implants and related methods of manufacture and use
US6749841B2 (en) 2001-07-26 2004-06-15 Revlon Consumer Products Corporation Stabilized aqueous acidic antiperspirant compositions and related methods
JP4230135B2 (ja) 2001-08-21 2009-02-25 独立行政法人科学技術振興機構 多官能性架橋剤によって架橋したグリコサミノグリカン−コラーゲン複合体の製造法
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US20060189516A1 (en) 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
CA2476653C (en) 2002-02-21 2009-01-27 Encelle, Inc. Cross-linked bioactive hydrogel matrices
JP3916516B2 (ja) 2002-06-10 2007-05-16 独立行政法人科学技術振興機構 硬組織−軟組織界面再生用足場材料
US6780366B2 (en) 2002-08-15 2004-08-24 Mentor Corporation Drip retainer
KR100523953B1 (ko) 2002-08-27 2005-10-25 주식회사 엘지생명과학 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법
KR100507545B1 (ko) 2002-09-03 2005-08-09 주식회사 엘지생명과학 히알루론산 유도체 및 그의 제조방법
US20040127932A1 (en) 2002-09-12 2004-07-01 Shah Tilak M. Dip-molded polymeric medical devices with reverse thickness gradient, and method of making same
DE20221171U1 (de) 2002-09-18 2005-05-04 Pm-International Ag Kosmetische Formulierung
DE10246340A1 (de) 2002-10-04 2004-04-29 Wohlrab, David, Dr. Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung
US20040101959A1 (en) 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
CA2511484A1 (en) 2002-12-30 2004-07-22 Angiotech International Ag Silk-containing stent graft
TWI251596B (en) 2002-12-31 2006-03-21 Ind Tech Res Inst Method for producing a double-crosslinked hyaluronate material
AU2003303820A1 (en) 2003-01-31 2004-08-23 Biosphere S.P.A. Water soluble and biocompatible gels of hyaluronic acid cross-linked with bi-functional l-aminoacids or l-aminoesters
WO2004073759A1 (en) 2003-02-19 2004-09-02 Aventis Pharmaceuticals Holdings Inc. Composition and method for intradermal soft tissue augmentation
JP2006521180A (ja) 2003-03-25 2006-09-21 バイオキュア・インコーポレーテッド ヒドロゲル糸による医療装置
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
AU2003901834A0 (en) 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
JP2004323453A (ja) 2003-04-25 2004-11-18 Chisso Corp 分解性ゲル及びその製造法
AU2003235243A1 (en) 2003-05-13 2004-12-03 Mimasu Semiconductor Industry Co., Ltd. Wafer demounting method, wafer demounting device, and wafer demounting and transferring machine
KR20070012306A (ko) 2003-07-30 2007-01-25 앙테이스 에스.아. 생의학적 사용을 위한 복합체 매트릭스
EP1660013A4 (en) 2003-08-26 2011-07-20 Gel Del Technologies Inc BIOMATERIAL AND PROTEIN BIOCOACERVATES, METHODS OF MAKING AND USING THEM
US20070129430A1 (en) 2003-10-07 2007-06-07 Satomi Miyata Agent for enhancing the production of collagen, their preparation and use
NZ581804A (en) 2003-10-22 2011-10-28 Encelle Inc Bioactive hydrogel compositions for regenerating connective tissue
EP1681306B1 (en) 2003-10-29 2013-02-20 Teijin Limited Hyaluronic acid compound, hydrogel thereof and material for treating joint
AU2004289287A1 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20060141049A1 (en) 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20090148527A1 (en) 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
WO2005051444A2 (en) 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
EP1535952B1 (en) 2003-11-28 2013-01-16 Universite Louis Pasteur Method for preparing crosslinked polyelectrolyte multilayer films
US8124120B2 (en) * 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US20050142152A1 (en) 2003-12-30 2005-06-30 Leshchiner Adelya K. Polymeric materials, their preparation and use
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
DE102004002001A1 (de) 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Mittel zur Behandlung von entzündlichen Erkrankungen
WO2005074913A2 (en) 2004-01-30 2005-08-18 Angiotech International Ag Compositions and methods for treating contracture
FR2865737B1 (fr) 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
WO2005087994A1 (de) 2004-03-18 2005-09-22 Maschinenfabrik Rieter Ag Reinigungsschacht.
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US8288362B2 (en) 2004-05-07 2012-10-16 S.K. Pharmaceuticals, Inc. Stabilized glycosaminoglycan preparations and related methods
EP1753787B1 (en) 2004-05-20 2016-10-19 Mentor Worldwide LLC Method of covalently linking hyaluronan and chitosan
EP1750769B1 (en) 2004-05-20 2013-01-23 Mentor Worldwide LLC Methods for making injectable polymer hydrogels
US20050266064A1 (en) 2004-05-29 2005-12-01 Mccarthy Kathryn J Cosmetic compositions and methods
US20050287180A1 (en) 2004-06-15 2005-12-29 Chen Andrew X Phospholipid compositions and methods for their preparation and use
FR2873379B1 (fr) 2004-07-23 2008-05-16 Jerome Asius Procede de preparation d'acide hyaluronique reticule, acide hyaluronique reticule susceptible d'etre obtenu par ledit procede, implant contenant ledit acide hyaluronique reticule, et son utilisation
EP1791499A4 (en) 2004-08-13 2011-08-17 Ottawa Health Research Inst THE POWER TO IMPROVE OPHTHALMIC DEVICES AND RELEVANT PROCEDURES AND COMPOSITIONS
US20060040894A1 (en) 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid
US20060040895A1 (en) 2004-08-19 2006-02-23 Kipling Thacker Aesthetic use of hyaluronan
US7414021B2 (en) 2004-10-01 2008-08-19 Vincent Carmine Giampapa Method and composition for restoration of age related tissue loss in the face or selected areas of the body
KR100762928B1 (ko) 2004-10-29 2007-10-04 재단법인서울대학교산학협력재단 견 피브로인 나노섬유로 이루어진 부직포 형태의 골조직유도 재생용 차폐막 및 그 제조방법
NO20044818D0 (no) 2004-11-05 2004-11-05 Bioforsk As Spermin i kosmetiske preparater
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
CN101107270B (zh) 2004-11-24 2011-11-23 诺维信生物制药丹麦公司 用二乙烯基砜交联透明质酸的方法
FR2878444B1 (fr) 2004-11-30 2008-04-25 Corneal Ind Soc Par Actions Si Solutions viscoelastiques renfermant du hyaluronate de sodiu et de l'hydroxypropylmethylcellulose, preparation et utilisations
WO2006067608A1 (en) 2004-12-22 2006-06-29 Laboratoire Medidom S.A. Aqueous formulations based on sodium hyaluronate for parenteral use
US20060257488A1 (en) 2005-05-10 2006-11-16 Cytophil, Inc. Injectable hydrogels and methods of making and using same
US20060257346A1 (en) 2005-05-12 2006-11-16 Fatemeh Mohammadi Cosmetic composition for diminishing the appearance of lines and pores
EP1726299A3 (en) 2005-05-27 2007-04-18 StratoSphere Pharma AB Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
EP1888101B1 (en) 2005-06-06 2012-03-21 Georgetown University Compositions and methods for lipo modeling
US7491709B2 (en) 2005-07-01 2009-02-17 Wayne Carey Treatment with hyaluronic acid
WO2007004300A1 (ja) 2005-07-06 2007-01-11 Dr.Ci:Labo Co., Ltd. 化粧品
JP2007043960A (ja) 2005-08-10 2007-02-22 Towa Kagaku Kk ゼリー化した活力促進・老化防止食品及びその製造方法
JP4982718B2 (ja) 2005-08-31 2012-07-25 株式会社林原 美肌用の経口摂取用組成物
JP2009510168A (ja) 2005-10-03 2009-03-12 マーク エー． ピンスカイ 改善されたスキンケアのための組成物および方法
US20070104693A1 (en) 2005-11-07 2007-05-10 Quijano Rodolfo C Breast augmentation system
US20070104692A1 (en) 2005-11-07 2007-05-10 Quijano Rodolfo C Breast tissue regeneration
CA2633978A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
WO2007070547A2 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
FR2894827B1 (fr) 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
FR2895907B1 (fr) 2006-01-06 2012-06-01 Anteis Sa Gel viscoelastique a usage dermatologique
CN101002725A (zh) 2006-01-20 2007-07-25 朱炜 美容凝胶
US20070178121A1 (en) 2006-01-27 2007-08-02 Allergan, Inc. Methods for enhancing skin treatments
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US20070212385A1 (en) 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
JP2009529967A (ja) 2006-03-15 2009-08-27 サーモディクス，インコーポレイティド 天然生分解性ポリサッカライドの疎水性誘導体及びそれらの使用
US7868132B2 (en) 2006-04-25 2011-01-11 E. I. Du Pont De Nemours And Company Method for preparing multi-arm poly (ethylene glycol) amines
FR2900575B1 (fr) 2006-05-05 2008-10-17 Anteis Sa Gel biocompatible a liberation controlee, son procede de preparation et son utilisation
US8378064B2 (en) 2006-05-19 2013-02-19 Trustees Of Boston University Hydrophilic polymers as medical lubricants and gels
US20070298005A1 (en) 2006-06-22 2007-12-27 Marie-Josee Thibault Injectable composition for treatment of skin defects or deformations
WO2008003321A2 (en) 2006-07-07 2008-01-10 Novozymes Biopolymer A/S Compositions with several hyaluronic acid fractions for cosmetic use
EP1884231A1 (en) 2006-08-01 2008-02-06 Auriga International S.A. Cosmetic or pharmaceutical composition containing hyaluronic acid
ITMI20061726A1 (it) 2006-09-11 2008-03-12 Fidia Farmaceutici Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry
US20100035838A1 (en) 2006-09-19 2010-02-11 Geoffrey Kenneth Heber Cross-linked polysaccharide gels
US8968272B2 (en) 2006-10-06 2015-03-03 Lipocosm Llc Closed system and method for atraumatic, low pressure, continuous harvesting, processing, and grafting of lipoaspirate
FR2908415B1 (fr) 2006-11-10 2009-01-23 Abr Dev Sarl Acide hyaluronique reticule et son procede de preparation
WO2008063569A1 (en) 2006-11-16 2008-05-29 Coapt Systems, Inc. Co-mixed human fat and gel suspension implant material
AU2007331071A1 (en) 2006-12-11 2008-06-19 Mor Research Applications Ltd. Novel injectable chitosan mixtures forming hydrogels
KR100759091B1 (ko) 2006-12-13 2007-09-17 조강선 피부 충전제 조성물
US9597277B2 (en) 2006-12-22 2017-03-21 Croma-Pharma Gesellschaft M.B.H. Use of polymers
CA2673253C (en) 2006-12-26 2014-08-26 Romano Development Inc. Skin lightening composition for hyperpigmented skin
WO2008098007A1 (en) 2007-02-05 2008-08-14 Freedom-2, Inc. Tissue fillers and methods of using the same
CA2677498C (en) 2007-02-05 2016-05-17 Carbylan Biosurgery, Inc. Polymer formulations for delivery of bioactive agents
US7776840B2 (en) 2007-02-21 2010-08-17 Cutanea Life Sciences, Inc. Methods of use of biomaterial and injectable implant containing biomaterial
US7939578B2 (en) 2007-02-23 2011-05-10 3M Innovative Properties Company Polymeric fibers and methods of making
US8642067B2 (en) 2007-04-02 2014-02-04 Allergen, Inc. Methods and compositions for intraocular administration to treat ocular conditions
US8303941B2 (en) 2007-04-20 2012-11-06 Geologix, Inc. Chelated mineral water
US11078262B2 (en) 2007-04-30 2021-08-03 Allergan, Inc. High viscosity macromolecular compositions for treating ocular conditions
EP2155212A2 (fr) 2007-05-11 2010-02-24 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2008148967A2 (fr) 2007-05-11 2008-12-11 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
EP2155154A2 (fr) 2007-05-11 2010-02-24 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2008147867A2 (en) 2007-05-23 2008-12-04 Allergan, Inc. Cross-linked collagen and uses thereof
CA2687983A1 (en) 2007-05-23 2008-12-04 Allergan, Inc. Coated hyaluronic acid particles
WO2008148071A2 (en) 2007-05-24 2008-12-04 Nidus2, Llc Injectable dermis
ATE487441T1 (de) 2007-06-01 2010-11-15 Allergan Inc Gerät zur erzeugung des zugspannungsinduzierten wachstums von biologischem gewebe
WO2008157608A1 (en) 2007-06-18 2008-12-24 Cartlix, Inc. Composite scaffolds for tissue regeneration
WO2009005790A2 (en) 2007-06-29 2009-01-08 Carbylan Biosurgery, Inc. Sterile thiol-derivatized hyaluronic acid polymer compositions and uses thereof
FR2919185B1 (fr) 2007-07-23 2010-09-10 Ard Sa Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
EP2182971B1 (en) 2007-07-27 2013-12-18 Humacyte, Inc. Compositions comprising human collagen and human elastin and uses thereof
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US20110077737A1 (en) 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
FR2920000B1 (fr) 2007-08-13 2010-01-29 Oreal Composition cosmetique ou pharmaceutique contenant de l'acide hyaluronique, et procede cosmetique pour diminuer les signes du vieilissement
CA2734577A1 (en) 2007-08-16 2009-02-26 Carnegie Mellon University Inflammation-regulating compositions and methods
EP2033689A1 (en) 2007-08-22 2009-03-11 Italfarmacia S.r.l. Injectable dermatological composition for treatment of the wrinkles
KR100813224B1 (ko) 2007-08-24 2008-03-13 한양대학교 산학협력단 단백질 약물전달용 온도 가역성 코아세르베이트 조합 겔
FR2920968B1 (fr) 2007-09-14 2009-11-13 Oreal Procede cosmetique de traitement esthetique et/ou reparateur de la peau
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US7910134B2 (en) 2007-10-29 2011-03-22 Ayman Boutros Alloplastic injectable dermal filler and methods of use thereof
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US20090143348A1 (en) 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
FR2924615B1 (fr) 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
US9161970B2 (en) 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
US20090181104A1 (en) 2007-12-14 2009-07-16 Gino Rigotti Breast reconstruction or augmentation using computer-modeled deposition of processed adipose tissue
TW200927074A (en) 2007-12-25 2009-07-01 Univ Nat Taiwan Colloidal frame used in tissue engineering
EP2222270B1 (en) 2007-12-26 2018-11-14 Mark A. Pinsky Collagen formulations for improved skin care
CA2715288C (en) 2008-02-11 2018-06-05 Gedge Rossen Compositions and methods for implantation of adipose tissue and adipose tissue products
US20090291986A1 (en) 2008-05-22 2009-11-26 Apostolos Pappas Composition and method of treating facial skin defect
US20090297632A1 (en) 2008-06-02 2009-12-03 Waugh Jacob M Device, Methods and Compositions to Alter Light Interplay with Skin
DE102008027486B4 (de) 2008-06-10 2013-11-07 Human Med Ag Verfahren und Vorrichtung zum Trennen von Gewebezellen aus einer Flüssigkeit
DE102009055227B3 (de) 2009-12-23 2011-06-22 Human Med AG, 19061 Verfahren zur Förderung eines Fluids sowie Vorrichtung zur Erzeugung eines Volumenstromes
EP3545979A1 (en) 2008-07-02 2019-10-02 Allergan, Inc. Compositionsand methods for tissue filling and regeneration
WO2010003797A1 (en) 2008-07-09 2010-01-14 Novozymes Biopharma Dk A/S Hyaluronic acid for corneal wound healing
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
WO2010027471A2 (en) 2008-09-04 2010-03-11 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
FI20085839A0 (fi) 2008-09-08 2008-09-08 Timo Ylikomi Menetelmiä ja välineitä pehmytkudosteknologiaan
GB0816496D0 (en) 2008-09-10 2008-10-15 Zhao Xiaobin Hyaluronic acid cryogel
JP5683957B2 (ja) 2008-09-30 2015-03-11 電気化学工業株式会社 光安定化された医薬組成物
US20100098794A1 (en) 2008-10-17 2010-04-22 Armand Gerard Topical anti-wrinkle and anti-aging moisturizing cream
US20100111919A1 (en) 2008-10-31 2010-05-06 Tyco Healthcare Group Lp Delayed gelation compositions and methods of use
WO2010053918A1 (en) 2008-11-05 2010-05-14 Hancock Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
EP2365829B1 (en) 2008-11-07 2017-05-24 KLOX Technologies, Inc. Combination of an oxidant and a photoactivator for the healing of wounds
FR2938187B1 (fr) 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
ITRM20080636A1 (it) 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
WO2010065784A2 (en) 2008-12-03 2010-06-10 Jakk Group, Inc. Methods, devices, and compositions for dermal filling
FR2939799B1 (fr) 2008-12-11 2011-03-11 Sederma Sa Composition cosmetique comprenant des oligoglucuronanes acetyles.
SE533818C2 (sv) 2009-02-04 2011-01-25 Roxtec Ab Excentrisk del av en rör- eller kabelgenomföring
KR20110135949A (ko) 2009-03-05 2011-12-20 바이오미메틱 세라퓨틱스, 인크. 혈소판-유래 성장 인자 조성물 및 골연골성 결함의 치료 방법
US20100249924A1 (en) 2009-03-27 2010-09-30 Allergan, Inc. Bioerodible matrix for tissue involvement
PT2236523T (pt) 2009-03-30 2018-03-21 Scivision Biotech Inc Método para produzir ácido hialurónico reticulado
AU2010232547A1 (en) 2009-04-02 2011-10-27 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US9371402B2 (en) 2009-04-09 2016-06-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
US20110111031A1 (en) 2009-04-20 2011-05-12 Guang-Liang Jiang Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof
US20110008437A1 (en) 2009-04-20 2011-01-13 Altman Gregory H Silk Fibroin Hydrogels and Uses Thereof
US20110052695A1 (en) 2009-04-20 2011-03-03 Allergan, Inc. Drug delivery platforms comprising silk fibroin hydrogels and uses thereof
US9023369B2 (en) 2009-04-22 2015-05-05 Ralf Malessa Freeze-dried composition of active substances
US9173975B2 (en) 2009-04-24 2015-11-03 Ingeneron, Inc. Reparative cell delivery via hyaluronic acid vehicles
US9101538B2 (en) 2009-05-20 2015-08-11 Donna M. Tozzi Injectable amino-acid composition
IT1395392B1 (it) 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
MX2012002696A (es) 2009-09-03 2012-08-15 Hayashibara Biochem Lab Composicion particulada que contiene ácido 2-0-alfa-d-glucosil-l-a scórbico anhidro cristalino, procedimiento para la producción de la misma, y sus usos.
KR101122163B1 (ko) 2009-12-01 2012-03-16 (주)셀인바이오 아토피 피부염에 효과적인 히알루론산 유도체 및 그 제조방법
EP2512516B1 (en) 2009-12-18 2016-02-17 The Governing Council Of The University Of Toronto Injectable polymer composition for use as a cell delivery vehicle
EP2515867B1 (en) 2009-12-22 2018-08-08 National Cheng Kung University Cell tissue gel containing collagen and hyaluronan
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110171286A1 (en) 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171310A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171311A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US8801682B2 (en) 2010-01-27 2014-08-12 Human Med Ag Apparatus for separating tissue cells from a fluid
JP5749283B2 (ja) 2010-03-12 2015-07-15 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｉｎｄｕｓｔｒｉｅ Ｓａｓ 皮膚状態を改善するための流体組成物
ES2585388T5 (es) 2010-03-22 2019-08-08 Allergan Inc Hidrogeles reticulados de polisacárido y proteína-polisacárido para aumento de tejido blando
ES2368307B1 (es) 2010-04-28 2012-10-17 Universidade De Santiago De Compostela Hidrogeles elaborados a base de polímeros aniónicos de origen natural.
US20110295238A1 (en) 2010-05-26 2011-12-01 Human Med Ag Device for fluid jet-supported separation and suctioning of tissue cells from a biological structure
KR20110138765A (ko) 2010-06-22 2011-12-28 (주)차바이오앤디오스텍 인간지방　조직으로부터　분리한　세포와　히알루론산　유도체를　포함하는　복합필러
KR101400907B1 (ko) 2010-07-12 2014-06-10 포항공과대학교 산학협력단 조직 증강용 충전 조성물
US8900571B2 (en) 2010-08-19 2014-12-02 Allergan, Inc. Compositions and soft tissue replacement methods
US8926963B2 (en) 2010-08-19 2015-01-06 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8741281B2 (en) 2010-08-19 2014-06-03 Allergan, Inc. Compositions and soft tissue replacement methods
US8894992B2 (en) 2010-08-19 2014-11-25 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8697056B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
DE102011080218B4 (de) 2010-10-20 2014-11-20 Human Med Ag Verfahren und Vorrichtung zum Separieren von adulten Stammzellen aus Fettgewebe
ES2645860T3 (es) 2010-10-20 2017-12-11 Allergan Holdings France S.A.S. Hilos de ácido hialurónico reticulado y uso de los mismos
US9299476B2 (en) 2010-10-22 2016-03-29 Newsouth Innovations Pty Limited Polymeric material
FR2968306B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
FR2968305B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
EP2484387A1 (en) 2011-02-03 2012-08-08 Q-Med AB Hyaluronic acid composition
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
RU2624239C2 (ru) * 2011-06-03 2017-07-03 Аллерган, Инк. Составы кожного наполнителя, включая антиоксиданты
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
KR101422689B1 (ko) 2011-07-13 2014-07-23 (주)차바이오앤디오스텍 콜라겐, 히알루론산 유도체 및 포유류의 탯줄 유래 줄기세포를 포함하는 연골세포치료제
WO2013015579A2 (ko) 2011-07-26 2013-01-31 (주)차바이오앤디오스텍 콜라겐 및 히알루론산 유도체를 포함하는 의료용 복합 생체 소재
KR102034645B1 (ko) 2011-07-26 2019-10-22 주식회사 차메디텍 콜라겐 및 히알루론산 유도체를 포함하는 의료용 복합 생체 소재
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130116190A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Hyaluronic acid-collagen matrices for tissue engineering
US20130116411A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions
US20130129835A1 (en) 2011-09-06 2013-05-23 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
WO2013040242A2 (en) 2011-09-14 2013-03-21 Allergan, Inc. Dermal filler compositions for fine line treatment
GB201118586D0 (en) 2011-10-27 2011-12-07 Turzi Antoine New A-PRP medical device, manufacturing machine and process
CA2967401C (en) 2011-11-04 2022-04-12 Xiaojie Yu Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
RU2638713C2 (ru) 2011-12-08 2017-12-15 Аллерган, Инк. Композиции кожных наполнителей
US20140011980A1 (en) 2012-07-03 2014-01-09 Allergan, Inc. Methods for sterilizing compositions and resulting compositions
US10894062B2 (en) 2012-08-10 2021-01-19 Aquavit Pharmaceuticals, Inc. Vitamin supplement compositions for injection
FR2994846B1 (fr) 2012-08-29 2014-12-26 Vivacy Lab Composition, sterilisee, comprenant au moins un acide hyaluronique et de l'ascorbyl phosphate de magnesium
US10722444B2 (en) 2014-09-30 2020-07-28 Allergan Industrie, Sas Stable hydrogel compositions including additives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007018124A1 (ja) 2005-08-11 2007-02-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo コラーゲン産生増強剤とその用途
US20090110671A1 (en) 2005-08-11 2009-04-30 Satomi Miyata Agent for enhanching the production of collagen and it's use
US20100316683A1 (en) 2006-12-06 2010-12-16 Pierre Fabre Dermo-Cosmetique Hyaluronic acid gel for intradermal injection
US20090143331A1 (en) 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
박동정, Conjugarion of hyaluronic acid with ascorbic acid and evaluation of its in vitro activity on MC3T3-E1, 2008, 연세대학교 대학원, 석사학위논문

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200106224A (ko) * 2011-06-03 2020-09-11 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
KR102238406B1 (ko) * 2011-06-03 2021-04-08 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
KR20210040466A (ko) * 2011-06-03 2021-04-13 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
KR102312056B1 (ko) * 2011-06-03 2021-10-12 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
KR20220146299A (ko) 2021-04-22 2022-11-01 주식회사 현대바이오랜드 비타젠을 포함하는 헤어케어용 조성물

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