JPH0581600B1 - - Google Patents
Info
- Publication number
- JPH0581600B1 JPH0581600B1 JP1500565A JP50056589A JPH0581600B1 JP H0581600 B1 JPH0581600 B1 JP H0581600B1 JP 1500565 A JP1500565 A JP 1500565A JP 50056589 A JP50056589 A JP 50056589A JP H0581600 B1 JPH0581600 B1 JP H0581600B1
- Authority
- JP
- Japan
- Prior art keywords
- hcv
- cdna
- sequence
- clone
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12271487A | 1987-11-18 | 1987-11-18 | |
| US122,714 | 1987-11-18 | ||
| US13988687A | 1987-12-30 | 1987-12-30 | |
| US139,886 | 1987-12-30 | ||
| US16107288A | 1988-02-26 | 1988-02-26 | |
| US19126388A | 1988-05-06 | 1988-05-06 | |
| US26358488A | 1988-10-26 | 1988-10-26 | |
| US263,584 | 1988-10-26 | ||
| US27145088A | 1988-11-14 | 1988-11-14 | |
| US161072 | 1988-11-14 | ||
| US271,450 | 1988-11-14 | ||
| US191263 | 1988-11-14 |
Related Child Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4361785A Division JP2662350B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP4361786A Division JP2532805B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP4361787A Division JP2662351B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP4361784A Division JP2809956B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP5178446A Division JP2662358B2 (ja) | 1987-11-18 | 1993-06-11 | Ｎａｎｂｖの診断用薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02500880A JPH02500880A (ja) | 1990-03-29 |
| JPH0581600B1 true JPH0581600B1 (fr) | 1993-11-15 |
Family
ID=27557988
Family Applications (16)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP89500565A Expired - Lifetime JPH02500880A (ja) | 1987-11-18 | 1988-11-18 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP4361785A Expired - Lifetime JP2662350B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP4361784A Expired - Lifetime JP2809956B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP4361787A Expired - Lifetime JP2662351B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP4361786A Expired - Lifetime JP2532805B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP5178446A Expired - Lifetime JP2662358B2 (ja) | 1987-11-18 | 1993-06-11 | Ｎａｎｂｖの診断用薬 |
| JP8239921A Expired - Lifetime JP2810022B2 (ja) | 1987-11-18 | 1996-08-21 | Ｎａｎｂｖの診断用薬 |
| JP24145196A Expired - Lifetime JP3171793B2 (ja) | 1987-11-18 | 1996-08-22 | Ｎａｎｂｖの診断用薬 |
| JP9099651A Expired - Lifetime JP2810032B2 (ja) | 1987-11-18 | 1997-04-01 | Ｎａｎｂｖの診断用薬 |
| JP10111631A Pending JPH10290696A (ja) | 1987-11-18 | 1998-04-06 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP10111632A Pending JPH10290697A (ja) | 1987-11-18 | 1998-04-06 | Ｎａｎｂｖの培養法 |
| JP11157193A Pending JP2000023683A (ja) | 1987-11-18 | 1999-06-03 | Ｎａｎｂｖの診断用薬 |
| JP2005325483A Withdrawn JP2006104207A (ja) | 1987-11-18 | 2005-11-09 | Ｎａｎｂｖの診断用薬 |
| JP2005325486A Withdrawn JP2006117681A (ja) | 1987-11-18 | 2005-11-09 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP2007095590A Pending JP2007197456A (ja) | 1987-11-18 | 2007-03-30 | Ｎａｎｂｖの診断用薬 |
| JP2007179093A Pending JP2008007508A (ja) | 1987-11-18 | 2007-07-06 | Ｎａｎｂｖの診断用薬およびワクチン |
Family Applications After (15)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4361785A Expired - Lifetime JP2662350B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP4361784A Expired - Lifetime JP2809956B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬 |
| JP4361787A Expired - Lifetime JP2662351B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP4361786A Expired - Lifetime JP2532805B2 (ja) | 1987-11-18 | 1992-12-16 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP5178446A Expired - Lifetime JP2662358B2 (ja) | 1987-11-18 | 1993-06-11 | Ｎａｎｂｖの診断用薬 |
| JP8239921A Expired - Lifetime JP2810022B2 (ja) | 1987-11-18 | 1996-08-21 | Ｎａｎｂｖの診断用薬 |
| JP24145196A Expired - Lifetime JP3171793B2 (ja) | 1987-11-18 | 1996-08-22 | Ｎａｎｂｖの診断用薬 |
| JP9099651A Expired - Lifetime JP2810032B2 (ja) | 1987-11-18 | 1997-04-01 | Ｎａｎｂｖの診断用薬 |
| JP10111631A Pending JPH10290696A (ja) | 1987-11-18 | 1998-04-06 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP10111632A Pending JPH10290697A (ja) | 1987-11-18 | 1998-04-06 | Ｎａｎｂｖの培養法 |
| JP11157193A Pending JP2000023683A (ja) | 1987-11-18 | 1999-06-03 | Ｎａｎｂｖの診断用薬 |
| JP2005325483A Withdrawn JP2006104207A (ja) | 1987-11-18 | 2005-11-09 | Ｎａｎｂｖの診断用薬 |
| JP2005325486A Withdrawn JP2006117681A (ja) | 1987-11-18 | 2005-11-09 | Ｎａｎｂｖの診断用薬およびワクチン |
| JP2007095590A Pending JP2007197456A (ja) | 1987-11-18 | 2007-03-30 | Ｎａｎｂｖの診断用薬 |
| JP2007179093A Pending JP2008007508A (ja) | 1987-11-18 | 2007-07-06 | Ｎａｎｂｖの診断用薬およびワクチン |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0318216B2 (fr) |
| JP (16) | JPH02500880A (fr) |
| KR (2) | KR0138776B1 (fr) |
| CN (5) | CN1049686C (fr) |
| BR (1) | BR8807310A (fr) |
| CA (1) | CA1341629C (fr) |
| DE (2) | DE3886363T3 (fr) |
| ES (1) | ES2012739T5 (fr) |
| FI (3) | FI105652B (fr) |
| GR (1) | GR900300069T1 (fr) |
| HK (3) | HK38293A (fr) |
| HU (3) | HU216017B (fr) |
| IE (1) | IE62868B1 (fr) |
| LV (1) | LV10726B (fr) |
| NO (1) | NO304990B1 (fr) |
| NZ (1) | NZ227011A (fr) |
| UA (1) | UA42668C2 (fr) |
| WO (1) | WO1989004669A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506018A (ja) * | 2000-08-17 | 2004-02-26 | トリペップ アクチ ボラゲット | リバビリンを含むワクチンおよびその使用方法 |
Families Citing this family (256)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3886363T3 (de) * | 1987-11-18 | 2004-09-09 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | NANBV-Diagnostika |
| US5714596A (en) * | 1987-11-18 | 1998-02-03 | Chiron Corporation | NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus |
| US5698390A (en) * | 1987-11-18 | 1997-12-16 | Chiron Corporation | Hepatitis C immunoassays |
| US5712088A (en) * | 1987-11-18 | 1998-01-27 | Chiron Corporation | Methods for detecting Hepatitis C virus using polynucleotides specific for same |
| US6171782B1 (en) | 1987-11-18 | 2001-01-09 | Chiron Corporation | Antibody compositions to HCV and uses thereof |
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
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