DK1227323T4 - Ikke-A, ikke-B hepatitisvirusantigen, diagnostiske fremgangsmåder og vacciner - Google Patents
Ikke-A, ikke-B hepatitisvirusantigen, diagnostiske fremgangsmåder og vaccinerInfo
- Publication number
- DK1227323T4 DK1227323T4 DK02006640.3T DK02006640T DK1227323T4 DK 1227323 T4 DK1227323 T4 DK 1227323T4 DK 02006640 T DK02006640 T DK 02006640T DK 1227323 T4 DK1227323 T4 DK 1227323T4
- Authority
- DK
- Denmark
- Prior art keywords
- sequence
- vaccines
- nanbv
- hutch
- hcv
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 230000001900 immune effect Effects 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000037432 silent mutation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57364390A | 1990-08-25 | 1990-08-25 | |
US61636990A | 1990-11-21 | 1990-11-21 | |
US74856491A | 1991-08-21 | 1991-08-21 | |
US2009010603 | 1991-08-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK1227323T3 DK1227323T3 (da) | 2007-03-26 |
DK1227323T4 true DK1227323T4 (da) | 2011-04-26 |
Family
ID=27416160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02006640.3T DK1227323T4 (da) | 1990-08-25 | 1991-08-23 | Ikke-A, ikke-B hepatitisvirusantigen, diagnostiske fremgangsmåder og vacciner |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0544838A4 (da) |
KR (1) | KR930702365A (da) |
AT (1) | ATE346302T1 (da) |
AU (1) | AU673135B2 (da) |
CA (1) | CA2090335A1 (da) |
DE (1) | DE69133552C5 (da) |
DK (1) | DK1227323T4 (da) |
ES (1) | ES2273934T5 (da) |
WO (1) | WO1992003458A1 (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2138784T3 (es) * | 1990-12-14 | 2000-01-16 | Innogenetics Nv | Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. |
TW360711B (en) * | 1991-06-10 | 1999-06-11 | Lucky Ltd | CDNAs of Korean hepatitis C virus and polypeptides encoded thereby |
HU227547B1 (en) | 1991-06-24 | 2011-08-29 | Novartis Vaccines & Diagnostic | Hepatitis c virus (hcv) polypeptides |
ES2198514T3 (es) * | 1991-08-27 | 2004-02-01 | F. Hoffmann-La Roche Ag | Cebadores y sondas para la deteccion de la hepatitis c. |
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
DE4240980A1 (de) * | 1992-08-07 | 1994-02-10 | Boehringer Mannheim Gmbh | HCV Peptidantigene und Verfahren zur Bestimmung von HCV |
US6153378A (en) * | 1992-10-16 | 2000-11-28 | Bionova Corporation | Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus |
AU6415394A (en) * | 1993-03-25 | 1994-10-11 | Envirocon International Incorporated | Test kits and methods for rapidly testing for contamination by microorganisms |
GB9507232D0 (en) * | 1995-04-07 | 1995-05-31 | Gatsby Charitable Foundation | Plant pathogen resistance genes and uses thereof |
CN1061991C (zh) * | 1994-06-08 | 2001-02-14 | 北京医科大学 | 新型血吸虫疫苗肽(三) |
CN1068334C (zh) * | 1994-06-08 | 2001-07-11 | 北京医科大学 | 新型血吸虫疫苗肽(二) |
CN1061990C (zh) * | 1994-06-08 | 2001-02-14 | 北京医科大学 | 新型血吸虫疫苗肽(一) |
JP2005533855A (ja) | 2002-07-24 | 2005-11-10 | インターツェル・アクチェンゲゼルシャフト | 病原性ウイルスからの別のリーディングフレームによりコードされる抗原 |
US7378234B2 (en) | 2002-09-13 | 2008-05-27 | Intercell Ag | Method for isolating hepatitis C virus peptides |
DE602004029657D1 (de) | 2003-03-24 | 2010-12-02 | Intercell Ag | Verbesserte impfstoffe |
CA2530062A1 (en) | 2003-07-11 | 2005-01-20 | Intercell Ag | Hcv vaccines |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3744242A1 (de) * | 1987-02-20 | 1989-07-06 | Seelig Renate | Virusantigen, verfahren zu seiner gewinnung und anwendung in diagnose und therapie (impfstoff) |
US5032511A (en) * | 1987-03-31 | 1991-07-16 | Mitsubishi Kasei Corporation | DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens |
IE62868B1 (en) * | 1987-11-18 | 1995-03-08 | Chiron Corp | Hepatitis C virus |
AU624105B2 (en) * | 1987-11-18 | 1992-06-04 | Novartis Vaccines And Diagnostics, Inc. | Nanbv diagnostics and vaccines |
JPH04501203A (ja) * | 1988-07-06 | 1992-03-05 | ジェネラブズ インコーポレイティド | 後―輸血性,非―a,非―b型肝炎ウィルス及び抗原 |
IL91371A0 (en) * | 1988-08-24 | 1990-04-29 | Us Commerce | Clones or vectors bearing dna sequences of non-a and non-b hepatitis and a method for detecting these materials in blood |
US5191064A (en) * | 1988-09-30 | 1993-03-02 | The Research Foundation For Microbial Diseases (Osaka University) | Non-a, non-b hepatitis virus antigen peptide |
JPH02167081A (ja) * | 1988-12-21 | 1990-06-27 | Tetsuo Nakamura | 非A非B型肝炎ウイルスゲノムRNA、cDNAおよびウイルス抗原蛋白質 |
UA50829C2 (uk) * | 1989-03-17 | 2002-11-15 | Чірон Корпорейшн | Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл |
-
1991
- 1991-08-23 KR KR1019930700552A patent/KR930702365A/ko not_active Application Discontinuation
- 1991-08-23 ES ES02006640T patent/ES2273934T5/es not_active Expired - Lifetime
- 1991-08-23 EP EP91920080A patent/EP0544838A4/en not_active Withdrawn
- 1991-08-23 DE DE69133552T patent/DE69133552C5/de not_active Expired - Lifetime
- 1991-08-23 DK DK02006640.3T patent/DK1227323T4/da active
- 1991-08-23 CA CA002090335A patent/CA2090335A1/en not_active Abandoned
- 1991-08-23 AT AT02006640T patent/ATE346302T1/de not_active IP Right Cessation
- 1991-08-23 EP EP02006640A patent/EP1227323B2/en not_active Expired - Lifetime
- 1991-08-23 WO PCT/US1991/006037 patent/WO1992003458A1/en not_active Application Discontinuation
- 1991-08-23 AU AU89041/91A patent/AU673135B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ES2273934T5 (es) | 2011-05-17 |
EP0544838A4 (en) | 1997-09-10 |
ES2273934T3 (es) | 2007-05-16 |
EP1227323B1 (en) | 2006-11-22 |
EP1227323A1 (en) | 2002-07-31 |
ATE346302T1 (de) | 2006-12-15 |
DK1227323T3 (da) | 2007-03-26 |
DE69133552D1 (de) | 2007-01-04 |
EP1227323B2 (en) | 2011-01-19 |
CA2090335A1 (en) | 1992-02-26 |
EP0544838A1 (en) | 1993-06-09 |
AU673135B2 (en) | 1996-10-31 |
WO1992003458A1 (en) | 1992-03-05 |
KR930702365A (ko) | 1993-09-08 |
DE69133552C5 (de) | 2008-01-10 |
DE69133552T2 (de) | 2007-08-23 |
AU8904191A (en) | 1992-03-17 |
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