DK3274478T3 - Hcv-ns4a/modificerede ns3-polypeptider og anvendelser deraf - Google Patents
Hcv-ns4a/modificerede ns3-polypeptider og anvendelser deraf Download PDFInfo
- Publication number
- DK3274478T3 DK3274478T3 DK15888046.8T DK15888046T DK3274478T3 DK 3274478 T3 DK3274478 T3 DK 3274478T3 DK 15888046 T DK15888046 T DK 15888046T DK 3274478 T3 DK3274478 T3 DK 3274478T3
- Authority
- DK
- Denmark
- Prior art keywords
- ns4a
- hcv
- polypeptides
- modified
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
- G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
- G01N2333/186—Hepatitis C; Hepatitis NANB
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562139183P | 2015-03-27 | 2015-03-27 | |
| PCT/US2015/036941 WO2016160046A1 (en) | 2015-03-27 | 2015-06-22 | Hcv ns4a/modified ns3 polypeptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3274478T3 true DK3274478T3 (da) | 2020-11-23 |
Family
ID=57004859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15888046.8T DK3274478T3 (da) | 2015-03-27 | 2015-06-22 | Hcv-ns4a/modificerede ns3-polypeptider og anvendelser deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10267803B2 (da) |
| EP (1) | EP3274478B1 (da) |
| JP (2) | JP6859314B2 (da) |
| CN (1) | CN107735499B (da) |
| BR (1) | BR112017020539B8 (da) |
| CA (1) | CA2980718C (da) |
| DK (1) | DK3274478T3 (da) |
| ES (1) | ES2832335T3 (da) |
| RU (1) | RU2017133463A (da) |
| WO (1) | WO2016160046A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016160046A1 (en) * | 2015-03-27 | 2016-10-06 | Ortho-Clinical Diagnostics, Inc. | Hcv ns4a/modified ns3 polypeptides and uses thereof |
| CA3135428A1 (en) * | 2019-03-29 | 2020-10-08 | Trustees Of Boston University | Chimeric antigen receptor (car) modulation |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU216017B (hu) | 1987-11-18 | 1999-04-28 | Chiron Corp. | Eljárás HCV-1 polipeptidek, HCV-1 polinukleotidok, rekombináns vektorok és gazdasejtek, valamint immunesszé kit, hepatitis C vírusfertőzés elleni vakcinák, a fertőzés kimutatására szolgáló diagnosztikumok előállítására, és immunvizsgálati és vírustenyészt |
| US5256532A (en) | 1988-05-02 | 1993-10-26 | Zynaxis Technologies, Inc. | Methods, reagents and test kits for determination of subpopulations of biological entities |
| HU225068B1 (en) | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| RO117329B1 (ro) | 1991-06-24 | 2002-01-30 | Chiron Corp Emeryville | Polipeptide care contin o secventa a virusului hepatitei c |
| UA39944C2 (uk) | 1992-07-07 | 2001-07-16 | Чірон Корпорейшн | Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі |
| CA2139100C (en) * | 1993-04-27 | 2009-06-23 | Geert Maertens | New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents |
| JP3217600B2 (ja) | 1994-07-12 | 2001-10-09 | 株式会社先端生命科学研究所 | 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ |
| ATE311463T1 (de) | 1996-05-24 | 2005-12-15 | Chiron Corp | Fusionsprotein mit multiplen epitopen |
| US6211338B1 (en) | 1997-11-28 | 2001-04-03 | Schering Corporation | Single-chain recombinant complexes of hepatitis C virus NS3 protease and NS4A cofactor peptide |
| EP1141255A4 (en) * | 1999-01-08 | 2002-09-11 | Bristol Myers Squibb Co | MODIFIED FORMS OF HEPATITIS C VIRUS NS3 PROTEASE |
| MXPA02012424A (es) | 2000-06-15 | 2003-04-25 | Chiron Corp | Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. |
| US7491808B2 (en) | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| CA2491508A1 (en) * | 2002-07-02 | 2004-01-15 | Chiron Corporation | Hcv fusion proteins with modified ns3 domains |
| JP5070055B2 (ja) * | 2004-08-27 | 2012-11-07 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 改変タンパク分解性切断部位を有するｈｃｖ多エピトープ融合抗原およびその使用 |
| BRPI0708393A2 (pt) * | 2006-03-09 | 2011-05-31 | Transgene Sa | proteìna de fusão não estrutural do vìrus da hepatite c |
| US20100297607A1 (en) * | 2009-05-20 | 2010-11-25 | Jian Zheng | Reagents For HCV Antigen-Antibody Combination Assays |
| WO2014093602A1 (en) * | 2012-12-14 | 2014-06-19 | Profectus Biosciences, Inc. | Compositions and methods for treating and preventing hepatitis c virus infection |
| WO2016160046A1 (en) * | 2015-03-27 | 2016-10-06 | Ortho-Clinical Diagnostics, Inc. | Hcv ns4a/modified ns3 polypeptides and uses thereof |
-
2015
- 2015-06-22 WO PCT/US2015/036941 patent/WO2016160046A1/en active Application Filing
- 2015-06-22 RU RU2017133463A patent/RU2017133463A/ru not_active Application Discontinuation
- 2015-06-22 JP JP2018501133A patent/JP6859314B2/ja active Active
- 2015-06-22 BR BR112017020539A patent/BR112017020539B8/pt active IP Right Grant
- 2015-06-22 EP EP15888046.8A patent/EP3274478B1/en active Active
- 2015-06-22 DK DK15888046.8T patent/DK3274478T3/da active
- 2015-06-22 CN CN201580078268.XA patent/CN107735499B/zh active Active
- 2015-06-22 ES ES15888046T patent/ES2832335T3/es active Active
- 2015-06-22 CA CA2980718A patent/CA2980718C/en active Active
- 2015-06-22 US US15/025,301 patent/US10267803B2/en active Active
-
2019
- 2019-03-08 US US16/297,311 patent/US10753939B2/en active Active
-
2020
- 2020-05-11 JP JP2020083351A patent/JP2020129001A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016160046A1 (en) | 2016-10-06 |
| BR112017020539B1 (pt) | 2023-12-12 |
| CA2980718A1 (en) | 2016-10-06 |
| ES2832335T3 (es) | 2021-06-10 |
| ES2832335T8 (es) | 2021-06-23 |
| RU2017133463A (ru) | 2019-04-29 |
| JP6859314B2 (ja) | 2021-04-14 |
| JP2020129001A (ja) | 2020-08-27 |
| CA2980718C (en) | 2021-06-01 |
| EP3274478A4 (en) | 2018-08-08 |
| US10267803B2 (en) | 2019-04-23 |
| CN107735499B (zh) | 2022-05-03 |
| US20180011096A1 (en) | 2018-01-11 |
| US10753939B2 (en) | 2020-08-25 |
| EP3274478B1 (en) | 2020-09-23 |
| CN107735499A (zh) | 2018-02-23 |
| BR112017020539A2 (pt) | 2018-07-10 |
| US20190271700A1 (en) | 2019-09-05 |
| BR112017020539B8 (pt) | 2024-01-09 |
| EP3274478A1 (en) | 2018-01-31 |
| RU2017133463A3 (da) | 2019-04-29 |
| JP2018513390A (ja) | 2018-05-24 |
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