MXPA02012424A - Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. - Google Patents
Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c.Info
- Publication number
- MXPA02012424A MXPA02012424A MXPA02012424A MXPA02012424A MXPA02012424A MX PA02012424 A MXPA02012424 A MX PA02012424A MX PA02012424 A MXPA02012424 A MX PA02012424A MX PA02012424 A MXPA02012424 A MX PA02012424A MX PA02012424 A MXPA02012424 A MX PA02012424A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody combination
- hcv antigen
- combination assay
- assay
- hcv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Abstract
La presente invencion proporciona un ensayo de combinacion de antigenos de nucleo y anticuerpos NS3/4a del VHC que puede detectar tanto antigenos como anticuerpos del VHC presentes en una muestra utilizando una matriz solida individual, asi como tambien soportes solidos para inmunoensayos para el uso en el ensayo.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21208200P | 2000-06-15 | 2000-06-15 | |
US28086701P | 2001-04-02 | 2001-04-02 | |
US28081101P | 2001-04-02 | 2001-04-02 | |
PCT/US2001/019369 WO2001096875A2 (en) | 2000-06-15 | 2001-06-14 | Hcv antigen/antibody combination assay |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02012424A true MXPA02012424A (es) | 2003-04-25 |
Family
ID=27395684
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02012401A MXPA02012401A (es) | 2000-06-15 | 2001-06-14 | Inmunoensayos para anticuerpos anti-virus de hepatitis c. |
MXPA02012424A MXPA02012424A (es) | 2000-06-15 | 2001-06-14 | Ensayo de combinacion de antigenos/anticuerpos para el virus de hepatitis c. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02012401A MXPA02012401A (es) | 2000-06-15 | 2001-06-14 | Inmunoensayos para anticuerpos anti-virus de hepatitis c. |
Country Status (23)
Country | Link |
---|---|
US (5) | US6630298B2 (es) |
EP (2) | EP1354204B2 (es) |
JP (3) | JP4837229B2 (es) |
CN (3) | CN1214244C (es) |
AT (2) | ATE348337T1 (es) |
AU (2) | AU2001272945A1 (es) |
BG (1) | BG66205B1 (es) |
BR (2) | BRPI0111731C1 (es) |
CA (2) | CA2413003C (es) |
CY (2) | CY1107537T1 (es) |
CZ (1) | CZ304185B6 (es) |
DE (2) | DE60125240T3 (es) |
DK (2) | DK1354204T4 (es) |
ES (2) | ES2288969T3 (es) |
HK (2) | HK1061861A1 (es) |
HU (1) | HU228873B1 (es) |
MX (2) | MXPA02012401A (es) |
NO (1) | NO332275B1 (es) |
PL (1) | PL213363B1 (es) |
PT (2) | PT1350105E (es) |
SI (1) | SI1354204T2 (es) |
SK (1) | SK287694B6 (es) |
WO (2) | WO2001096870A2 (es) |
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EP0697888B1 (en) * | 1993-05-12 | 2003-09-17 | Chiron Corporation | Conserved motif of hepatitis c virus e2/ns1 region |
SI1354204T2 (sl) * | 2000-06-15 | 2010-09-30 | Novartis Vaccines & Diagnostic | Hcv antigen antitelo kombinacijska analiza |
US7491808B2 (en) * | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
CA2419418A1 (en) * | 2000-08-17 | 2002-02-21 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
DE10106295C1 (de) * | 2001-02-02 | 2002-08-22 | Gaifar German American Inst Fo | Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist |
AU785380B2 (en) * | 2001-03-28 | 2007-03-15 | Ortho-Clinical Diagnostics, Inc. | A hepatitis C antigen - antibody combination assay for the early detection of HCV infection |
WO2003002749A2 (en) | 2001-06-26 | 2003-01-09 | Abbott Laboratories | Methods for the simultaneous detection of hcv antigens and hcv antibodies |
US7101683B2 (en) | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
US7049060B2 (en) * | 2001-11-05 | 2006-05-23 | Ortho-Clinical Diagnostics, Inc. | HCV anti-core monoclonal antibodies |
US7332269B2 (en) * | 2001-11-11 | 2008-02-19 | Ortho-Clinical Diagnostics, Inc. | HCV core protein sequences |
FR2839555B1 (fr) * | 2002-05-10 | 2007-07-27 | Bio Rad Pasteur | Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux |
EP1546414B1 (en) * | 2002-09-09 | 2008-10-08 | Novartis Vaccines and Diagnostics, Inc. | Hcv assay |
US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
JP4668191B2 (ja) | 2003-08-20 | 2011-04-13 | アモールフィックス・ライフ・サイエンシィズ・リミテッド | タンパク質立体配座を検出するためのエピトープ保護アッセイおよび方法 |
ES2377978T3 (es) * | 2004-08-27 | 2012-04-03 | Novartis Vaccines And Diagnostics, Inc. | Mutantes de proteínas no estructurales de VHC y usos de los mismos |
EP1845378A4 (en) * | 2005-02-02 | 2008-09-17 | Peng Cui | KIT ANTIBODY DETECTION KIT AND PREPARATION METHOD THEREOF |
US7527801B2 (en) | 2005-11-22 | 2009-05-05 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and Sapovirus antigens |
US7887803B2 (en) | 2005-12-02 | 2011-02-15 | Amorfix Life Sciences | Methods and compositions to treat misfolded-SOD1 mediated diseases |
US7794692B2 (en) * | 2005-12-02 | 2010-09-14 | Amorfix Life Sciences Ltd. | Methods and compositions for detecting amyotrophic lateral sclerosis |
AU2007219615B2 (en) | 2006-03-03 | 2013-11-28 | Promis Neurosciences Inc. | Methods and compositions to treat and detect misfolded-SOD1 mediated diseases |
CN1908666B (zh) * | 2006-08-14 | 2010-05-12 | 武汉大学 | 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用 |
US8071561B2 (en) | 2007-08-16 | 2011-12-06 | Chrontech Pharma Ab | Immunogen platform |
ES2497016T3 (es) * | 2009-03-30 | 2014-09-22 | bioMérieux | Soporte sólido de detección del VHC |
US20100297607A1 (en) * | 2009-05-20 | 2010-11-25 | Jian Zheng | Reagents For HCV Antigen-Antibody Combination Assays |
BR112012025364A2 (pt) | 2010-04-07 | 2015-09-22 | Novartis Ag | método para geração de partícula semelhante a vírus de parvovírus b19 |
WO2011158174A1 (en) * | 2010-06-17 | 2011-12-22 | Koninklijke Philips Electronics N.V. | Multi epitope assay |
AU2011276328C1 (en) | 2010-07-06 | 2016-01-21 | Novartis Ag | Norovirus derived immunogenic compositions and methods |
US20120009196A1 (en) * | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Monoclonal antibodies against hepatitis c virus core protein |
CN103298941A (zh) * | 2011-01-13 | 2013-09-11 | 奥索临床诊断有限公司 | 苍白密螺旋体三联抗原 |
FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
EP3564384A1 (en) | 2013-03-14 | 2019-11-06 | Abbott Laboratories | Hcv core lipid binding domain monoclonal antibodies |
CN105228649B (zh) * | 2013-03-14 | 2019-01-18 | 雅培制药有限公司 | Hcv抗原-抗体组合测定和方法以及用在其中的组合物 |
US9790478B2 (en) | 2013-03-14 | 2017-10-17 | Abbott Laboratories | HCV NS3 recombinant antigens and mutants thereof for improved antibody detection |
CN103630690B (zh) * | 2013-12-17 | 2014-08-20 | 朱之炜 | 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法 |
DK3274478T3 (da) | 2015-03-27 | 2020-11-23 | Ortho Clinical Diagnostics K K | Hcv-ns4a/modificerede ns3-polypeptider og anvendelser deraf |
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CN111164221B (zh) * | 2017-09-27 | 2024-03-29 | 生物辐射实验室股份有限公司 | 数字化亲和连接试验 |
CN110261616B (zh) * | 2019-04-30 | 2021-07-20 | 广东菲鹏生物有限公司 | 一种丙型肝炎病毒检测试剂盒 |
CN115838420B (zh) * | 2022-10-31 | 2023-05-05 | 北京科跃中楷生物技术有限公司 | 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂 |
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2001
- 2001-06-14 SI SI200130682T patent/SI1354204T2/sl unknown
- 2001-06-14 CN CNB018112463A patent/CN1214244C/zh not_active Expired - Lifetime
- 2001-06-14 DK DK01952160.8T patent/DK1354204T4/da active
- 2001-06-14 DK DK01952156T patent/DK1350105T3/da active
- 2001-06-14 WO PCT/US2001/019156 patent/WO2001096870A2/en active IP Right Grant
- 2001-06-14 PT PT01952156T patent/PT1350105E/pt unknown
- 2001-06-14 BR BRPI0111731A patent/BRPI0111731C1/pt not_active IP Right Cessation
- 2001-06-14 DE DE60125240T patent/DE60125240T3/de not_active Expired - Lifetime
- 2001-06-14 HU HU0500444A patent/HU228873B1/hu unknown
- 2001-06-14 ES ES01952156T patent/ES2288969T3/es not_active Expired - Lifetime
- 2001-06-14 MX MXPA02012401A patent/MXPA02012401A/es active IP Right Grant
- 2001-06-14 DE DE60129598T patent/DE60129598T2/de not_active Expired - Lifetime
- 2001-06-14 PL PL365599A patent/PL213363B1/pl not_active IP Right Cessation
- 2001-06-14 CA CA2413003A patent/CA2413003C/en not_active Expired - Lifetime
- 2001-06-14 AT AT01952160T patent/ATE348337T1/de active
- 2001-06-14 CZ CZ20024058A patent/CZ304185B6/cs not_active IP Right Cessation
- 2001-06-14 PT PT01952160T patent/PT1354204E/pt unknown
- 2001-06-14 EP EP01952160A patent/EP1354204B2/en not_active Expired - Lifetime
- 2001-06-14 CN CNB018112439A patent/CN1256591C/zh not_active Expired - Lifetime
- 2001-06-14 US US09/881,239 patent/US6630298B2/en not_active Expired - Lifetime
- 2001-06-14 CA CA2412035A patent/CA2412035C/en not_active Expired - Lifetime
- 2001-06-14 BR BRPI0111682A patent/BRPI0111682B8/pt not_active IP Right Cessation
- 2001-06-14 JP JP2002510948A patent/JP4837229B2/ja not_active Expired - Lifetime
- 2001-06-14 US US09/881,654 patent/US6632601B2/en not_active Expired - Lifetime
- 2001-06-14 AT AT01952156T patent/ATE368221T1/de active
- 2001-06-14 SK SK1777-2002A patent/SK287694B6/sk not_active IP Right Cessation
- 2001-06-14 JP JP2002510953A patent/JP4834279B2/ja not_active Expired - Lifetime
- 2001-06-14 CN CNB2004100116606A patent/CN100463922C/zh not_active Expired - Lifetime
- 2001-06-14 AU AU2001272945A patent/AU2001272945A1/en not_active Abandoned
- 2001-06-14 ES ES01952160T patent/ES2277932T5/es not_active Expired - Lifetime
- 2001-06-14 WO PCT/US2001/019369 patent/WO2001096875A2/en active IP Right Grant
- 2001-06-14 EP EP01952156A patent/EP1350105B1/en not_active Expired - Lifetime
- 2001-06-14 MX MXPA02012424A patent/MXPA02012424A/es active IP Right Grant
- 2001-06-14 AU AU2001272948A patent/AU2001272948A1/en not_active Abandoned
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2002
- 2002-12-06 NO NO20025878A patent/NO332275B1/no not_active IP Right Cessation
-
2003
- 2003-01-07 BG BG107441A patent/BG66205B1/bg unknown
- 2003-08-08 US US10/637,323 patent/US6797809B2/en not_active Expired - Lifetime
- 2003-08-19 US US10/643,853 patent/US7319144B2/en not_active Expired - Lifetime
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2004
- 2004-07-06 HK HK04104878A patent/HK1061861A1/xx not_active IP Right Cessation
- 2004-07-26 US US10/899,715 patent/US7241879B2/en not_active Expired - Lifetime
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2005
- 2005-12-21 HK HK05111793.1A patent/HK1079796A1/xx not_active IP Right Cessation
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2007
- 2007-03-07 CY CY20071100319T patent/CY1107537T1/el unknown
- 2007-08-20 CY CY20071101092T patent/CY1106820T1/el unknown
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2011
- 2011-03-28 JP JP2011071150A patent/JP2011125350A/ja not_active Withdrawn
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