JP6792556B2 - 液体サンプルを分析するためのデバイス - Google Patents
液体サンプルを分析するためのデバイス Download PDFInfo
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- JP6792556B2 JP6792556B2 JP2017535632A JP2017535632A JP6792556B2 JP 6792556 B2 JP6792556 B2 JP 6792556B2 JP 2017535632 A JP2017535632 A JP 2017535632A JP 2017535632 A JP2017535632 A JP 2017535632A JP 6792556 B2 JP6792556 B2 JP 6792556B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
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- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
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- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
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- G01N13/04—Investigating osmotic effects
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N25/02—Investigating or analyzing materials by the use of thermal means by investigating changes of state or changes of phase; by investigating sintering
- G01N25/04—Investigating or analyzing materials by the use of thermal means by investigating changes of state or changes of phase; by investigating sintering of melting point; of freezing point; of softening point
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- G01—MEASURING; TESTING
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/08—Regulating or influencing the flow resistance
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- G01N2035/00178—Special arrangements of analysers
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- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Fluid Mechanics (AREA)
- Computer Hardware Design (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Eye Examination Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462053923P | 2014-09-23 | 2014-09-23 | |
| US62/053,923 | 2014-09-23 | ||
| PCT/US2015/051772 WO2016049221A1 (en) | 2014-09-23 | 2015-09-23 | Systems and methods for integration of microfluidic tear collection and lateral flow analysis of analytes of interest |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529218A JP2017529218A (ja) | 2017-10-05 |
| JP2017529218A5 JP2017529218A5 (https=) | 2018-11-01 |
| JP6792556B2 true JP6792556B2 (ja) | 2020-11-25 |
Family
ID=55581963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017535632A Expired - Fee Related JP6792556B2 (ja) | 2014-09-23 | 2015-09-23 | 液体サンプルを分析するためのデバイス |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11536707B2 (https=) |
| EP (2) | EP3198257B1 (https=) |
| JP (1) | JP6792556B2 (https=) |
| KR (1) | KR20170072188A (https=) |
| CN (1) | CN106716116B (https=) |
| AU (1) | AU2015320685B2 (https=) |
| BR (1) | BR112017005121A2 (https=) |
| CA (1) | CA2959073A1 (https=) |
| CO (1) | CO2017002710A2 (https=) |
| ES (1) | ES2828278T3 (https=) |
| MX (1) | MX2017003454A (https=) |
| WO (1) | WO2016049221A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106716116B (zh) | 2014-09-23 | 2021-04-27 | 蒂尔实验室研究有限公司 | 用于微流体泪液收集和感兴趣的分析物的横向流动分析的集成的系统和方法 |
| US10060838B2 (en) | 2015-04-09 | 2018-08-28 | Ut-Battelle, Llc | Capture probe |
| US9632066B2 (en) | 2015-04-09 | 2017-04-25 | Ut-Battelle, Llc | Open port sampling interface |
| US20200011778A1 (en) * | 2017-02-07 | 2020-01-09 | Arizona Board Of Regents On Behalf Of Arizona State University | Electrochemical osmolarity or osmolality sensor for clinical assessment |
| CN110573880B (zh) * | 2017-02-10 | 2023-05-16 | 奎多公司 | 具有受控流体流动通道的基底的横向流动测试 |
| US10969395B2 (en) * | 2017-06-02 | 2021-04-06 | Northwestern University | Epidermal microfluidic sensor for sweat collection and analysis from aquatic athletes |
| CN107202891B (zh) * | 2017-06-27 | 2019-06-28 | 江苏大学 | 一种黄曲霉毒素b1免疫快速检测装置和检测方法 |
| DE102017211451B4 (de) * | 2017-07-05 | 2019-03-21 | Robert Bosch Gmbh | Mikromechanische Sensorvorrichtung und entsprechendes Herstellungsverfahren |
| ES2927989T3 (es) | 2017-11-21 | 2022-11-14 | Mx3 Diagnostics Inc | Sistema y procedimiento de análisis de saliva |
| CN108414034A (zh) * | 2018-02-05 | 2018-08-17 | 大连理工大学 | 一种基于毛细-蒸发效应可实时监测汗液流量的微泵 |
| JP7042140B2 (ja) * | 2018-03-30 | 2022-03-25 | 株式会社Provigate | センサチップ |
| AU2019389102B2 (en) * | 2018-11-28 | 2024-08-29 | 2Pi-Sigma Corp. | Lateral flow assay with controlled conjugate and controlled flow time |
| WO2020117707A1 (en) * | 2018-12-02 | 2020-06-11 | Polymer Technology Systems, Inc. | Systems and methods for an e-gating feature in an electrochemical test strip |
| US11701036B2 (en) | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
| CN114270397B (zh) * | 2019-07-24 | 2024-12-03 | 提姆佩尔医疗有限责任公司 | 使用电特性断层成像确定流体和组织体积估计的系统和方法 |
| US12123865B2 (en) * | 2020-01-15 | 2024-10-22 | MX3 Diagnostics, Inc. | Assessment of biomarker concentration in a fluid |
| CN111366518B (zh) * | 2020-01-22 | 2022-08-16 | 苏州大学 | 一种测定聚合物膜渗透性能的方法及装置 |
| US11703436B2 (en) | 2020-01-30 | 2023-07-18 | MX3 Diagnostics, Inc. | Biological fluid sample assessment |
| CN111766181B (zh) * | 2020-06-29 | 2023-05-12 | 东北电力大学 | 原位水生态营养盐沉积物-上覆水界面迁移转化模拟系统 |
| AU2022205666A1 (en) * | 2021-01-07 | 2023-08-24 | Koniku, Inc. | System and methods for detection of volatile organic compounds in air |
| CN112973815B (zh) * | 2021-03-09 | 2022-06-03 | 西北大学 | 一种聚集非球形微游泳体的微流管道及一种过滤方法 |
| WO2022192571A1 (en) * | 2021-03-12 | 2022-09-15 | University Of Utah Research Foundation | A microfluidic microparticle-labeled impedance sensor array for enhancing bioassay sensitivity |
| CN115178310A (zh) * | 2021-04-07 | 2022-10-14 | 中国科学院上海微系统与信息技术研究所 | 用于采样与检测的液滴式微流控采样针及其制备方法 |
| CN117629836A (zh) | 2022-08-31 | 2024-03-01 | 蒂尔实验室研究有限公司 | 用于泪液渗透压的动态温度补偿的系统和方法 |
| US12435357B2 (en) | 2022-12-22 | 2025-10-07 | Kanso Diagnostics Ltd. | Diagnostic device for detecting a target nucleic acid molecule in a biological sample |
| CN116660546A (zh) * | 2023-05-31 | 2023-08-29 | 北京大学第三医院(北京大学第三临床医学院) | 一种泪液检测系统 |
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- 2015-09-23 EP EP15843475.3A patent/EP3198257B1/en active Active
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- 2015-09-23 US US15/503,823 patent/US11536707B2/en active Active
- 2015-09-23 CA CA2959073A patent/CA2959073A1/en not_active Abandoned
- 2015-09-23 EP EP20189776.6A patent/EP3792615A1/en not_active Withdrawn
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| BR112017005121A2 (pt) | 2018-07-31 |
| EP3198257A1 (en) | 2017-08-02 |
| EP3792615A1 (en) | 2021-03-17 |
| ES2828278T3 (es) | 2021-05-25 |
| WO2016049221A1 (en) | 2016-03-31 |
| KR20170072188A (ko) | 2017-06-26 |
| MX2017003454A (es) | 2017-11-13 |
| CN106716116B (zh) | 2021-04-27 |
| US11536707B2 (en) | 2022-12-27 |
| AU2015320685B2 (en) | 2021-01-28 |
| EP3198257A4 (en) | 2018-07-18 |
| CN106716116A (zh) | 2017-05-24 |
| AU2015320685A1 (en) | 2017-03-30 |
| CO2017002710A2 (es) | 2017-08-10 |
| JP2017529218A (ja) | 2017-10-05 |
| US20170248573A1 (en) | 2017-08-31 |
| EP3198257B1 (en) | 2020-08-12 |
| CA2959073A1 (en) | 2016-03-31 |
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