BRPI0720269A8 - Sistemas e métodos para coletar filme lacrimal e medir a osmolaridade do filme lacrimal. - Google Patents

Sistemas e métodos para coletar filme lacrimal e medir a osmolaridade do filme lacrimal.

Info

Publication number
BRPI0720269A8
BRPI0720269A8 BRPI0720269A BRPI0720269A BRPI0720269A8 BR PI0720269 A8 BRPI0720269 A8 BR PI0720269A8 BR PI0720269 A BRPI0720269 A BR PI0720269A BR PI0720269 A BRPI0720269 A BR PI0720269A BR PI0720269 A8 BRPI0720269 A8 BR PI0720269A8
Authority
BR
Brazil
Prior art keywords
sample
lacrimal film
collect
fluid
measure
Prior art date
Application number
BRPI0720269A
Other languages
English (en)
Inventor
Donsky Eric
Sullivan Benjamin
Original Assignee
Ocusense Inc
Tearlab Inc
Tearlab Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ocusense Inc, Tearlab Inc, Tearlab Res Inc filed Critical Ocusense Inc
Publication of BRPI0720269A2 publication Critical patent/BRPI0720269A2/pt
Publication of BRPI0720269A8 publication Critical patent/BRPI0720269A8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N13/04—Investigating osmotic effects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/101—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the tear film
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/0067—Tear or lachrymal fluid

Abstract

SISTEMAS E MÉTODOS PARA COLETAR FILME LACRIMAL E MEDIR A OSMOLARIDADE DO FILME LACRIMAL. A presente invenção refere-se a um circuito integrado para recebimento de amostra compreendendo um substrato, que recebe um volume de alíquota de uma amostra fluida, e uma região de amostra do substrato, dimensionada de modo que o volume do fluido de amostra seja suficiente para cobrir operativamente uma parte da região da amostra. A energia comunicada ao fluido de amostra é transduzida pela região da amostra, para produzir um sinal de saída, que indica as propriedades energéticas do fluido de amostra. O circuito integrado para recebimento de amostra também inclui um canal formado no substrato, o canal configurado para coletar o volume da alíquota de um fluido de amostra e transferir o volume da alíquota de fluido de amostra na região de amostra.
BRPI0720269A 2006-12-11 2007-12-11 Sistemas e métodos para coletar filme lacrimal e medir a osmolaridade do filme lacrimal. BRPI0720269A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86954306P 2006-12-11 2006-12-11
US60/869,543 2006-12-11
PCT/US2007/025277 WO2008073399A1 (en) 2006-12-11 2007-12-11 Systems and methods for collecting tear film and measuring tear film osmolarity

Publications (2)

Publication Number Publication Date
BRPI0720269A2 BRPI0720269A2 (pt) 2014-01-28
BRPI0720269A8 true BRPI0720269A8 (pt) 2016-02-16

Family

ID=39512045

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720269A BRPI0720269A8 (pt) 2006-12-11 2007-12-11 Sistemas e métodos para coletar filme lacrimal e medir a osmolaridade do filme lacrimal.

Country Status (5)

Country Link
EP (2) EP2100155B1 (pt)
BR (1) BRPI0720269A8 (pt)
ES (1) ES2911114T3 (pt)
HK (1) HK1224379A1 (pt)
WO (1) WO2008073399A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
EP3029463A1 (en) * 2011-11-30 2016-06-08 DiagnosTear Ltd Dry eye diagnostic
KR20170072188A (ko) 2014-09-23 2017-06-26 티어랩 리서치, 인코포레이티드 미세 유체 눈물 포집 및 관심 대상인 분석물의 측방 유동 분석의 통합을 위한 시스템 및 방법
CN107735026A (zh) 2015-05-01 2018-02-23 黛尔格诺斯蒂尔有限公司 测量泪液样品中泪液成分的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123701A (en) * 1976-07-01 1978-10-31 United States Surgical Corporation Disposable sample card having a well with electrodes for testing a liquid sample
US4269197A (en) * 1979-04-05 1981-05-26 Gilbard Jeffrey P Method of measuring tear osmolarity and apparatus therefor
US5143080A (en) * 1988-12-07 1992-09-01 York Kenneth K In vivo osmometer
US4951683A (en) * 1989-01-19 1990-08-28 Davis Jeffrey P Device for detecting keratoconjunctivitis sicca
US5230864A (en) * 1991-04-10 1993-07-27 Eastman Kodak Company Gravity assisted collection device
US5849208A (en) * 1995-09-07 1998-12-15 Microfab Technoologies, Inc. Making apparatus for conducting biochemical analyses
ATE227844T1 (de) * 1997-02-06 2002-11-15 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
JP2001515091A (ja) * 1997-08-29 2001-09-18 アベリー・デニソン・コーポレイション 生物学的流体を吸収する感圧接着剤
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
EP1104263A4 (en) * 1998-08-12 2008-11-19 Ocular Res Of Boston Inc MEASUREMENT OF THE CRACKING TIME OF THE TISSUE FILM
US20050032204A1 (en) * 2001-04-10 2005-02-10 Bioprocessors Corp. Microreactor architecture and methods
US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
AU2003233468A1 (en) * 2002-04-05 2003-10-27 Eyelab Group, Llc Monitoring blood substances using self-sampled tears
US6951728B2 (en) * 2002-05-10 2005-10-04 Lifescan, Inc. Multilayer reagent test strips to quantify glycated protein in a physiological sample
EP1527330A1 (en) * 2002-08-06 2005-05-04 The Regents of the University of California Tear film osmometry
US7244394B2 (en) * 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
EP1745157A4 (en) * 2004-04-12 2008-06-11 Ohio Med College METHODS AND COMPOSITIONS FOR ANALYZING ANALYTES

Also Published As

Publication number Publication date
EP3015874A1 (en) 2016-05-04
WO2008073399A1 (en) 2008-06-19
EP2100155A4 (en) 2014-04-23
EP2100155A1 (en) 2009-09-16
ES2911114T3 (es) 2022-05-17
HK1224379A1 (zh) 2017-08-18
EP2100155B1 (en) 2022-02-16
BRPI0720269A2 (pt) 2014-01-28

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: TEARLAB, INC (US)

B25D Requested change of name of applicant approved

Owner name: TEARLAB RESEARCH, INC. (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]