ATE241018T1 - Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden - Google Patents

Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden

Info

Publication number
ATE241018T1
ATE241018T1 AT98910911T AT98910911T ATE241018T1 AT E241018 T1 ATE241018 T1 AT E241018T1 AT 98910911 T AT98910911 T AT 98910911T AT 98910911 T AT98910911 T AT 98910911T AT E241018 T1 ATE241018 T1 AT E241018T1
Authority
AT
Austria
Prior art keywords
nucleotides
investigation
solution
pna probe
probe
Prior art date
Application number
AT98910911T
Other languages
English (en)
Inventor
Eileen Xiao-Feng Nie
Yuan Min Wu
Original Assignee
Ingeneus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/870,370 external-priority patent/US6060242A/en
Application filed by Ingeneus Corp filed Critical Ingeneus Corp
Application granted granted Critical
Publication of ATE241018T1 publication Critical patent/ATE241018T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
AT98910911T 1997-02-27 1998-02-23 Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden ATE241018T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80790197A 1997-02-27 1997-02-27
US08/870,370 US6060242A (en) 1997-02-27 1997-06-06 PNA diagnostic methods
PCT/IB1998/000521 WO1998038334A1 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using pna probes

Publications (1)

Publication Number Publication Date
ATE241018T1 true ATE241018T1 (de) 2003-06-15

Family

ID=27123055

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98910911T ATE241018T1 (de) 1997-02-27 1998-02-23 Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden

Country Status (13)

Country Link
EP (1) EP0975800B1 (de)
JP (1) JP4110223B2 (de)
AT (1) ATE241018T1 (de)
AU (1) AU736701B2 (de)
CA (1) CA2282704C (de)
CY (1) CY2406B1 (de)
DE (1) DE69814848T2 (de)
DK (1) DK0975800T3 (de)
ES (1) ES2202821T3 (de)
IN (1) IN188176B (de)
PT (1) PT975800E (de)
TW (1) TW389791B (de)
WO (1) WO1998038334A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69737883T2 (de) 1996-04-25 2008-03-06 Bioarray Solutions Ltd. Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
US6251591B1 (en) * 1997-02-27 2001-06-26 Lorne Park Research, Inc. Quantitative method for detecting nucleotide concentration
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
EP1137807B1 (de) * 1998-12-08 2004-09-08 Boston Probes, Inc. Verfahren, reagentiensätze und zusammenstellungen zur erkennung von elektrostatisch an matrizen gebundene nukleinsäuren
US6441152B1 (en) 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
US6656692B2 (en) * 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
WO2000056937A2 (en) * 1999-03-25 2000-09-28 Hyseq, Inc. Solution-based methods and materials for sequence analysis by hybridization
US7220541B2 (en) * 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US6265170B1 (en) * 2000-01-24 2001-07-24 Ingeneus Corporation Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
CA2421043C (en) * 2000-08-30 2012-07-31 Avi Biopharma, Inc. Method for analysis of oligonucleotide analogs
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
NZ546072A (en) 2003-09-22 2009-08-28 Bioarray Solutions Ltd Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
JP2007516843A (ja) * 2003-10-20 2007-06-28 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 分子相互作用を検出するためのナノスケール変換システム
WO2005042763A2 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
ES2546743B1 (es) 2014-03-28 2016-07-07 Institut D'investigació Biomèdica De Bellvitge (Idibell) Marcadores mitocondriales de enfermedades neurodegenerativas
BR112017005121A2 (pt) 2014-09-23 2018-07-31 Tearlab Res Inc sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3785591T2 (de) * 1986-01-10 1993-09-02 Amoco Corp Kompetitiver homogener test.
AU656965B2 (en) * 1991-04-11 1995-02-23 Dade Behring Inc. Detection of DNA/RNA by fluorescence polarization
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DE4216949C2 (de) * 1992-05-22 1997-07-24 Christoph Prof Dr Dr Cremer Nichtenzymatisches Verfahren zur In-situ-Hybridisierung bei spezifischen Proben
US20020012902A1 (en) * 1995-10-06 2002-01-31 Martin Fuchs Methods and kit for hybridization analysis using peptide nucleic acid probes

Also Published As

Publication number Publication date
EP0975800B1 (de) 2003-05-21
JP4110223B2 (ja) 2008-07-02
DE69814848T2 (de) 2004-05-06
CA2282704C (en) 2007-11-13
DE69814848D1 (de) 2003-06-26
TW389791B (en) 2000-05-11
ES2202821T3 (es) 2004-04-01
CY2406B1 (en) 2004-09-10
EP0975800A1 (de) 2000-02-02
PT975800E (pt) 2003-10-31
AU6513598A (en) 1998-09-18
AU736701B2 (en) 2001-08-02
DK0975800T3 (da) 2003-09-22
JP2001514497A (ja) 2001-09-11
IN188176B (de) 2002-08-31
CA2282704A1 (en) 1998-09-03
WO1998038334A1 (en) 1998-09-03

Similar Documents

Publication Publication Date Title
ATE241018T1 (de) Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden
AR011901A1 (es) Evaluacion de nucleotidos en solucion utilizando sondas pna
ATE325892T1 (de) Multiparameter fluoreszenz in situ hybridisierung
KR970707299A (ko) 다중 특이적 핵산 서열의 동시 검출 및 정량을 위한 조성물 및 방법(Compositions and Methods for the Simultaneous Detection and Quantification of Multiple Specific Nucleic Acid Sequences)
ATE414096T1 (de) Verfahren zum nachweis und zur quantifizierung von analyten in komplexen mischungen
DK0970240T3 (da) Kunstig fejlparringshydridisering
CA2295333A1 (en) Assaying nucleotides in solution using a fluorescent intensity quenching effect
DE69233630D1 (de) Sätze von HIV Sonden für Solution Sandwich Hybridationsverfahren
DE69333073D1 (de) Verwendungen von fluoreszierenden n-nukleosiden und dessen analogen
ATE216728T1 (de) Verfahren zur präparierung und hybridisierung von spezifischen proben
ATE267267T1 (de) Verfahren zur quantitativen bestimmung der genexpression mit hilfe der multiplexen competitiven reversen-transkriptase polymerase kettenreaktion
DE68928853T2 (de) Befestigung von sequenzspezifischen proben
ATE219153T1 (de) Erkennung und identifizierung von menschlichem papillomavirus durch pcr und typ-spezifischer reverser hybridisierung
ATE321879T1 (de) Verfahren und strukturen, in welchen chemisch markierte nichtradioaktive polynukleotidesonden benutzt werden
ATE174065T1 (de) Simultane sequenzierung von nukleinsäuren
ATE290606T1 (de) Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen
ATE321886T1 (de) Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe
SE8700821D0 (sv) Quantitative determination of nucleic acid molecules and the reagent kit used
DE59712871D1 (de) Heterocyclische verbindungen und deren verwendung in der detektion von nucleinsäuren
DE69709804T2 (de) Nachweis von nukleotidsequenzen durch signalamplifizierung
ATE415491T1 (de) Oligonucleotide zur markierung von oligonukleotidsonden und proteine
ATE368753T1 (de) Methode zur bestimmung der zellzyklusposition
SE9500589L (sv) Nukleinsyremolekyl detektion på fasta substrat vid enmolekyl DNA sekvensering
DK0623177T3 (da) Tørret nucleinsyrehybridiseringsprobe bundet reversibelt til en fast bærer, fremgangsmåde, hvorved der anvendes en sådan probe, og kit egnet dertil
ATE40409T1 (de) Photoimmunologisches testverfahren fuer dns und rns.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0975800

Country of ref document: EP

REN Ceased due to non-payment of the annual fee