JP5904688B2 - 共生乳酸産生細菌およびその使用 - Google Patents
共生乳酸産生細菌およびその使用 Download PDFInfo
- Publication number
- JP5904688B2 JP5904688B2 JP2000565902A JP2000565902A JP5904688B2 JP 5904688 B2 JP5904688 B2 JP 5904688B2 JP 2000565902 A JP2000565902 A JP 2000565902A JP 2000565902 A JP2000565902 A JP 2000565902A JP 5904688 B2 JP5904688 B2 JP 5904688B2
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- Prior art keywords
- composition
- administration
- bacillus coagulans
- range
- cfu
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- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
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- A—HUMAN NECESSITIES
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9759498P | 1998-08-24 | 1998-08-24 | |
| US60/097,594 | 1998-08-24 | ||
| US09/370,793 US6461607B1 (en) | 1998-08-24 | 1999-08-05 | Probiotic, lactic acid-producing bacteria and uses thereof |
| US09/370,793 | 1999-08-05 | ||
| PCT/US1999/017862 WO2000010582A2 (en) | 1998-08-24 | 1999-08-06 | Probiotic, lactic acid-producing bacteria and uses thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010153465A Division JP2010215665A (ja) | 1998-08-24 | 2010-07-05 | 共生乳酸産生細菌およびその使用 |
| JP2014263310A Division JP2015061882A (ja) | 1998-08-24 | 2014-12-25 | 共生乳酸産生細菌およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002523372A JP2002523372A (ja) | 2002-07-30 |
| JP2002523372A5 JP2002523372A5 (https=) | 2006-09-07 |
| JP5904688B2 true JP5904688B2 (ja) | 2016-05-18 |
Family
ID=26793455
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000565902A Expired - Lifetime JP5904688B2 (ja) | 1998-08-24 | 1999-08-06 | 共生乳酸産生細菌およびその使用 |
| JP2010153465A Pending JP2010215665A (ja) | 1998-08-24 | 2010-07-05 | 共生乳酸産生細菌およびその使用 |
| JP2014263310A Withdrawn JP2015061882A (ja) | 1998-08-24 | 2014-12-25 | 共生乳酸産生細菌およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010153465A Pending JP2010215665A (ja) | 1998-08-24 | 2010-07-05 | 共生乳酸産生細菌およびその使用 |
| JP2014263310A Withdrawn JP2015061882A (ja) | 1998-08-24 | 2014-12-25 | 共生乳酸産生細菌およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (8) | US6461607B1 (https=) |
| EP (1) | EP1107772B1 (https=) |
| JP (3) | JP5904688B2 (https=) |
| AT (1) | ATE323503T1 (https=) |
| AU (1) | AU772332B2 (https=) |
| CA (1) | CA2341503C (https=) |
| DE (1) | DE69930944T2 (https=) |
| WO (1) | WO2000010582A2 (https=) |
Families Citing this family (245)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716435B1 (en) * | 1997-04-18 | 2004-04-06 | Ganeden Biotech, Inc. | Absorbent product containing absorbent structure and Bacillus coagulans |
| DE69832267T2 (de) * | 1997-04-18 | 2006-08-10 | Ganeden Biotech, Inc., La Jolla | Oberflächige verwendung von probiotischen bacillussporen zur verhinderung oder bekämpfung von mikrobiellen infektionen |
| AU785159B2 (en) * | 1997-04-18 | 2006-10-05 | Ganeden Biotech, Inc. | Inhibition of pathogens by bacillus coagulans strains |
| US6645506B1 (en) * | 1997-04-18 | 2003-11-11 | Ganeden Biotech, Inc. | Topical compositions containing extracellular products of Pseudomonas lindbergii and Emu oil |
| US7507402B1 (en) * | 1997-04-18 | 2009-03-24 | Ganeden Biotech, Inc. | Topical use of probiotic Bacillus spores to prevent or control microbial infections |
| US7374753B1 (en) * | 1997-06-03 | 2008-05-20 | Ganeden Biotech, Inc. | Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS |
| US6811786B1 (en) * | 1999-04-01 | 2004-11-02 | Ganeden Biotech, Inc. | Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions |
| US7767203B2 (en) | 1998-08-07 | 2010-08-03 | Ganeden Biotech, Inc. | Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption |
| US6461607B1 (en) * | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| NL1010770C2 (nl) * | 1998-12-09 | 2000-06-13 | Nutricia Nv | Preparaat dat oligosacchariden en probiotica bevat. |
| ATE285821T1 (de) * | 1999-10-08 | 2005-01-15 | Affinium Pharm Inc | Fab i inhibitoren |
| US6849256B1 (en) * | 1999-11-08 | 2005-02-01 | Ganeden Biotech Incorporated | Inhibition of pathogens by probiotic bacteria |
| SE515310C2 (sv) * | 1999-11-25 | 2001-07-09 | Wasa Medicals Ab | Tabletter innehållande mikroorganismer och förfarande för framställning därav |
| JP4580542B2 (ja) * | 2000-05-17 | 2010-11-17 | 株式會社バイオニア | 肥満又は糖尿病治療用微生物及びその微生物を含む医薬組成物 |
| US20040170617A1 (en) * | 2000-06-05 | 2004-09-02 | Finegold Sydney M. | Method of treating diseases associated with abnormal gastrointestinal flora |
| DE60031385D1 (de) * | 2000-06-28 | 2006-11-30 | B S D Bio Science Dev Snc Di O | Pharmazeutische Zusammensetzungen von Antibiotika und Fruktan-Gemische |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| WO2002022876A1 (en) | 2000-09-11 | 2002-03-21 | University Of Rochester | Method of identifying putative antibiotic resistance genes |
| IT1320772B1 (it) * | 2000-11-02 | 2003-12-10 | Proge Farm Srl | Composizione farmaceutica a base di agenti attivi contro la candidaper il trattamento di disturbi della mucosa orale e intestinale |
| DE10105347A1 (de) * | 2001-02-05 | 2002-08-22 | Nutrinova Gmbh | Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht |
| CA2444597A1 (en) * | 2001-04-06 | 2002-10-06 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| GB0124580D0 (en) | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
| WO2003039260A2 (en) * | 2001-11-05 | 2003-05-15 | Ganeden Biotech Inc | Probiotic compositions |
| US20030099626A1 (en) * | 2001-11-20 | 2003-05-29 | Health Education Corporation | Nutrient absorption enhancing compositions and methods |
| AU2002359858A1 (en) * | 2001-12-20 | 2003-07-09 | Board Of Trustees Of The University Of Arkansas | Defined competitive exclusion cultures for food borne pathogens |
| GB0212975D0 (en) * | 2002-06-06 | 2002-07-17 | Mars Uk Ltd | Mammalian animal composition |
| MXPA05003743A (es) * | 2002-10-18 | 2005-06-17 | Biogaia Ab | Metodo para mejorar la funcion inmunologica en mamiferos utilizando cepas de lactobacillus reuteri. |
| EP1575951B1 (en) | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterocyclic compounds, methods of making them and their use in therapy |
| US20040241150A1 (en) * | 2002-12-19 | 2004-12-02 | Hargis Billy M. | Defined competitive exclusion cultures for food borne pathogens |
| EP1596872B1 (en) * | 2003-01-24 | 2011-06-22 | Flora Technology Inc. | Compositions and methods for restoring bacterial flora |
| US6872565B2 (en) * | 2003-01-29 | 2005-03-29 | Biogaia Ab | Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries |
| US7517681B2 (en) * | 2003-01-29 | 2009-04-14 | Biogaia Ab | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
| WO2004069156A2 (en) * | 2003-01-30 | 2004-08-19 | The Regents Of The University Of California | Inactivated probiotic bacteria and methods of use thereof |
| US20040175459A1 (en) * | 2003-03-06 | 2004-09-09 | Te-Chih Ting | Method for producing an aqueous beverage containing sporogenous lactic bacteria |
| DE602004016831D1 (de) * | 2003-03-17 | 2008-11-13 | Affinium Pharm Inc | Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend |
| CN100372541C (zh) * | 2003-03-26 | 2008-03-05 | 康利隆日本公司 | 降低血中低分子量含氮化合物浓度的改善病情用食品 |
| CA2519927A1 (en) * | 2003-04-02 | 2004-10-21 | Pharmachem Laboratories, Inc. | Novel probiotic compositions and methods of using the same |
| US6989370B2 (en) * | 2003-05-01 | 2006-01-24 | The United States Of America As Represented By The Secretary Of Agriculture | Bacteriocins and novel bacterial strains |
| WO2004104175A2 (en) * | 2003-05-14 | 2004-12-02 | University Of Georgia Research Foundation, Inc. | Probiotic bacteria and methods |
| WO2005000034A2 (en) * | 2003-06-23 | 2005-01-06 | Agtech Products, Inc. | Lactic bacteria and its use in direct-fed microbials |
| US7749509B2 (en) * | 2003-08-29 | 2010-07-06 | Cobb And Company, Llp | Treatment of autism using probiotic composition |
| US8192733B2 (en) * | 2003-08-29 | 2012-06-05 | Cobb & Associates | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
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| US7759105B2 (en) * | 2003-08-29 | 2010-07-20 | Cobb & Company, Llp | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
| US20060177424A1 (en) * | 2003-08-29 | 2006-08-10 | Cobb Mark L | Treatment of disease states and adverse physiological conditions utilizing anti-fungal compositions |
| DK1675481T3 (da) * | 2003-10-24 | 2009-01-19 | Nutricia Nv | Synbiotisk præparat til börn |
| US7632520B2 (en) * | 2004-02-16 | 2009-12-15 | Sanjeev Khandelwal | Synergistic antibacterial formulation and to a method of making the same |
| US20050186188A1 (en) * | 2004-02-19 | 2005-08-25 | Peilin Guo | Compositions containing probiotics and polysaccharides and methods of use |
| US7807622B2 (en) * | 2004-04-23 | 2010-10-05 | Health Enhancement Products, Inc. | Composition and use of phyto-percolate for treatment of disease |
| US10166270B2 (en) | 2004-04-23 | 2019-01-01 | Zivo Bioscience, Inc. | Composition and method for affecting cytokines and NF-κB |
| US7374750B2 (en) * | 2004-05-14 | 2008-05-20 | Jennifer Albano | Probiotic containing anhydrous hair care composition |
| EP2848614A3 (en) | 2004-06-04 | 2015-07-29 | Debiopharm International SA | Acrylamide derivatives as antibiotic agents |
| WO2006009764A1 (en) | 2004-06-17 | 2006-01-26 | Amano Enzyme Usa., Ltd. | Controlled release formulations of enzymes, microorganisms, and antibodies with mucoadhesive polymers |
| US7862808B2 (en) * | 2004-07-01 | 2011-01-04 | Mead Johnson Nutrition Company | Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12 |
| EP1781308A4 (en) * | 2004-07-20 | 2009-07-01 | Cotde Ltd | NATURAL ANTIVIRUS AND COMPOSITION CONTAINING SAME |
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2005
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| US7807151B2 (en) | 2010-10-05 |
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| EP1107772A2 (en) | 2001-06-20 |
| US8187590B2 (en) | 2012-05-29 |
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