JP3382624B2 - Cox―2阻害剤のプロドラッグとしての置換ベンゼンスルホンアミド誘導体 - Google Patents
Cox―2阻害剤のプロドラッグとしての置換ベンゼンスルホンアミド誘導体Info
- Publication number
- JP3382624B2 JP3382624B2 JP53713997A JP53713997A JP3382624B2 JP 3382624 B2 JP3382624 B2 JP 3382624B2 JP 53713997 A JP53713997 A JP 53713997A JP 53713997 A JP53713997 A JP 53713997A JP 3382624 B2 JP3382624 B2 JP 3382624B2
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- sulfonyl
- methyl
- phenylisoxazol
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63151496A | 1996-04-12 | 1996-04-12 | |
US08/631,514 | 1996-04-12 | ||
PCT/US1997/005497 WO1997038986A1 (en) | 1996-04-12 | 1997-04-11 | Substituted benzenesulfonamide derivatives as prodrugs of cox-2 inhibitors |
Related Child Applications (1)
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