|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
US5171568A
(en)
|
1984-04-06 |
1992-12-15 |
Chiron Corporation |
Recombinant herpes simplex gb-gd vaccine
|
|
US4857319A
(en)
|
1985-01-11 |
1989-08-15 |
The Regents Of The University Of California |
Method for preserving liposomes
|
|
US5223263A
(en)
|
1988-07-07 |
1993-06-29 |
Vical, Inc. |
Liponucleotide-containing liposomes
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US4737323A
(en)
|
1986-02-13 |
1988-04-12 |
Liposome Technology, Inc. |
Liposome extrusion method
|
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4946683A
(en)
|
1987-11-18 |
1990-08-07 |
Vestar, Inc. |
Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
|
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5049392A
(en)
|
1989-01-18 |
1991-09-17 |
The Liposome Company, Inc. |
Osmotically dependent vesicles
|
|
ES2200016T3
(es)
|
1989-03-21 |
2004-03-01 |
Vical Incorporated |
Expresion de secuencias polinucleotidicas exogenas en un vertebrado.
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5194654A
(en)
|
1989-11-22 |
1993-03-16 |
Vical, Inc. |
Lipid derivatives of phosphonoacids for liposomal incorporation and method of use
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
FR2676072B1
(fr)
|
1991-05-03 |
1994-11-18 |
Transgene Sa |
Vecteur de delivrance d'arn.
|
|
EP0599850B1
(en)
|
1991-08-16 |
1996-01-10 |
Vical, Inc. |
Composition and method for treating cystic fibrosis
|
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
US5256555A
(en)
|
1991-12-20 |
1993-10-26 |
Ambion, Inc. |
Compositions and methods for increasing the yields of in vitro RNA transcription and other polynucleotide synthetic reactions
|
|
JPH07503372A
(ja)
|
1992-01-23 |
1995-04-13 |
バイカル・インコーポレイテッド |
生体外遺伝子導入
|
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US5981501A
(en)
*
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
|
US20050287540A1
(en)
|
1995-09-27 |
2005-12-29 |
Murphy Brian R |
Production of attenuated negative stranded RNA virus vaccines from cloned nucleotide sequences
|
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
WO1997030064A1
(en)
|
1996-02-16 |
1997-08-21 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
WO1999014346A2
(en)
|
1997-09-19 |
1999-03-25 |
Sequitur, Inc. |
SENSE mRNA THERAPY
|
|
CA2348675A1
(en)
|
1997-10-24 |
1999-05-06 |
Warren Dang |
Methods for preparing polynucleotide transfection complexes
|
|
JP2001521759A
(ja)
|
1997-11-12 |
2001-11-13 |
ザ ブリガム アンド ウィメンズ ホスピタル，インコーポレイテッド |
ヒトアミロイド前駆体タンパク質遺伝子の翻訳エンハンサーエレメント
|
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
|
AU771706B2
(en)
|
1999-07-15 |
2004-04-01 |
University Of British Columbia, The |
Methods and apparatus for preparation of lipid vesicles
|
|
US7094423B1
(en)
|
1999-07-15 |
2006-08-22 |
Inex Pharmaceuticals Corp. |
Methods for preparation of lipid-encapsulated therapeutic agents
|
|
AU7725500A
(en)
|
1999-09-30 |
2001-04-30 |
National Jewish Medical And Research Center |
Method for inhibition of pathogenic microorganisms
|
|
US6831072B2
(en)
|
1999-10-29 |
2004-12-14 |
Cygene, Inc. |
Compositions and methods of synthesis and use of novel nucleic acid structures
|
|
EP1259602A1
(en)
|
2000-01-28 |
2002-11-27 |
The Scripps Research Institute |
Methods of identifying synthetic transcriptional and translational regulatory elements, and compositions relating to same
|
|
US7468275B2
(en)
|
2000-01-28 |
2008-12-23 |
The Scripps Research Institute |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
|
US20030165849A1
(en)
|
2000-11-28 |
2003-09-04 |
Biliang Zhang |
Methods and reagents for introducing a sulfhydryl group into the 5'-terminus of RNA
|
|
DE10109897A1
(de)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
|
EP1404860B8
(en)
|
2001-05-30 |
2013-12-25 |
The Scripps Research Institute |
Delivery system for nucleic acids
|
|
EP1800697B1
(de)
|
2001-06-05 |
2010-04-14 |
CureVac GmbH |
Stabilisierte mRNA mit erhöhtem G/C-Gehalt für die Gentherapie
|
|
EP2428568B1
(en)
|
2001-09-28 |
2018-04-25 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Microrna molecules
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
|
EP1499187B1
(en)
|
2002-04-04 |
2015-06-17 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
|
CA2752143C
(en)
|
2002-05-15 |
2014-09-23 |
Sutter West Bay Hospitals |
Delivery of nucleic acid-like compounds
|
|
EP2338478B1
(en)
|
2002-06-28 |
2014-07-23 |
Protiva Biotherapeutics Inc. |
Method for producing liposomes
|
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
|
EP1873180B1
(en)
|
2002-08-14 |
2014-05-07 |
Novartis AG |
Ophthalmic device made from a radiation-curable prepolymer
|
|
US8426194B2
(en)
|
2003-01-21 |
2013-04-23 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating VEGF expression
|
|
JP4951338B2
(ja)
*
|
2003-07-16 |
2012-06-13 |
プロチバ バイオセラピューティクス インコーポレイティッド |
脂質に封入された干渉ｒｎａ
|
|
CA2533701A1
(en)
|
2003-07-31 |
2005-02-17 |
Isis Pharmaceuticals, Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding rnas
|
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
|
AU2004280143A1
(en)
|
2003-10-11 |
2005-04-21 |
Tekmira Pharmaceuticals Corporation |
Methods and compositions for enhancing innate immunity and antibody dependent cellular cytotoxicity
|
|
WO2005065721A2
(en)
|
2003-12-30 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Use of an anti-inflammatory compound for the reduction of inflammation secondary to the administration of a lipid-nucleic acid complex
|
|
ES2246694B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Nanoparticulas pegiladas.
|
|
US7745651B2
(en)
|
2004-06-07 |
2010-06-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use
|
|
AU2005252273B2
(en)
|
2004-06-07 |
2011-04-28 |
Arbutus Biopharma Corporation |
Lipid encapsulated interfering RNA
|
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
|
US8663599B1
(en)
|
2004-10-05 |
2014-03-04 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
|
KR20070067165A
(ko)
|
2004-10-13 |
2007-06-27 |
피티씨 테라퓨틱스, 인크. |
넌센스 변이 억제용 화합물, 및 이의 사용 방법
|
|
EP1817025A2
(en)
|
2004-11-23 |
2007-08-15 |
PTC Therapeutics, Inc. |
Tetrahydrocarbazoles as active agents for inhibiting vegf production by translational control
|
|
CA2590098C
(en)
|
2004-12-10 |
2015-03-31 |
Justin Hanes |
Functionalized poly (ether-anhydride) block copolymers
|
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
|
EP4174179B1
(en)
|
2005-08-23 |
2025-05-07 |
The Trustees of the University of Pennsylvania |
Rna containing modified nucleosides and methods of use thereof
|
|
EP2479254A1
(en)
|
2005-08-24 |
2012-07-25 |
The Scripps Research Institute |
Translation enhancer-element dependent vector systems
|
|
EP1968643A2
(en)
|
2005-12-16 |
2008-09-17 |
Diatos |
Cell penetrating peptide conjugates for delivering of nucleic acids into a cell
|
|
EP2591794A1
(en)
|
2006-01-05 |
2013-05-15 |
The Ohio State University Research Foundation |
MicroRNA expressions abnormalities in pancreatic endocrine and acinar tumors
|
|
EP2479286B1
(en)
|
2006-01-05 |
2013-11-13 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
|
AU2007223311C1
(en)
|
2006-03-02 |
2013-06-20 |
The Board Of Regents Of The University Of Oklahoma |
MicroRNA expression profile associated with pancreatic cancer
|
|
JP2009534309A
(ja)
|
2006-03-31 |
2009-09-24 |
マサチューセッツ インスティテュート オブ テクノロジー |
治療剤の標的化送達のためのシステム
|
|
CA2659301A1
(en)
|
2006-07-28 |
2008-02-07 |
Applera Corporation |
Dinucleotide mrna cap analogs
|
|
JP2010507361A
(ja)
|
2006-07-31 |
2010-03-11 |
キュアバック ゲーエムベーハー |
具体的には免疫刺激剤／アジュバントとしての、一般式（Ｉ）：ＧｌＸｍＧｎ、または一般式（ＩＩ）：ＣｌＸｍＣｎで表される核酸
|
|
AU2007299828C1
(en)
|
2006-09-19 |
2014-07-17 |
Interpace Diagnostics, Llc |
MicroRNAs differentially expressed in pancreatic diseases and uses thereof
|
|
CN105030654A
(zh)
|
2006-10-03 |
2015-11-11 |
阿尔尼拉姆医药品有限公司 |
含脂质的制品
|
|
CA2665343C
(en)
|
2006-10-05 |
2014-12-16 |
The Johns Hopkins University |
Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
|
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
|
AU2007314212B2
(en)
|
2006-11-01 |
2014-05-29 |
The Govt. Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services |
MicroRNA expression signature for predicting survival and metastases in Hepatocellular carcinoma
|
|
EP2121011B1
(en)
|
2006-12-06 |
2014-05-21 |
Novartis AG |
Vaccines including antigen from four strains of influenza virus
|
|
CN101622349A
(zh)
|
2006-12-08 |
2010-01-06 |
奥斯瑞根公司 |
作为治疗性干预靶标的miR-21调节的基因和途径
|
|
DE102006061015A1
(de)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC
|
|
CA2674051C
(en)
|
2006-12-28 |
2017-10-31 |
The Trustees Of The University Of Pennsylvania |
Herpes simplex virus combined subunit vaccines and methods of use thereof
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
GB0700914D0
(en)
|
2007-01-18 |
2007-02-28 |
Animal Health Inst |
Polynucleotides and uses thereof
|
|
AU2008219165A1
(en)
|
2007-02-16 |
2008-08-28 |
Merck Sharp & Dohme Corp. |
Compositions and methods for potentiated activity of biologicaly active molecules
|
|
WO2008127688A1
(en)
|
2007-04-13 |
2008-10-23 |
Hart Communication Foundation |
Synchronizing timeslots in a wireless communication protocol
|
|
AU2008247488B2
(en)
|
2007-05-04 |
2014-02-27 |
Marina Biotech, Inc. |
Amino acid lipids and uses thereof
|
|
US8415096B2
(en)
|
2007-05-23 |
2013-04-09 |
University Of South Florida |
Micro-RNAs modulating immunity and inflammation
|
|
US20090099034A1
(en)
|
2007-06-07 |
2009-04-16 |
Wisconsin Alumni Research Foundation |
Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers
|
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
|
WO2009024599A1
(en)
|
2007-08-23 |
2009-02-26 |
Novartis Ag |
Methods for detecting oligonucleotides
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
CA2891005A1
(en)
|
2007-09-28 |
2008-10-09 |
Bind Therapeutics, Inc. |
Cancer cell targeting using nanoparticles
|
|
CA2917512C
(en)
|
2007-10-12 |
2025-08-05 |
President And Fellows Of Harvard College |
VACCINE NANOTECHNOLOGY
|
|
EP2225396A4
(en)
|
2007-11-30 |
2011-03-02 |
Univ Ohio State Res Found |
PROFILING AND SCREENING OF MICRO-RNA EXPRESSION IN PERIPHERAL BLOOD IN LUNG CANCER
|
|
EA023031B1
(ru)
|
2007-11-30 |
2016-04-29 |
Глаксо Груп Лимитед |
Антиген-связывающая конструкция и ее применение
|
|
SG10201408165WA
(en)
|
2007-12-11 |
2015-01-29 |
Scripps Research Inst |
Compositions and methods related to mrna translational enhancer elements
|
|
WO2009120247A2
(en)
|
2007-12-27 |
2009-10-01 |
The Ohio State University Research Foundation |
Lipid nanoparticle compositions and methods of making and using the same
|
|
HRP20150528T2
(hr)
|
2008-01-31 |
2016-03-25 |
Curevac Gmbh |
NUKLEINSKE KISELINE KOJE SADRŽE FORMULU (NuGiXmGnNv)a TE NJIHOVI DERIVATI KAO IMUNOSTIMULACIJSKA SREDSTVA/POMOĆNA SREDSTVA
|
|
WO2009100430A2
(en)
|
2008-02-08 |
2009-08-13 |
Asuragen, Inc |
miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
|
|
CN102015027A
(zh)
|
2008-02-28 |
2011-04-13 |
俄亥俄州立大学研究基金会 |
与人慢性淋巴细胞性白血病(ccl)相关的微rna特征和其用途
|
|
JP5475753B2
(ja)
*
|
2008-04-15 |
2014-04-16 |
プロチバ バイオセラピューティクス インコーポレイティッド |
核酸送達用の脂質製剤
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
EP2112235A1
(en)
|
2008-04-24 |
2009-10-28 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for microRNA expression profiling of nasopharyngeal carcinoma
|
|
WO2009131704A2
(en)
|
2008-04-25 |
2009-10-29 |
Northwestern University |
Nanostructures suitable for sequestering cholesterol and other molecules
|
|
US8697098B2
(en)
|
2011-02-25 |
2014-04-15 |
South Dakota State University |
Polymer conjugated protein micelles
|
|
CA3065577C
(en)
|
2008-05-13 |
2022-05-31 |
Phaserx, Inc. |
Diblock copolymers and polynucleotide complexes thereof for delivery into cells
|
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
|
TWI451876B
(zh)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
|
EP2309990B2
(en)
|
2008-06-16 |
2017-03-15 |
Pfizer Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
|
WO2010018563A2
(en)
|
2008-08-12 |
2010-02-18 |
Rosetta Genomics Ltd. |
Compositions and methods for the prognosis of lymphoma
|
|
US20120021519A1
(en)
|
2008-09-19 |
2012-01-26 |
Presidents And Fellows Of Harvard College |
Efficient induction of pluripotent stem cells using small molecule compounds
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
EP3225621A1
(en)
|
2008-10-09 |
2017-10-04 |
Arbutus Biopharma Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
|
WO2010045512A2
(en)
|
2008-10-16 |
2010-04-22 |
Mdrna , Inc. |
Processes and compositions for liposomal and efficient delivery of gene silencing therapeutics
|
|
CN104910025B
(zh)
|
2008-11-07 |
2019-07-16 |
麻省理工学院 |
氨基醇类脂质和其用途
|
|
MX338780B
(es)
|
2008-11-10 |
2016-05-02 |
Alnylam Pharmaceuticals Inc |
Lipidos y composiciones novedosas para el suministro de terapeuticos.
|
|
CA2780482A1
(en)
|
2008-11-17 |
2010-05-10 |
Anil K. Sood |
Hdl particles for delivery of nucleic acids
|
|
WO2010066384A1
(en)
|
2008-12-10 |
2010-06-17 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for micro-rna expression profiling of cancer stem cells
|
|
US8563041B2
(en)
|
2008-12-12 |
2013-10-22 |
Bind Therapeutics, Inc. |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
|
EP3243504A1
(en)
|
2009-01-29 |
2017-11-15 |
Arbutus Biopharma Corporation |
Improved lipid formulation
|
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
|
CA2754043A1
(en)
|
2009-03-12 |
2010-09-16 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes
|
|
CN102438978B
(zh)
|
2009-03-20 |
2017-02-22 |
Clsn实验室股份有限公司 |
聚胺衍生物
|
|
US20120095077A1
(en)
|
2009-03-23 |
2012-04-19 |
University Of Utah Research Foundation |
Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference
|
|
EP3097908A1
(en)
|
2009-05-05 |
2016-11-30 |
Arbutus Biopharma Corporation |
Lipid compositions
|
|
US20120264626A1
(en)
|
2009-05-08 |
2012-10-18 |
The Ohio State University Research Foundation |
MicroRNA Expression Profiling and Targeting in Chronic Obstructive Pulmonary Disease (COPD) Lung Tissue and Methods of Use Thereof
|
|
PL2440183T3
(pl)
|
2009-06-10 |
2019-01-31 |
Arbutus Biopharma Corporation |
Ulepszona formulacja lipidowa
|
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
|
CA2767127A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for delivery of therapeutic agents to solid tumors
|
|
US9937128B2
(en)
*
|
2009-08-03 |
2018-04-10 |
The University Of North Carolina At Chapel Hill |
Liposomes comprising a calcium phosphate-containing precipitate
|
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
|
EP2496700B1
(en)
|
2009-11-04 |
2017-03-01 |
The University Of British Columbia |
Nucleic acid-containing lipid particles and related methods
|
|
WO2011062965A2
(en)
|
2009-11-18 |
2011-05-26 |
University Of Washington Through Its Center For Commercialization |
Targeting monomers and polymers having targeting blocks
|
|
EP3318248B1
(en)
|
2009-12-01 |
2019-04-10 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
BR112012013875B8
(pt)
|
2009-12-07 |
2020-06-23 |
Person Anthony |
método in vitro para reprogramar células somáticas humanas ou de outros mamíferos para células tronco pluripotentes induzidas (células ips ou ipscs) e composição
|
|
EP3296398A1
(en)
|
2009-12-07 |
2018-03-21 |
Arbutus Biopharma Corporation |
Compositions for nucleic acid delivery
|
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
|
EP2509634B1
(en)
|
2009-12-11 |
2019-03-06 |
Pfizer Inc |
Stable formulations for lyophilizing therapeutic particles
|
|
US20110144544A1
(en)
|
2009-12-15 |
2011-06-16 |
General Electric Company |
Ultrasound transducer assembly and methods of using
|
|
EP3494963A1
(en)
|
2009-12-18 |
2019-06-12 |
The University of British Columbia |
Methods and compositions for delivery of nucleic acids
|
|
WO2011076807A2
(en)
|
2009-12-23 |
2011-06-30 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
|
WO2011076143A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expression profiling of lung cancer
|
|
WO2011076142A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expession profiling in plasma of colorectal cancer
|
|
EP2341145A1
(en)
|
2009-12-30 |
2011-07-06 |
febit holding GmbH |
miRNA fingerprint in the diagnosis of diseases
|
|
WO2011094683A2
(en)
|
2010-01-29 |
2011-08-04 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Method of identifying myelodysplastic syndromes
|
|
EP2354246A1
(en)
|
2010-02-05 |
2011-08-10 |
febit holding GmbH |
miRNA in the diagnosis of ovarian cancer
|
|
US20130059015A1
(en)
|
2010-03-11 |
2013-03-07 |
H. Lee Moffitt Cancer Center & Research Institute |
Human Cancer micro-RNA Expression Profiles Predictive of Chemo-Response
|
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
|
WO2011119058A2
(en)
*
|
2010-03-22 |
2011-09-29 |
Universidade De Coimbra |
F3-peptide targeted lipid-based nanoparticles useful for the treatment of angiogenesis-dependent diseases
|
|
US8349308B2
(en)
|
2010-03-26 |
2013-01-08 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
|
EP2558074B1
(en)
|
2010-04-08 |
2018-06-06 |
The Trustees of Princeton University |
Preparation of lipid nanoparticles
|
|
EP2572706A4
(en)
*
|
2010-04-21 |
2014-02-26 |
Univ Hokkaido Nat Univ Corp |
Lipid membrane structure with nucleic acid transportability
|
|
WO2011139911A2
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
|
WO2011143230A1
(en)
|
2010-05-10 |
2011-11-17 |
Alnylam Pharmaceuticals |
Methods and compositions for delivery of active agents
|
|
EP2569276B1
(en)
|
2010-05-12 |
2021-02-24 |
Arbutus Biopharma Corporation |
Novel cationic lipids and methods of use thereof
|
|
WO2011141704A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc |
Novel cyclic cationic lipids and methods of use
|
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
|
US8748667B2
(en)
|
2010-06-04 |
2014-06-10 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
|
WO2011157294A1
(en)
|
2010-06-16 |
2011-12-22 |
Universita' Degli Studi Di Padova |
Compositions for use in treating or preventing cancer, breast cancer, lung cancer, ovarian cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto
|
|
US20130236968A1
(en)
|
2010-06-21 |
2013-09-12 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
|
CA2804396C
(en)
|
2010-07-06 |
2021-06-29 |
Novartis Ag |
Liposomes with lipids having an advantageous pka-value for rna delivery
|
|
US11291635B2
(en)
|
2010-07-06 |
2022-04-05 |
Glaxosmithkline Biological Sa |
Virion-like delivery particles for self-replicating RNA molecules
|
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
US20130230884A1
(en)
|
2010-07-16 |
2013-09-05 |
John Chaput |
Methods to Identify Synthetic and Natural RNA Elements that Enhance Protein Translation
|
|
EP2449113B8
(en)
|
2010-07-30 |
2015-11-25 |
CureVac AG |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
|
RS63890B1
(sr)
|
2010-08-31 |
2023-02-28 |
Glaxosmithkline Biologicals Sa |
Mali lipozomi za isporuku rnk koja kodira imunogen
|
|
SI3981427T1
(sl)
|
2010-08-31 |
2022-08-31 |
Glaxosmithkline Biologicals S.A. |
Pegilirani liposomi za dostavo imunogen-kodirajoče RNA
|
|
US20130189351A1
(en)
|
2010-08-31 |
2013-07-25 |
Novartis Ag |
Lipids suitable for liposomal delivery of protein coding rna
|
|
US10307372B2
(en)
|
2010-09-10 |
2019-06-04 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
|
ES2888231T3
(es)
|
2010-09-20 |
2022-01-03 |
Sirna Therapeutics Inc |
Lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos
|
|
EP2621480B1
(en)
|
2010-09-30 |
2018-08-15 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
|
ES3005233T3
(en)
|
2010-10-01 |
2025-03-14 |
Modernatx Inc |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
EP3485913A1
(en)
|
2010-10-21 |
2019-05-22 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
|
US10364440B2
(en)
|
2011-01-04 |
2019-07-30 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
|
AU2012207606B2
(en)
|
2011-01-11 |
2017-02-23 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
|
CN102068701B
(zh)
|
2011-01-18 |
2012-11-07 |
沈阳药科大学 |
可断裂peg脂质衍生物在制剂中的应用
|
|
US10363309B2
(en)
|
2011-02-04 |
2019-07-30 |
Case Western Reserve University |
Targeted nanoparticle conjugates
|
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
|
AU2012217685B2
(en)
|
2011-02-15 |
2017-05-18 |
Merrimack Pharmaceuticals, Inc. |
Compositions and methods for delivering nucleic acid to a cell
|
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
|
CN102204920B
(zh)
|
2011-03-18 |
2013-03-20 |
海南本创医药科技有限公司 |
阿司匹林钠普伐他汀钠药物组合物固体制剂
|
|
ES2785108T3
(es)
|
2011-03-24 |
2020-10-05 |
Glaxosmithkline Biologicals Sa |
Nanoemulsiones adyuvantes con fosfolípidos
|
|
CA2831392C
(en)
|
2011-03-28 |
2020-04-28 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
|
WO2013158127A1
(en)
|
2012-04-16 |
2013-10-24 |
Molecular Transfer, Inc. |
Agents for improved delivery of nucleic acids to eukaryotic cells
|
|
EP2701686A4
(en)
|
2011-04-28 |
2014-11-05 |
Stc Unm |
LIPID BINCHES SUPPORTED ON POROUS NANOPARTICLES (PROTOCELLS) FOR TARGETED ADMINISTRATION, AND METHODS OF USE THEREOF
|
|
US9364433B2
(en)
|
2011-04-28 |
2016-06-14 |
Borje S. Andersson |
Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
|
|
CN104623666A
(zh)
|
2011-04-29 |
2015-05-20 |
西莱克塔生物科技公司 |
用于诱导调节性b细胞的致耐受性合成纳米载体
|
|
US20140113978A1
(en)
|
2011-05-01 |
2014-04-24 |
University Of Rochester |
Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof
|
|
EP2944961A1
(en)
|
2011-05-06 |
2015-11-18 |
XenTech |
Markers for cancer prognosis and therapy and methods of use
|
|
CN103687624B
(zh)
|
2011-05-11 |
2018-02-02 |
雷蒙特亚特特拉维夫大学有限公司 |
靶向的聚合缀合物和其用途
|
|
US20140072657A1
(en)
|
2011-05-12 |
2014-03-13 |
Helmut Vockner |
Novel pharmaceutical formulation
|
|
AU2012254842A1
(en)
|
2011-05-12 |
2013-05-02 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Liposomes comprising polymer-conjugated lipids and related uses
|
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
|
US20140206752A1
(en)
|
2011-05-17 |
2014-07-24 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof for non-human vertebrates
|
|
WO2012159643A1
(en)
|
2011-05-24 |
2012-11-29 |
Biontech Ag |
Individualized vaccines for cancer
|
|
CN107115314B
(zh)
|
2011-06-02 |
2022-04-29 |
加利福尼亚大学董事会 |
膜包封的纳米颗粒及使用方法
|
|
CN103608683A
(zh)
|
2011-06-02 |
2014-02-26 |
诺华股份有限公司 |
Hedgehog抑制剂治疗的生物标志物
|
|
EP2717893B1
(en)
|
2011-06-08 |
2019-05-08 |
Translate Bio, Inc. |
Lipid nanoparticle compositions and methods for mrna delivery
|
|
ES2570184T3
(es)
|
2011-06-08 |
2016-05-17 |
Nitto Denko Corp |
Compuestos para dirigir la administración de fármacos y potenciar la actividad de ARNip
|
|
CA3198966A1
(en)
|
2011-06-08 |
2012-12-13 |
Translate Bio, Inc. |
Cleavable lipids
|
|
CN102813929B
(zh)
|
2011-06-09 |
2014-04-09 |
沈阳药科大学 |
低浓度peg脂质衍生物及其应用
|
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
|
EP3854413A1
(en)
|
2011-07-06 |
2021-07-28 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
|
CA2840965C
(en)
|
2011-07-06 |
2021-03-02 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
EP3424495A1
(en)
|
2011-07-06 |
2019-01-09 |
GlaxoSmithKline Biologicals S.A. |
Oil-in-water emulsions that contain nucleic acids
|
|
BR112014000236A2
(pt)
|
2011-07-06 |
2017-02-14 |
Novartis Ag |
lipossomas com razão n:p útil para a liberação de moléculas de rna, composição e uso de ditos lipossomas
|
|
EP2729168A2
(en)
|
2011-07-06 |
2014-05-14 |
Novartis AG |
Immunogenic compositions and uses thereof
|
|
ES2610245T3
(es)
|
2011-07-15 |
2017-04-26 |
Leo Pharma A/S |
Perfilado de microARN para el diagnóstico en linfoma cutáneo de células T (CTCL)
|
|
CN103732211B
(zh)
|
2011-07-21 |
2017-03-01 |
禾大国际股份公开有限公司 |
支化的聚醚‑聚酰胺嵌段共聚物及其制造与使用方法
|
|
HK1199736A1
(en)
|
2011-08-26 |
2015-07-17 |
箭头研究公司 |
Poly(vinyl ester) polymers for in vivo nucleic acid delivery
|
|
US8889657B2
(en)
|
2011-08-31 |
2014-11-18 |
Mallinckrodt Llc |
Nanoparticle PEG modification with H-phosphonates
|
|
HUE041800T2
(hu)
*
|
2011-08-31 |
2019-05-28 |
Glaxosmithkline Biologicals Sa |
Pegilált liposzómák immunogént kódoló RNS bejuttatására
|
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
|
EP2751292A4
(en)
|
2011-09-01 |
2015-05-20 |
Allegro Diagnostics Corp |
METHOD AND COMPOSITIONS FOR DETECTING CANCER BASED ON MIRNA EXPRESSION PROFILES
|
|
AU2012301675A1
(en)
|
2011-09-01 |
2014-03-13 |
Irm Llc |
Compounds and compositions as PDGFR kinase inhibitors
|
|
EP3384938A1
(en)
|
2011-09-12 |
2018-10-10 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US9375388B2
(en)
|
2011-09-23 |
2016-06-28 |
Indian Institute Of Technology, Bombay |
Nanoparticle based cosmetic composition
|
|
WO2013049328A1
(en)
|
2011-09-27 |
2013-04-04 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
|
WO2014066811A1
(en)
|
2012-10-25 |
2014-05-01 |
The Johns Hopkins University |
Bioreducible poly (b-amino ester)s for sirna delivery
|
|
BR112014008932A2
(pt)
|
2011-10-14 |
2019-09-24 |
Sandia Corp |
bicamadas lipídicas suportadas em nanopartículas porosas (protocélulas) para administração direcionada, incluindo a administração transdérmica de uma carga e métodos associados
|
|
DK2768958T3
(da)
|
2011-10-18 |
2019-09-16 |
Dicerna Pharmaceuticals Inc |
Kationiske aminlipider og anvendelser deraf
|
|
CA2852857A1
(en)
|
2011-10-20 |
2013-04-25 |
Novartis Ag |
Adjuvanted influenza b virus vaccines for pediatric priming
|
|
JP2015502337A
(ja)
|
2011-10-25 |
2015-01-22 |
ザ ユニバーシティ オブ ブリティッシュ コロンビア |
限界サイズ脂質ナノ粒子および関連方法
|
|
WO2013066678A1
(en)
|
2011-10-26 |
2013-05-10 |
Georgetown University |
Microrna expression profiling of thyroid cancer
|
|
WO2013063468A1
(en)
|
2011-10-27 |
2013-05-02 |
Massachusetts Institute Of Technology |
Amino acid derivates functionalized on the n- terminal capable of forming drug incapsulating microspheres
|
|
CA2852564A1
(en)
|
2011-10-31 |
2013-05-10 |
Mallinckrodt Llc |
Combinational liposome compositions for cancer therapy
|
|
WO2013066274A1
(en)
|
2011-11-04 |
2013-05-10 |
Agency For Science, Technology And Research |
Self-assembled composite ultrasmall peptide-polymer hydrogels
|
|
US9579338B2
(en)
|
2011-11-04 |
2017-02-28 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
|
US9872870B2
(en)
|
2011-11-04 |
2018-01-23 |
University Of Notre Dame Du Lac |
Multifunctional micellar nanoparticle-based drug and targeting agent system
|
|
EP3673898A1
(en)
|
2011-11-04 |
2020-07-01 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
|
EP2776013B8
(en)
|
2011-11-08 |
2023-08-30 |
The Board of Trustees of the University of Arkansas |
Methods and compositions for x-ray induced release from ph sensitive liposomes
|
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
|
EP2788006A1
(en)
|
2011-12-07 |
2014-10-15 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
|
WO2013086373A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
|
CA2856737C
(en)
|
2011-12-07 |
2023-09-26 |
Alnylam Pharmaceuticals, Inc. |
Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents
|
|
EP2787977A4
(en)
|
2011-12-09 |
2015-05-06 |
Univ California |
LIPOSOMAL ACTIVE INVERTING
|
|
CN104159615B
(zh)
|
2011-12-12 |
2017-08-18 |
协和发酵麒麟株式会社 |
含有阳离子性脂质的组合的脂质纳米粒子
|
|
TWI594767B
(zh)
|
2011-12-12 |
2017-08-11 |
協和醱酵麒麟有限公司 |
含有陽離子性脂質之藥物傳遞系統用脂質奈米粒子
|
|
EP2604253A1
(en)
|
2011-12-13 |
2013-06-19 |
Otto Glatter |
Water-in-oil emulsions and methods for their preparation
|
|
US20140378538A1
(en)
|
2011-12-14 |
2014-12-25 |
Moderma Therapeutics, Inc. |
Methods of responding to a biothreat
|
|
US9636414B2
(en)
|
2011-12-15 |
2017-05-02 |
Biontech Ag |
Particles comprising single stranded RNA and double stranded RNA for immunomodulation
|
|
AU2012352180A1
(en)
|
2011-12-16 |
2014-07-31 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
|
WO2013096709A2
(en)
|
2011-12-21 |
2013-06-27 |
modeRNA Therapeutics |
Methods of increasing the viability or longevity of an organ or organ explant
|
|
LT3144389T
(lt)
|
2011-12-30 |
2018-08-10 |
Cellscript, Llc |
In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį
|
|
WO2013103659A1
(en)
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
|
EP2807251B1
(en)
|
2012-01-26 |
2018-01-10 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
|
AU2013212068B2
(en)
|
2012-01-26 |
2018-02-15 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
|
WO2013120497A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
|
|
WO2013120499A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
|
|
WO2013120500A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigen
|
|
WO2013120498A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded allergenic antigen or an autoimmune self-antigen
|
|
HK1205751A1
(en)
|
2012-02-22 |
2015-12-24 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
|
AU2013222179B2
(en)
|
2012-02-24 |
2017-08-24 |
Arbutus Biopharma Corporat ion |
Trialkyl cationic lipids and methods of use thereof
|
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
|
JP5883539B2
(ja)
|
2012-03-16 |
2016-03-15 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
Ｈｉｆ−１阻害剤の送達のための放出制御製剤
|
|
CA2867203C
(en)
|
2012-03-16 |
2016-09-20 |
The Johns Hopkins University |
Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
|
|
DK2825156T3
(en)
|
2012-03-16 |
2017-10-30 |
Merck Patent Gmbh |
TARGETED AMINO ACID LIPIDS
|
|
EP2830991A1
(en)
|
2012-03-26 |
2015-02-04 |
President and Fellows of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
DK2830594T3
(en)
|
2012-03-27 |
2018-08-13 |
Sirna Therapeutics Inc |
DIETHER-BASED BIOLOGICALLY DEGRADABLE CATIONIC LIPIDS FOR siRNA RELEASE
|
|
RU2660565C2
(ru)
|
2012-03-27 |
2018-07-06 |
Кьюрвак Аг |
Молекулы искусственной нуклеиновой кислоты, содержащие 5'utr гена top
|
|
RU2750261C2
(ru)
|
2012-03-27 |
2021-06-25 |
Кьюрвак Аг |
Искусственные молекулы нуклеиновых кислот для улучшенной экспрессии белков и пептидов
|
|
EP2831239B1
(en)
|
2012-03-27 |
2017-11-22 |
CureVac AG |
Artificial nucleic acid molecules
|
|
HK1206644A1
(en)
|
2012-03-29 |
2016-01-15 |
Shire Human Genetic Therapies, Inc. |
Lipid-derived neutral nanoparticles
|
|
AU2013243949A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
WO2013151663A1
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
US10501513B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides for the production of oncology-related proteins and peptides
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US20150064115A1
(en)
|
2012-04-05 |
2015-03-05 |
University Of Florida Research Foundation, Inc. |
Neurophilic nanoparticles
|
|
JP2015514132A
(ja)
|
2012-04-10 |
2015-05-18 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
ヒト呼吸器合胞体ウイルスコンセンサス抗原、核酸構築物、およびそれらから作製されるワクチン、ならびにその使用方法
|
|
US9078930B2
(en)
|
2012-04-11 |
2015-07-14 |
Intezyne Technologies, Inc. |
Block copolymers for stable micelles
|
|
EP2836234B1
(en)
|
2012-04-12 |
2019-06-12 |
Yale University |
Vehicles for controlled delivery of different pharmaceutical agents
|
|
CA2870941C
(en)
|
2012-04-19 |
2021-05-25 |
Sirna Therapeutics, Inc. |
Diester and triester based low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
|
WO2013166498A1
(en)
|
2012-05-04 |
2013-11-07 |
The Johns Hopkins University |
Lipid-based drug carriers for rapid penetration through mucus linings
|
|
WO2013173693A1
(en)
|
2012-05-18 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanoparticles with enhanced entry into cancer cells
|
|
CA2874495A1
(en)
|
2012-05-23 |
2013-11-28 |
The Ohio State University |
Lipid-coated albumin nanoparticle compositions and methods of making and methods of using the same
|
|
US20150306249A1
(en)
|
2012-05-25 |
2015-10-29 |
Curevac Gmbh |
Reversible immobilization and/or controlled release of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
|
|
WO2013185069A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
|
CA2876148C
(en)
|
2012-06-08 |
2021-01-12 |
Nitto Denko Corporation |
Lipids for therapeutic agent delivery formulations
|
|
US9415109B2
(en)
|
2012-07-06 |
2016-08-16 |
Alnylam Pharmaceuticals, Inc. |
Stable non-aggregating nucleic acid lipid particle formulations
|
|
US9931418B2
(en)
|
2012-08-07 |
2018-04-03 |
Northeastern University |
Compositions for the delivery of RNA and drugs into cells
|
|
WO2014024193A1
(en)
|
2012-08-07 |
2014-02-13 |
Prodel Pharma Ltd. |
Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
|
|
CA2884870C
(en)
*
|
2012-08-13 |
2022-03-29 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
|
EP2885419A4
(en)
|
2012-08-14 |
2016-05-25 |
Moderna Therapeutics Inc |
ENZYMES AND POLYMERASES FOR RNA SYNTHESIS
|
|
US9775804B2
(en)
|
2012-08-14 |
2017-10-03 |
Aaron Froese |
Internal structured self assembling liposomes
|
|
WO2014028763A1
(en)
|
2012-08-15 |
2014-02-20 |
The University Of Chicago |
Exosome-based therapeutics against neurodegenerative disorders
|
|
US8703197B2
(en)
|
2012-09-13 |
2014-04-22 |
International Business Machines Corporation |
Branched polyamines for delivery of biologically active materials
|
|
EA032943B1
(ru)
|
2012-09-17 |
2019-08-30 |
Пфайзер Инк. |
Способ получения терапевтических наночастиц (варианты) и терапевтическая наночастица (варианты)
|
|
WO2014047649A1
(en)
|
2012-09-24 |
2014-03-27 |
The Regents Of The University Of California |
Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
|
|
US20150246137A1
(en)
|
2012-09-27 |
2015-09-03 |
The University Of North Carolina At Chapel Hill |
Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof
|
|
WO2014053882A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
WO2014053879A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
EP2903595A1
(en)
|
2012-10-04 |
2015-08-12 |
University Of The Witwatersrand, Johannesburg |
Liposomal drug delivery system
|
|
WO2014053880A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
WO2014053881A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
KR20150070318A
(ko)
|
2012-10-16 |
2015-06-24 |
엔도사이트, 인코포레이티드 |
비천연 아미노산을 함유하는 약물 전달 컨쥬게이트 및 사용 방법
|
|
CN104918639B
(zh)
|
2012-10-22 |
2018-01-26 |
萨拜格Rfa公司 |
用于将治疗剂递送到活细胞和细胞核中的系统
|
|
JP2016503394A
(ja)
|
2012-10-26 |
2016-02-04 |
エヌライフ、セラピューティックス、ソシエダッド、リミターダＮｌｉｆｅ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｓ．Ｌ． |
細胞型へのオリゴヌクレオチド分子の選択的送達のための組成物および方法
|
|
US20150272900A1
(en)
|
2012-10-26 |
2015-10-01 |
The Johns Hopkins University |
Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics
|
|
WO2014071072A2
(en)
|
2012-11-02 |
2014-05-08 |
Pungente Michael D |
Novel cationic carotenoid-based lipids for cellular nucleic acid uptake
|
|
WO2014074289A1
(en)
|
2012-11-06 |
2014-05-15 |
Rochal Industries, Llp |
Delivery of biologically-active agents using volatile, hydrophobic solvents
|
|
US9669104B2
(en)
|
2012-11-07 |
2017-06-06 |
Council Of Scientific And Industrial Research |
Nanocomplex containing amphipathic peptide useful for efficient transfection of biomolecules
|
|
BR112015010566A2
(pt)
|
2012-11-08 |
2017-07-11 |
Clearside Biomedical Inc |
métodos e dispositivos para o tratamento de doenças oculares em indivíduos humanos
|
|
WO2014072468A1
(en)
|
2012-11-09 |
2014-05-15 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
|
US9200119B2
(en)
|
2012-11-09 |
2015-12-01 |
Momentive Performance Materials Inc. |
Silicon-containing zwitterionic linear copolymer composition
|
|
JP2016500058A
(ja)
|
2012-11-12 |
2016-01-07 |
レッドウッド バイオサイエンス， インコーポレイテッド |
化合物および抱合体を生成するための方法
|
|
WO2014078399A1
(en)
|
2012-11-13 |
2014-05-22 |
Baylor College Of Medicine |
Multi-arm biodegradable polymers for nucleic acid delivery
|
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
|
WO2014081849A1
(en)
|
2012-11-20 |
2014-05-30 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
|
FI2922574T3
(fi)
|
2012-11-22 |
2023-08-11 |
Tagworks Pharmaceuticals B V |
Kemiallisesti pilkkoutuva ryhmä
|
|
WO2014081299A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Activatable liposomes
|
|
WO2014081300A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Channel protein activatable liposomes
|
|
HRP20220607T1
(hr)
|
2012-11-26 |
2022-06-24 |
Modernatx, Inc. |
Terminalno modificirana rna
|
|
US9687448B2
(en)
|
2012-12-07 |
2017-06-27 |
Alnylam Pharmaceuticals, Inc. |
Nucleic acid lipid particle formulations
|
|
ES2968649T3
(es)
|
2012-12-07 |
2024-05-13 |
Translate Bio Inc |
Nanopartículas lipídicas para la administración de ARNm en los pulmones
|
|
EP2931914A4
(en)
|
2012-12-13 |
2016-08-17 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES FOR CHANGING THE CELL PHENOTYPE
|
|
EP2931319B1
(en)
|
2012-12-13 |
2019-08-21 |
ModernaTX, Inc. |
Modified nucleic acid molecules and uses thereof
|
|
CA2897752A1
(en)
|
2013-01-10 |
2014-07-17 |
Novartis Ag |
Influenza virus immunogenic compositions and uses thereof
|
|
EP2946014A2
(en)
|
2013-01-17 |
2015-11-25 |
Moderna Therapeutics, Inc. |
Signal-sensor polynucleotides for the alteration of cellular phenotypes
|
|
SG10201710472PA
(en)
|
2013-02-22 |
2018-02-27 |
Curevac Ag |
Combination of vaccination and inhibition of the pd-1 pathway
|
|
EP2968391A1
(en)
|
2013-03-13 |
2016-01-20 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
|
EP2971010B1
(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
TR201901310T4
(tr)
|
2013-03-14 |
2019-02-21 |
Translate Bio Inc |
Mesajcı RNA'nın saflaştırılması yöntemleri.
|
|
CA2906110C
(en)
|
2013-03-14 |
2021-07-27 |
Dicerna Pharmaceuticals, Inc. |
Process for formulating an anionic agent
|
|
WO2014160243A1
(en)
|
2013-03-14 |
2014-10-02 |
The Trustees Of The University Of Pennsylvania |
Purification and purity assessment of rna molecules synthesized with modified nucleosides
|
|
US9693958B2
(en)
|
2013-03-15 |
2017-07-04 |
Cureport, Inc. |
Methods and devices for preparation of lipid nanoparticles
|
|
CA2906732C
(en)
|
2013-03-15 |
2023-08-08 |
The University Of British Columbia |
Lipid nanoparticles for transfection and related methods
|
|
US10590161B2
(en)
|
2013-03-15 |
2020-03-17 |
Modernatx, Inc. |
Ion exchange purification of mRNA
|
|
DK2972360T3
(en)
|
2013-03-15 |
2018-05-22 |
Translate Bio Inc |
SYNERGISTIC IMPROVEMENT OF DELIVERY OF NUCLEIC ACIDS THROUGH MIXED FORMULATIONS
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
US10138507B2
(en)
|
2013-03-15 |
2018-11-27 |
Modernatx, Inc. |
Manufacturing methods for production of RNA transcripts
|
|
WO2014144039A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Characterization of mrna molecules
|
|
CN105283548A
(zh)
|
2013-03-15 |
2016-01-27 |
葛兰素史密斯克莱生物公司 |
Rna纯化方法
|
|
EP4279610A3
(en)
|
2013-03-15 |
2024-01-03 |
ModernaTX, Inc. |
Ribonucleic acid purification
|
|
US9593139B2
(en)
*
|
2013-04-05 |
2017-03-14 |
Massachusetts Institute Of Technology |
Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety
|
|
CN118750591A
(zh)
|
2013-04-07 |
2024-10-11 |
博德研究所 |
用于个性化瘤形成疫苗的组合物和方法
|
|
TW201515650A
(zh)
|
2013-05-06 |
2015-05-01 |
艾爾妮蘭製藥公司 |
遞送經脂質調配之核酸分子之劑量及方法
|
|
US9895443B2
(en)
|
2013-06-26 |
2018-02-20 |
Massachusetts Institute Of Technology |
Multi-tailed lipids and uses thereof
|
|
WO2015002667A1
(en)
|
2013-07-01 |
2015-01-08 |
Myq, Inc. |
A location regulated point-of-sale system and enhancements
|
|
TW201534578A
(zh)
|
2013-07-08 |
2015-09-16 |
Daiichi Sankyo Co Ltd |
新穎脂質
|
|
SI3019619T1
(sl)
|
2013-07-11 |
2021-12-31 |
Modernatx, Inc. |
Sestave, ki zajemajo sintetične polinukleotide, ki kodirajo proteine, pozvezane s crispr, in sintetične sgrna, ter metode uporabe
|
|
WO2015011633A1
(en)
|
2013-07-23 |
2015-01-29 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for delivering messenger rna
|
|
JP6685903B2
(ja)
|
2013-07-25 |
2020-04-22 |
アバター・メディカル・エルエルシー |
立体構造的に安定化されたｒｓｖ融合前ｆタンパク質
|
|
US10398769B2
(en)
|
2013-08-06 |
2019-09-03 |
The Trustees Of The University Of Pennsylvania |
Influenza nucleic acid molecules and vaccines made therefrom
|
|
CN105473157A
(zh)
|
2013-08-21 |
2016-04-06 |
库瑞瓦格股份公司 |
组合疫苗
|
|
WO2015024667A1
(en)
|
2013-08-21 |
2015-02-26 |
Curevac Gmbh |
Method for increasing expression of rna-encoded proteins
|
|
WO2015024666A1
(en)
|
2013-08-21 |
2015-02-26 |
Curevac Gmbh |
Composition and vaccine for treating lung cancer
|
|
CA2915728A1
(en)
|
2013-08-21 |
2015-02-26 |
Thomas Kramps |
Respiratory syncytial virus (rsv) vaccine
|
|
MX2016002153A
(es)
|
2013-08-21 |
2017-03-01 |
Curevac Ag |
Composicion y vacuna para tratar cancer de prostata.
|
|
RU2712743C2
(ru)
|
2013-08-21 |
2020-01-30 |
Куревак Аг |
Вакцина против бешенства
|
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3052511A4
(en)
|
2013-10-02 |
2017-05-31 |
Moderna Therapeutics, Inc. |
Polynucleotide molecules and uses thereof
|
|
KR20160067219A
(ko)
|
2013-10-03 |
2016-06-13 |
모더나 세라퓨틱스, 인코포레이티드 |
저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
|
|
AU2014337156A1
(en)
|
2013-10-18 |
2016-05-12 |
Modernatx, Inc. |
Compositions and methods for tolerizing cellular systems
|
|
EP3574923A1
(en)
|
2013-10-22 |
2019-12-04 |
Translate Bio, Inc. |
Mrna therapy for phenylketonuria
|
|
CN105658800A
(zh)
|
2013-10-22 |
2016-06-08 |
夏尔人类遗传性治疗公司 |
Mrna的cns递送及其用途
|
|
CA2925021C
(en)
|
2013-11-01 |
2025-05-06 |
Curevac Ag |
MODIFIED MESSENGER RIBONUCLE ACID (MRNA) WITH REDUCED IMMUNOSTIMULATING PROPERTIES
|
|
CA2932626A1
(en)
*
|
2013-12-05 |
2015-06-11 |
Silence Therapeutics Gmbh |
Means for lung specific delivery
|
|
EP3083556B1
(en)
*
|
2013-12-19 |
2019-12-25 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
|
EP4019506A1
(en)
|
2013-12-19 |
2022-06-29 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
|
US20160367638A1
(en)
|
2013-12-19 |
2016-12-22 |
Crystal BYERS |
LEPTIN mRNA COMPOSITIONS AND FORMULATIONS
|
|
WO2015101416A1
(en)
|
2013-12-30 |
2015-07-09 |
Curevac Gmbh |
Methods for rna analysis
|
|
AU2014375402B2
(en)
|
2013-12-30 |
2020-10-01 |
CureVac SE |
Artificial nucleic acid molecules
|
|
JP6584414B2
(ja)
|
2013-12-30 |
2019-10-02 |
キュアバック アーゲー |
人工核酸分子
|
|
CN112870163A
(zh)
|
2014-01-21 |
2021-06-01 |
安杰瑞姆生物科学公司 |
杂交体、包含该杂交体的组合物、它们的制备方法及用途
|
|
WO2015130584A2
(en)
|
2014-02-25 |
2015-09-03 |
Merck Sharp & Dohme Corp. |
Lipid nanoparticle vaccine adjuvants and antigen delivery systems
|
|
MX369776B
(es)
|
2014-03-01 |
2019-11-21 |
Univ Texas |
Vectores recombinantes del virus isfahan.
|
|
US10307472B2
(en)
|
2014-03-12 |
2019-06-04 |
Curevac Ag |
Combination of vaccination and OX40 agonists
|
|
ES3009962T3
(en)
|
2014-04-23 |
2025-03-31 |
Modernatx Inc |
Nucleic acid vaccines
|
|
WO2015196128A2
(en)
|
2014-06-19 |
2015-12-23 |
Moderna Therapeutics, Inc. |
Alternative nucleic acid molecules and uses thereof
|
|
CN106795096B
(zh)
|
2014-06-25 |
2020-05-29 |
爱康泰生治疗公司 |
用于递送核酸的新型脂质和脂质纳米颗粒制剂
|
|
US20170204152A1
(en)
|
2014-07-16 |
2017-07-20 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
AU2015289573A1
(en)
|
2014-07-17 |
2017-02-02 |
Modernatx, Inc |
Terminal modifications of polynucleotides
|
|
ES2969956T3
(es)
|
2014-09-05 |
2024-05-23 |
Novartis Ag |
Lípidos y composiciones lipídicas para el suministro de agentes activos
|
|
CN104644555A
(zh)
|
2014-11-18 |
2015-05-27 |
中国科学院过程工程研究所 |
一种避免加速血液清除现象的长循环脂质体、制备方法及应用
|
|
EP3247363A4
(en)
|
2015-01-21 |
2018-10-03 |
Moderna Therapeutics, Inc. |
Lipid nanoparticle compositions
|
|
JP6623479B2
(ja)
|
2015-02-08 |
2019-12-25 |
トンリ・バイオメディカル・カンパニー・リミテッド |
脂質ナノ粒子及びその使用
|
|
WO2016164762A1
(en)
|
2015-04-08 |
2016-10-13 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
|
|
EP3283059B1
(en)
|
2015-04-13 |
2024-01-03 |
CureVac Manufacturing GmbH |
Method for producing rna compositions
|
|
EP3307305A4
(en)
|
2015-06-10 |
2019-05-22 |
Modernatx, Inc. |
TARGETED ADAPTIVE VACCINES
|
|
HRP20240865T1
(hr)
|
2015-06-29 |
2024-10-11 |
Acuitas Therapeutics Inc. |
Lipidi i formulacije lipidnih nanočestica za isporuku nukleinskih kiselina
|
|
WO2017011773A2
(en)
|
2015-07-15 |
2017-01-19 |
Modernatx, Inc. |
Codon-optimized nucleic acids encoding antibodies
|
|
MA42502A
(fr)
|
2015-07-21 |
2018-05-30 |
Modernatx Inc |
Vaccins contre une maladie infectieuse
|
|
WO2017015457A1
(en)
|
2015-07-21 |
2017-01-26 |
Modernatx, Inc. |
Ebola vaccine
|
|
MA42543A
(fr)
|
2015-07-30 |
2018-06-06 |
Modernatx Inc |
Arn épitope peptidiques concatémériques
|
|
US20190008887A1
(en)
|
2015-07-30 |
2019-01-10 |
ModernaTX Inc. |
Multimeric mrna
|
|
US20180237849A1
(en)
|
2015-08-17 |
2018-08-23 |
Modernatx, Inc. |
Rna mapping/fingerprinting
|
|
WO2017031232A1
(en)
*
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
RU2018105118A
(ru)
|
2015-08-21 |
2019-09-23 |
Пфайзер Инк. |
Терапевтические наночастицы, содержащие терапевтический агент, и способы их получения и применения
|
|
ES2910425T3
(es)
|
2015-09-17 |
2022-05-12 |
Modernatx Inc |
Compuestos y composiciones para la administración intracelular de agentes terapéuticos
|
|
US10849920B2
(en)
|
2015-10-05 |
2020-12-01 |
Modernatx, Inc. |
Methods for therapeutic administration of messenger ribonucleic acid drugs
|
|
WO2017066789A1
(en)
|
2015-10-16 |
2017-04-20 |
Modernatx, Inc. |
Mrna cap analogs with modified sugar
|
|
US20180303929A1
(en)
|
2015-10-22 |
2018-10-25 |
Moderna TX, Inc. |
Herpes simplex virus vaccine
|
|
US20180289792A1
(en)
|
2015-10-22 |
2018-10-11 |
ModernaTX. Inc. |
Sexually transmitted disease vaccines
|
|
CA3002922A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
CN118846026A
(zh)
|
2015-10-22 |
2024-10-29 |
摩登纳特斯有限公司 |
广谱流感病毒疫苗
|
|
MA46317A
(fr)
|
2015-10-22 |
2019-08-07 |
Modernatx Inc |
Vaccin contre le virus respiratoire syncytial
|
|
JP2018532777A
(ja)
|
2015-10-22 |
2018-11-08 |
モデルナティーエックス， インコーポレイテッド |
癌ワクチン
|
|
WO2017070624A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Tropical disease vaccines
|
|
PE20181529A1
(es)
|
2015-10-22 |
2018-09-26 |
Modernatx Inc |
Vacunas de acido nucleico para el virus varicela-zoster (vzv)
|
|
MD3718565T2
(ro)
|
2015-10-22 |
2022-09-30 |
Modernatx Inc |
Vaccinuri împotriva virusului respirator
|
|
AU2016344384A1
(en)
|
2015-10-26 |
2018-05-17 |
Translate Bio Ma, Inc. |
Nanoparticle formulations for delivery of nucleic acid complexes
|
|
AU2016366978B2
(en)
*
|
2015-12-10 |
2022-07-28 |
Modernatx, Inc. |
Compositions and methods for delivery of therapeutic agents
|
|
JP7065036B2
(ja)
|
2015-12-17 |
2022-05-11 |
モダーナティエックス・インコーポレイテッド |
メチルマロニルＣｏＡムターゼをコードするポリヌクレオチド
|
|
SMT202200252T1
(it)
*
|
2015-12-22 |
2022-07-21 |
Modernatx Inc |
Composti e composizioni per il rilascio intracellulare di agenti
|
|
US10465190B1
(en)
|
2015-12-23 |
2019-11-05 |
Modernatx, Inc. |
In vitro transcription methods and constructs
|
|
US20210206818A1
(en)
|
2016-01-22 |
2021-07-08 |
Modernatx, Inc. |
Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
|
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
|
US20190298657A1
(en)
|
2016-05-18 |
2019-10-03 |
Modernatx, Inc. |
Polynucleotides Encoding Acyl-CoA Dehydrogenase, Very Long-Chain for the Treatment of Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
|
|
WO2017201328A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
POLYNUCLEOTIDES ENCODING α-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE
|
|
WO2017201317A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polyribonucleotides containing reduced uracil content and uses thereof
|
|
KR102533456B1
(ko)
|
2016-05-18 |
2023-05-17 |
모더나티엑스, 인크. |
릴랙신을 인코딩하는 폴리뉴클레오타이드
|
|
MA45036A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour la citrine pour le traitement de la citrullinémie de type 2
|
|
MA45053A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour un régulateur de conductance transmembranaire de fibrose kystique pour le traitement de la fibrose kystique
|
|
US12128113B2
(en)
|
2016-05-18 |
2024-10-29 |
Modernatx, Inc. |
Polynucleotides encoding JAGGED1 for the treatment of Alagille syndrome
|
|
JP2019519601A
(ja)
|
2016-05-18 |
2019-07-11 |
モダーナティエックス・インコーポレイテッドＭｏｄｅｒｎａＴＸ， Ｉｎｃ． |
急性間欠性ポルフィリン症の治療のためのポルホビリノゲン脱アミノ酵素をコードするポリヌクレオチド
|
|
WO2017201348A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding galactose-1-phosphate uridylyltransferase for the treatment of galactosemia type 1
|
|
MA45050A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour la lipoprotéine lipase destinés au traitement de l'hyperlipidémie
|
|
JP2019519516A
(ja)
|
2016-05-18 |
2019-07-11 |
モデルナティーエックス， インコーポレイテッド |
がんの治療のためのｍＲＮＡ併用療法
|
|
JP2019525901A
(ja)
*
|
2016-06-14 |
2019-09-12 |
モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． |
脂質ナノ粒子の安定化製剤
|
|
EP3472311A4
(en)
*
|
2016-06-17 |
2020-03-04 |
Montana State University |
BIDIRECTIONAL TARGETING FOR GENOME EDITING
|
|
MX2018016389A
(es)
|
2016-06-30 |
2019-08-16 |
Arbutus Biopharma Corp |
Composiciones y metodos para suministro de arn mensajero.
|
|
EP3500294A4
(en)
*
|
2016-08-22 |
2020-07-29 |
Arbutus Biopharma Corporation |
ANTI-PD-1 ANTIBODIES, OR THEIR FRAGMENTS, FOR THE TREATMENT OF HEPATITIS B
|
|
WO2018053209A1
(en)
|
2016-09-14 |
2018-03-22 |
Modernatx, Inc. |
High purity rna compositions and methods for preparation thereof
|
|
EP3528821A4
(en)
|
2016-10-21 |
2020-07-01 |
ModernaTX, Inc. |
HUMAN CYTOMEGALOVIRUS VACCINE
|
|
MX2019004913A
(es)
|
2016-10-26 |
2019-09-16 |
Curevac Ag |
Vacunas de nanoparticulas lipidicas que comprenden acido ribonucleico mensajero (arnm).
|
|
WO2018081462A1
(en)
|
2016-10-26 |
2018-05-03 |
Modernatx, Inc. |
Methods and compositions for rna mapping
|
|
EP3532103B1
(en)
|
2016-10-26 |
2025-12-03 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
RU2765874C2
(ru)
|
2016-10-26 |
2022-02-04 |
МОДЕРНАТиЭкс, ИНК. |
Матричные рибонуклеиновые кислоты для усиления иммунных ответов и способы их применения
|
|
US11583504B2
(en)
|
2016-11-08 |
2023-02-21 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
|
AU2017357758B2
(en)
|
2016-11-10 |
2023-11-16 |
Translate Bio, Inc. |
Improved process of preparing mRNA-loaded lipid nanoparticles
|
|
KR20190120160A
(ko)
|
2016-11-10 |
2019-10-23 |
트랜슬레이트 바이오 인코포레이티드 |
Mrna의 전달을 위한 개선된 ice계 지질 나노입자 제형
|
|
CN110167587A
(zh)
|
2016-11-11 |
2019-08-23 |
摩登纳特斯有限公司 |
流感疫苗
|
|
US11103578B2
(en)
|
2016-12-08 |
2021-08-31 |
Modernatx, Inc. |
Respiratory virus nucleic acid vaccines
|
|
US11384352B2
(en)
|
2016-12-13 |
2022-07-12 |
Modernatx, Inc. |
RNA affinity purification
|
|
EP3558355A2
(en)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Henipavirus vaccine
|
|
US20180243225A1
(en)
|
2017-01-25 |
2018-08-30 |
Modernatx, Inc. |
Ebola/marburg vaccines
|
|
WO2018144778A1
(en)
|
2017-02-01 |
2018-08-09 |
Modernatx, Inc. |
Polynucleotide secondary structure
|
|
EP3576780A1
(en)
|
2017-02-01 |
2019-12-11 |
Modernatx, Inc. |
Immunomodulatory therapeutic mrna compositions encoding activating oncogene mutation peptides
|
|
KR20190120233A
(ko)
|
2017-02-01 |
2019-10-23 |
모더나티엑스, 인크. |
Rna 암 백신
|
|
WO2018151816A1
(en)
|
2017-02-16 |
2018-08-23 |
Modernatx, Inc. |
High potency immunogenic compositions
|
|
US20200368162A1
(en)
|
2017-02-24 |
2020-11-26 |
Modernatx, Inc. |
Nucleic Acid-Based Therapy of Muscular Dystrophies
|
|
MA47787A
(fr)
|
2017-03-15 |
2020-01-22 |
Modernatx Inc |
Vaccin contre le virus respiratoire syncytial
|
|
US11045540B2
(en)
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
|
SI3596041T1
(sl)
|
2017-03-15 |
2023-02-28 |
Modernatx, Inc. |
Spojina in sestavki za intracelično dostavljanje terapevtskih sredstev
|
|
US11752206B2
(en)
|
2017-03-15 |
2023-09-12 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
|
CA3055653A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Lipid nanoparticle formulation
|
|
EP3609534A4
(en)
|
2017-03-15 |
2021-01-13 |
ModernaTX, Inc. |
WIDE SPECTRUM INFLUENZA VIRUS VACCINE
|
|
EP3595676A4
(en)
|
2017-03-17 |
2021-05-05 |
Modernatx, Inc. |
RNA VACCINES AGAINST ZOONOSES
|
|
US20200038499A1
(en)
|
2017-03-22 |
2020-02-06 |
Modernatx, Inc. |
Rna bacterial vaccines
|
|
MA48047A
(fr)
|
2017-04-05 |
2020-02-12 |
Modernatx Inc |
Réduction ou élimination de réponses immunitaires à des protéines thérapeutiques administrées par voie non intraveineuse, par exemple par voie sous-cutanée
|
|
US20200054737A1
(en)
|
2017-04-26 |
2020-02-20 |
Modema TX, Inc. |
Herpes simplex virus vaccine
|
|
EP3638678B1
(en)
|
2017-06-14 |
2025-12-03 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
WO2018232355A1
(en)
|
2017-06-15 |
2018-12-20 |
Modernatx, Inc. |
Rna antibodies
|
|
EP3638215A4
(en)
|
2017-06-15 |
2021-03-24 |
Modernatx, Inc. |
RNA FORMULATIONS
|
|
CA3070951C
(en)
|
2017-07-24 |
2023-03-21 |
Pharmosa Biopharm Inc. |
Liposome compositions comprising weak acid drugs and uses thereof
|
|
EP3668979A4
(en)
|
2017-08-18 |
2021-06-02 |
Modernatx, Inc. |
METHOD OF HPLC ANALYSIS
|
|
EP3668971B8
(en)
|
2017-08-18 |
2024-05-29 |
ModernaTX, Inc. |
Rna polymerase variants
|
|
EP3668977A4
(en)
|
2017-08-18 |
2021-04-21 |
Modernatx, Inc. |
HPLC ANALYTICAL PROCESSES
|
|
US20200254086A1
(en)
|
2017-08-18 |
2020-08-13 |
Moderna TX, Inc. |
Efficacious mrna vaccines
|
|
WO2019046809A1
(en)
*
|
2017-08-31 |
2019-03-07 |
Modernatx, Inc. |
METHODS OF MANUFACTURING LIPID NANOPARTICLES
|
|
US10653767B2
(en)
|
2017-09-14 |
2020-05-19 |
Modernatx, Inc. |
Zika virus MRNA vaccines
|
|
JP7308000B2
(ja)
|
2017-10-31 |
2023-07-13 |
モデルナティエックス インコーポレイテッド |
Ｖｅｇｆ－ａポリペプチドをコードする改変ｒｎａを送達するための脂質ナノ粒子
|
|
US20190192646A1
(en)
|
2017-11-03 |
2019-06-27 |
Modernatx, Inc. |
Salmonella vaccines
|
|
EP3713601A4
(en)
|
2017-11-21 |
2022-03-09 |
Modernatx, Inc. |
VACCINES AGAINST EPSTEIN-BARR VIRUS
|
|
WO2019148101A1
(en)
|
2018-01-29 |
2019-08-01 |
Modernatx, Inc. |
Rsv rna vaccines
|
|
EP4227319B1
(en)
|
2018-04-17 |
2025-11-26 |
CureVac SE |
Novel rsv rna molecules and compositions for vaccination
|
|
US12076439B2
(en)
|
2018-05-24 |
2024-09-03 |
Translate Bio, Inc. |
Thioester cationic lipids
|
|
KR20210038886A
(ko)
|
2018-06-27 |
2021-04-08 |
모더나티엑스, 인크. |
개인화된 암 백신 에피토프 선택
|
|
EP3813798A1
(en)
|
2018-06-28 |
2021-05-05 |
AstraZeneca AB |
Exosome extracellular vesicles and methods of use
|
|
US11357726B2
(en)
|
2018-08-29 |
2022-06-14 |
Translate Bio, Inc. |
Process of preparing mRNA-loaded lipid nanoparticles
|
|
WO2020056370A1
(en)
|
2018-09-13 |
2020-03-19 |
Modernatx, Inc. |
Modified mrna for the treatment of progressive familial intrahepatic cholestasis disorders
|
|
US12263248B2
(en)
|
2018-09-19 |
2025-04-01 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
MA53650A
(fr)
|
2018-09-19 |
2021-07-28 |
Modernatx Inc |
Lipides peg et leurs utilisations
|
|
AU2019345067A1
(en)
|
2018-09-19 |
2021-04-08 |
Modernatx, Inc. |
High-purity peg lipids and uses thereof
|
|
WO2020061457A1
(en)
|
2018-09-20 |
2020-03-26 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
EP4379053A3
(en)
|
2018-10-09 |
2024-09-18 |
The University of British Columbia |
Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto
|
|
WO2020081933A1
(en)
|
2018-10-19 |
2020-04-23 |
Translate Bio, Inc. |
Pumpless encapsulation of messenger rna
|
|
CA3118947A1
(en)
|
2018-11-07 |
2020-05-14 |
Modernatx, Inc. |
Rna cancer vaccines
|
|
CA3128215A1
(en)
|
2019-01-31 |
2020-08-06 |
Modernatx, Inc. |
Methods of preparing lipid nanoparticles
|
|
US11351242B1
(en)
|
2019-02-12 |
2022-06-07 |
Modernatx, Inc. |
HMPV/hPIV3 mRNA vaccine composition
|
|
CN113795579A
(zh)
|
2019-02-20 |
2021-12-14 |
摩登纳特斯有限公司 |
用于共转录加帽的rna聚合酶变体
|
|
KR20210149727A
(ko)
|
2019-03-11 |
2021-12-09 |
모더나티엑스, 인크. |
유가식(fed-batch) 시험관내 전사 공정
|
|
EP3938379A4
(en)
|
2019-03-15 |
2023-02-22 |
ModernaTX, Inc. |
Hiv rna vaccines
|
|
KR20220024022A
(ko)
|
2019-05-14 |
2022-03-03 |
트랜슬레이트 바이오 인코포레이티드 |
Mrna-로딩된 지질 나노입자를 제조하는 개선된 방법
|
|
MA56060A
(fr)
|
2019-05-31 |
2022-04-06 |
Modernatx Inc |
Dosage de lymphocytes t ayant subi une expansion
|
|
KR20220078557A
(ko)
|
2019-07-08 |
2022-06-10 |
트랜슬레이트 바이오 인코포레이티드 |
개선된 mrna 로딩된 지질 나노입자 및 이의 제조 방법
|
|
US12144871B2
(en)
|
2019-07-23 |
2024-11-19 |
Translate Bio, Inc. |
Stable compositions of MRNA-loaded lipid nanoparticles and processes of making
|
|
CN114269918A
(zh)
|
2019-08-14 |
2022-04-01 |
摩登纳特斯有限公司 |
用于纯化体外转录的下游产物的方法
|
|
AU2020346041A1
(en)
|
2019-09-11 |
2022-03-31 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
CN120423969A
(zh)
|
2019-09-19 |
2025-08-05 |
摩登纳特斯有限公司 |
用于治疗剂的细胞内递送的支链尾端脂质化合物和组合物
|
|
WO2021055811A1
(en)
|
2019-09-19 |
2021-03-25 |
Modernatx, Inc. |
Cap guides and methods of use thereof for rna mapping
|
|
US12053551B2
(en)
|
2019-12-20 |
2024-08-06 |
Translate Bio, Inc. |
Process of preparing mRNA-loaded lipid nanoparticles
|
|
US20210217484A1
(en)
|
2020-01-10 |
2021-07-15 |
Modernatx, Inc. |
Variational autoencoder for biological sequence generation
|
|
US20210228707A1
(en)
|
2020-01-28 |
2021-07-29 |
Modernatx, Inc. |
Coronavirus rna vaccines
|
|
US20230338506A1
(en)
|
2020-01-30 |
2023-10-26 |
Modernatx, Inc. |
Respiratory virus immunizing compositions
|
|
JP2023513043A
(ja)
|
2020-01-31 |
2023-03-30 |
モデルナティエックス インコーポレイテッド |
脂質ナノ粒子を調製する方法
|
|
AU2021215938A1
(en)
|
2020-02-07 |
2022-09-01 |
Modernatx, Inc. |
Sars-cov-2 mrna domain vaccines
|
|
JP7744354B2
(ja)
|
2020-02-25 |
2025-09-25 |
トランスレイト バイオ， インコーポレイテッド |
Ｍｒｎａ担持脂質ナノ粒子を調製する改善された方法
|
|
IL297084A
(en)
|
2020-04-09 |
2022-12-01 |
Suzhou Abogen Biosciences Co Ltd |
Lipid nanoparticle compounds
|
|
WO2021211343A1
(en)
|
2020-04-13 |
2021-10-21 |
Modernatx, Inc. |
Zika virus mrna vaccines
|
|
WO2021222304A1
(en)
|
2020-04-27 |
2021-11-04 |
Modernatx, Inc. |
Sars-cov-2 rna vaccines
|
|
EP4149484A4
(en)
|
2020-05-15 |
2024-10-02 |
ModernaTX, Inc. |
RNA FORMULATIONS FOR HIGH VOLUME DELIVERY
|
|
CA3183399A1
(en)
|
2020-05-15 |
2021-11-18 |
Translate Bio, Inc. |
Lipid nanoparticle formulations for mrna delivery
|
|
WO2021159130A2
(en)
|
2020-05-15 |
2021-08-12 |
Modernatx, Inc. |
Coronavirus rna vaccines and methods of use
|
|
US20230190761A1
(en)
|
2020-05-21 |
2023-06-22 |
Modernatx, Inc. |
Methylene blue stabilized mrna compositions
|
|
CA3185855A1
(en)
|
2020-06-05 |
2021-12-09 |
Modernatx, Inc. |
Bacterial strains for dna production
|
|
US20230277457A1
(en)
|
2020-08-06 |
2023-09-07 |
Modernatx, Inc. |
Methods of preparing lipid nanoparticles
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
EP4217371A1
(en)
|
2020-09-25 |
2023-08-02 |
ModernaTX, Inc. |
Multi-proline-substituted coronavirus spike protein vaccines
|
|
IL301973A
(en)
|
2020-10-12 |
2023-06-01 |
Translate Bio Inc |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
WO2022081548A1
(en)
|
2020-10-12 |
2022-04-21 |
Translate Bio, Inc. |
Improved process of preparing ice-based lipid nanoparticles
|
|
WO2022150717A1
(en)
|
2021-01-11 |
2022-07-14 |
Modernatx, Inc. |
Seasonal rna influenza virus vaccines
|
|
CA3208303A1
(en)
|
2021-01-15 |
2022-07-21 |
Modernatx, Inc. |
Variant strain-based coronavirus vaccines
|
|
CA3208486A1
(en)
|
2021-01-15 |
2022-07-21 |
Modernatx, Inc. |
Variant strain-based coronavirus vaccines
|
|
CA3212664A1
(en)
|
2021-03-05 |
2022-09-09 |
Modernatx, Inc. |
Vlp enteroviral vaccines
|
|
CN117677389A
(zh)
|
2021-03-26 |
2024-03-08 |
摩登纳特斯有限公司 |
百日咳疫苗
|
|
TW202304944A
(zh)
|
2021-03-31 |
2023-02-01 |
美商現代公司 |
用於產生ｍＲＮＡ之三核苷酸及四核苷酸帽的合成
|
|
AU2022249357A1
(en)
|
2021-04-01 |
2023-10-12 |
Modernatx, Inc. |
Methods for identification and ratio determination of rna species in multivalent rna compositions
|
|
WO2022212191A1
(en)
|
2021-04-01 |
2022-10-06 |
Modernatx, Inc. |
Mucosal expression of antibody structures and isotypes by mrna
|
|
WO2022221336A1
(en)
|
2021-04-13 |
2022-10-20 |
Modernatx, Inc. |
Respiratory syncytial virus mrna vaccines
|
|
US20240216500A1
(en)
|
2021-04-13 |
2024-07-04 |
Modernatx, Inc. |
Respiratory virus combination vaccines
|
|
JP2024514183A
(ja)
|
2021-04-13 |
2024-03-28 |
モデルナティエックス インコーポレイテッド |
エプスタイン－バーウイルスｍＲＮＡワクチン
|
|
AU2022258463A1
(en)
|
2021-04-14 |
2023-11-23 |
Modernatx, Inc. |
Influenza-coronavirus combination vaccines
|
|
EP4329731A1
(en)
|
2021-04-29 |
2024-03-06 |
ModernaTX, Inc. |
Lyophilization methods for preparing lipid formulated therapeutics
|
|
US20220363937A1
(en)
|
2021-05-14 |
2022-11-17 |
Armstrong World Industries, Inc. |
Stabilization of antimicrobial coatings
|
|
US20240293534A1
(en)
|
2021-06-14 |
2024-09-05 |
Modernatx, Inc. |
Coronavirus glycosylation variant vaccines
|
|
WO2022266010A1
(en)
|
2021-06-14 |
2022-12-22 |
Modernatx, Inc. |
Mrna vaccines encoding flexible coronavirus spike proteins
|
|
WO2022266389A1
(en)
|
2021-06-17 |
2022-12-22 |
Modernatx, Inc. |
Alternative rna purification strategies
|
|
WO2023283645A1
(en)
|
2021-07-09 |
2023-01-12 |
Modernatx, Inc. |
Pan-human coronavirus domain vaccines
|
|
WO2023283642A2
(en)
|
2021-07-09 |
2023-01-12 |
Modernatx, Inc. |
Pan-human coronavirus concatemeric vaccines
|
|
EP4366768A4
(en)
|
2021-07-09 |
2025-05-21 |
ModernaTX, Inc. |
Pan-human coronavirus vaccines
|
|
TW202320737A
(zh)
|
2021-07-26 |
2023-06-01 |
美商現代公司 |
製備用於將酬載分子遞送至氣道上皮之脂質奈米粒子組成物之製程
|
|
WO2023009421A1
(en)
|
2021-07-26 |
2023-02-02 |
Modernatx, Inc. |
Processes for preparing lipid nanoparticle compositions
|